维普中文期刊产品整合服务
870篇 您的检索式:作者名="GILSON"
    题名 作者 年代 出处 被引量
1卫生政策与体系研究概述显示文摘1卫生政策与体系研究的内涵 1.1定义与特点 卫生政策与体系研究(Health policy and systems research,HPSR)通常定义为“……通过提升社会组织能力来实现人群的健康目标,并研究不同社会角色对政策制定和执行的影响以及对政策成果的贡献。卫生政策与体系研究属于交叉学科,综合运用经济学、社会学、人类学、政治学、公共卫生和流行病学等学科,揭示卫生体系如何影响并适应卫生政策,以及卫生政策、健康相关因素与卫生体系之间如何相互影响”。Lucy Gilson 2013中国卫生政策研究2013,6,1:13
2The human TTAGGG repeat factors I and 2 bind to a subsetof interstitial telomeric sequences and satellite repeats显示文摘Thomas Simonet Laure-Emmanuelle Zaragosi Claude Philippe Kevin Lebrigand Cldmentine Schouteden Adeline Augereau Serge Bauwens Jing Ye Marco Santagostino Elena Giulotto Frederique Magdinier Beatrice Horard Pascal Barbry Rainer Waldmann Eric Gilson 2011Cell Research2011,21,7:7
3Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms显示文摘The infusion of coronavirus disease 2019(COVID-19)patients with mesenchymal stem cells(MSCs)potentially improves clinical symptoms,but the underlying mechanism remains unclear.We conducted a randomized,single-blind,placebo-controlled(29 patients/group)phase II clinical trial to validate previous findings and explore the potential mechanisms.Patients treated with umbilical cord-derived MSCs exhibited a shorter hospital stay(P=0.0198)and less time required for symptoms remission(P=0.0194)than those who received placebo.Based on chest images,both severe and critical patients treated with MSCs showed improvement by day 7(P=0.0099)and day 21(P=0.0084).MSC-treated patients had fewer adverse events.MSC infusion reduced the levels of C-reactive protein,proinflammatory cytokines,and neutrophil extracellular traps(NETs)and promoted the maintenance of SARS-CoV-2-specific antibodies.To explore how MSCs modulate the immune system,we employed single-cell RNA sequencing analysis on peripheral blood.Our analysis identified a novel subpopulation of VNN2+hematopoietic stem/progenitorlike(HSPC-like)cells expressing CSF3R and PTPRE that were mobilized following MSC infusion.Genes encoding chemotaxis factors—CX3CR1 and L-selectin—were upregulated in various immune cells.MSC treatment also regulated B cell subsets and increased the expression of costimulatory CD28 in T cells in vivo and in vitro.In addition,an in vivo mouse study confirmed that MSCs suppressed NET release and reduced venous thrombosis by upregulating kindlin-3 signaling.Together,our results underscore the role of MSCs in improving COVID-19 patient outcomes via maintenance of immune homeostasis.Rongjia Zhu Tingdong Yan Yingmei Feng Yan Liu Hongcui Cao Gongxin Peng Yanlei Yang Zhen Xu Jingqi Liu Wei Hou Xiaoyue Wang Zhe Li Luchan Deng Shihua Wang Jing Li Qin Han Hongling Li Guangliang Shan Yinghao Cao Xingyan An Jianshe Yan Zhonghui Zhang Huafei Li Xuebin Qu Jiaqi Zhu Shumin Zhou Jiao Wang Fengchun Zhang Jinming Gao Ronghua Jin Dayong Xu Yan-Qing Ma Tao Huang Shuang Peng Zhi Zheng Ilia Stambler Eric Gilson Lee Wei Lim Alexey Moskalev Antonio Cano Sasanka Chakrabarti Brun Ulfhake Huanxing Su Haoying Xu Sihuan Xu Feng Wei Holly MBrown-Borg Kyung-Jin Min Georgina Ellison-Hughes Calogero Caruso Kunlin Jin Robert Chunhua Zhao 2021Cell Research2021,31,12:5
4卫生政策分析:概念和方法的思考与挑战显示文摘许多专家学者就卫生政策分析开展了大量研究,但很少关注如何进行政策分析以及需要什么样的研究设计、理论和方法。本文着眼于卫生政策分析的环境以及面临的挑战,借鉴中低收入国家中一些卫生政策分析的框架、理论、方法和设计,列举了最近的研究案例,并探讨了案例研究的意义以及研究设计的必要性,发现卫生政策研究者的角色、反思和定位在研究过程中非常重要。最后从理论、方法学和研究人员的反思等角度提出了促进卫生政策分析的建议。Gill Walt Jeremy Shiffman Helen Schneider Susan F Murray Ruairi Brugha Lucy Gilson 2012中国卫生政策研究2012,5,12:3
5Pancreatic Resection of Isolated Metastases from Nonpancreatic Primary Cancers显示文摘Sushanth Reddy MD Barish H. Edil MD John L. Cameron MD Timothy M. Pawlik MD MPH Joseph M. Herman MD Marta M. Gilson PhD Kurtis A. Campbell MD Richard D. Schulick MD Nita Ahuja MD Christopher L. Wolfgang MD PhD 2008Annals of Surgical Oncology2008,,11:2
6最新进展:性传播感染显示文摘性传播疾病的发病率逐渐增高,特别是在15~25岁的人群当中。虽然,最近开发的一些筛查试验,尤其是对沙眼衣原体、单纯疱疹病毒和人乳头状瘤病毒的检测,为早期诊断和预防性传播感染及其并发症提供了新的机遇,但如何才能很好地控制性病增长的问题尚未解决。虽然这些筛查方法已用于研究,但用于临床实践仍是一个复杂的问题。本文叙述目前应用的对主要性传播性疾病的筛选试验,并讨论有关处理这些疾病的一些重要问题。RichardJ C Gilson Adrian Mindel 范洪伟 2003英国医学杂志中文版2003,6,1:2
