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| 1 | Mesenchymal stem cells: Emerging mechanisms of immunomodulation and therapy显示文摘Mesenchymal stem cells(MSCs) are a pleiotropic population of cells that are self-renewing and capable of differentiating into canonical cells of the mesenchyme, including adipocytes, chondrocytes, and osteocytes. They employ multi-faceted approaches to maintain bone marrow niche homeostasis and promote wound healing during injury. Biomedical research has long sought to exploit their pleiotropic properties as a basis for cell therapy for a variety of diseases and to facilitate hematopoietic stem cell establishment and stromal reconstruction in bone marrow transplantation. Early results demonstrated their usage as safe, and there was little host response to these cells. The discovery of their immunosuppressive functions ushered in a new interest in MSCs as a promising therapeutic tool to suppress inflammation and down-regulate pathogenic immune responses in graft-versus-host and autoimmune diseases such as multiple sclerosis, autoimmune diabetes, and rheumatoid arthritis. MSCs produce a large number of soluble and membrane-bound factors, some of which inhibit immune responses. However, the full range of MSC-mediated immune-modulation remains incompletely understood, as emerging reports also reveal that MSCs can adopt an immunogenic phenotype, stimulate immune cells, and yield seemingly contradictory results in experimental animal models of inflammatory disease. The present review describes the large body of literature that has been accumulated on the fascinating biology of MSCs and their complex effects on immune responses. | Justin D Glenn Katharine A Whartenby | 2014 | World Journal of Stem Cells2014，6，5： | 55 |
| 2 | 维生素C、E对中华绒螯蟹生殖性能的影响显示文摘通过对河蟹雌性亲体投喂不添加或添加VC、VE的4组实验饲料,并以新鲜河蚌为对照,进行198d饲养试验,以雌蟹性腺系数、产卵力、孵化率以及各组织中SOD活性、MDA含量等指标作为判据,研究了VC、VE对雌蟹生殖性能的影响。结果表明,1(投喂添加0.5mg·(100g)-1VC饲料组)、2(投喂添加0.022mg·(100g)-1VE饲料组)和3(投喂添加0.5mg·(100g)-1VC饲料和0.022mg·(100g)-1VE饲料组)3个组雌蟹的产卵力分别为3620个卵细胞·g-1体重、3540个卵细胞·g-1体重、3710个卵细胞·g-1体重,孵化率分别是83.03%、84.06%、86.27%,均极显著高于4组(投喂未添加维生素饲料组)雌蟹的产卵力(2490个卵细胞·g-1体重)和孵化率(29.28%)(P<0.01),也显著高于5组(饲喂河蚌)雌蟹的产卵力(3010个卵细胞·g-1体重)和孵化率(71.12%)(P<0.05)。雌蟹卵巢中SOD活性,1、2和3组则比4组和5组显著低(P<0.05),分别为56.35Nu·mL-1、53.61Nu·mL-1和39.87Nu·mL-1,相应地,MDA含量分别为6.03nmol·mL-1、5.65nmol·mL-1和5.57nmol·mL-1;4组雌蟹,虽然其卵巢中SOD活性较高,达79.25Nu·mL-1,但因饲料中缺乏抗氧化性的VC、VE,引发卵子脂质过氧化,MDA含量显著增加(P<0.05),为23.18nmol·mL-1,导致卵质低下,从而影响了卵子孵化。综上所述。 | 艾春香 陈立侨 周忠良 Glenn Y Deng 江洪波 | 2003 | 水产学报2003，27，1： | 31 |
| 3 | 城市生态网络功能性连接辨识方法显示文摘城市生态网络是景观生态学应用领域研究的热点和重点之一,识别、评估生境之间的连接是构建生态网络的关键环节。在总结已有连接辨识方法的基础上,提出采用最小费用模型和图论分析相结合的方法,探讨功能性连接的辨识和优先恢复途径。以新西兰基督城为案例,分别利用景观发展强度指数建立阻力面,新西兰鸡毛松(Dacrycarpus dacrydioides)种子最大传播距离作为连接阈值来模拟、评价网络连接。结果表明:在1200 m距离阈值下,共有408条连接,其重要性分为10类。其中Richmond—Petrie公园,Hansons—Auburn保护地,Centaurus公园—King George保护地是整个生态网络的关键连接;若去除,景观整体连接度将下降31.73%。此外,研究发现连接重要值与两端的源面积之和没有显著相关性,即面积大的源斑块之间的连接不一定对网络构建起关键作用,这一结论还有待进一步证明。针对缺少动物迁移资料的城市环境,改进最小费用模型和网络连接分析的部分参数;可操作性与实用性强,对中国城市区域生态恢复建设、栖息地选择具有借鉴意义。 | 陈春娣 Meurk D. Colin Ignatieva E. Maria Stewart H. Glenn 吴胜军 | 2015 | 生态学报2015，35，19： | 25 |
