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| 1 | A Comparative Analysis of Binary Logistic Regression and Analytical Hierarchy Process for Landslide Susceptibility Assessment in the Dobrovǎt River Basin,Romania显示文摘A correct assessment of the landslide susceptibility component is extremely useful for the diminution of associated potential risks to local economic development, particularly in regard to land use planning and soil conservation. The purpose of the present study was to compare the usefulness of two methods, i.e., binary logistic regression(BLR) and analytical hierarchy process(AHP), for the assessment of landslide susceptibility over a 130-km^2 area in the Moldavian Plateau(eastern Romania) region, where landslides affect large areas and render them unsuitable for agriculture. A large scale inventory mapping of all types of landslides(covering 13.7% of the total area) was performed using orthophoto images, topographical maps, and field surveys. A geographic information system database was created, comprising the nine potential factors considered as most relevant for the landsliding process. Five factors(altitude, slope angle, slope aspect, surface lithology, and land use) were further selected for analysis through the application of a tolerance test and the stepwise filtering procedure of BLR. For each predictor, a corresponding raster layer was built and a dense grid of equally spaced points was generated, with an approximately equal number of points inside and outside the landslide area, in order to extract the values of the predictors from raster layers. Approximately half of the total number of points was used for model computation, while the other half was used for validation. Analytical hierarchy process was employed to derive factor weights, with several pair-wise comparison matrices being tested for this purpose. The class weights, on a scale of 0 to 1, were taken as normalized landslide densities. A comparison of results achieved through these two approaches showed that BLR was better suited for mapping landslide susceptibility, with 82.8% of the landslide area falling into the high and very high susceptibility classes. The susceptibility class separation using standard deviation was superior to either the equal interval or the natural break method. Results from the study area suggest that the statistical model achieved by BLR could be successfully extrapolated to the entire area of the Moldavian Plateau. | Cristian V.PATRICHE Radu PIRNAU Adrian GROZAVU Bogdan ROSCA | 2016 | Pedosphere2016，26，3： | 11 |
| 2 | Circulating microRNAs as non-invasive biomarkers for hepatitis B virus liver fibrosis显示文摘Viruses can alter the expression of host microRNAs(miRNA s) and modulate the immune response during a persistent infection. The dysregulation of host miRNA s by hepatitis B virus(HBV) contributes to the proinflammatory and profibrotic changes within the liver. Multiple studies have documented the differential regulation of intracellular and circulating miRNA s during different stages of HBV infection. Circulating miRNA s found in plasma and/or extracellular vesicles can integrate data on viral-host interactions and on the associated liver injury. Hence, the detection of circulating miRNA s in chronic HBV hepatitis could offer a promising alternative to liver biopsy, as their expression is associated with HBV replication, the progression of liver fibrosis,and the outcome of antiviral treatment. The current review explores the available data on miRNA involvement in HBV pathogenesis with an emphasis on their potential use as biomarkers for liver fibrosis. | Diana Gabriela Iacob Adelina Rosca Simona Maria Ruta | 2020 | World Journal of Gastroenterology2020，26，11： | 4 |
| 3 | Complications of percutaneous transhepatic biliary drainage in patients with dilated and nondilated intrahepatic bile ducts显示文摘 | Andreas Weber Jochen Gaa Bogdan Rosca Peter Born Bruno Neu Roland M. Schmid Christian Prinz | 2008 | European Journal of Radiology2008，，3： | 3 |
