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| 1 | Transhepatic fibrinolysis of mesenteric and portal vein thrombosis in a patient with uIterative colitis: A case report显示文摘AIM: To present a case of acute mesenteric and portal vein thrombosis treated with thrombolytic therapy in a patient with ulcerative colitis in acute phase and to review the literature on thrombolytic therapy of mesenteric-portal system. Treatment of acute portal vein thrombosis has ranged from conservative treatment with thrombolysis and anticoagulation therapy to surgical treatment with thrombectomy and/or intestinal resection.METHODS: We treated our patient with intraportal infusion of plasminogen activator and then heparin through a percutaneous transhepatic catheter.RESULTS: Thrombus resolved despite premature interruption of the thrombolytic treatment for neurological complications, which subsequently resolved.CONCLUSION: Conservative management with plasminogen activator, could be considered as a good treatment for patients with acute porto-mesenteric thrombosis. | Alfredo Guglielmi Francesca Fior Orsolya Halmos Gian Franco Veraldi Lorenzo Rossaro Andrea Ruzzenente Claudio Cordiano | 2005 | World Journal of Gastroenterology2005，11，13： | 3 |
| 2 | Role of rumination in the relationship between metacognition and shyness显示文摘AIM To explore the association between metacognitive beliefs, rumination and shyness in a non-clinical sample of adults. METHODS One hundred and three healthy subjects from the general population were enrolled in the study. Shyness was evaluated using the Revised Cheek and Buss Shyness Scale, rumination was assessed using the Ruminative Response Scale, metacognition was evaluated using the MetaCognitions Questionnaire 30, and anxiety levels were measured using the State Trait Anxiety Inventory form Y. Correlation analyses, mediation models and 95% bias-corrected and accelerated(BCaCI) bootstrapped analyses were performed. Mediation analyses were adjusted for sex and anxiety. RESULTS Shyness, rumination and metacognition were significantly correlated(P < 0.05). The relationship between metacognition and shyness was fully mediated by rumination(Indirect effect: 0.20; 95% BCaCI: 0.08-0.33).CONCLUSION These findings suggest an association between metacognition and shyness. Rumination mediated the relationship between metacognition and shyness, suggesting that rumination could be a cognitive strategy for shy people. Future research should explore the relationship between these constructs in more depth. | Sara Palmieri Giovanni Mansueto Simona Scaini Francesca Fiore Sandra Sassaroli Giovanni M Ruggiero Rosita Borlimi Bernardo J Carducci | 2018 | World Journal of Psychiatry2018，8，4： | 2 |
| 3 | Spontaneous bacterial peritonitis due to carbapenemase-producing Enterobacteriaceae:Etiology and antibiotic treatment显示文摘Carbapenem antibiotics were first introduced in the 1980s and have long been considered the most active agents for the treatment of multidrug-resistant gramnegative bacteria.Over the last decade,carbapenem-resistant Enterobacteriaceae(CRE)have emerged as organisms causing spontaneous bacterial peritonitis.Infections caused by CRE have shown a higher mortality rate than those caused by bacteria sensitive to carbapenem antibiotics.Current antibiotic guidelines for the treatment of spontaneous bacterial peritonitis are insufficient,and rapid deescalation of empiric antibiotic treatment is not widely recognized.This review summarizes the molecular characteristics,epidemiology and possible treatment of spontaneous bacterial peritonitis caused by CRE. | Marco Fiore Sveva Di Franco Aniello Alfieri Maria Beatrice Passavanti Maria Caterina Pace Stephen Petrou Francesca Martora Sebastiano Leone | 2020 | World Journal of Hepatology2020，12，12： | 1 |
| 4 | Tunable thermo-responsive hydrogels: Synthesis, structural analysis and drug release studies显示文摘 | Giuseppe Cirillo Tania Spataro Manuela Curcio U. Gianfranco Spizzirri Fiore Pasquale Nicoletta Nevio Picci Francesca Iemma | 2015 | Materials Science & Engineering C2015，，： | 1 |