| 4 | 全海水灌溉的作物——北美海蓬子(下)显示文摘 | 吕忠进 Edward P. Glenn Roy M. Hodges Carl Hodges | 2001 | 世界农业2001，，3： | 20 |
| 5 | 美国退伍军人事务部/国防部成人脑卒中康复治疗管理临床实践指南(执行简写版)显示文摘背景专家委员会制定的卒中康复指南应用于退伍军人健康管理部门及国防部卫生保健系统。方法根据以前发表的指南,委员会利用美国预防服务特别工作组制定的标准,评价了截至到2002年发表的文献。指南根据临床随机化实验、非对照性研究等证据提出建议(如缺乏确定的数据则根据专家组的建议)。结果Ⅰ级水平的建议包括:在多学科康复环境中或卒中单元中传递卒中治疗,通过NI HSS对卒中患者进行评价,早期启动康复治疗,对吞咽困难患者进行吞咽功能筛查,积极进行二级预防,预防深静脉血栓等。推荐应用标准化的评价工具制定适合每个患者的全面的治疗计划。强烈建议进行抗抑郁及情感波动方面的治疗。语言治疗师应评价患者的交流及认知障碍,并在需要时提供治疗。患者、家属及护理者是康复小组的重要成员,应当介入康复的全部疗程。这些建议在以下网站可查询:http://gffzz5f80cf956d2d4616hxxxxqkf9xf6b6pp0.ffgz.tsg.suse.edu.cn/cgi/content/full/36/9/e100。并附有每项建议的全文证据表。结论这些建议应平等地应用于所有临床环境中的所有卒中康复患者,而不是仅针对联邦医疗系统的临床问题或资源。 | Barbara Bates John Y. Choi Pamela W. Duncan Jonathan J. Glasberg Glenn D. Graham Richard C. Katz Kerri Lamberty Dean Reker Richard Zorowitz 杨雅琴(译) 王拥军(译) | 2006 | 中国康复理论与实践2006，12，1： | 19 |
| 6 | 制冷剂特性数据解析与更新显示文摘介绍制冷剂主要的物理特性、安全性、环境特性等方面的数据,这些制冷剂包括过去广泛使用的、当前普遍使用的以及将来使用的。 | James M.Calm Glenn C.Hourahan 白雪莲 | 2007 | 制冷与空调2007，7，5： | 11 |
| 7 | 睾酮和代谢综合症显示文摘关于代谢综合症的诊断价值始终存在争议。很多代谢综合症的相关因素亦被认定为心血管疾病的风险因素。尽管代谢综合征的诊断标准包括胰岛素抵抗,但其发生率并不普遍。伴有肥胖和腰围增大的高胰岛素血症及高炎症因子状态可以很好的解释代谢综合症患者的低睾酮和低性激素结合蛋白(SHBG)水平。低SHBG水平可以预测代谢综合症的发病率;低睾酮水平是心血管疾病的风险因素,但不一定是发病因素。国际糖尿病学会推荐的治疗代谢综合症的策略包括心血管风险评估、生活方式及饮食习惯的改善、锻炼、控制体重、以及个体性风险因素的控制等。然而,代谢综合症患者很少可以有效控制自己的体重。近来,有研宄发现睾酮补充可以减轻体重、减少腰围、胰岛素增敏、改善血红蛋白A1c水平,甚至改善代谢综合症的所有发病因素。同时,也有一些观察性研究结果显示睾酮补充会导致心血管事件发生率升高,对此FDA进行了详细追踪,结果显示此类报道有侍商椎。目前,大样本随机对照研究亟待开展,用以验证睾酮补充疗法治疗伴有睾酮水平低下的中老年代谢综合症患者的安全性及有效性。 | Glenn R Cunningham | 2015 | Asian Journal of Andrology2015，17，2： | 9 |
| 8 | 硒的价态与浓度水平对6种植物种子发芽和根际生长的影响显示文摘本文研究了硒的价态(Se6+和Se4+)和浓度水平(0~100mgSe·L-1)对6种植物(大麦、小麦、花椰菜、萝卜、苜蓿和欧芹)种子萌发和根际生长特性的影响。结果表明,低浓度硒(<1mgSe·L-1)对种子发芽促进作用不明显,而高浓度硒(>4mgSe·L-1)则有显著抑制作用,不同种子对硒的抗性表现不同。根长和芽长的测定结果表明,低浓度对花椰菜和小麦种子生长具有显著促进作用,对欧芹种子表现出抑制作用。较高浓度(1~4mg·L-1)即对花椰菜、苜蓿和欧芹的根生长表现出抑制作用,高浓度对小麦、大麦和萝卜根生长有抑制作用,且使芽生长受到抑制的硒浓度高于根生长。比较价态,低硒时六价对花椰菜生长的促进作用显著高于四价,高硒时小麦和苜蓿对硒的抗性表现为六价硒强于四价硒,其余科属差异不显著。不同科属对硒的抗性为禾本科小麦和大麦最强,十字花科花椰菜和萝卜次之,豆科苜蓿较差,伞形科欧芹最差。 | 毛晖 王朝辉 Graham Lyons Glenn McDonald | 2011 | 农业环境科学学报2011，30，10： | 8 |
| 9 | 基因转移载体脂质体和重组腺病毒介导碱性磷酸酶基因在B16F1细胞中的表达比较显示文摘目的 :探讨两种基因转移载体脂质体转染的和重组腺病毒收集并转导的SEAP基因在B16F1细胞中的表达动态。方法 :脂质体和质粒DNA复合后 ,转染 10 6 B16F1细胞 ,连续 5d收集并换细胞培养液 ,并检测其中的SEAP酶活性。将重组腺病毒以 10 0 0m .o .i、2 0 0 0m .o .i、3 0 0 0m .o .i、4 0 0 0m .o .i接种B16F1细胞 ,连续 5d收集并换细胞培养液 ,并检测其中SEAP的含量。结果 :随着时间的推移 ,脂质体转染的SEAP的表达逐渐下降 ,由第 1天的 82 1.6μUnit/ml下降到第 5天的 2 75 .2 μUnit/ml。腺病毒转导的SEAP的表达却是逐渐上升。并随接种毒量的增加而上升。且第三、四天表达达最高后 ,能保持较稳定的水平。接种 4 0 0 0m .o .i组 ,SEAP的表达由第 1天的93 .9μUnit/ml上升到第 3天 12 81.1μUnit/ml。到第 5天仍为 12 4 0 .4 μUnit/ml。结论 :脂质体和重组腺病毒作为不同的基因转移载体都能有效地介导外源基因的转移入靶细胞 ,并使外源基因在靶细胞内获得有效地表达。 | 刘金辉 Glenn Larsen | 2002 | 江西医学院学报2002，42，2： | 8 |
