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| 1 | Systematic review of novel ablative methods in locally advanced pancreatic cancer显示文摘Unresectable locally advanced pancreatic cancer with or without metastatic disease is associated with a very poor prognosis.Current standard therapy is limited to chemotherapy or chemoradiotherapy.Few regimens have been shown to have a substantial survival advantage and novel treatment strategies are urgently needed.Thermal and laser based ablative techniques are widely used in many solid organ malignancies.Initial studies in the pancreas were associated with significant morbidity and mortality,which limited widespread adoption.Modifications to the various applications,in particular combining the techniques with high quality imaging such as computed tomography and intraoperative or endoscopic ultrasound has enabled real time treatment monitoring and significant improvements in safety.We conducted a systematic review of the litera-ture up to October 2013.Initial studies suggest that ablative therapies may confer an additional survival benefit over best supportive care but randomised studies are required to validate these findings. | Margaret G Keane Konstantinos Bramis Stephen P Pereira Giuseppe K Fusai | 2014 | World Journal of Gastroenterology2014，20，9： | 30 |
| 2 | Small for size syndrome following living donor and split liver transplantation显示文摘The field of liver transplantation is limited by the availability of donor organs. The use of living donor and split cadaveric grafts is one potential method of expanding the donor pool. However, primary graft dysfunction can result from the use of partial livers despite the absence of other causes such as vascular obstruction or sepsis. This increasingly recognised phenomenon is termed 'Small-for-size syndrome' (SFSS). Studies in animal models and humans have suggested portal hyperperfusion of the graft combined with poor venous outflow and reduced arterial flow might cause sinusoidal congestion and endothelial dysfunction. Graft related factors such as graft to recipient body weight ratio < 0.8, impaired venous outflow, steatosis > 30% and pro- longed warm/cold ischemia time are positively predictive of SFSS. Donor related factors include deranged liver function tests and prolonged intensive care unit stay greater than five days. Child-Pugh grade C recipients are at relatively greater risk of developing SFSS. Surgi- cal approaches to prevent SFSS fall into two categories: those targeting portal hyperperfusion by reducing inflow to the graft, including splenic artery modulation and portacaval shunts; and those aiming to relieve paren-chymal congestion. This review aims to examine thecontroversial diagnosis of SFSS, including current strate-gies to predict and prevent its occurrence. We will also consider whether such interventions could jeopardize the graft by compromising regeneration. | Hector Daniel Gonzalez Sophia Cashman Giuseppe K Fusai | 2010 | World Journal of Gastrointestinal Surgery2010，2，12： | 13 |
| 3 | Is there a role for arterial reconstruction in surgery for pancreatic cancer?显示文摘Surgery remains the only potentially curative treatment for patients with pancreatic cancer. Locally advanced pancreatic cancer with vascular involvement remains a surgical challenge because high perioperative risk and the uncertainty of a survival benefit. Whilst portal vein resection has started to gather momentum because the perioperative morbidity and long term survival is comparable to standard pancreatectomy, there isn't yet a consensus on arterial resections. There have been various reports and case series of arterial resections in pancreatic cancer, with mixed survival results. Mollberg et al have appraised the heterogeneous published literature available on arterial resection in pancreatic cancer in an attempt to compare this to standard pancreatectomy. In this article, we discuss the results of this systematic review and meta-analysis, and the limitations associated with analysing results from heterogenous data. We have outlined the important features in surgery for pancreatic cancer and specifically to arterial resections, and compared arterial resections to the published literature on venous resections. | Reena Ravikumar David Holroyd Giuseppe Fusai | 2013 | World Journal of Gastrointestinal Surgery2013，5，3： | 5 |