| 4 | Physiological effects of amyloid precursor protein and its derivatives on neural stem cell biology and signaling pathways involved显示文摘The pathological implication of amyloid precursor protein(APP)in Alzheimer’s disease has been widely documented due to its involvement in the generation of amyloid-β peptide.However,the physiological functions of APP are still poorly understood.APP is considered a multimodal protein due to its role in a wide variety of processes,both in the embryo and in the adult brain.Specifically,APP seems to play a key role in the proliferation,differentiation and maturation of neural stem cells.In addition,APP can be processed through two canonical processing pathways,generating different functionally active fragments:soluble APP-α,soluble APP-β,amyloid-β peptide and the APP intracellular C-terminal domain.These fragments also appear to modulate various functions in neural stem cells,including the processes of proliferation,neurogenesis,gliogenesis or cell death.However,the molecular mechanisms involved in these effects are still unclear.In this review,we summarize the physiological functions of APP and its main proteolytic derivatives in neural stem cells,as well as the possible signaling pathways that could be implicated in these effects.The knowledge of these functions and signaling pathways involved in the onset or during the development of Alzheimer’s disease is essential to advance the understanding of the pathogenesis of Alzheimer’s disease,and in the search for potential therapeutic targets. | Raquel Coronel Charlotte Palmer Adela Bernabeu-Zornoza María Monteagudo Andreea Rosca Alberto Zambrano Isabel Liste | 2019 | Neural Regeneration Research2019，14，10： | 2 |
| 5 | New coordinative compounds of Mn(Ⅱ) and Cu(Ⅱ) using as ligand N-hydroxy-succinimide显示文摘 | Tutulea M D Rosca I Cretescu I Cailean A Bistricianu I L | | 0，，： | 1 |
| 6 | Cardiac mitochondria in heart failure:decrease in respirasomes and oxidative phosphorylation显示文摘 | Rosca MG Vazquez EJ Kemer J | | 0，，01： | 1 |
| 7 | Flow and heat transfer of Powell-Eyring fluid over a shrinking surface in a parallel free stream 显示文摘 | ROSCA A V POP I | 2014 | International Journal of Heat and Mass Transfer2014，71，： | 1 |
| 8 | Echo-tracking assessment of carotid artery stiffness in patients with aortic valve stenosis显示文摘 | ANTONINI CANTERIN F ROSCA M BELADAN C C | 2009 | Echocardiography2009，26，7： | 1 |
| 9 | Cardiac mitochondria in heart failure:Normal cardiolipin profile and increased threonine phosphorylation of complex Ⅳ显示文摘 | Rosca M Minkler P Hoppel CL | | 0，，11： | 1 |
| 10 | Cardiomyocyte apoptosis in ischemia-reperfusion due to the exogenous oxidants at the time of reperfusion显示文摘 | Rosca A M Matei C Dragan E | 2012 | Cell Biol Int2012，36，12： | 1 |
| 11 | A New Hybrid Method for Image Approximation Using the Easy Path Wavelet Transform 显示文摘 | Plonka G Tenorth S Rosca D | 2012 | IEEE Transactions on Image Processing2012，21，10： | 1 |
| 12 | Left atrial function: pathophysiology, echocardiographic assessment, and clinical applications显示文摘 | Rosca M Lancellotti P Popescu BA | 2011 | Heart2011，97，23： | 1 |
| 13 | Small peptides derived from somatotropin domain-containing proteins inhibit blood andlymphatic endothelial cell proliferation, migration, adhesion and tube formation显示文摘 | Lee E Rosca E V Pandey N B | 2011 | Int J Biochem Cell Biol2011，43，12： | 1 |
| 14 | Anodic passivity of some titanium base alloys in aggressive environments 显示文摘 | POPA M V VASIESCU E DROB P ANGHEL M VASILESCU C ROSCA I M LOPEZ A S | 2002 | Material Corrosion2002，53，1： | 1 |
| 15 | Neurocognitive disorders due to HIV infection显示文摘 | Rosca EC Rosca O Chirileanu RD | 2011 | HIV & AIDS REVIEW2011，10，3： | 1 |
| 16 | Oxidation of multiwalled carbon nanotubes by nitric acid显示文摘 | IOSIF DANIEL ROSCA FUMIO WATARI MOTOHIRO UO TSUKASA AKASAKA | 2005 | Carbon2005，43，： | 1 |
| 17 | A New Hybrid Method for Image Approximation Using the Easy Path Wavelet Transform 显示文摘 | Plonka G Tenorth S Rosca D | 2011 | IEEE Transactions on Image Processing (S1057-7149)2011，20，2： | 1 |
| 18 | Alterations in renal mitochondrial respiration in response to the reactive oxoaldehyde methylglyoxal显示文摘 | Rosca MG Monnier VM Szweda LI | 2002 | Am J Physiol Renal Physiol2002，283，： | 1 |
| 19 | Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation显示文摘 | Rosca MG Mustata TG Kinter MT | 2005 | Am J Physiol Renal Physiol2005，289，2： | 1 |
| 20 | Cardiac mitochondria in heart failure: normal cardiolipin profile and increased threonine phosphorylation of complex IV显示文摘 | Rosca M Minkler P Hoppel CL | 2011 | Biochim Biophys Acta2011，1807，11： | 1 |
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