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| 1 | The Genesis Mechanism of the Mantle Fluid Action and Evolution in the Ore-Forming Process: A Case Study of the Laowangzhai Gold Deposit in Yunnan, China显示文摘Based on petrological studies of the wall rocks, mineralizing rocks, ores and veins from the Laowangzhai gold deposit, it is discovered that along with the development of silication, carbonation and sulfidation, a kind of black opaque ultra-microlite material runs through the spaces between grains, fissures and cleavages. Under observations of the electron microprobe, scanning electronic microscopy and energy spectrum, this kind of ultra-microlite material is confirmed to consist of ultra microcrystalline quartz, silicate, sulfides and carbonates, as well as rutile, scheelite and specularite (magnetite), showing characters of liquation by the analyses of SEM and energy spectrum. The coexistence of immiscibility and precipitating co-crystallization strongly suggests that the mineralizing fluid changed from the melt to the hydrothermal fluid. Combined with the element geochemical researches, it is realized that the ultra-microlite aggregate is the direct relics of the mantle fluid behaving like a melt and supercritical fluid, which goes along with the mantle-derived magma and will escape from the magma body at a proper time. During the alteration process, the nature of the mantle fluid changed and it is mixed with the crustal fluid, which are favorable for mineralization in the Loawangzhai gold deposit. | LIU Xianfan LI Chunhui LU Qiuxia DENG Biping SONG Xiangfeng ZHAO Fufeng CHU Yating XIAO Jixiong YI Liwen HUANG Yupeng | 2012 | Acta Geologica Sinica(English Edition)2012，86，3： | 13 |
| 2 | C^2G^2FSnake: automatic tongue image segmentation utilizing prior knowledge显示文摘Extraction of the tongue body from digital images is essential for automated tongue diagnoses in traditional Chinese medicine. This paper presents a fully automated active contour initial method that utilizes prior knowledge of the tongue shape and its location in tongue images. Then colorspace information is introduced to control curve evolution. Combining the geometrical Snake model with the parameterized GVFSnake model, a novel approach for automatic tongue segmentation: C2G2FSnake (color control-geometric & gradient flow Snake) is proposed. This method increases the curve velocity but decreases the complexity. C2G2FSnake greatly extends practical usage to tongue segmentation, at the same time increasing the precision. Compared with other state-of-the-art works using different images of tongue color, C2G2FSnake realizes automatic tongue segmentation with greatly improved accuracy. | SHI MiaoJing LI GuoZheng LI FuFeng | 2013 | Science China(Information Sciences)2013，56，9： | 12 |
| 3 | Atomistic characterization of binding modes and affinity of peptide inhibitors to amyloid-β protein显示文摘淀粉的蛋白质(A) 的聚集紧被连接到 Alzheimers 疾病的致病。以前的研究发现了那三个肽禁止者(即, KLVFF, VVIA,和 LPFFD ) 能禁止聚集并且减轻导致 A 的 neurotoxicity。然而,有约束力的模式的原子详情和与这些肽禁止者和 A 的有约束力的亲密关系没被披露。这里,使用分子的动力学模拟和分子的力学泊松 Boltzmann 表面区域(MM/PBSA ) 分析,我们在他们和 A 和他们的抑制的分子的基础的顺序特定的相互作用上检验了三个肽禁止者(KLVFF, VVIA,和 LPFFD ) 的效果。所有禁止者展出改变的有约束力的亲密关系到 A, KLVFF 在有最高有约束力的亲密关系,而 LPFFD 有最少。MM/PBSA 分析进一步表明不同的肽禁止者有和 A 的相互作用的不同模式,因而热点绑定残余,和内在的驱动力。在禁止者和 A 之间的特定的基于残余的相互作用为说明不同绑定和抑制机制坚定、比较。这个工作提供基于结构的有约束力的信息让这三个肽禁止者的进一步的修正和优化对聚集提高他们的有约束力、禁止的能力。 | Fufeng LIU Wenjie DU Yan SUN Jie ZHENG Xiaoyan DONG | 2014 | Frontiers of Chemical Science and Engineering2014，8，4： | 4 |
