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| 1 | Device-associated infection rates, mortality, length of stay and bacterial resistance in intensive care units in Ecuador: International Nosocomial Infection Control Consortium's findings显示文摘AIM To report the results of the International Nosocomial Infection Control Consortium(INICC) study conducted in Quito, Ecuador.METHODS A device-associated healthcare-acquired infection(DAHAI) prospective surveillance study conducted from October 2013 to January 2015 in 2 adult intensive care units(ICUs) from 2 hospitals using the United States Centers for Disease Control/National Healthcare Safety Network(CDC/NHSN) definitions and INICC methods. RESULTS We followed 776 ICU patients for 4818 bed-days. The central line-associated bloodstream infection(CLABSI) rate was 6.5 per 1000 central line(CL)-days, the ventilator-associated pneumonia(VAP) rate was 44.3 per 1000 mechanical ventilator(MV)-days, and the catheterassociated urinary tract infection(CAUTI) rate was 5.7 per 1000 urinary catheter(UC)-days. CLABSI and CAUTI rates in our ICUs were similar to INICC rates [4.9(CLABSI) and 5.3(CAUTI)] and higher than NHSN rates [0.8(CLABSI) and 1.3(CAUTI)]- although device use ratios for CL and UC were higher than INICC and CDC/NSHN's ratios. By contrast, despite the VAP rate was higher than INICC(16.5) and NHSN's rates(1.1), MV DUR was lower in our ICUs. Resistance of A. baumannii to imipenem and meropenem was 75.0%, and of Pseudomonas aeruginosa to ciprofloxacin and piperacillin-tazobactam was higher than 72.7%, all them higher than CDC/NHSN rates. Excess length of stay was 7.4 d for patients with CLABSI, 4.8 for patients with VAP and 9.2 for patients CAUTI. Excess crude mortality in ICUs was 30.9% for CLABSI, 14.5% for VAP and 17.6% for CAUTI. CONCLUSION DA-HAI rates in our ICUs from Ecuador are higher than United States CDC/NSHN rates and similar to INICC international rates. | Estuardo Salgado Yepez Maria M Bovera Victor D Rosenthal Hugo A González Flores Leonardo Pazmino Francisco Valencia Nelly Alquinga Vanessa Ramirez Edgar Jara Miguel Lascano Veronica Delgado Cristian Cevallos Gasdali Santacruz Cristian Pelaéz Celso Zaruma Diego Barahona Pinto | 2017 | World Journal of Biological Chemistry2017，8，1： | 23 |
| 2 | Global Wheat Head Detection 2021:An Improved Dataset for Benchmarking Wheat Head Detection Methods显示文摘The Global Wheat Head Detection(GWHD)dataset was created in 2020 and has assembled 193,634 labelled wheat heads from 4700 RGB images acquired from various acquisition platforms and 7 countries/institutions.With an associated competition hosted in Kaggle,GWHD_2020 has successfully attracted attention from both the computer vision and agricultural science communities.From this first experience,a few avenues for improvements have been identified regarding data size,head diversity,and label reliability.To address these issues,the 2020 dataset has been reexamined,relabeled,and complemented by adding 1722 images from 5 additional countries,allowing for 81,553 additional wheat heads.We now release in 2021 a new version of the Global Wheat Head Detection dataset,which is bigger,more diverse,and less noisy than the GWHD_2020 version. | Etienne David Mario Serouart Daniel Smith Simon Madec Kaaviya Velumani Shouyang Liu Xu Wang Francisco Pinto Shahameh Shafiee Izzat SATahir Hisashi Tsujimoto Shuhei Nasuda Bangyou Zheng Norbert Kirchgessner Helge Aasen Andreas Hund Pouria Sadhegi-Tehran Koichi Nagasawa Goro Ishikawa Sébastien Dandrifosse Alexis Carlier Benjamin Dumont Benoit Mercatoris Byron Evers Ken Kuroki Haozhou Wang Masanori Ishii Minhajul ABadhon Curtis Pozniak David Shaner LeBauer Morten Lillemo Jesse Poland Scott Chapman Benoit de Solan Frédéric Baret Ian Stavness Wei Guo | 2021 | Plant Phenomics2021，3，1： | 2 |
