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| 1 | Recent advances of microneedles for biomedical applications: drug delivery and beyond显示文摘The microneedle(MN), a highly efficient and versatile device, has attracted extensive scientific and industrial interests in the past decades due to prominent properties including painless penetration, low cost, excellent therapeutic efficacy, and relative safety. The robust microneedle enabling transdermal delivery has a paramount potential to create advanced functional devices with superior nature for biomedical applications. In this review, a great effort has been made to summarize the advance of microneedles including their materials and latest fabrication method, such as three-dimensional printing(3DP). Importantly, a variety of representative biomedical applications of microneedles such as disease treatment, immunobiological administration, disease diagnosis and cosmetic field, are highlighted in detail. At last, conclusions and future perspectives for development of advanced microneedles in biomedical fields have been discussed systematically. Taken together, as an emerging tool, microneedles have showed profound promise for biomedical applications. | Jian Yang Xinli Liu Yunzhi Fu Yujun Song | 2019 | Acta Pharmaceutica Sinica B2019，9，3： | 21 |
| 2 | Cu_2ZnSnS_4 thin films prepared by sulfurization of ion beam sputtered precursor and their electrical and optical properties显示文摘Cu2ZnSnS4 (CZTS) thin films were successfully prepared by sulfurization of ion bean sputtered precursors on soda-lime glass substrate. The single phase of stannite-type structure CZTS films were obtained as revealed in EDS and XRD analysis when the ratios of the constituents of CZTS thin films are close to stoichiometric by optimizing the conditions of precursor preparation and sulfurization. A low sheet resistivity as about 0.156 Ω·cm and a high absorption coefficient as 1×104 cm-1 were achieved in this method by Hall effect measurements and UV-VIS spectrophotometer. The optical band-gap energy of the CZTS sample is about 1.51 eV, which is very close to the optimum value for a solar-cell absorber. | ZHANG Jun SHAO Lexi FU Yujun XIE Erqing | 2006 | Rare Metals2006，25，z1： | 11 |
| 3 | Deletion of SMARCA4 impairs alveolar epithelial type II cells proliferation and aggravates pulmonary fibrosis in mice显示文摘Alveolar epithelial cells(AECs)injury and failed reconstitution of the AECs barrier are both integral to alveolar flooding and subsequent pulmonary fibrosis(PF).Nevertheless,the exact mechanisms regulating the regeneration of AECs post-injury still remain unclear.SMARCA4 is a part of the large ATP-dependent chromatin remodelling complex SWI/SNF,which is essential for kidney and heart fibrosis.We investigates SMARCA4 function in lung fibrosis by establishing PF mice model with bleomycin firstly and found that the expression of SMARCA4 was mainly enhanced in alveolar type II(ATII)cells.Moreover,we established an alveolar epithelium-specific SMARCA4-deleted SP-C-rtTA/(tetO)7-Cre/SMARCA4f/f mice(SOSM4D/D)model,as well as a new SMARCA4-deleted alveolar type II(ATII)-like mle-12 cell line.We found that the bleomycin-induced PF was more aggressive in SOSM4D/D mice.Also,the proliferation of ATII cells was decreased with the loss of SMARCA4 in vivo and in vitro.In addition,we observed increased proliferation of ATII cells accompanied by abnormally high expression of SMARCA4 in human PF lung sections.These data uncovered the indispensable role of SMARCA4 in the proliferation of ATII cells,which might affect the progression of PF. | Danyi Peng Daozhu Si Rong Zhang Jiang Liu Hao Gou Yunqiu Xia Daiyin Tian Jihong Dai Ke Yang Enmei Liu Yujun Shi Q.Richard Lu Lin Zou Zhou Fu | 2017 | Genes & Diseases2017，4，4： | 3 |