| 4 | Clinical classification and gene mutation of Chinese probands with Charcot-Marie-Tooth disease Analysis of 57 cases显示文摘Charcot-Marie-Tooth(CMT) disease is the most common inherited peripheral neuropathic disorder.CMT is clinically and genetically heterogeneous.To date,27 genes associated with the disease have been cloned.The present study carried out clinical classification according to clinical,electrophysiological and pathological features,conducted inheritance classification according to inheritance patterns,and performed mutation analysis of 13 CMT disease genes(PMP22,CX32,HSPB1,MNF2,MPZ,HSPB8,GDAP1,NFL,EGR2,SIMPLE,RAB7,LMNA,MTMR2) in 57 Chinese probands with CMT.Five cases of AD-CMT1 and 13 cases of sporadic CMT1 were diagnosed as CMT1A;five cases of X-CMT1,one case of X-CMT2 and one case of sporadic CMT1 were diagnosed as CMTX1;four cases of AD-CMT2 were diagnosed as CMT2F;one case of AD-CMT2 and one case of sporadic CMT2 were diagnosed as CMT2A2;one case of AD-CMT2 was diagnosed as CMT2L;one case of AD-CMT2 was diagnosed as CMT2J;one case of AR-CMT1 was diagnosed as CMT4A.Among the 57 CMT probands,seven genotypes were determined among 34 patients,with a detection rate of 59.6%.The results indicated that the clinical classification and inheritance classification are indispensable for selecting potential disease genes for mutation detection,and for efficient molecular diagnosis. | Ruxu Zhang Xiaobo Li Xiaohong Zi Shunxiang Huang Fufeng Zhang Kun Xia Qian Pan Beisha Tang | 2011 | Neural Regeneration Research2011，6，9： | 4 |
| 5 | Special Xenoliths in an Aegirine-Augite Syenite Porphyry in Liuhe,Yunnan,China:Discovery and Implications显示文摘捕虏体的三种特殊类型最近在 Liuhe 在 aegirine 辉石正长岩斑岩被发现了,云南,中国。 Petrographical ,石油化学,电子微探查,和扫描电子显微镜学研究显示那纯方解石 xenocrysts ,忍受石英的黄玉伟晶岩捕虏体源于在他们的迁居期间披风液体排除,并且黑微晶质的充满铁的硅酸盐融化捕虏体是伴随排除的披风液体的抽取的产品并且是,这石英主导地创作了,绿泥石,并且充满铁圆柱并且有典型矿物质的表硅酸盐矿物质例如本国的铁,磷灰石,和锆石。根据体积岩石化学药品和矿物质作文和结晶化国家,微晶质融化捕虏体不进一步是常规 magmatism,和特别本国的铁的存在的产品证明捕虏体是在减小或缺氧的条件下面的披风液体材料。特殊捕虏体的学习在学习区域在不同岩石和阶层中供应 polymetallic 矿化作用的一个重要深过程的 geochemical 背景。 | LIU Xianfan SONG Xiangfeng LU Qiuxia TAO Zhuan LONG Xunrong ZHAO Fufeng | 2009 | Acta Geologica Sinica(English Edition)2009，83，2： | 3 |
| 6 | Isotope Geochronologic and Geochemical Constraints on the Magmatic Associations of the Collisional Orogenic Zone in the West Kunlun Orogen, China显示文摘The Jiajiwaxi pluton in the southern portion of the West Kunlun Range can be divided into two collision–related intrusive rock series, i.e., a gabbro–quartz diorite–granodiorite series that formed at 224±2.0 Ma and a monzonitic granite–syenogranite series that formed at 222±2.0 Ma. The systematic analysis of zircon U-Pb geochronology and bulk geochemistry is used to discuss the magmatic origin(material source and thermal source), tectonic setting, genesis and geotectonic implications of these rocks. The results of this analysis indicate that the parent magma of the first series, representing a transition from I-type to S-type granites, formed from thermally triggered partial melting of deep crustal components in an early island–arc–type igneous complex, similar to an I-type granite, during the continental collision orogenic stage. The parent magma of the second series, corresponding to an S-type granite, formed from the partial melting of forearc accretionary wedge sediments in a subduction zone in the late Palaeozoic–Triassic. During continued collision, the second series magma was emplaced into the first series pluton along a central fault zone in the original island arc region, forming an immiscible puncture-type complex. The deep tectonothermal events associated with the continent–continent collision during the orogenic cycle are constrained by the compositions and origins of the two series. The new information provided by this paper will aid in future research into the dynamic mechanisms affecting magmatic evolution in the West Kunlun orogenic belt. | WANG Chan LIU Hao DENG Jianghong LIU Xianfan ZHAO Fufeng WANG Chun TIAN Xin | 2018 | Acta Geologica Sinica(English Edition)2018，92，2： | 3 |