| 3 | Volume visaalization and exploration through flexible transfer function design显示文摘 | Francisco de M Pinto Carla M D S Freitas | 2008 | Computers & Graphics2008，，32： | 1 |
| 4 | Isolation, identification, and activity in vitro of killer yeasts against Colletotrichum gloeosporioides isolated from tropical fruits显示文摘 | Jaqueline Rabelo de Lima Luciana Rocha Barros Gon?alves Luciana Rocha Brand?o Carlos Augusto Rosa Francisco Marto Pinto Viana | 2013 | J Basic Microbiol2013，，7： | 1 |
| 5 | Elderly patients on chronic hemodialysis: Effect of the secondary hyperparathyroidism on the hemoglobin level显示文摘 | Pedro L. Neves Julio Trivi?o Francisco Casaubon Paulo Rom?o Patricia Mendes Isilda Bexiga Isabel Pinto Viriato Santos Idalécio Bernardo | 2002 | International Urology and Nephrology2002，，1： | 1 |
| 6 | Detection of Lymphatic Micrometastases in Patients With Stages I and II Colorectal Cancer: Impact on Five-Year Survival显示文摘 | Udo Kronberg Francisco López-Kostner Gonzalo Soto Alvaro Zú?iga A. Ignacio Wistuba Vanessa Miranda Eliana Pinto Paola Viviani Guillermo Marshall | 2004 | Diseases of the Colon & Rectum2004，，7： | 1 |
| 7 | Pro-atherosclerotic markers and cardiovascular risk factors one year after liver transplantation显示文摘AIM:To investigate pro-atherosclerotic markers(endothelial dysfunction and inflammation)in patients one year after liver transplantation.METHODS:Forty-four consecutive liver transplant(LT)outpatients who were admitted between August2009 and July 2010,were followed-up by for 1 year,exhibited no evidences of infection or rejection,all of them underwent tacrolimus-based immunosuppressive regimens were consecutively enrolled.Inflammatory cytokines(TNFα,IFNγ,IL-8,and IL-10),endothelial biomarkers(sVCAM-1,sICAM-1,MPO,adiponectin,PAI-1,SAP,SAA,E-selectin,and MMP-9),high sensitive C-reactive protein,and Framingham risk score(FRS)were assessed.The anthropometric data,aminotransferases,metabolic syndrome features,glucose and lipid profiles,and insulin resistance data were also collected.The LT recipients were compared to 22 biopsy-proven non-alcoholic steatohepatitis(NASH)patients and 20healthy controls(non-obese,non-diabetics,and nondyslipidemic).RESULTS:The LT recipients had significantly younger ages and lower body mass indices,aminotransferases,fasting glucose and insulin levels,glucose homeostasis model and metabolic syndrome features than the NASH patients.Classic cardiovascular risk markers,such as Hs-CRP and FRS[2.0(1.0-8.75)],were lower in the LT patients compared to those observed in the NASH patients(P=0.009).In contrast,the LT recipients and NASH patients had similar inflammatory and endothelial serum markers compared to the controls(pg/mL):lower IL-10 levels(32.3 and 32.3 vs 62.5,respectively,P=0.019)and higher IFNγ(626.1 and 411.9 vs 67.9,respectively,P<0.001),E-selectin(48.5 and 90.03vs 35.7,respectively,P<0.001),sVCAM-1(1820.6and 1692.4 vs 1167.2,respectively,P<0.001),and sICAM-1(230.3 and 259.7 vs 152.9,respectively,P=0.015)levels.CONCLUSION:Non-obese LT recipients have similar pro-atherosclerotic serum profiles after a short 1-year follow-up period compared to NASH patients,suggesting a high risk of atherosclerosis in this population. | Mario Reis Alvares-da-Silva Claudia Pinto Marques Souza de Oliveira José Tadeu Stefano Hermes V Barbeiro Denise Barbeiro Francisco G Soriano Alberto Queiroz Farias Flair José Carrilho Luiz Augusto Carneiro D’Albuquerque | 2014 | World Journal of Gastroenterology2014，20，26： | 1 |