7What leaders need to know: A review of social and contextual factors that can foster or hinder creativity显示文摘Christina E Shalley Lucy L Gilson 2004The Leadership Quarterly2004,,1:2
8Morphology and kinetics of the three distinct phases of red blood cell invasion by Plasmodium falciparum merozoites显示文摘Gilson PR Crabb BS 2009International Journal for Parasitology2009,39,1:1
9Matching Creativity Requirements and the Work Environment:Effects on Satisfaction and Intention to Leave显示文摘SHALLEYCE GILSON L L BLUM T C 0,,02:1
10Activation of ER stress by hydrogen peroxide in C2C12 myotubes显示文摘Pierre N Barbe C Gilson H 2014Biochem Bio phys Res Commun2014,450,1:1
11Empowerment and team effectiveness: An empirical test of an inte- grated model显示文摘Mathieu J E Gilson L L Ruddy T M 2006Journal of Applied Psychology2006,91,1:1
12Removing user fees for primary care in Africa: The need for careful action显示文摘Gilson L McIntyre D 2005British Medical Journal2005,331,:1
13Transplanted glial cells migrate over a greater distance and remyelinate demyelinated lesions more rapidly than endogenous remyelinating cells显示文摘Blakemore WF Gilson JM Crang AJ 2000J Neurosci Res2000,61,3:1
14Bankruptcy,boards and blockholders显示文摘Gilson S 1990Journal of Financial Economics1990,27,:1
15Acute pancreatitis related to tigecycline: case report and review of the literature显示文摘Gilson M Moachon L Jeanne L 2008Scand J Infect Dis2008,40,8:1
16Team Effectiveness 1997-2007:A Review of Recent Advancements and a Glimpse into the Future显示文摘Mathieu J Maynard M.T Rapp T Gilson L 0,,3:1
17Chemical equiubrium controlled etching of MF1- type zeolite and its influence on zeolite structure, acidity, and catalytic activity 显示文摘Gilson J P Qin Z Lakiss L 2013Chemistry of Materials : A Publication of the American Chemistry Society2013,25,14:1
18A little creativity goes a long way: Anexamination of teams’ engagement in creative processes 显示文摘Gilson LL Shalley CE 2004Journalof Management2004,30,4:1
19Integrated risk management: a Petrobras application in offshore well construction safety to minimize critical emergency disconnections显示文摘In order to avoid mistakes and to save a great deal of time in analysis, an innovative methodology was developed that can analyze the well operations and rig characteristics involved to define the best emergency disconnect sequence(EDS)available. A solution was developed based on the characteristics of the rigs and blowout preventers(BOPs), and six variables were considered that directly affect the choice of EDS. All possible combinations of 64 scenarios were analyzed,and the priority of choice of the EDS was defined empirically. This paper presents an approach to EDS risk management and examples of exposure time(time without riser safety margin and shear capability) for the same well, which can be lowered from 13% to 0.1%. The impact of this reduction is related to the ability of the BOP to cut some of the heavy casings, in addition to improved availability of EDS modes. This implementation opened up many possibilities for the performance of risk exposure analysis, enabling comparison of several BOP configurations of contracted rigs and selection of the best options. This innovative approach allowed a better management of the rig schedules, prioritizing safety aspects and making it possible to allocate the fleet in a systematic way.Claudio Benevenuto de Campos Lima Pedro Esteves Aranha Jose Francisco Tebaldi de Castro Gilson Brito Alves Lima Augusto Borella Hougaz Felipe de Souza Terra 2018Petroleum Science2018,15,2:1
20Epidnral analgesia and active management of labor:effects on length of labor and mode of delivery显示文摘Rogers R Gilson G Kammerer Douk D 1999Obstet Gynecol1999,93,6:1
返回顶部 每页显示:
共44页 首页 上一页 第1页 下一页 末页 /44 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费