| 10 | Under the surface:Pressure-induced planetary-scale waves,volcanic lightning,and gaseous clouds caused by the submarine eruption of Hunga Tonga-Hunga Ha'apai volcano显示文摘We present a narrative of the eruptive events culminating in the cataclysmic January 15, 2022 eruption of Hunga Tonga-Hunga Ha’apai Volcano by synthesizing diverse preliminary seismic, volcanological, sound wave, and lightning data available within the first few weeks after the eruption occurred. The first hour of eruptive activity produced fast-propagating tsunami waves, long-period seismic waves, loud audible sound waves, infrasonic waves, exceptionally intense volcanic lightning and an unsteady volcanic plume that transiently reached-at 58km-the Earth’s mesosphere. Energetic seismic signals were recorded worldwide and the globally stacked seismogram showed episodic seismic events within the most intense periods of phreatoplinian activity, and they correlated well with the infrasound pressure waveform recorded in Fiji. Gravity wave signals were strong enough to be observed over the entire planet in just the first few hours, with some circling the Earth multiple times subsequently. These large-amplitude, long-wavelength atmospheric disturbances come from the Earth’s atmosphere being forced by the magmatic mixture of tephra, melt and gasses emitted by the unsteady but quasicontinuous eruption from 0402±1–1800 UTC on January 15, 2022. Atmospheric forcing lasted much longer than rupturing from large earthquakes recorded on modern instruments, producing a type of shock wave that originated from the interaction between compressed air and ambient(wavy) sea surface. This scenario differs from conventional ideas of earthquake slip, landslides, or caldera collapse-generated tsunami waves because of the enormous(~1000x) volumetric change due to the supercritical nature of volatiles associated with the hot,volatile-rich phreatoplinian plume. The time series of plume altitude can be translated to volumetric discharge and mass flow rate. For an eruption duration of ~12 h, the eruptive volume and mass are estimated at 1.9 km^(3) and~2 900 Tg, respectively, corresponding to a VEI of 5–6 for this event. The high frequency and intensity of lightning was enhanced by the production of fine ash due to magma-seawater interaction with concomitant high charge per unit mass and the high pre-eruptive concentration of dissolved volatiles. Analysis of lightning flash frequencies provides a rapid metric for plume activity and eruption magnitude. Many aspects of this eruption await further investigation by multidisciplinary teams. It represents a unique opportunity for fundamental research regarding the complex, non-linear behavior of high energetic volcanic eruptions and attendant phenomena, with critical implications for hazard mitigation, volcano forecasting, and first-response efforts in future disasters. | David A.Yuen Melissa A.Scruggs Frank J.Spera Yingcai Zheng Hao Hu Stephen R.McNutt Glenn Thompson Kyle Mandli Barry R.Keller Songqiao Shawn Wei Zhigang Peng Zili Zhou Francesco Mulargia Yuichiro Tanioka | 2022 | Earthquake Research Advances2022，2，3： | 7 |
| 11 | The Friction - Reducing, Antiwear and Antioxidation Properties of an Organo- Molybdenum Lube Additive without Sulfur and Phosphorus显示文摘 | Junbing Yao Gaston Aguilar Glenn A. Mazzamaro | 2007 | 润滑油2007，22，3： | 7 |