| 5 | Propionyl-L-carnitine hydrochloride for treatment of mild to moderate colonic inflammatory bowel diseases显示文摘AIM:To assess clinical and endoscopic response to propionyl-L-carnitine hydrochloride(PLC) in colonic inflammatory bowel disease.METHODS:Patients suffering from mild to moderate ulcerative colitis(UC) or Crohn's disease(CD) colitis,with disease activity index(DAI) between 3 and 10 and under stable therapy with oral aminosalicylates,mercaptopurine or azathioprine,for at least 8 wk prior to baseline assessments,were considered suitable for enrollment.Fourteen patients were enrolled to assume PLC 2 g/d(two active tablets twice daily) orally.Clinical-endoscopic and histological activity were assessed by DAI and histological index(HI),respectively,following a colonoscopy performed immediately before and after 4 wk treatment.Clinical response was defined as a lowering of at least 3 points in DAI and clinical remission as a DAI score ≤ 2.Histological response was defined as an improvement of HI of at least 1 point.We used median values for the analysis.Differences pre-and post-treatment were analyzed by Wilcoxon signed rank test.RESULTS:All patients enrolled completed the study.One patient,despite medical advice,took deflazacort 5 d before follow-up colonoscopy examination.No side effects were reported by patients during the trial.After treatment,71%(SE 12%) of patients achieved clinical response,while 64%(SE 13%) obtained remission.Separating UC from CD patients,we observed a clinical response in 60%(SE 16%) and 100%,respectively.Furthermore 60%(SE 16%) of UC patients and 75%(SE 25%) of CD patients were in clinical remission after therapy.The median DAI was 7 [interquartile range(IQR):4-8] before treatment and decreased to 2(IQR:1-3)(P < 0.01) after treatment.Only patients with UC showed a significant reduction of DAI,from a median 6.5(IQR:4-9) before treatment to 2(IQR:1-3) after treatment(P < 0.01).Conversely,in CD patients,although displaying a clear reduction of DAI from 7(IQR:5.5-7.5) before therapy to 1.5(IQR:0.5-2.5) after therapy,differences observed were not significant(P = 0.06).Seventy-nine percent(SE 11%) of patients showed improvement of HI of at least 1 point,while only one CD and two UC patients showed HI stability;none showed HI worsening.Median HI decreased from 1(IQR:1-2),to 0.5(IQR:0-1) at the endoscopic control in the whole population(P < 0.01),while it changed from 1(IQR:1-2) to 0.5(IQR:0-1) in UC patients(P < 0.01) and from 1.5(IQR:1-2) to 0.5(IQR:0-1) in CD patients(P = not significant).The two sample tests of proportions showed no significant differences in clinical and histological response or in clinical remission between UC and CD patients.No side effects were reported during treatment or at 4 wk follow-up visit.CONCLUSION:PLC improves endoscopic and histological activity of mild to moderate UC.Further studies are required to evaluate PLC efficacy in colonic CD patients. | Giuseppe Merra Giovanni Gasbarrini Lucrezia Laterza Marco Pizzoferrato Andrea Poscia Franco Scaldaferri Vincenzo Arena Francesca Fiore Achille Cittadini Alessandro Sgambato Francesco Franceschi Antonio Gasbarrini | 2012 | World Journal of Gastroenterology2012，18，36： | 1 |
| 6 | Extracorporeal Shock Wave Therapy for the Treatment of Poststroke Plantar-Flexor Muscles Spasticity: A Prospective Open-Label Study显示文摘 | Andrea Santamato Maria Micello Francesco Panza Francesca Fortunato Giancarlo Logroscino Alessandro Picelli Paolo Manganotti Nicola Smania Pietro Fiore Maurizio Ranieri | 2014 | Topics in Stroke Rehabilitation2014，，1： | 1 |
| 7 | Randomized Comparison of Everolimus-Eluting Stents and Sirolimus-Eluting Stents in Patients With ST Elevation Myocardial Infarction显示文摘 | Emilio Di Lorenzo Rosario Sauro Attilio Varricchio Michele Capasso Tonino Lanzillo Fiore Manganelli Giannignazio Carbone Francesca Lanni Maria Rosaria Pagliuca Giovanni Stanco Giuseppe Rosato Harry Suryapranata Giuseppe De Luca | 2014 | JACC: Cardiovascular Interventions2014，，8： | 1 |