| 4 | Effect of Monolithic LaB_6 on the Ablation Resistance of ZrC/SiC Coating Prepared by Supersonic Plasma Spraying for C/C Composites显示文摘Ablation resistance of monolithic LaB_6-doped ZrC coating for SiC-coated carbon/carbon composites by supersonic atmospheric plasma spray was investigated under an oxyacetylene torch with a heat flux of 4.18 MW/m^2. Result shows that ZrC coating with 10 vol.% LaB_6 has a good ablation resistance compared with pure ZrC, ZrC with 20 vol.% LaB_6 and SiC-doped ZrC coating. After ablation for 15 s, the weight is increased by 1.12 mg/s. The good ablation resistance is ascribed to the formation of a stabilized scale which consists of protective La_2Zr_2O_7-containing molten phase and ZrO_2 particles keeping the integrity of the coating. | Yujun Jia Hejun Li Lu Li Qiangang Fu Kezhi Li | 2016 | Journal of Materials Science & Technology2016，32，10： | 2 |
| 5 | Numerical Simulation of Microwaveassisted Depolymerization of Kraft Lignin显示文摘Kraft lignin has the potential to replace traditional fossil resources for the preparation of high-value chemicals because it is rich in aromatic rings and active functional groups.An effective method for the pyrolysis of kraft lignin into chemicals/fuels is microwave-assisted depolymerization.A simulation model is urgently needed to illustrate the coupling effect and mechanism of lignin conversion during the depolymerization process.In this study,COMSOL Multiphysics was used to simulate the microwave-assisted depolymerization process.The results showed that microwave power had a significant effect on the electric field and temperature distribution in the microwave cavity,while the reaction time had little effect on the electric field.The effect of the nitrogen flow rate on the electric field and temperature was negligible.The intensity of the electric field,heating rate of lignin,and final temperature of lignin depolymerization increased with increasing microwave power. | Zhenhao Ma Wenliang Wang Jiale Huang Yujun Ma Hui Miao Yishuai Fu Xiaoxiao Ren | 2021 | Paper And Biomaterials2021，6，4： | 2 |
| 6 | Influence of substrate temperature and nitrogen gas on zinc nitride thin films prepared by RF reactive sputtering显示文摘 | Zhang Jun Xie Erqing Fu Yujun | 2007 | Chinese J Semicond2007，28，8： | 1 |
| 7 | 显示文摘 | He Shuli He Kaiyuan Wang Z Cheng Lizhi and Fu Yujun | 1997 | Chin Phys Lett1997，14，6： | 1 |
| 8 | Facile synthesis of Co-SBA-16 mesoporous molecular sieves with EISA method and their applications for hydroxylation of benzene显示文摘 | Yongli Dong Xinlin Zhan Xiaoyu Niu Jing Li Fulong Yuan Yujun Zhu Honggang Fu | 2014 | Microporous and Mesoporous Materials2014，，： | 1 |
| 9 | Microstructure and mechanical property of directionally solidified NiAl–Cr(Mo)–(Hf, Dy) alloy at different withdrawal rates显示文摘 | Lei Wang Jun Shen Zhao Shang Jianfei Zhang Yujun Du Hengzhi Fu | 2014 | Materials Science & Engineering A2014，，： | 1 |
| 10 | Physical characteristic study of LiCoO2 prepared by molten salt synthesis method in 550 - 800C 显示文摘 | Juan Fu Ying Bai Caiyun Liu Hongjing Yu Yujun Mo | 2009 | Materials Chemistry and Physics2009，115，： | 1 |
| 11 | Investigations on the microstructure and room temperature fracture toughness of directionally solidified NiAl–Cr(Mo) eutectic alloy显示文摘 | Zhao Shang Jun Shen Lei Wang Yujun Du Yilong Xiong Hengzhi Fu | 2015 | Intermetallics2015，，： | 1 |
| 12 | Phase and Microstructure Selection During Directional Solidification of Peritectic Alloy Under Convection Condition显示文摘A phase and microstructure selection map used for peritectic alloy directionally solidified under convection condition was presented,which is based on the nucleation,constitutional undercooling criterion(NCU criterion),and the highest interface temperature criterion.This selection map shows the relationships between the phase/microstructure,the G/V ratio(G is the temperature gradient,V is the growth velocity),and the alloy composition under different convection intensities and nucleation undercoolings.Comparing with the results from directional solidification experiments of Sn–Cd peritectic alloys,this selection map was generally in agreement with the experimental results. | Lingshui Wang Jun Shen Yilong Xiong Yujun Du Hengzhi Fu | 2014 | Acta Metallurgica Sinica(English Letters)2014，27，4： | 1 |