| 12 | Seasonal changes of soil erosion and its spatial distribution on a long gentle hillslope in the Chinese Mollisol region显示文摘Understanding seasonal soil erosion and deposition rates and their spatial distribution along sloping farmlands are necessary for erosion prediction technology and implementing effective soil conservation practices.To date seasonal change of soil erosion and soil redistribution on long gentle hillsiopes are not fully quantified due to the variable erosive forces in different seasons.A multi-tracer method using rare earth elements(REE)was employed to discriminate seasonal changes of soil erosion and its spatial distribution on a sloping farmland driven by snowmelt runoff,wind force and rainfall-runoff.A long-slope runoff plot with 5 m wide and 320 m long located in the typical Mollisol region of China was divided into eight segments,each of which was 40 m long and tagged with one of eight REE oxides.The spot method of a partial-area tagging scheme was employed and a grid-based layout was used for REE application.Results showed that annual soil erosion rate was 3251.01 km^(-2)for the whole runoff plot,in which snowmelt runoff erosion contributed 537.3 t km^(-2),wind erosion 363.11 km-2 and rainfall-runoff erosion 2350.6 t km^(-2).Surface runoff is the main external erosive force of hillslope soil erosion,accounting for 88.8%of the total annual soil loss.Furthermore,for the eight slope segments of the 320-m long hillslope,the sediment transport ratios of each slope segment caused by snowmelt runoff and rainfall-runoff erosion were more than 23.5%and 34.7%,respectively.The results will enrich the understanding of seasonal soil erosion on long hillsiopes. | Lei Wang Fenli Zheng Gang Liu Xunchang J.Zhang Glenn V.Wilson Hongqiang Shi Xujun Liu | 2021 | International Soil and Water Conservation Research2021，9，3： | 6 |
| 13 | The Mediterranean diet improves hepatic steatosis and insulin sensitivity in individuals with non-alcoholic fatty liver disease显示文摘 | Marno C. Ryan Catherine Itsiopoulos Tania Thodis Glenn Ward Nicholas Trost Sophie Hofferberth Kerin O’Dea Paul V. Desmond Nathan A. Johnson Andrew M. Wilson | 2013 | Journal of Hepatology2013，，1： | 6 |
| 14 | CHAPTER 1: AUA GUIDELINE ON MANAGEMENT OF STAGHORN CALCULI: DIAGNOSIS AND TREATMENT RECOMMENDATIONS显示文摘 | GLENN M. PREMINGER DEAN G. ASSIMOS JAMES E. LINGEMAN STEPHEN Y. NAKADA MARGARET S. PEARLE J. STUART WOLF | 2005 | The Journal of Urology2005，，6： | 6 |
| 15 | Aging:A mitochondrial DNA perspective,critical analysis and an update显示文摘The mitochondrial theory of aging, a mainstream theory of aging which once included accumulation of mitochondrial DNA(mt DNA) damage by reactive oxygen species(ROS) as its cornerstone, has been increasingly losing ground and is undergoing extensive revision due to its inability to explain a growing body of emerging data. Concurrently, the notion of the central role for mtDNA in the aging process is being met with increased skepticism. Our progress in understanding the processes of mtDNA maintenance, repair, damage, and degradation in response to damage has largely refuted the view of mt DNA as being particularly susceptible to ROS-mediated mutagenesis