| 8 | Impact of a High Loading Dose of Atorvastatin on Contrast-Induced Acute Kidney Injury显示文摘 | Cristina Quintavalle Danilo Fiore Francesca De Micco Gabriella Visconti Amelia Focaccio Bruno Golia Bruno Ricciardelli Elvira Donnarumma Antonio Bianco Maria Assunta Zabatta Giancarlo Troncone Antonio Colombo Carlo Briguori Gerolama Condorelli | 2012 | Circulation2012，，25： | 1 |
| 9 | Antimicrobial approach of abdominal post-surgical infections显示文摘Abdominal surgical site infections(SSIs)are infections that occur after abdominal surgery.They can be superficial,involving the skin tissue only,or more profound,involving deeper skin tissues including organs and implanted materials.Currently,SSIs are large global health problem with an incidence that varies significantly depending on the United Nations’Human Development Index.The purpose of this review is to provide a practical update on the latest available literature on SSIs,focusing on causative pathogens and treatment with an overview of the ongoing studies of new therapeutic strategies. | Marco Fiore Antonio Corrente Sveva Di Franco Aniello Alfieri Maria Caterina Pace Francesca Martora Stephen Petrou Claudio Mauriello Sebastiano Leone | 2023 | World Journal of Gastrointestinal Surgery2023，15，12： | 0 |
| 10 | Bevacizumab maintenance in metastatic colorectal cancer: How long?显示文摘The management of patients with non-progressive metastatic colorectal cancer after six months of treatment has not yet been codified. The most relevant concerns are the effectiveness of maintenance versus discontinuation, and the tolerability of prolonged treatment. Here we report the case of a 72-year-old man affected by colorectal cancer with lung metastases who achieved a complete response after receiving capecitabine, oxaliplatin and bevacizumab for six months, and bevacizumab alone for six months. Bevacizumab was continued as maintenance regimen for more than three years. It was discontinued because of an arthroplasty. Fifty-eight months after beginning first-line treatment, the patientremains free from relapse. Adverse effects were minimal and easily controlled. | Alfonso De Stefano Roberto Moretto Chiara Alessandra Cella Francesco Jacopo Romano Lucia Raimondo Giovanni Fiore Francesca Di Pietro Stefano Pepe Sabino De Placido Chiara Carlomagno | 2014 | World Journal of Clinical Cases2014，2，11： | 0 |
| 11 | Ultra-subwavelength phase-sensitive Fano-imaging of localized photonic modes显示文摘Photonic and plasmonic devices rely on nanoscale control of the local density of optical states(LDOS)in dielectric and metallic environments.The tremendous progress in designing and tailoring the electric LDOS of nano-resonators requires an investigation tool that is able to access the detailed features of the optical localized resonant modes with deep-subwavelength spatial resolution.This scenario has motivated the development of different nanoscale imaging techniques.Here,we prove that a technique involving the combination of scanning near-field optical microscopy with resonant scattering spectroscopy enables imaging the electric LDOS in nano-resonators with outstanding spatial resolution(λ/19)by means of a pure optical method based on light scattering.Using this technique,we investigate the properties of photonic crystal nanocavities,demonstrating that the resonant modes appear as characteristic Fano line shapes,which arise from interference.Therefore,by monitoring the spatial variation of the Fano line shape,we locally measure the phase modulation of the resonant modes without the need of external heterodyne detection.This novel,deep-subwavelength imaging method allows us to access both the intensity and the phase modulation of localized electric fields.Finally,this technique could be implemented on any type of platform,being particularly appealing for those based on non-optically active material,such as silicon,glass,polymers,or metals. | Niccolo Caselli Francesca Intonti Federico La China Francesco Riboli Annamaria Gerardino Wei Bao Alexander Weber Bargioni Lianhe Li Edmund H Linfield Francesco Pagliano Andrea Fiore Massimo Gurioli | 2015 | Light(Science & Applications)2015，4，1： | 0 |
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