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| 1 | 用仿生自组装法制备的新型生物复合材料及表征显示文摘通过仿生自组装法在室温下制备了纳米碳酸化羟基磷灰石/胶原(nCHAC)复合材料,并采用X射线衍射(XRD)、热分析(TGA)和透射电镜(TEM)进行了观察和分析.结果表明,该材料具有与天然骨相同的纳米尺度和胶原蛋白无机相,含有(2.8~14.7)w%的碳酸化HA成分;其显微结构是矿化的胶原纤维束,类似于天然骨的分级结构.揭示了碳酸化HA和胶原含量不同的复合材料中,具有微小差别的自组装单元.碳酸的百分含量影响矿物的晶体尺寸和胶原纤维的组装.因此,nCHAC复合材料是有前途的硬组织修复用材料,其所具有的特殊性能要归功于生物仿生制备出的nCHAC材料有与天然骨类似的成分和类似的微观结构. | 徐国富 牟申周 廖素三 Fumio Watari | 2006 | 稀有金属快报2006，25，5： | 2 |
| 2 | Carbon nanotubes functionalized with fibroblast growth factor accelerate proliferation of bone marrow-derived stromal cells and bone formation显示文摘 | Eri Hirata Cécilia Ménard-Moyon Enrica Venturelli Hiroko Takita Fumio Watari Alberto Bianco Atsuro Yokoyama | 2013 | Nanotechnology2013，，43： | 1 |
| 3 | Biocom- patibility and osteogenesis of refractory metal im- plants, titanium, hafnium, niobium, tantalum and rhenium 显示文摘 | Hironobu Matsuno Atsuro Yokoyama Fumio Watari | 2001 | Biomaterials2001，22，11： | 1 |
| 4 | Oxidation of multiwalled carbon nanotubes by nitric acid显示文摘 | IOSIF DANIEL ROSCA FUMIO WATARI MOTOHIRO UO TSUKASA AKASAKA | 2005 | Carbon2005，43，： | 1 |
| 5 | Biocompatibility of materials and development to functionally graded implant for hio-medieal application 显示文摘 | Fumio Watari Atsuro Yokoyama Mamoru Omori | 2004 | Composites Science and Technology2004，64，6： | 1 |
| 6 | Effects of Ti ions and particles on neutrophil function and morphology显示文摘 | Ryuichiro Kumazawa Fumio Watari Noriyuki Takashi Yukihiro Tanimura Motohiro Uo Yasunori Totsuka | 2002 | Biomaterials2002，，17： | 1 |
| 7 | Oxidation of multiwalled carbon nanotubes by nitric acid显示文摘 | Iosif Daniel Rosca Fumio Watari Motohiro Uo Tsukasa Akasaka | 2005 | Carbon2005，，15： | 1 |
| 8 | Biocompatibility and osteogenesis of refractory metal implants, titanium, hafnium, niobium, tantalum and rhenium显示文摘 | Hironobu Matsuno Atsuro Yokoyama Fumio Watari Motohiro Uo Takao Kawasaki | 2001 | Biomaterials2001，，11： | 1 |
| 9 | The use of carbon nanotubes to induce osteogenic differentiation of human adipose-derived MSCs in vitro and ectopic bone formation in vivo显示文摘 | Xiaoming Li Haifeng Liu Xufeng Niu Bo Yu Yubo Fan Qingling Feng Fu-zhai Cui Fumio Watari | 2012 | Biomaterials2012，，19： | 1 |
| 10 | Carbon Nanotube Coating on Titanium Substrate Modified with TiO_2 Nanotubes显示文摘A combination of carbon nanotubes (CNTs) and titanium (Ti) modified with TiO2 nanotubes (TiO2 NTs) was fulfilled with the aim of improving bioactivity of Ti implant.First,well-ordered TiO2 NTs were prepared by the electrochemical anodization of Ti in an ethylene glycol electrolyte containing 1 wt% NH4F and 10 wt% H2O at 20 V for 50 min,followed by annealing.Then,the carboxylated CNTs were coated onto the TiO2 NTs using electrophoretic deposition (EPD) technique.The growth of hydroxyapatite (HA) on the samples was investigated by soaking them in simulated body fluid (SBF).The result showed the CNTs-coated Ti with the modification of TiO2 NTs (CNTs-TiO2 NTs) was more efficient to induce HA formation than the CNTs-coated smooth Ti (CNTs-Ti).The vitro cell response was evaluated using osteoblast cells (MC3T3-E1).The good cell proliferation and strong cell adhesion could be obtained on the CNTs-TiO2 NTs.These results indicated that CNT coating on the Ti modified with TiO2 NTs could be potentially useful for the periodontal ligament combination on dental implants. | 白玉 PARK Ilsong BAE Taesung KIM Kyounga WATARI Fumio UO Motohiro LEE Minho | 2011 | Journal of Wuhan University of Technology(Materials Science)2011，26，5： | 0 |
| 11 | Fiber-reinforced scaffolds in soft tissue engineering显示文摘Soft tissue engineering has been developed as a new strategy for repairing damaged or diseased soft tissues and organs to overcome the limitations of current therapies.Since most of soft tissues in the human body are usually supported by collagen fibers to form a three-dimensional microstructure,fiber-reinforced scaffolds have the advantage to mimic the structure,mechanical and biological environment of natural soft tissues,which benefits for their regeneration and remodeling.This article reviews and discusses the latest research advances on design and manufacture of novel fiber-reinforced scaffolds for soft tissue repair and how fiber addition affects their structural characteristics,mechanical strength and biological activities in vitro and in vivo.In general,the concept of fiber-reinforced scaffolds with adjustable microstructures,mechanical properties and degradation rates can provide an effective platform and promising method for developing satisfactory biomechanically functional implantations for soft tissue engineering or regenerative medicine. | Baoqing Pei Wei Wang Yubo Fan Xiumei Wang Fumio Watari Xiaoming Li | 2017 | Regenerative Biomaterials2017，4，4： | 0 |
| 12 | 碳酸化羟基磷灰石/胶原(nCHAC)生物复合材料的室温制备及表征显示文摘通过仿生自组装法在室温下制备了纳米碳酸化羟基磷灰石/胶原(nCHAC)复合材料,并借助X射线衍射(XRD)分析、热分析(TGA)和透射电镜(TEM)的观察对其进行了表征,结果表明:(1)该材料具有与天然骨相同的纳米尺度和胶原蛋白无机相,含有2.8%~14.7%(wt)的碳酸成分;(2)显微结构是矿化的胶原纤维束,类似于天然骨的分级结构。揭示了碳酸和胶原含量不同的复合材料中具有微小差别的自组装单元。碳酸的百分含量影响矿物的晶体尺寸和胶原纤维的组装。因此,nCHAC复合材料是有前途的硬组织修复用材料,这要归功于生物仿生制备出的材料具有与天然骨类似的成分和类似的微观结构。 | 徐国富 牟申周 廖素三 Fumio Watari | 2006 | 材料导报2006，20，8： | 0 |
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