due to its lack of 'protective' histones and reduced complement of available DNA repair pathways. Recent research on mitochondrial ROS production has led to the appreciation that mitochondria, even in vitro, produce much less ROS than previously thought, automatically leading to a decreased expectation of physiologically achievable levels of mtDNA damage. New evidence suggests that both experimentally induced oxidative stress and radiation therapy result in very low levels of mtDNA mutagenesis. Recent advances provide evidence against the existence of the 'vicious' cycle of mtDNA damage and ROS production. Meta-studies reveal no longevity benefit of increased antioxidant defenses. Simultaneously, exciting new observations from both comparative biology and experimental systems indicate that increased ROS production and oxidative damage to cellular macromolecules, including mtDNA, can be associated with extended longevity. A novel paradigm suggests that increased ROS production in aging may be the result of adaptive signaling rather than a detrimental byproduct of normal respiration that drives aging. Here, we review issues pertaining to the role of mtDNA in aging. | Inna N Shokolenko Glenn L Wilson Mikhail F Alexeyev | 2014 | World Journal of Experimental Medicine2014，4，4： | 6 |
| 16 | Millisecond synthesis of CoS nanopartides for highly efficient overall water splitting显示文摘High performance and low-cost electrocatalysts for overall water splitting,i.e.,catalyzing hydrogen and oxygen evolution reactions with the same material,are of great importance for large-scale,renewable energy conversion processes.Here,we report an ultrafast(~7 ms)synthesis tech nique for tran sition metal chalcoge nide n anoparticles assisted by high temperature treatme nt.As a proof of con cept,we dem on strate that cobalt sulfide(~20 nm in diameter)@few-layer graphe ne(~2 nm in thick ness)core-shell nan oparticles embedded in RGO nano sheets exhibit remarkable bifunctional electrocatalytic activity and stability for overall water splitting,which is comparable to commercial 40 wt.%platinum/carbon(Pt/C)electrocatalysts.After 60 h of continuous operation,10 mA crrT?water splitting current density can still be achieved at a low potential of^1.77 V without any activity decay,which is among the most active for non-noble material based electrocatalysts.The presented study provides prospects in synthesizing highly efficient bifunctional electrocatalysts for large-scale energy conversion application via a simple yet efficient technique. | Yanan Chen Shaomao Xu Shuze Zhu Rohit Jiji Jacob Glenn Pastel Yanbin Wang Yiju Li Jiaqi Dai Fengjuan Chen Hua Xie Boyang Liu Yonggang Yao Lourdes G. Salamanca-Riba Michael R. Zachariah Teng Li Liangbing Hu | 2019 | Nano Research2019，12，9： | 6 |