| 13 | High-performance aqueous asymmetric supercapacitors based on the cathode of one-step electrodeposited cracked bark-shaped nickel manganese sulfides on activated carbon cloth显示文摘In this work,we report a high-performance self-standing supercapacitor electrode of mixed nickel manganese sulfides (NMSs)with a cracked-bark shape grown by one-step electrochemical deposition on activated carbon cloth (ACC).The electrode possesses outstanding electrochemical properties,including a high specific capacitance of up to 3142.8 F g^(-1)at 1.0 A g^(-1),the high-rate performance (~1206.8 F g^(-1)at 60.0 A g^(-1)),and cycle stability (~92.3%capacitance retention after 8000 cycles at8 A g^(-1)).An asymmetric supercapacitor assembled using NMSs on ACC as the cathode,activated carbon on carbon cloth as the anode and 1.0 mol L;KOH as the electrolyte delivers a high energy density of 111.2 W h kg^(-1)at 800.0 W kg^(-1)and the prominent cycling performance of~93.2%capacitance retention after 10000 cycles at 5 A g^(-1)with the Columbic efficiency of around 100%during these 10000 cycles.The high performance and facile preparation indicate that the NMSs on ACC hold a huge potential as the electrode for supercapacitors. | ADIL Emin XIE WenLu LONG Xiao WANG Xiao SONG XiaoQiang CHEN Yue FU YuJun LI JunShuai LI YaLi HE DeYan | 2022 | Science China(Technological Sciences)2022，65，2： | 1 |
| 14 | 消化道神经内分泌肿瘤临床病理特征及预后因素分析(英文)显示文摘Objective: The aim of the study was to analyze the clinicopathologic characteristics of gastroenteropancreatic neuroendocrine neoplasm(GEP-NEN) and to explore the prognostic factors for patients and differences of immunohistochemical markers between neuroendocrine tumor(NET) and neuroendocrine carcinoma(NEC). Methods: Retrospective reviews were conducted for the charts of 119 patients with GEP-NEN at the Affiliated Hospital of Qingdao University(China) from August 2003 to December 2013. Kaplan-Meier method was used to do the overall survivals analysis for the patients at different levels of predictive factors. Meanwhile, Cox proportional hazard model was used to select independent risk factors of survival. Analysis of variance was used to compare the expression of immunohistochemical markers among different pathological grades. Results: Among 119 patients, pancreas(45/119, 37.82%) and rectum(33/119, 27.73%) were mostly involved. The onset age of GEP-NEN in female group was younger than that of the male group. There were 13 deaths(10.92%) during 18.9(0.1–133.4) months follow-up period. Multivariate analysis indicated that neural invasion, gender and pathological grades of NET and NEC were independent risk factors. In neuroendocrine neoplasm(NEN), Syn expression in G2 was higher than G1 and G3, while Cg A showed no significant difference. All markers showed no significant differences between NET and NEC. Conclusion: GEP-NEN may occur at multiple sites of digestive system and lack specific clinical manifestations. Syn expression detected for the prognosis of G1, G2 and G3 tumors have clinical significance. Neural invasion, sex and pathological grades were independent prognostic factors for GEP-NEN patients. No significant difference was found in different pathological grades of NET and NEC. | Ping Yang Jie Liu Dongliang Lin Haiyang Fu Jing Chu Feng Li Guiyan Han Yujun Li Weiwei Fu | 2014 | The Chinese-German Journal of Clinical Oncology2014，13，12： | 1 |
| 15 | Facile synthesis of NiMn2S4 nanoflakes on nickel foam for high-performance aqueous asymmetric supercapacitors显示文摘Supercapacitors display promising electrochemical performance with high power density and excellent cycle stability.However,their low energy density limits their advancement in a broader range of applications.To enhance their energy density,we proposed self-assembled spinel NiMn2S4nanoflakes grown on nickel foam which we successfully prepared by a facile hydrothermal method.The NiMn2S4electrode delivers a high capacitance of 2096.7 F g^(-1)at 1.0 A g^(-1),with an exceptional rate capability(~720.6 F g^(-1)at a very high current density of 100 A g^(-1))and good cycle stability(~85.1%retention of the initial capacitance after 7000 cycles with the Coulombic efficiency around 100%).The as-fabricated asymmetric supercapacitors based on NiMn2S4nanoflakes//active carbon demonstrate an energy density of 73.6 W h kg^(-1)at 800.5 W kg^(-1)and adequate cycling performance of~84.6%capacitance retention at 15 A g^(-1)after 10000 cycles.The results reveal that the nanostructured NiMn2S4is an excellent electrode material for high-performance energy storage applications. | ADIL Emin LI YaLi GAO Zhe DONG YunXia LI DongHao CHEN YongChao FU YuJun HE DeYan LI JunShuai | 2024 | Science China(Technological Sciences)2024，67，2： | 0 |
