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| 1 | A novel therapeutic approach to 6-OHDA-induced Parkinson's disease in rats via supplementation of PTD-conjugated tyrosine hydroxylase显示文摘 | Wu SP Fu AL Wang YX Yu LP Jia PY Li Q Jin GZ Sun MJ | 2006 | 中国生物学文摘2006，20，10： | 9 |
| 2 | Antisense inhibition of acetylcholinesterase gene expression for treating cognition deficit in Alzheimer's disease model mice显示文摘 | Fu AL Zhang XM Sun MJ | 2006 | 中国生物学文摘2006，20，10： | 2 |
| 3 | Immunogenicity and safety of NVSI-06-07 as a heterologous booster after priming with BBIBP-CorV:a phase 2 trial显示文摘The increased coronavirus disease 2019(COVID-19)breakthrough cases pose the need of booster vaccination.We conducted a randomised,double-blinded,controlled,phase 2 trial to assess the immunogenicity and safety of the heterologous prime-boost vaccination with an inactivated COVID-19 vaccine(BBIBP-CorV)followed by a recombinant protein-based vaccine(NVSI-06-07),using homologous boost with BBIBP-CorV as control.Three groups of healthy adults(600 individuals per group)who had completed two-dose BBIBP-CorV vaccinations 1–3 months,4–6 months and≥6 months earlier,respectively,were randomly assigned in a 1:1 ratio to receive either NVSI-06-07 or BBIBP-CorV boost.Immunogenicity assays showed that in NVSI-06-07 groups,neutralizing antibody geometric mean titers(GMTs)against the prototype SARS-CoV-2 increased by 21.01–63.85 folds on day 28 after vaccination,whereas only 4.20–16.78 folds of increases were observed in control groups.For Omicron variant,the neutralizing antibody GMT elicited by homologous boost was 37.91 on day 14,however,a significantly higher neutralizing GMT of 292.53 was induced by heterologous booster.Similar results were obtained for other SARS-CoV-2 variants of concerns(VOCs),including Alpha,Beta and Delta.Both heterologous and homologous boosters have a good safety profile.Local and systemic adverse reactions were absent,mild or moderate in most participants,and the overall safety was quite similar between two booster schemes.Our findings indicated that NVSI-06-07 is safe and immunogenic as a heterologous booster in BBIBP-CorV recipients and was immunogenically superior to the homologous booster against not only SARS-CoV-2 prototype strain but also VOCs,including Omicron. | Nawal Al Kaabi Yun Kai Yang Jing Zhang Ke Xu Yu Liang Yun Kang Ji Guo Su Tian Yang Salah Hussein Mohamed Saif ElDein Shuai Shao Sen Sen Yang Wenwen Lei Xue Jun Gao Zhiwei Jiang Hui Wang Meng Li Hanadi Mekki Mekki Walid Zaher Sally Mahmoud Xue Zhang Chang Qu Dan Ying Liu Jing Zhang Mengjie Yang Islam Eltantawy Peng Xiao Zhao Nian Wang Jin Liang Yin Xiao Yan Mao Jin Zhang Ning Liu Fu Jie Shen Liang Qu Yun Tao Zhang Xiao Ming Yang Guizhen Wu Qi Ming Li | 2022 | Signal Transduction and Targeted Therapy2022，7，7： | 2 |
| 4 | MicroRNA let-7 regulates 3T3-L1 adipogenesis显示文摘 | Sun T Fu M Bookout AL | 2009 | M ol Endocrinol2009，23，6： | 1 |
| 5 | MicroRNA let-7 regulates 3T3-L1 adipogenesis 显示文摘 | Sun T Fu M Bookout AL | 2009 | Molecular Endocrinology2009，23，6： | 1 |
| 6 | Alternative therapy of Alzheimer's disease via supplementation with choline acetyltransferase显示文摘 | Fu AL Li Q Dong ZH | 2004 | Neurosci Lett2004，368，： | 1 |
| 7 | Regulation of inflammation by the NF- g B pathway in ovarian cancer stem cells显示文摘 | Leizer AL Alvero AB Fu HH et at | 2011 | American journal of reproductive immunolagy2011，65，4： | 1 |
| 8 | is correlated with clinical progression and unfavorable prognosis in pancreatic cancer显示文摘 | Pang EJ Yang R Fu XB et aL Overexpression of long non -coding RNA MALATl | 2015 | Tumour Bioi2015，36，4： | 1 |
| 9 | Value of ultra-guided biopsy for diagnosing diffuse breast lesions显示文摘 | Liu AL Liu RH Fu JF | 2001 | Chinese J Ultrasound Med(Chinese)2001，17，： | 1 |
| 10 | High -level expression of a sika deer (Cervus nippon) Cu/Zn superoxide dismutase in Pichia pastoris and its characterization 显示文摘 | Li RK Fu CL Ghen P et aL | 2013 | Environ Toxicol Pharmacol2013，35，2： | 1 |
| 11 | Molecular epidemiological analy-sis of Japanese encephalitis virus in China显示文摘 | WANG H Y TOMOHIKO FU S He t al | 2007 | J Gen Virol2007，8，： | 1 |
| 12 | Orally fast disintegrating tablets: develop- ments, technologies, taste - masking and clinical studies显示文摘 | Fu YR Yang SC Jeong SH el al | 2004 | Crit Rev Ther Drug Carrier Syst2004，21，6： | 1 |
| 13 | Surgical pathologic variables predictive of local recurrent in squamous cell carcinoma of the vulva显示文摘 | Fu YS Montz FJ at al | 1990 | Gynecol Oncol1990，38，3： | 1 |
| 14 | Oleoylethanolamide stimulates lipolysis by activating the nuclear receptor peroxisome proliferator-activated receptor a(PPAR-α) 显示文摘 | Guzman M Lo Verme J Fu J ct al | 2004 | J Biol Chem2004，279，27： | 1 |
| 15 | Extraction of Th( W ) from Aqueous Solution by Room-Temperature Ionic Liquids andCoupled with Supercritical Carbon Dioxide Stripping显示文摘 | Fu J Chen Q D Sun T X ei al | 2013 | Sep Purif Technol2013，119，： | 1 |
| 16 | Study on injectable and degradablecement of calcium sulphate and calcium phosphate for bone repair显示文摘 | Hu G Xiao L Fu H ef al | 2010 | J Mater Sci Mater Med2010，21，2： | 1 |
| 17 | Corrosion Science显示文摘 | Fu Q G Li H J Wang Y J C al | 2009 | 51: 24502009，51，： | 1 |
| 18 | MicroRNA let-7 regulates 3T3- LI adipogenesis显示文摘 | Sun T Fu M Bookout AL | 2009 | Mol Endocrinol2009，23，6： | 1 |
| 19 | Effect of norcantharidin on proliferation and invasion of human gallbladder carcinoma GBC-SD cell显示文摘 | Fan YZ Fu JY Zhao ZM el al | 2005 | World J Gastroentero2005，11，16： | 1 |
| 20 | In situ formation of TiC composite u-sing selective laser melting 显示文摘 | 1X1 I: FU H H J Y el al | 2000 | MaU''iials Research Bulletin2000，35，15： | 1 |
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