| 8 | Production of Aflatoxins from Aspergillus flavus in Liquid Medium显示文摘 | Maria Edite Bezerra da Rocha Francisco das Chagas Oliveira Freire Icaro Gusmao Pinto Vieira Jose Mariados Santos Filho Fabio Erlan Feitosa Maia Maria Izabel Florindo Guedes Davide Rondina | 2013 | Journal of Life Sciences2013，7，4： | 1 |
| 9 | Detection of Lymphatic Micrometastases in Patients With Stages I and II Colorectal Cancer: Impact on Five-Year Survival显示文摘 | Udo Kronberg M.D. Francisco López-Kostner M.D. Gonzalo Soto M.D. Alvaro Zú?iga A. M.D. Ignacio Wistuba M.D. Vanessa Miranda R.N. Eliana Pinto R.N. Paola Viviani M.S. (Statistics) Guillermo Marshall M.S. (Statistics) | 2004 | Diseases of the Colon & Rectum2004，，7： | 1 |
| 10 | Frey syndrome prevalence after partial parotidectomy 显示文摘 | Regiane Cristina Santos Jose Francisco de Salles Chagas Thiago Freire Pinto Bezerra | 2006 | Rev Bras Otorrinolaringol2006，72，1： | 1 |
| 11 | Analysis of the coffee harves- ting process using an electromagnetic shaker显示文摘 | Fabio Lucio Santos Daniel Marcal de Queiroz Francisco de Assis de Carvalho Pinto | 2010 | Acta Scien- tiarum Agronomy2010，32，3： | 1 |
| 12 | Infraareolar access for thoracoscopic sympathectomy to treat primary hyperhidrosis显示文摘 | S?nia Oliveira Lima Yasmin Gama Abuawad Paulo Sérgio Faro Santos Aloisio Ferreira Pinto Neto Vanessa Rocha Santana Francisco Prado Reis | 2013 | Surgery Today2013，，2： | 1 |
| 13 | The practice of coastal zone management in Portugal显示文摘 | Francisco Taveira Pinto | 2004 | Journal of Coastal Conservation2004，10，12： | 1 |
| 14 | Turbo-taxonomy to assemble a megadiverse lichen genus:seventy new species of Cora(Basidiomycota:Agaricales:Hygrophoraceae),honouring David Leslie Hawksworth’s seventieth birthday显示文摘Following a large-scale phylogenetic study of the lichenized genus Cora(Basidiomycota:Agaricales:Hygrophoraceae),we formally describe 70 new species,honouring the seventieth birthday of David Leslie Hawksworth,one of the preeminent figures in mycology and lichenology in the past 50 years.Based on an updated phylogeny using the ITS fungal barcoding locus,we now recognize 189 taxa in a genus that until recently was considered to represent a single species;including this contribution,92 of these are formally recognized,including five taxa based on historical names or collections that have not been sequenced.Species of Cora can be recognized by a combination of morphological(size,colour,lobe configuration,surface hairs,hymenophore size and shape),anatomical(thallus thickness,cortex structure,photobiont type,hyphal papillae),and ecogeographical features(substrate,habitat,distribution),and a keytable allowing the identification of all accepted taxa is provided.The new species are:Cora accipiter Moncada,Madrin˜a´n&Lücking spec.nov.,C.applanata Moncada,Soto-Medina&Lücking spec.nov.,C.arachnodavidea Moncada,Dal Forno&Lücking spec.nov.,C.arborescens Dal Forno,Chaves&Lücking spec.nov.,C.arcabucana Moncada,C.Rodrı´guez&Lücking spec.nov.,C.aturucoa Lücking,Moncada&C.Vargas spec.nov.,C.auriculeslia Moncada,Ya´nez-Ayabaca&Lücking spec.nov.,C.barbifera Moncada,Patin˜o&Lücking spec.nov.,C.boleslia Lücking,E.Morales&Dal Forno spec.nov.,C.caliginosa Holgado,Rivas Plata&Perlmutter spec.nov.,C.campestris Dal Forno,Eliasaro&Spielmann spec.nov.,C.canari Nugra,Dal Forno&Lücking spec.nov.,C.caraana Lücking,Martins&Lucheta spec.nov.,C.casasolana Moncada,R.