| 16 | Determination of Double Beta Decay Half-Life of 136Xe with the PandaX-4T Natural Xenon Detector显示文摘Precise measurement of two-neutrino double beta decay(DBD)half-life is an important step for the searches of Majorana neutrinos with neutrinoless double beta decay.We report the measurement of DBD half-life of 136xe using the Pandax-4T dual-phase Time Projection Chamber(TPC)with 3.7-tonne natural xenon and the first 94.9-day physics data release. | Lin Si Zhaokan Cheng Abdusalam Abdukerim Zihao Bo Wei Chen Xun Chen Yunhua Chen Chen Cheng Yunshan Cheng Xiangyi Cui Yingjie Fan Deqing Fang Changbo Fu Mengting Fu Lisheng Geng Karl Giboni Linhui Gu Xuyuan Guo Ke Han Changda He Jinrong He Di Huang Yanlin Huang Zhou Huang Ruquan Hou Xiangdong Ji Yonglin Ju Chenxiang Li Jiafu Li Mingchuan Li Shu Li Shuaijie Li Qing Lin Jianglai Liu Xiaoying Lu Lingyin Luo Yunyang Luo Wenbo Ma Yugang Ma Yujun Mao Yue Meng Nasir Shaheed Xiaofeng Shang Xuyang Ning Ningchun Qi Zhicheng Qian Xiangxiang Ren Changsong Shang Guofang Shen Wenliang Sun Andi Tan Yi Tao Anqing Wang Meng Wang Qiuhong Wang Shaobo Wang Siguang Wang Wei Wang Xiuli Wang Zhou Wang Yuehuan Wei Mengmeng Wu Weihao Wu Jingkai Xia Mengjiao Xiao Xiang Xiao Pengwei Xie Binbin Yan Xiyu Yan Yong Yang Chunxu Yu Jumin Yuan Ying Yuan Zhe Yuan Dan Zhang Minzhen Zhang Peng Zhang Shibo Zhang Shu Zhang Tao Zhang Li Zhao Qibin Zheng Jifang Zhou Ning Zhou Xiaopeng Zhou Yong Zhou | 2023 | Research2023，，2： | 0 |
| 17 | Improved comprehensive performance of CsPbI_(2) Br perovskite solar cells by modifying the photoactive layers with carbon nanodots显示文摘Introducing additives into perovskite layers is an effective method to enhance the power conversion efficiency(PCE)and operation stability of perovskite solar cells(PSCs).Herein,we reported an addition of carbon nanodots(CNDs)into the CsPbI_(2) Br photoactive layer to boost performance of the related PSCs.It is found that the trap density can be notably suppressed,and the crystallinity can be enhanced after introducing CNDs with an optimal quantity.The PSC with 1.0 wt%addition of CNDs delivers a notable improved average PCE of 13.77%(the highest PCE:14.69%)from that of 12.14%for the control device without CND addition.Moreover,the CND-added CsPbI 2 Br PSCs exhibit superior stability,i.e.,~86% retention of the initial PCE after 160 h aging in air with the humidity of 20%-30%,to the control device. | Yanzhou Wang Caidong Xie Xincheng Yao Qiulu Chen Weining Liu Yujun Fu Qiming Liu Junshuai Li Yali Li Deyan He | 2022 | Journal of Materiomics2022，8，2： | 0 |
| 18 | Enhancement of photoelectric performance for CsPbI2Br solar cells by the synergistic effect of binary additives显示文摘CsPbI_(2)Br-based perovskite solar cells(PSCs)have attracted much attention because of their excellent phase stability and appropriate bandgap.However,numerous defects of undercoordinated ions or mobile species are the sites of carrier nonradiative recombination,causing a low power conversion efficiency(PCE).In this work,NaCl and nitrogen-doped graphene quantum dots(N-GQDs)as binary additives are introduced into perovskite precursor to obtain high-quality photoactive films.Chloride ion(Cl^(-))is incorporated into perovskite due to the same physical and chemical properties as bromine(Br^(-)),that align the energy level of CsPbI_(2)Br,decrease the energy barrier between perovskite and P3HT to promote carrier transport and extraction,hence result in the reduced energy loss.Meanwhile,because of its good conductivity,N-GQDs at grain boundaries can rapidly conduct photogenerated electrons to SnO_(2),suppressing carrier recombination at grain boundaries.Furthermore,the trap state density of the CsPbI_(2)Br film with binary additives is reduced,which could prolong the carrier lifetime,and improve surface morphology.As a result,a PCE of 15.37%for CsPbI_(2)Br PSCs with binary additives is obtained,which shows~22.76%relative increment compare with the pristine PSCs.Therefore,a simple and convenient optimization strategy of binary additives for PSCs is proposed in this work. | Qiulu Chen Like Lin Yanzhou Wang Zhe Gao Yujun Fu Qiming Liu Junshuai Li Deyan He | 2023 | Journal of Materiomics2023，9，1： | 0 |
