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| 1 | Chromosome-scale genome assembly provides insights into the evolution and flavor synthesis of passion fruit (Passiflora edulis Sims)显示文摘Passion fruit(Passiflora edulis Sims)is an economically valuable fruit that is cultivated in tropical and subtropical regions of the world.Here,we report an~1341.7Mb chromosome-scale genome assembly of passion fruit,with 98.91%(~1327.18Mb)of the assembly assigned to nine pseudochromosomes.The genome includes 23,171 protein-coding genes,and most of the assembled sequences are repetitive sequences,with long-terminal repeats(LTRs)being the most abundant.Phylogenetic analysis revealed that passion fruit diverged after Brassicaceae and before Euphorbiaceae.Ks analysis showed that two whole-genome duplication events occurred in passion fruit at 65 MYA and 12 MYA,which may have contributed to its large genome size.An integrated analysis of genomic,transcriptomic,and metabolomic data showed that‘alpha-linolenic acid metabolism’,‘metabolic pathways’,and‘secondary metabolic pathways’were the main pathways involved in the synthesis of important volatile organic compounds(VOCs)in passion fruit,and this analysis identified some candidate genes,including GDP-fucose Transporter 1-like,Tetratricopeptide repeat protein 33,protein NETWORKED 4B isoform X1,and Golgin Subfamily A member 6-like protein 22.In addition,we identified 13 important gene families in fatty acid pathways and eight important gene families in terpene pathways.Gene family analysis showed that the ACX,ADH,ALDH,and HPL gene families,especially ACX13/14/15/20,ADH13/26/33,ALDH1/4/21,and HPL4/6,were the key genes for ester synthesis,while the TPS gene family,especially PeTPS2/3/4/24,was the key gene family for terpene synthesis.This work provides insights into genome evolution and flavor trait biology and offers valuable resources for the improved cultivation of passion fruit. | Zhiqiang Xia Dongmei Huang Shengkui Zhang Wenquan Wang Funing Ma Bin Wu Yi Xu Bingqiang Xu Di Chen Meiling Zou Huanyu Xu Xincheng Zhou Rulin Zhan Shun Song | 2021 | Horticulture Research2021，8，1： | 15 |
| 2 | Social Isolation in Male Rats During Adolescence Inhibits the Wnt/β-Catenin Pathway in the Prefrontal Cortex and Enhances Anxiety and Cocaine-Induced Plasticity in Adulthood显示文摘In adult animals,it is well established that stress has a proactive effect on psychostimulant responses.However,whether only a short period of stress during adolescence can also affect cocaine responses later in life and what mechanisms are involved are unknown.Here,we showed that 5 days of social isolation during rat adolescence had a long-term impact on anxiety-like behaviors,cocaine-induced conditioned place preference,and the expression of sensitization during adulthood.At the molecular level,social isolation decreased the activity of the Wnt/β-catenin pathway in the prefrontal cortex(PFC).Furthermore,after the expression of cocaine sensitization,isolated rats showed an increase in this pathway in the nucleus accumbens.Together,these findings suggest that,adolescent social isolation by altering the Wnt/β-catenin pathway in the developing PFC might increase the cocaine responses during adulthood,introducing this pathway as a novel neuroadaptation in the cortical-accumbens connection that may mediate a stress-induced increase in vulnerability to drugs. | Santiago Cuesta Alejandrina Funes Alejandra M.Pacchioni | 2020 | Neuroscience Bulletin2020，36，6： | 5 |
| 3 | 古巴的有机农业运动显示文摘在历史大背景和古巴政府发起的现代改革的前提下,古巴意识到替代传统农业模式的必要。20世纪90年代,古巴有机农业协会的形成小组(ACAO)在推动古巴有机农业方面发挥了巨大作用,众多研究中心多年的研究成果与农民积累的大量经验也为有机农业的发展奠定基础。古巴在有机肥料、土壤保持、作物与畜禽管理等方面均取得重要成果,它推行的全国都市农业计划、小型水稻生产普及等成功经验,使古巴的有机农业转变堪称典范。如今的古巴已完成替代依赖于投入的农业模式的目标,在未来要面临的挑战是要建立更加复杂的生态农业体系。 | Fernando Funes 黄小莉(译) | 2010 | 开放时代2010，，4： | 3 |
| 4 | Hypothetical Commercialization of Biotech Soybeans in China: Impacts on Domestic Markets and International Trade显示文摘 | Francis Tuan James Hansen Agapi Somwaru Mary Marchant Nicholas Kalaitzandonakes Funing Zhong | 2010 | Journal of Life Sciences2010，4，3： | 3 |
| 5 | The KiSS-1 receptor GPR54 is essential for the development of the murine reproductive system显示文摘 | Sandrine Funes Joseph A Hedrick Galya Vassileva Lisa Markowitz Susan Abbondanzo Andrei Golovko Shijun Yang Frederick J Monsma Eric L Gustafson | 2003 | Biochemical and Biophysical Research Communications2003，，： | 2 |