| 17 | Micro RNAs in the development of non-alcoholic fatty liver disease显示文摘Nonalcoholic fatty liver disease or nonalcoholic fatty liver disease(NAFLD) refers to a group of disorders that arise from the accrual of fat in hepatocytes. Although various factors have been associated with the development of NAFLD, including genetic predisposition and environmental exposures, little is known aboutthe underlying pathogenesis of the disease. Research efforts are ongoing to identify biological targets and signaling pathways that mediate NAFLD. Emerging evidence has implicated a role for micro RNAs(mi RNAs), short single-stranded molecules that regulate gene expression either transcriptionally, through targeting of promoter regions, or post-transcriptionally, by blocking translation or promoting cleavage of specific target m RNAs. Several mi RNAs have been associated with NAFLD, although our understanding of the biology underlying their role is still emerging. The goal of this review is to present an overview of the current state of knowledge of mi RNAs involved in the development of NAFLD across a range of in vitro and in vivo models, including mi RNAs that contribute to pathological mechanisms related to fatty liver in humans. Much less is known about the specific targets of mi RNAs in cells, nor the molecular mechanisms involved in the development and progression NAFLD and related outcomes. More recently, the identification and validation of mi RNA signatures in serum may facilitate the development of improved methods for diagnosis and clinical monitoring of disease progression. | Glenn S Gerhard Johanna K DiStefano | 2015 | World Journal of Hepatology2015，7，2： | 5 |
| 18 | WONCA研究论文摘要汇编——减少食盐对心血管疾病的预防作用显示文摘背景美国饮食含盐量高,多数为加工食品。减少食盐的摄入是公众健康的重要目标。方法本研究使用冠心病策略模式,将全人群食盐减少到3g/d(钠1200mg/d)潜在的获益进行量化。评价年龄、性别、种族亚组的心血管病发生率和成本,将减少食盐与其他减少心血管风险的干预方法进行对照;将减少食盐与高血压药物治疗做对照确定成本效应。结果每日减少食盐3g,预计可减少年度新发病例:冠心病6.0万~12.0万例、脑卒中3.2万~6.6万例、心肌梗死5.4万~9.9万例;且可使年度全因死亡患者数目减少4.4万~9.2万。任何人群均可获益,黑人获益比例最高。女性,尤其脑卒中、老年冠心病、年纪较轻者病死率下降明显。摄入盐减少的心血管益处与减少吸烟、肥胖和胆固醇水平所带来的益处相同。所设计的调整干预项可达到每日摄入盐减少3g,并可节省医疗成本100亿~240亿美元。即使在2010—2019年,此干预项逐渐达到每日适度减少食盐1g也能削减医疗成本,与高血压患者降压用药相比,更具有成本效应。结论适度减少食盐可减少心血管事件和医疗成本,应该成为维护公众健康的目标。 | Kirsten Bibbins-Domingo Glenn MChertow Pamela G Coxson 周淑新(译) | 2010 | 中国全科医学2010，13，32： | 5 |
| 19 | 发动机油非磷抗氧、抗磨、减摩添加剂协同研究显示文摘降低发动机油的磷含量,提高燃料经济性,延长使用寿命,已是润滑油升级换代大势所趋。为了降低磷的含量,必须减少二烷基二硫代磷酸锌(ZnDDP)的使用,而二烷基二硫代氨基甲酸锌(ZnDDC)是ZnDDP最理想的替代物。为了提高油品的燃料经济性,需要加入有机钼摩擦改进剂,其中,不含硫磷的钼酸酯添加剂,因其良好的减摩保持性,其应用更为突出。为了满足更苛刻的油品高温性能要求,还必须加入烷基化二苯胺类抗氧剂(AD-PA)。因此有必要对非活性钼、ZnDDC和ADPA之间相互作用进行考察。研究表明,在非活性有机钼、ZnDDC、ADPA的三元添加剂体系中,存在着三种相互配合的协同作用:ZnDDC与非活性有机钼的抗磨协同,非活性有机钼与ADPA的抗氧化协同,以及ZnDDC与ADPA的抗氧化协同。利用非活性有机钼、ZnDDC、ADPA的三元非磷协同复合体系(OD 0401),可以大幅度提高油品的抗氧化性能、减摩性能和抗磨性能,这对发展低磷含量的GF-4和GF-5发动机润滑油具有十分积极的意义。利用该协同复合添加剂OD 0401,还可以有效地提高低档发动机油的抗氧化和抗磨性能。 | 姚俊兵 Glenn A.Mazzamaro Gaston Aguilar Steve G.Donnelly | 2008 | 润滑油2008，23，2： | 5 |
| 20 | 菲律宾大马尼拉市气候因素与登革热发病率的相关性分析显示文摘在菲律宾大马尼拉,登革热是一个严重的公共卫生问题。持续攀升的登革热发病率已被归因于气候变化;然而,与之相矛盾的报告称,登革热与气候因素之间的显著的相关关系并不存在。为了进一步说明此二者的关系,本研究考察了1996~2005年,大马尼拉市地区的气温和降水两个气候因素对登革热发病率的影响。收集了10年间(1996~2005)大马尼拉地区登革热月发病率和气候数据。对温度和降水两个气候因素与登革热发病率之间的联系进行回归分析。预测模型(登革热发病率为Y,降水为X)显示,降水与登革热发病率显著相关(r^2=0.377,p<0.05);而温度与登革热发病率之间不存在显著的相关关系(p>0.05)。有证据显示,大马尼拉地区登革热发病率随着降水模式的改变而变化。建议加强降水丰富期对蚊子的监控。 | Glenn L. Sia Su 哈艳梅(译) 马泽清(译) | 2008 | AMBIO-人类环境杂志2008，37，4： | 5 |
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