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1最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL 2014神经病学与神经康复学杂志2014,11,3:31
2Circadian distribution of ischemic attacks and ischemia-related ventricular arrhythemias in patients with variant angina显示文摘Lanza GA Patti G Pasceri V 1999Cardiologia1999,40,10:2
3WONCA研究论文摘要汇编——罕见癌症患者转诊前的全科医生问诊:研究报告数据显示文摘——罕见癌症患者转诊前的全科医生问诊:研究报告数据【摘要】背景部分癌症患者在初级医疗中经历多次诊断前问诊,导致专科医生调查和诊断延后。罕见癌症患者更有可能面临这种情况,但是缺乏具体证据。目的探讨罕见癌症患者接受全科医生重复问诊的频率和预测因子。Mendonca SC Abel GA Lyratzopoulos G 本刊编辑部 2016中国全科医学2016,19,12:2
4Plamid determined AmpC type beta lactamases 显示文摘Philippon A Arlet G Jacoby GA 2002Antimierob Agents Chemother2002,46,5:1
5Congenital choledochal cyst:video-guided laparoscopic treatment显示文摘 Cerofolini A Rebonato M Bergamaschi G Ferrari C Chiappetta A 1995Surg Laparosc Endosc1995,5,:1
6Characterization of endothelin-binding sites in human skin and their regulation in primary Raynaud's phenomenon and systemic sclerosis显示文摘Knock GA Tereghi G Bunker CB 1993J Invest Dermatol1993,101,1:1
7Increased plasma leptin/fat ration in patients with chronic renal failure:a cause of malnutrition显示文摘Young GA Woodrow G Kendall S 1997Nephrol Dial Transplant1997,12,11:1
8Plasmid-determined AmpC- type beta-lactamases显示文摘Philippon A Arlet G Jacoby GA 2002Antimierob Agents Chemother2002,46,1:1
9Mutations in PLCE1 are a major cause of isolated diffuse mesangial sclerosis (IDMS) 显示文摘Gbadegesin R Hinkes B G Hoskins B E Vlangos C N Heerin ga S F Liu J 2008Nephrol Dial Transplant2008,23,:1
10Hepatic growths mimicking adrenal tumors显示文摘Del Gaudio A Solidoro G Del Gaudio GA 1998Hepatogastroenterology1998,45,23:1
11Circulating endothelial progenitor cells predict coronary artery disease severity显示文摘Kunz GA Liang G Cuculi F 2006Am Heart J2006,152,1:1
12Assessment of uterine cavity by hysteroscopy in assisted reproduction progamme and its itffluence on pregnancy outcome显示文摘Rama Raju GA Shashi Kumarei G Krishna KM 2006Arch Gynecol Obstet2006,274,1:1
13Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis 显示文摘Koopman G Reutelingsperger CP Kuijten GA 1994Blood1994,84,:1
14Plasmid-determined AmpC-tye β-lactmamses 显示文摘Philippon A Arlet G Jacoby GA 2002Antimicrob Agents Clemother2002,46,1:1
15The red wine antioxidant res- veratrol protects isolated rat hearts from ischemia reperfusion injury 显示文摘Ray PS Maulik G Cordis GA 1999Free Radic Biol Med1999,27,12:1
16Ambroxol : a multifaceted molecule with additional therapeutic potentials in respiratory disor- ders of childhood 显示文摘Paleari D Rossi GA Nicolini G 2011Expert Opinion on Drug Discovery2011,6,:1
17Pretreatment or resuscitation with a lipid emulsion Shifts the dose-response to bupivacaine-induced asystole in rats 显示文摘Weinberg G Vade Boncouer T Ramaraju GA 1998Anesthesiology1998,88,:1
18Paediatricspinal Langerhans cell histiocytosis requiring corpectomy and fusion at C7 and at Th8-Th9 levels 显示文摘Talamonti G D'Aliberti GA Debernardi A 2012BMJ Case Rep2012,,:1
19Tackling antibiotic resistance显示文摘Bush K Courvalin P Dantas G Davies J Eisenstein B Huovinen P Jacoby GA Kishony R Kreiswirth BN Kutter E Lerner SA Levy S Lewis K Lomovskaya O Miller JH Mobashery S Piddock LJ Projan S Thomas CM Tomasz A Tulkens PM Walsh TR Watson JD Witkowski J Witte W Wr 0,,:1
20Diagnosis of root avulsion in traumatic brachial plexus injuries: value of computer- ized tomography myelography and magnetic resonance imaging显示文摘Carvalho GA Nikkhah G Matthies CM 1997J Neurosurg1997,86,1:1
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