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| 1 | Caveolin‐1 is a novel regulator of K‐RAS ‐dependent migration in colon carcinogenesis显示文摘 | Upal K. Basu Roy Rebecca S. Henkhaus Fotios Loupakis Chiara Cremolini Eugene W. Gerner Natalia A. Ignatenko | 2013 | Int J Cancer2013，，1： | 2 |
| 2 | Prevalence of autoantibodies and the risk of autoimmune thyroid disease in children with chronic hepatitis C virus infection treated with interferon-α显示文摘AIM: To evaluate the prevalence of autoantibodies in chronic hepatitis C virus (HCV)-infected children focusing on thyroid autoimmunity. METHODS: We investigated the prevalence of auto- antibodies in 123 chronic HCV-infected children before, during and after monotherapy with interferon-alpha (IFN-α) or combined treatment with interferon-α or peginterferon-α and ribavirin. Besides antibodies against smooth muscle (SMA), nuclei (ANA), and liver/kidney microsomes (LKM), the incidence of anti- thyroid peroxidase antibodies as well as thyroid function parameters (TSH, FT3 and FT4) were determined. RESULTS: We found that 8% of children had autoantibodies before treatment. During treatment, 18% of children were found positive for at least one autoantibody; 15.5% of children developed pathologic thyroid values during IFN-α treatment compared to only one child before therapy. Six children had to be substituted while developing laboratory signs of hypothyroidism. CONCLUSION: Our data indicate a strong correlation between interferon-α treatment and autoimmune phenomena, notably the emergence of thyroid antibodies. The fact that some children required hormone replacement underlines the need of close monitoring in particularly those who respond to therapy and have to be treated for more than 6 mo. | Stephan Gehring Ulrike Kullmer Sabine Koeppelmann Patrick Gerner Philip Wintermeyer Stefan Wirth | 2006 | World Journal of Gastroenterology2006，12，36： | 2 |
| 3 | ERK is sequentially activated in neurons, microglia, and astroeytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model显示文摘 | Zhuang ZY Gerner P Woof CJ | 2005 | Pain2005，114，12： | 1 |
| 4 | Mutations in the basic core promotor and the precore region of hepatitis B virus and their selection in children with fulminant and chronic hepatitis B显示文摘 | Friedt M Gerner P Lausch E | 1999 | Hepatology1999，29，4： | 1 |
| 5 | Polyamine-dependent gene expression显示文摘 | CHILDS A C MEHTA D J GERNER E W | 2003 | Cellular and Molecular Life Sciences2003，60，7： | 1 |
| 6 | Polyamines are oncometab-olites that regulate the LIN28/let-7 pathway in colorectalcancer cells显示文摘 | Paz EA LaFleur B Gerner EW | 2014 | Mol Carcinog2014，531，： | 1 |
| 7 | Combination of 5-fluorouracil and Nl , N11- diethylnorspermine markedly activates spermidine/spermine N l-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells显示文摘 | CHOI W GERNER E W RAMDAS L | 2005 | J Biol Chem2005，280，5： | 1 |
| 8 | Ascending myelopathy in the early stage of spinal cord injury显示文摘 | Aito S El Masry WS Gerner H J | 1999 | Spinal Cord1999，37，9： | 1 |
| 9 | Pre-B cell colony enhancing factor/NAMPT/visfatin in in- flammation and obesity-related disorders 显示文摘 | MOSCHEN A R GERNER R R TILG H | 2010 | Curt Pharm Des2010，16，： | 1 |
| 10 | The epidemi- ology of human listeriosis 显示文摘 | SWAMINATHAN B GERNER - SMIDT P | 2007 | Microbes Infect2007，9，10： | 1 |
| 11 | The efficacy of wrist protectors in preventing snowboarding injuries 显示文摘 | Rcnning R Rcnning I Gerner T | 2001 | Am J Sports Med2001，5，： | 1 |
| 12 | Follow-up and education of employees exposed to a patient with HIV antibodies and massive bleeding显示文摘 | Gerner H M Ivey F D Lane T W | 1989 | Am J Infec Control1989，17，： | 1 |
| 13 | Additives to local anesthetics for peripheral nerve blocks or local anesthesia:a review of the literature显示文摘 | Opperer M Gerner P Memtsoudis SG | 2015 | Pain Manag2015，5，2： | 1 |
| 14 | Cell cycle-specific activity of type I and type II cyclic AMP protein kinases in Chinese hamster ovary cell显示文摘 | Costa M Gerner EW Russell DH | 1976 | J Biol Chem1976，251，11： | 1 |
| 15 | Developing convective heat transfer in deep rectangular microchannels 显示文摘 | HARMS T M KAZMIERZAK M GERNER F M | 1999 | Int J Heat and Fluid Flow1999，20，2： | 1 |
| 16 | Pre-B cell colony en-hancing factor/NAMPT/visfatin in inflammation andobesity-related disorders显示文摘 | Moschen A R Gerner R Tilg H | 2010 | Current Pharmaceutical2010，16，17： | 1 |
| 17 | Destructive osteoblastoma of the cervical spine with complete neurologic recovery显示文摘 | Schneider M Sabo D Gerner HJ | | 0，，： | 1 |
| 18 | Follow - up and education of emplogees exposed to a patient with HIV antibodies and massive bleeding 显示文摘 | Gerner HM Ivey FD Lane TW | 1989 | Am J Infect Control1989，17，： | 1 |
| 19 | Survival and cell kinetics effects of adriamycin on mammalian cells显示文摘 | BARRANCO S C GERNER E W BURK K H | 1973 | Cancer Res1973，33，： | 1 |
| 20 | Proteome analysis of nuclear matrix proteins during apoptotic chromatin condensation显示文摘 | Gerner C Gotzmann J Frohwein U | 2002 | Cell Death Differ2002，9，6： | 1 |
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