| 19 | The innate interfacial elastic strain field of a transformable B2 precipitate embedded in an amorphous matrix显示文摘When a transformable B2 precipitate is embedded in an amorphous matrix,it is often experimentally observed that the crystalline-amorphous interface not only serves as an initiation site for the martensitic transformation due to local stress concentrations,but also as an inhibitor to stabilize the transformation,the latter being attributed to the“confinement effect”exerted by the amorphous matrix,according to the Eshelby solution.These two seemingly incongruous factors are examined in this study using molecular dynamics simulations from an atomic interaction perspective.An innate strain gradient in the vicinity of the crystalline-amorphous interface is identified.The actual interface,the compressive/dilatative transition,and the interfacial maximum strain are investigated to differentiate from the conventional“interface”located within a distance of a few nanometers.Our innate interfacial elastic strain field model is applicable for the design of materials with a higher degree of martensitic transformation and controllable stress concentration,even in cryogenic environments. | Xiaoling Fu Yujun Lin Mixun Zhu Kai Wang Jiaqing Wu Xing Tong Wenli Song Ming Jen Tan Yuanzheng Yang Jun Shen Gang Wang Chan Hung Shek Robert O.Ritchie | 2023 | npj Computational Materials2023，，1： | 0 |
| 20 | Present Situation and Problems of Application of New Media in Rural E-commerce : A Case Study of Anhui Province显示文摘The application of new media technology in rural areas of China provides more convenient conditions for agricultural products publicity,transaction information dissemination and user feedback.In particular,e-commerce platform based on Internet technology provides more convenient sales channels for characteristic agricultural products.Through the research on the application of new media technology in rural areas of Anhui Province,this paper explores the actual effect of new media technology on the development of rural e-commerce.The questionnaire survey is used to understand the development status of new media in rural areas of China.They are:the development of'Internet government affairs'has begun to take shape;the official account of WeChat has shortened the time and space between the production and consumption of agricultural products.Live interaction gives full play to the powerful role of fan economy;digital media has not been widely used.Through the form of on-the-spot visits,this paper expounds the application effect of new media in the agricultural field of Anhui Province from three perspectives of the government,agricultural enterprises and farmers.It analyzes the problems existing in the application of new media in rural e-commerce in Anhui Province.They are:the new media market is still full of problems;The infrastructure construction of rural e-commerce is relatively poor;Farmers lack the guidance of professional talents;farmers' acceptance and learning ability is poor.The paper puts forward suggestions for the development status and problems of new media in rural areas of Anhui Province.They are:the provincial government should continue to promote the new media market order;all e-commerce enterprises should actively undertake social responsibility;rural e-commerce entrepreneurs should actively promote professional operation;farmers should actively change their views on new media. | Shuhua CAO Yujun HU Peijun FU | 2021 | Asian Agricultural Research2021，13，10： | 0 |
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