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| 1 | Natural orifice transluminal endoscopic surgeryvs laparoscopic ovariectomy:Complications and inflammatory response显示文摘AIM:To compare natural orifice transluminal endoscopic surgery (NOTES) vs standard laparoscopic ovariectomy in mini pigs with respect to technical aspects,complications and parameters of systemic inflammatory response.METHODS:This was a randomized,experimental,survival study.Ten female mini pigs underwent NOTES transgastric ovariectomy (NOTES group) and ten female mini pigs underwent laparoscopic ovariectomy (LAP group).A 'percutaneous endoscopic gastrostomy' approach with guidewire and sphincterotome was used for gastrotomy creation.The ovary was resected using standard biopsy forceps and a snare.The access site was closed using a 'KING' closure with a single endoloop and several clips.In the laparoscopic group,a three-port laparoscopy and an ovariectomy were performed with the use of standard laparoscopic devices.C-reactive protein (CRP),white blood count and interleukin (IL)-6 plasma levels were used as indicators of systemic inflammatory response.All animals were euthanized 28 d after surgery.RESULTS:All animals survived without complications.The mean procedure time was 41.3 min ± 17.6 min (NOTES group) and 25.7 min ± 5.25 min (LAP group,P < 0.02).Postmortem examinations demonstrated that 50% and 70% of animals were free of any complications in the NOTES and LAP groups,respectively.The remaining animals developed minor complications (adhesions) in a comparable frequency between the two groups.In the NOTES group,one animal developed a small intramural gastric abscess close to the gastrotomy site.A minor serous exudate that was present in 50% and 40% of the animals in the NOTES and laparoscopy groups,respectively,was not considered a complication.In both groups CRP levels increased significantly on the 2nd and 7th postoperative days (POD) and returned to normal after 28 d.On POD 2,an increase of CRP level was significantly higher in the NOTES group compared to the LAP group.Values of IL-6 did not differ from baseline values in either of the groups postoperatively.Interestingly,the platelet count decreased significantly on POD 2,but returned close to baseline values on POD 7 and PODs 28-30.CONCLUSION:Both NOTES and laparoscopic ovariectomies had a similar frequency of minor complications.However,the NOTES technique produced an increased systemic inflammatory response on POD 2. | Jan Martínek Ondej Ryska Tereza Filípková Radek Dolezel Stefan Juhas Jan Motlík Monika Holubová Vladimír Nosek Barbora Rotnáglová Miroslav Zavoral Miroslav Ryska | 2012 | World Journal of Gastroenterology2012，18，27： | 4 |
| 2 | Radical prostatectomy versus watchful waiting in localized prostate cancer:the Scandinavian prostate cancer group-4 randomized trial显示文摘 | Bill-Axelson A Holmberg L Filén F | | 0，，16： | 1 |
| 3 | In vitro induction of neuronal apeptosis by anti-Fas antibody-containing sera from amyotrophio lateral sclerosis patients显示文摘 | Lautrette C Vennot-Descroches C | 2000 | J Neuroimmunol2000，109，： | 1 |
| 4 | Seasonal distribution of dissolved pesticides and polynuclear aromatic hydrocarbons in the Humber Estuary and Humber coastal zone显示文摘 | Zhou J L Fil Eman T W Evans S | 1996 | Mar Poll Bull1996，32，： | 1 |
| 5 | Pain in parkinson disease: a review of the literature 显示文摘 | Fil A Cano-De-La-Cuerda R Muoz-Hellfn E | 2013 | Parkinsonism Relat Disord2013，19，3： | 1 |
| 6 | Characterization of PEDF:a multi-functional serpin family protein显示文摘 | Fil eur S Nelius T de Riese W | | 0，，05： | 1 |
| 7 | Physical and chemical properties of magnetite and magnetite-polymer nano-particles and their colloidal dispersions 显示文摘 | Zaitsev V S Fil Imonov D S Presn Ya Kov Ia | 2005 | Journal of Colloid Interface Science2005，212，1： | 1 |
| 8 | Reaching the quantum noise limit in a high-sensitivity cold-atom intertial sensor 显示文摘 | Yver-Leduc F Cheinet P Fils J | 2003 | J Opt B: Quantum Semiclass Opt2003，5，： | 1 |
| 9 | Application of magnetic resonance neurography in the evaluation of patients with peripheral nerve pathology显示文摘 | Fil er AG Kliot M Howe FA | | 0，，02： | 1 |
| 10 | Action of carbon in stress corrosion eraeking of mild steel in nitrate solution显示文摘 | J Fils | 1973 | Corrosion1973，20，1： | 1 |
| 11 | A review of the impacts of salmonid farming on marine coastal ecosystems in the southeast Pacific显示文摘 | Buschmann AH Riquelme VA Hernández-González MC Varela D Jiménez JE Henríquez LA Vergara PA Guí?ez R Filún Luis | 2006 | ICES Journal of Marine Science2006，63，7： | 1 |
| 12 | Lipoprotein-associated phospholipase A2 is elevated in patients with severe aortic valve stenosis without clinically overt atherosclerosis 显示文摘 | Kolasa-Trela R Fil K Bazanek M | 2012 | Clin Chem Lab Med2012，50，10： | 1 |
| 13 | Pain in Parkinson disease; A review of the literature显示文摘 | Ayla Fil Roberto Cano - de - la - Cuerda Elena Munoz - Hellin | 2013 | Parkinsonism and Related Disorders2013，19，： | 1 |
| 14 | Proapop totic activity of new glutathione S2 transferase inhibitors显示文摘 | Turella P CereUa C Fil omeni G | 2005 | Cancer Res2005，65，9： | 1 |
| 15 | Visualizing Lithium‐Ion Migration Pathways in Battery Materials显示文摘 | Mette ?. Fils? Michael J. Turner Gerald V. Gibbs Stefan Adams Mark A. Spackman Bo B. Iversen | 2013 | Chem Eur J2013，，46： | 1 |
| 16 | Prognostic value of computed tomography coronary angiography in patients with suspected coronary artery disease: a 24-month follow-up study显示文摘 | Annachiara Aldrovandi Erica Maffei Alessandro Palumbo Sara Seitun Chiara Martini Valerio Brambilla Alessandra Zuccarelli Giuseppe Tarantini Annick C. Weustink Nico R. Mollet Livia Ruffini Girolamo Crisi Diego Ardissino Pim J. Feyter Gabriel P. Krestin Fil | 2009 | European Radiology2009，，7： | 1 |
| 17 | Optimism and Pessimism as mediators of the relations between self-discrepancies and distress among Asian and European Americans 显示文摘 | Hardin EE Leong FIL | 2005 | J Counsel Psychol2005，52，1： | 1 |
| 18 | Stemocleidomastoidmuscle flap preventing Frey's yndrome following parotidectomy显示文摘 | FIL H O W Q DEDIVITIS R A RAPOPORT A | 2004 | World J Surg2004，28，3： | 1 |
| 19 | Control centers with open architectures显示文摘 | AZEVEDO G P OLIVERIA FIL HO A L | | 0，，04： | 1 |
| 20 | Apoptoz pri ischemii i reperfuzii miokarda显示文摘 | Gavrilenko TI Fil'chenkov AA | 2002 | Lik Sprava2002，，1： | 1 |
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