| 4 | Impact of postoperative intravenous fluid administration on complications following elective hepato-pancreato-biliary surgery显示文摘Background: The impact of perioperative intravenous fluid administration on surgical outcomes has been documented in literature, but not specifically studied in the context of hepato-pancreato-biliary(HPB) surgery. This study aimed to investigate the impact of postoperative intravenous fluid administration on intensive care unit(ICU), in this subgroup of patients. Methods: A single-center retrospective cohort of 241 HPB patients was assessed, focusing on intravenous fluid administration in ICU, during the first 24 h. Intravenous fluid variables were compared to hospital stay and postoperative complications. Data were assessed using Spearman's correlation test for bivariate correlations and logistic regression for multivariate analysis. Results: The median volume of intravenous fluid administered in the first 24 h postoperatively was 4380 mL, of which 2200 mL was crystalloid, 1500 mL colloid and 680 mL 'other' fluid. Patients with one or more complications had a higher median total intravenous fluid input(4790 vs. 4300 mL), higher colloid volume(20 0 0 vs. 150 0 mL), lower urine output(1595 vs. 1900 mL) and greater overall fluid balance( + 3040 vs. + 2553 mL) than those without complications. There were correlations between total intravenous fluid volume administered( r = 0.278, P < 0.001), intravenous colloid input( r = 0.278, P < 0.001), urine output( r =-0.295, P < 0.001), positive fluid balance( r = 0.344, P < 0.001) and length of hospital stay. Logistic regression model was constructed to predict the occurrence of one or more complications; total intravenous fluid volume and overall fluid balance were both independent significant predictors(OR = 2.463, P = 0.007; OR = 1.001, P = 0.011; respectively). Conclusions: Administration of high volumes of intravenous fluids in the first 24 hours post-HPB surgery, along with higher positive fluid balance is associated with a higher rate of complications and longer hospital stay. Moreover, lower urine output is associated with longer hospital stay. Whether these are the cause of complications or the result of them remains unclear. | Daniel Martin Panagis M.Lykoudis Gabriel Jones David Highton Alan Shaw Sarah James Qiang Wei Giuseppe Fusai | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，5： | 2 |
| 5 | Somatostatin analogues for pancreatic surgery显示文摘 | Gurusamy KS Koti R Fusai G | | 0，，： | 1 |
| 6 | Management of colorectal liver metastases显示文摘 | Fusai C Davidson BR | 2003 | Colorectal Dis2003，5，1： | 1 |
| 7 | Ultrastructural changes in parasites induced by nanoparticle-bound pentamidine in a Leishmania major/mouse model显示文摘 | Fusai T Boulard Ydurand R | | 0，，04： | 1 |
| 8 | Management of colorectal liver metastases显示文摘 | Fusai G Davidson BR | 2003 | Colorectal Dis2003，5，1： | 1 |
| 9 | Early versus delayed laparoscopic cholecystectomy for biliary colic显示文摘 | Gurusamy KS Samraj K Fusai G | 2008 | Cochrane Database Syst Bey2008，，00： | 1 |
| 10 | Analysis of quadrature methods for pricing discrete barrier options显示文摘 | Fusai G Recchioni M C | 2007 | Journal of Economic Dynamics&Control2007，31，3： | 1 |
| 11 | Risk factors associated with early hepatic artery thrombosis after orthotopic liver transplantation:univariable and multivariable analysis显示文摘 | Warner P Fusai G Glantzounis GK | 2011 | Transpl Int2011，24，： | 1 |
| 12 | Analysis of quadrature methods for pricing discrete barrier options显示文摘 | Fusai G Recchioni M C | 2007 | Journal of Economic Dynamics & Control2007，31，3： | 1 |
| 13 | Management of colorectal liver metastases 显示文摘 | Fusai G Davidson BR | 2003 | Colorectal Dis2003，5，： | 1 |
| 14 | Management of colorectal liver metastases显示文摘 | Fusai G Davidson BR | | 0，，01： | 1 |
| 15 | Pricing discretely monitored Asian options under Levy processes显示文摘 | Fusai G Meucei A | 2008 | Journal of Banking & Finance2008，32，： | 1 |
| 16 | N-Acetylcysteine ameliorates the late phase of liver ischaemia/reperfusion injury in the rabbit with hepatic steatosis显示文摘 | Fusai G Glantzounis G K Hafez T | 2005 | Clin Sci2005，109，： | 1 |
| 17 | Management of colorectal liver metastases显示文摘 | Fusai G Davidson BR | 2003 | Colorectal Dis2003，5，1： | 1 |
| 18 | Compliance Measurement of Lower Esophageal Sphincter and Esophageal Body in Achalasia and Gastroesophageal Reflux Disease显示文摘 | Andrew D. Jenkinson S. Mark Scott Etsuro Yazaki Giuseppe Fusai Sharon M. Walker Sritharan S. Kadirkamanathan David F. Evans | 2001 | Digestive Diseases and Sciences2001，，9： | 1 |
| 19 | Pricing Discretely Monitored Asian Options under Levy Processes显示文摘 | Fusai G Meucci A | 2008 | Journal of Banking and Finance2008，32，10： | 1 |
| 20 | Incidence and risk factorsfor the development of prolonged and severe intrahepatic cholestasis after liver transplantation 显示文摘 | Fusai G Dhaliwal P Roland N | 2006 | Liver Transpl2006，12，11： | 1 |
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