-E.Pe´rez&Lücking spec.nov.,C.caucensis Moncada,M.Gut.&Lücking spec.nov.,C.celestinoa Moncada,CabreraAmaya&Lücking spec.nov.,C.comaltepeca Moncada,R.-E.Pe´rez&Herrera-Camp.spec.nov.,C.corani Lücking,E.Morales&Dal Forno spec.nov.,C.corelleslia Moncada,A.Sua´rez-Corredor&Lücking spec.nov.,C.crispoleslia Moncada,J.Molina&Lücking spec.nov.,C.cuzcoensis Holgado,Rivas Plata&Perlmutter spec.nov.,C.dalehana Moncada,Madrin˜a´n&Lücking spec.nov.,C.davibogotana Lücking,Moncada&Coca spec.nov.,C.davicrinita Moncada,Madrin˜a´n&Lücking spec.nov.,C.davidia Moncada,L.Vargas&Lücking spec.nov.,C.dewisanti Moncada,A.Sua´rez-Corredor&Lücking spec.nov.,C.dulcis Moncada,R.-E.Pe´rez&Lücking spec.nov.,C.elephas Lücking,Moncada&L.Vargas spec.nov.,C.fuscodavidiana Lücking,Moncada&L.Vargas spec.nov.,C.garagoa Simijaca,Moncada&Lücking spec.nov.,C.gigantea Lücking,Moncada&Coca spec.nov.,C.gomeziana Dal Forno,Chaves&Lücking spec.nov.,C.guajalitensis Lücking,Robayo&Dal Forno spec.nov.,C.hafecesweorthensis Moncada,Lücking&R.Pela´ez spec.nov.,C.haledana Dal Forno,Chaves&Lücking spec.nov.,C.hawksworthiana Dal Forno,P.Nelson&Lücking spec.nov.,C.hochesuordensis Lücking,E.Morales&Dal Forno spec.nov.,C.hymenocarpa Lücking,Chaves&Lawrey spec.nov.,C.imi Lücking,Chaves&Lawrey spec.nov.,C.itabaiana Dal Forno,Aptroot&M.Ca´ceres spec.nov.,C.leslactuca nov.,C.maxima Wilk,Dal Forno&Lücking spec.nov.,C.minutula Lücking,Moncada&Ya´nez-Ayabaca spec.nov.,C.palaeotropica Weerakoon,Aptroot&Lücking spec.nov.,C.palustris Dal Forno,Chaves&Lücking spec.nov.,C.parabovei Dal Forno,Kukwa&Lücking spec.nov.,C.paraciferrii Lücking,Moncada&J.E.Hern.spec.nov.,C.paraminor Dal Forno,Chaves&Lücking spec.nov.,C.pastorum Moncada,Patin˜o&Lücking spec.nov.,C.pichinchensis Paredes,Jonitz&Dal Forno spec.nov.,C.pikynasa J.-M.Torres,Moncada&Lücking spec.nov.,C.pseudobovei Wilk,Dal Forno&Lücking spec.nov.,C.pseudocorani Lücking,E.Morales&Dal Forno spec.nov.,C.putumayensis L.J.Arias,Moncada&Lücking spec.nov.,C.quillacinga Moncada,F.Ortega&Lücking spec.nov.,C.rothesiorum Moncada,Madrin˜a´n&Lücking spec.nov.,C.rubrosanguinea Nugra,Moncada&Lücking spec.nov.,C.santacruzensis Dal Forno,Bungartz&Ya´nezAyabaca,spec.nov.,C.schizophylloides Moncada,C.Rodrı´guez&Lücking spec.nov.,C.smaragdina Lücking,Rivas Plata&Chaves spec.nov.,C.soredavidia Dal Forno,Marcelli&Lücking spec.nov.,C.subdavicrinita Moncada,J.Molina&Lücking spec.nov.,C.suturifera Nugra,Besal&Lücking spec.nov.,C.terrestris Dal Forno,Chaves&Lücking spec.nov.,C.terricoleslia Wilk,Dal Forno&Lücking spec.nov.,C.udebeceana Moncada,R.Pela´ez&Lücking,Moncada&R.Pela´ez spec.Lücking spec.nov.,C.urceolata Moncada,Coca&Lücking spec.nov.,C.verjonensis Lücking,Moncada&Dal Forno spec.nov.,C.viliewoa Lücking,Chaves&Soto-Medina spec.nov.,and C.yukiboa Mercado-Dı´az,Moncada&Lücking spec.nov.Furthermore,the taxonomic status of the recently described or recognized species C.arachnoidea,C.aspera,C.ciferrii,and C.reticulifera,is revised. | Robert Lücking Manuela Dal Forno Bibiana Moncada Luis Fernando Coca Leidy Yasmín Vargas-Mendoza André Aptroot Laura Juliana Arias Betty Besal Frank Bungartz Diego Mauricio Cabrera-Amaya Marcela E.S.Cáceres José Luis Chaves Sionara Eliasaro Martha Cecilia Gutiérrez Jesús E.Hernández Marin María de los Ángeles Herrera-Campos María E.Holgado-Rojas Harald Jonitz Martin Kukwa Fabiane Lucheta Santiago Madriñán Marcelo Pinto