| 7 | Antidiabetic effect of total flavonoids from Sanguis draxonis in type 2 diabetic rats显示文摘 | Fufeng Chen Hui Xiong Jianxia Wang | 2013 | Journal of Ethnopharmacology2013，149，3： | 1 |
| 8 | Detecting Non-Stationarity for Auscultation Signal of Traditional Chinese Medicine显示文摘The information about the nonstationarity of the aus-cultation signal is utilized in this paper to objectively and auto-matically identify healthy people and patients with qi-deficiency or yin-deficiency. In order to characterize the nonstationarity of the sound signal,the nonlinear cross-prediction method is used to extract features from the signal. A feature selection method based on conditional mutual information maximization criterion (CMIM) is implemented to find an optimal feature set. By means of the support vector machine (SVM) classifier,three common states (healthy,qi-deficiency and yin-deficiency) in traditional Chinese medicine are distinguished using the feature set,and a satisfactory classification accuracy of 80% is achieved in the experiment. In conclusion,the analysis based on the nonstationarity of the sound signal provides an alternative and outstanding approach to the objective auscultation of traditional Chinese medicine (TCM). | YAN Jianjun SHEN Qingwei WANG Yiqin LI Fufeng GUO Rui CHEN Chunfeng SHEN Yong | 2011 | Wuhan University Journal of Natural Sciences2011，16，1： | 1 |
| 9 | New efficient method for dynamic modeling and?simulation of flexible multibody systems moving in?plane显示文摘 | Bao Rong Xiaoting Rui Guoping Wang Fufeng Yang | 2010 | Multibody System Dynamics2010，，2： | 1 |
| 10 | Liquid-liquid equilibria for ternary systems ethanol + heptane + phosphoric-based ion- ic liquids 显示文摘 | CA1 Fufeng XIAO Guomin | 2015 | Fluid Phase Equilibria2015，386，： | 1 |
| 11 | Dynamic modeling and H_∞ independent modal space vibration control of laminate plates显示文摘In this paper, combining the transfer matrix method and the finite element method, the modified finite element transfer matrix method is presented for high efficient dynamic modeling of laminated plates. Then, by constructing the modal filter and the disturbance force observer, and using the feedback and feedforward approaches, the H ∞ independent modal space control strategy is designed for active vibration control of laminate plates subjected to arbitrary, immeasurable disturbance forces. Compared with ordinary dynamic modeling and control methods of laminated plate structures, the proposed method has the low memory requirement, high computational efficiency and robust control performance. Formulations as well as some numerical examples are given to validate the method and the control performance. | RONG Bao RUI XiaoTing WANG GuoPing YANG FuFeng | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，9： | 1 |
| 12 | , Discrete time transfer matrix method for dynamics of multibody system with real-time control显示文摘 | Bao Rong Xiaoting Rui Fufeng Yang | 2010 | Journal of Sound and Vibration2010，329，6： | 1 |
| 13 | A study on the liquid-liquid equilibrium of 1-alkyl-3-methylimid- azolium dialkylphosphate with methanol and dimethyl car- bonate显示文摘 | CAI Fufeng IBRAHIM J J GAO Lijing | 2014 | Fluid Phase Equilibria2014，382，： | 1 |