| 6 | Efficient extraction and stripping of Nd(Ⅲ),Eu(Ⅲ) and Er(Ⅲ) by membrane dispersion micro-extractors显示文摘The extraction of low concentration rare earth elements at high phase ratio was investigated. The traditional extraction set-up, such as mixer-settler, have drawbacks of easy emulsification, difficult separation and low efficiency if operated at the above condition. Membrane dispersion micro-extractor,owing to its well-dispersed, high surface-to-volume ratio and fast mass transfer rate, was employed in our work. Nd(Ⅲ),Eu(Ⅲ),Er(Ⅲ) were chosen to represent light, medium,heavy rare earth elements(REEs). The extraction process of REEs with 2-ethylhexyl phosphoric acid-2-ethylhexyl ester(P507) was investigated by membrane dispersion micro-extractors. Firstly, the extraction equilibrium of these three elements was explored in the stirred conical flasks, and it is indicated that the extraction efficiencies can be 0.95, 0.97 and 0.98, respectively within 40 min at phase ratio of 100:1. Then the effects of operational conditions such as the residence time, organic and aqueous flow rates on extraction efficiency were also explored in micro-extractors. The results indicate that the efficiency decreases and then increases if increasing aqueous phase flow rate, residence time and droplets' diameter are the key factors of this process. Increasing the phase ratio reduces the extraction efficiency significantly. When the REEs solution has an initial pH of 4.00, the flow rates of continuous and dispersed phase are 40 and 1.6 mL/min,respectively, and 90 mg/L Nd(Ⅲ), Eu(Ⅲ) and Er(Ⅲ) is extracted by 1 mol/L P507 at the out-let length of8 m. The extraction efficiencies are 0.978,0.983 and 0.991, respectively. Finally the stripping process was also studied with the micro-extractor. The stripping efficiencies of Nd(Ⅲ), Eu(Ⅲ) and Er(Ⅲ) can reach0.99, 0.96 and 0.91, respectively when the out-let length is 8 m and the concentration of hydrochloric acid is 1 mol/L. The developed approach offers a novel and simple strategy on the fast extraction and enrichment of low concentration rare earth elements from waste water. | Zhuo Chen Jianhong Xu Funing Sang Yundong Wang | 2018 | Journal of Rare Earths2018，36，8： | 2 |
| 7 | 磁力减振器减振特性的研究显示文摘使用传统减振器是减振和降噪的有效方法之一,但它有两个缺点:一是安装工作量大;二是只在有限的频率和温度范围内才能表现出高减振性能。为了克服这些缺点,我们开发了一种新型减振器─—磁力减振器(MVD)。通过应用磁力,磁力减振器不仅具有良好的可加工性,而且减振性能得到提高。 | Naoto MI FUNE 杨兵 | 1998 | 国外内燃机车1998，，5： | 2 |
| 8 | Application of pulsed light to patulin reduction in Mcllvaine buffer and apple products显示文摘 | FUNES G J GOMEZ P L RESNIK S L | 2013 | Food Control2013，30，2： | 1 |
| 9 | Independent geneduplications of the YidC/Oxa/Alb3 family enabled a specialized cotranslational function显示文摘 | Funes S Hasona A Bauerschmitt H | 2009 | Proceedings of the National Academy of Sciences of the United States of America2009，106，16： | 1 |
| 10 | Novel Stepper Motor Controller Based on FPGA Hardware Implemen- tation显示文摘 | Carrica D Funes M A Gonzalez S A | 2003 | IEEE/ASME Transactions on Mechatron- ics2003，8，1： | 1 |
| 11 | The Oxa2 protein of Neurospora crassa plays a critical role in the biogenesis of cytochrome oxidase and defines a ubiquitous subbranch of the Oxal/YidC/Alb3 protein family显示文摘 | Funes S Nargang FE Neupert W | 2004 | Molecular Biology of the Cell2004，15，4： | 1 |
| 12 | Detection of foxp3 ^+ cells on biopsies of kidney transplants with early acute rejection显示文摘 | Martin L Funes de la Vega M Bocrie O | 2007 | Transplant Proc2007，39，8： | 1 |
| 13 | Isolation and characterization of ten microsatellite loci for senegal sole (Solea senegalensis Kaup)显示文摘 | FUNES V ZUASTI E CATANESE G | 2004 | Molecular Ecology Notes2004，4，3： | 1 |
| 14 | The KiSS-1 receptor GPR54 is essential for the development of lhe murin reproductive system显示文摘 | FUNES S HEDRICK JA VASSILEVA G | 2003 | Biochem Biophys Res Commun2003，312，4： | 1 |
| 15 | Effect of release rate and enantiomeric composition on response to pheromones of Megaplatypus mutatus (Chapuis) in poplar plantations of Argentina and Italy显示文摘 | Hernán Funes Eduardo Zerba Paola Gonzalez-Audino | 2013 | Bulletin of Entomological Research2013，，： | 1 |
| 16 | The KISS-1 receptor GPR54 is essential for the development of the murine reproductive system 显示文摘 | FUNES S HEDRICK J VASSILEVA G | 2003 | Biochemical and Biophysical Research Communications2003，312，4： | 1 |
| 17 | Application of pulsed light to patulin reduction in MeIlvaine buffer and apple products显示文摘 | Funes G J Gomez PL Rcsnik SL | 2013 | Food Control2013，30，2： | 1 |
| 18 | Quality indicators and specifications for key processes in clinical laboratories: a preliminary experience显示文摘 | Kirchner MJ Funes VA Adzet CB | 2007 | Clin Chem Lab Med2007，45，5： | 1 |
| 19 | Current control for high-dynamic high-power multiphase Buck converters 显示文摘 | RETEGUI R G BENEDET'FI M FUNES M | 2012 | IEEE Transactions on Power Electronics2012，27，2： | 1 |
| 20 | Income vs price subsidy:policy options to help the urban poor facing food price surge显示文摘 | HUANG C FUNING Z JUN H | 2013 | China Agricultural Economic Review2013，5，1： | 1 |
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