Marcelli Suzana Maria de Azevedo Martins Joel A.Mercado-Díaz Jorge Alberto Molina Eduardo A.Morales Peter R.Nelson Freddy Nugra Francisco Ortega Telma Paredes Ayda Lucía Patiño Rouchi Nadine Peláez-Pulido Rosa Emilia Pérez Pérez Gary B.Perlmutter Eimy Rivas-Plata Javier Robayo Camilo Rodríguez Diego Fernando Simijaca Edier Soto-Medina Adriano Afonso Spielmann Alejandra Suárez-Corredor Jean-Marc Torres Carlos Alberto Vargas Alba Yánez-Ayabaca Gothamie Weerakoon Karina Wilk Marcela Celis Pacheco Mauricio Diazgranados Grischa Brokamp Thomas Borsch Patrick M.Gillevet Masoumeh Sikaroodi James D.Lawrey | 2017 | Fungal Diversity2017，，3： | 0 |
| 15 | Spectral reflectance indices as proxies for yield potential and heat stress tolerance in spring wheat: heritability estimates and marker-trait associations显示文摘The application of spectral reflectance indices(SRIs) as proxies to screen for yield potential(YP) and heat stress(HS) is emerging in crop breeding programs.Thus, a comparison of SRIs and their associations with grain yield(GY) under YP and HS conditions is important.In this study, we assessed the usefulness of 27 SRIs for indirect selection for agronomic traits by evaluating an elite spring wheat association mapping initiative(WAMI) population comprising 287 elite lines under YP and HS conditions.Genetic and phenotypic analysis identified 11 and 9 SRIs in different developmental stages as efficient indirect selection indices for yield in YP and HS conditions,respectively.We identified enhanced vegetation index(EVI) as the common SRI associated with GY under YP at booting, heading and late heading stages, whereas photochemical reflectance index(PRI) and normalized difference vegetation index(NDVI) were the common SRIs under booting and heading stages in HS.Genomewide association study(GWAS) using 18704 single nucleotide polymorphisms(SNPs) from Illumina i Select90 K identified 280 and 43 marker-trait associations for efficient SRIs at different developmental stages under YP and HS, respectively.Common genomic regions for multiple SRIs were identified in 14 regions in 9 chromosomes: 1 B(60–62 cM), 3 A(15, 85–90, 101–105 cM), 3 B(132–134 cM), 4 A(47–51 cM), 4 B(71–75 cM), 5 A(43–49, 56–60, 89–93 cM), 5 B(124–125 cM),6 A(80–85 cM), and 6 B(57–59, 71 cM).Among them,SNPs in chromosome 5 A(89–93 cM) and 6 A(80–85 cM)were co-located for yield and yield related traits.Overall,this study highlights the utility of SRIs as proxies for GY under YP and HS.High heritability estimates and identification of marker-trait associations indicate that SRIs are useful tools for understanding the genetic basis of agronomic and physiological traits. | Caiyun LIU Francisco PINTO CMariano COSSANI Sivakumar SUKUMARAN Matthew PREYNOLDS | 2019 | Frontiers of Agricultural Science and Engineering2019，6，3： | 0 |
| 16 | Advances in cellular technology in the hematology field: What have we learned so far?显示文摘Despite the advances in the hematology field, blood transfusion-related iatrogenesis is still a major issue to be considered during such procedures due to blood antigenic incompatibility. This places pluripotent stem cells as a possible ally in the production of more suitable blood products. The present review article aims to provide a comprehensive summary of the state-of-theart concerning the differentiation of both embryonic stem cells and induced pluripotent stem cells to hematopoietic cell lines. Here, we review the most recently published protocols to achieve the production of blood cells for future application in hemotherapy, cancer therapy and basic research. | Gustavo Torres de Souza Claudineia Pereira Maranduba Camila Maurmann de Souza Danielle Luciana Aurora Soares do Amaral Francisco Carlos da Guia Rafaella de Souza Salomao Zanette Joao Vitor Paes Rettore Natana Chaves Rabelo Lucas Mendes Nascimento Icaro Franca Navarro Pinto Julia Boechat Farani Abrahao Elias Hallack Neto Fernando de Sa Silva Carlos Magno da Costa Maranduba Angelo Atalla | 2015 | World Journal of Stem Cells2015，7，1： | 0 |