| 14 | Phosphoric-based ionic liquids as solvents to separate the azeotropic mixture of ethanol and hexane 显示文摘 | CAI Fufeng ZHAO Min WANG Yuan | 2015 | The Journal of Chemical Thermodynamics2015，81，： | 1 |
| 15 | 显示文摘 | FUFeng(付峰) GUOHai-Kang(郭海康) TANGLong(唐龙) etal | | WujiHuaxueXuebao0，，： | 1 |
| 16 | Antidiabeticeffect of total flavonoids from Sanguis draxonis in type 2diabetic rats 显示文摘 | Fufeng Chen Hui Xiong Jianxia Wang | 2013 | Journal of Ethnopharmacology2013，149，3： | 1 |
| 17 | A novel transgenic mouse model of Chinese CharcotMarie-Tooth disease type 2L显示文摘We previously found that the K141N mutation in heat shock protein B8(HSPB8) was responsible for Charcot-Marie-Tooth disease type 2L in a large Chinese family.The objective of the present study was to generate a transgenic mouse model bearing the K141N mutation in the human HSPB8 gene,and to determine whether this K141NHSPB8 transgenic mouse model would manifest the clinical phenotype of Charcot-Marie-Tooth disease type 2L,and consequently be suitable for use in studies of disease pathogenesis.Transgenic mice overexpressing K141NHSPB8 were generated using K141N mutant HSPB8 cDNA cloned into a pCAGGS plasmid driven by a human cytomegalovirus expression system.PCR and western blot analysis confirmed integration of the K141NHSPB8 gene and widespread expression in tissues of the transgenic mice.The K141NHSPB8 transgenic mice exhibited decreased muscle strength in the hind limbs and impaired motor coordination,but no obvious sensory disturbance at 6 months of age by behavioral assessment.Electrophysiological analysis showed that the compound motor action potential amplitude in the sciatic nerve was significantly decreased,but motor nerve conduction velocity remained normal at 6 months of age.Pathological analysis of the sciatic nerve showed reduced myelinated fiber density,notable axonal edema and vacuolar degeneration in K141NHSPB8 transgenic mice,suggesting axonal involvement in the peripheral nerve damage in these animals.These findings indicate that the K141NHSPB8 transgenic mouse successfully models Charcot-Marie-Tooth disease type 2L and can be used to study the pathogenesis of the disease. | Ruxu Zhang Fufeng Zhang Xiaobo Li Shunxiang Huang Xiaohong Zi Ting Liu Sanmei Liu Xuning Li Kun Xia Qian Pan Beisha Tang | 2014 | Neural Regeneration Research2014，9，4： | 1 |
| 18 | MicrowavetreatmentforenhancingtheliquidpermeabilityofChi-neseFir显示文摘 | HeSheng LinLanying FuFeng etal | 2014 | Bioresources2014，9，2： | 1 |
| 19 | Photosensitive Azopolymer Brushes via Atom Transfer Radical Polymerization for Protein Sensing显示文摘新奇感光性的 azopolymer 刷子经由表面被综合在 Au 上自我装配的开始的原子转移激进分子聚合使用开始者表面。偶氮苯衍生物的化学结构被 Fourier 变换证实红外线的光谱学(FTIR ) 和原子磁性的回声光谱学(NMR ) 。经由在不同时间的原子转移基聚合(ATRP ) 的 azopolymers 的表面形态学被原子力量显微镜学(AFM ) 调查。另外, azopolymer 的 photoisomerization 被紫外可见的光谱学测量(紫外力) 。结果显示如此的 azopolymers 能与紫外光由相片照耀高效地经历 trans-cis-trans photoisomerization。而且,这个 photoisomerization 性质能也导致牛的浆液白朊(BSA ) 的可逆吸附 azopolymer 刷子表面上的吸附。可逆过程的这吸附动力学能被表面电浆子测量在 situ 的回声(SPR ) 光谱学。它建议蛋白质生物晶片能被紫外照耀而非由与化学试剂被清洗安全地改革。 | Zhang, Zhihong Wang, Yaoli Yan, Fufeng Peng, Donglai Ma, Zhi | 2011 | Chinese Journal of Chemistry2011，29，1： | 1 |
| 20 | Isobaric vapor–liquid equilibrium for methanol<ce:hsp sp='0.25'/>+<ce:hsp sp='0.25'/>dimethyl carbonate<ce:hsp sp='0.25'/>+<ce:hsp sp='0.25'/>phosphoric-based ionic liquids显示文摘 | Fufeng Cai Xinying Wu Chang Chen Xiaochun Chen Charles Asumana Md Razibul Haque Guangren Yu | 2013 | Fluid Phase Equilibria2013，，： | 1 |
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