| 17 | Experimental study on the wear evolution of different PVD coated tools under milling operations of LDX2101 duplex stainless steel显示文摘Duplex stainless steels are being used on applications that require,especially,high corrosion resistance and overall good mechanical properties,such as the naval and oil-gas exploration industry.The components employed in these industries are usually obtained by machining,however,these alloys have low machinability when compared to conventional stainless steels.In this work,a study of the wear developed when milling duplex stainless-steel,LDX 2101,is going to be presented and evaluated,employing four types of milling tools with different geometries and coatings,while studying the influence of feed rate and cutting length in the wear of these tools.Tools used have been provided with two and four flutes,as well as three different coatings,namely:TiAlN,TiAlSiN and AlCrN.The cutting behavior of these tools was analyzed;data relative to the cutting forces developed during the process were obtained;and roughness measurements of the machined surfaces were executed.The tools were then submitted to scanning electron microscope(SEM)analysis,enabling the identification of the wear mechanisms that tools were subjected to when machining this material,furthermore,the early stages of these mechanisms were also identified.All this work was done with the goal of relating the machining parameters and cutting force values obtained,identifying,and discussing the wear patterns that were observed in the coating and tools after the milling tests,providing further information on the machining of these alloys. | Vitor F.C.Sousa Francisco J.G.Silva Ricardo Alexandre Jose S.Fecheira Gustavo Pinto Andresa Baptista | 2023 | Advances in Manufacturing2023，11，1： | 0 |
| 18 | 冠向复位瓣结合带蒂上皮下结缔组织移植重建牙龈乳头:2例病例报告显示文摘本病例报告介绍了如何采用冠向复位结合带蒂上皮下结缔组织术重建牙龈乳头。该技术成功应用于以下两种特定情况:重建右上侧切牙与尖牙之间缺失的牙间乳头.覆盖这两牙之间的两个MillerIV度牙龈退缩(病例1):重建左上中切牙与侧切牙之间缺失的牙间乳头并改善其美学效果(病例2)。病例1有新的临床附着获得,尖牙暴露的根面完全覆盖.牙龈乳头高度得到了提升。病例2中。牙间乳头有相似的改善.黑三角显著减小。上皮下带蒂结缔组织瓣转移联合冠向复位瓣术可以获得较满意的美学效果.无论手术位点是否伴有龈退缩.这种方法都可以考虑用于修复龈乳头,但还需要进一步研究。 | Rodrigo Carlos Nahas De Castro Pinto Bella Luna Colombini Sergio Kiyoshi Lshikiriama Leandro Chambrone Francisco EmilioPustiglioni Giuseppe Alexandre Romito 王宪娥(译) 徐莉(审) | 2011 | 中国口腔医学继续教育杂志2011，14，4： | 0 |
| 19 | Areas with evidence of equity and their progress on mortality from tuberculosis in an endemic municipality of southeast Brazil显示文摘Background:In Brazil,people still fall ill and die from tuberculosis(TB),and this can be explained by the significant impasse in the equity of distribution of therapeutic resources to the population as a whole.The aim was to identify geographical areas which have shown progress in terms of equity(of income,schooling and urban occupancy)and test its effect on mortality from TB in a municipality of southeast Brazil.Methods:It is an ecological study considering TB as the basic cause for deaths registered between 2006 and 2013 on the Mortality Information System and other variables obtained through the Demographic Census of the Brazilian Institute of Geography and Statistics(2010).The geographical area for analysis comprised the areas of coverage of the health services.Social indicators have been constructed through the Principal Component Analysis(PCA).The cases were geocoded and the annual mortality rate from TB was calculated with smoothing using the local empirical Bayesian method.Multiple linear regression was then performed.There was confirmation of the existence of spatial dependence of residue through the application of the Global Moran I test,and application of the Models with Global Spatial Effects,to identify the best standard of spatial regression.Results:The mortality rates ranged from 0.00 to 2.8 deaths per 100,000 people,per year.In the PCA,three indicators were constructed,and designated as indicators of income,social inequality,and social equity.In multiple linear regression,the indicator of social equity was statistically significant(P<0.0001)but had a negative association,an adjusted R^(2)of 28.36%and with spatial dependence(Moran I=0.21,P=0.003455).The best model to deal with existing spatial dependence was the Spatial Lag Model.Conclusions:The better social conditions have shown progress in reducing mortality from TB,thereby reinforcing the achievement of Sustainable Development Goals.In addition,cartography was also applied,which can be replicated in other scenarios throughout the world,using a scope distinct from that of works traditionally produced in that it places the emphasis on social equity. | Mellina YAMAMURA Marcelino SANTOS NETO Francisco CHIARAVALLOTI NETO Luiz Henrique ARROYO Antonio Carlos Vieira RAMOS Ana Angelica Rego de QUEIROZ Aylana de Souza BELCHIOR Danielle Talita dos SANTOS Juliane de Almeida CRISPIM Ione Carvalho PINTO Severina Alice da Costa UCHOA Regina Celia FIORATI Ricardo Alexandre ARCENCIO | 2017 | Infectious Diseases of Poverty2017，6，1： | 0 |
| 20 | Leptin immune programming: the assembly key between birth weight and future disease?显示文摘The developmental origins for health and disease concept supports that early life environment can affect future health balance and disease.Findings suggest that birthweight(BW)can be a useful indicator of processes that influence long-term health.In fact,there is increasing evidence associating BW with later-life infections,allergy,autoimmune and cancer diseases.To date,there is no common mechanism to explain BW’s direct influence on disease expression during the life cycle.On the other hand,leptin,a circulating hormone,has been pointed as relevant in many disease pathways,including immunological and oncological,and leptin levels seem to vary directly with BW.We suggest that BW could affect early immune programming through variant early-life leptin hormone levels.It is possible that higher leptin levels in higher BW and lower leptin levels in low BW relate to a shift in Th1 and Th2 responses,accounting for different incidences of infections,allergy,autoimmune and cancers,and raising an integrative hypothesis for the effect of BW on future disease.We hope that our hypothesis concerning the possible role of early life leptin levels on immune programming and future disease can be confirmed by experimental data. | Francisco Alves de Sousa Afonso Castro Ângela Reis Rego Ana Nóbrega Pinto Miguel Bebiano Coutinho Luís Meireles | 2022 | Medical Theory and Hypothesis2022，5，4： | 0 |
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