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| 1 | Evaluation of inflammatory activity in Crohn's disease and ulcerative colitis显示文摘Crohn's disease and ulcerative colitis evolve with a relapsing and remitting course.Determination of inflammatory state is crucial for the assessment of disease activity and for tailoring therapy.However,no simple diagnostic test for monitoring intestinal inflammation is available.Noninvasive markers give only indirect assessments of disease activity.Histopathological or endoscopical examinations accurately assess inflammatory activity,but they are invasive,time consuming and expensive and therefore are unsuitable for routine use.Imaging procedures are not applicable for ulcerative colitis.The usefulness of ultrasound and Doppler imag-ing in assessing disease activity is still a matter of discussion for Crohn's disease,and an increased interest in computed tomography enterograph (CTE) has been seen,mainly because it can delineate the extent and severity of bowel wall inflammation,besides detecting extraluminal findings.Until now,the available data concerning the accuracy of magnetic resonance enterography in detecting disease activity is less than CTE.Due to this,clinical activity indices are still commonly used for both diseases. | Eduardo Garcia Vilela Henrique Osvaldo da Gama Torres Fabiana Paiva Martins Maria de Lourdes de Abreu Ferrari Marcella Menezes Andrade Aloísio Sales da Cunha | 2012 | World Journal of Gastroenterology2012，18，9： | 23 |
| 2 | Different risk factors influence peptic ulcer disease development in a Brazilian population显示文摘AIM: To investigate age, sex, histopathology and Helicobacter pylori (H. pylori) status, as risk factors for gastroduodenal disease outcome in Brazilian dyspeptic patients.tients submitted to upper gastroscopy at Hospital das Clinicas of Marilia, antral biopsy specimens were obtained and subjected to histopathology and H. pylori diagnosis. All patients presenting chronic gastritis (CG) and peptic ulcer (PU) disease localized in the stomach, gastric ulcer (GU) and/or duodenal ulcer (DU) were included in the study. Gastric biopsies (n = 668) positive for H. pylori by rapid urease test were investigated for vacuolating cytotoxin A (vacA ) medium (m) region mosaicism by polymerase chain reaction. Logistic regression analysis was performed to verify the association of age, sex, histopathologic alterations, H. pylori diagnosis and vacA m region mosaicism with the incidence of DU, GU and CG in patients. RESULTS: Of 1466 patients submitted to endoscopy, 1060 (72.3%) presented CG [male/female = 506/554; mean age (year) ± SD = 51.2 ± 17.81], 88 (6.0%) presented DU [male/female = 54/34; mean age (year) ± SD = 51.4 ± 17.14], and 75 (5.1%) presented GU [male/female = 54/21; mean age (year) ± SD = 51.3 ± 17.12] and were included in the comparative analysis. Sex and age showed no detectable effect on CG incidence (overall c 2 = 2.1, P = 0.3423). Sex [Odds ratios (OR) = 1.8631, P = 0.0058] but not age (OR = 0.9929, P = 0.2699) was associated with DU and both parameters had a highly significant effect on GU (overall c 2 = 30.5, P < 0.0001). The histopathological results showed a significant contribution of ageing for both atrophy (OR = 1.0297, P < 0.0001) and intestinal metaplasia (OR = 1.0520, P < 0.0001). Presence of H. pylori was significantly associated with decreasing age (OR = 0.9827, P < 0.0001) and with the incidence of DU (OR = 3.6077, P < 0.0001). The prevalence of m1 in DU was statistically significant (OR = 2.3563, P = 0.0018) but not in CG (OR = 2.678, P = 0.0863) and GU (OR = 1.520, P = 0.2863). CONCLUSION: In our population, male gender was a risk factor for PU; ageing for GU, atrophy and metapla-sia; and H. pylori of vacA m1 genotype for DU. | Rodrigo Buzinaro Suzuki Rodrigo Faria Cola Larissa Tranquilino Bardela Cola Camila Garcia Ferrari Fred Ellinger Altino Luiz Therezo Luis Carlos da Silva André Eterovic Márcia Aparecida Sperana | 2012 | World Journal of Gastroenterology2012，18，38： | 8 |
| 3 | Dietary approach in the treatment of nonalcoholic fatty liver disease显示文摘Nonalcoholic fatty liver disease(NAFLD) has been identified as one of the most prevalent chronic liver disease in adults and children populations. NAFLD is usually associated with the metabolic syndrome(MS), which is chiefly related to insulin resistance and its consequences. Insulin resistance has a crucial role in the pathogenesis of hepatic steatosis and potentially nonalcoholic steatohepatitis(NASH). Because of the contemporary epidemics of MS and obesity, the burden of NAFLD is also expected to rise. Unhealthy diets, such as the so-called western diet, are enriched in fructose, trans-fatty acids and saturated fat and seem to be associated with the development of NAFLD. In human studies, certain dietary sugars, particularly fructose, are used as a substrate for lipogenesis leading to hepatic fatty infiltration, inflammation, and possibly fibrosis. Other investigations have shown that fat consumption especially cholesterol and trans/saturated fatty acids are also steatogenic and seem to increase visceral adiposity. The identification of specific dietary components that favor the development of NASH could be important for the management of this disorder. This review focuses on the effects of different dietary approaches to prevent and treat NAFLD emphasizing the macronutrients and energy composition. | Silvia Marinho Ferolla Luciana Costa Silva Maria de Lourdes Abreu Ferrari Aloísio Sales da Cunha Flaviano dos Santos Martins Cláudia Alves Couto Teresa Cristina Abreu Ferrari | 2015 | World Journal of Hepatology2015，7，24： | 2 |
| 4 | Surface ex- pression patterns of negative regulatory molecules identify determinants of virus-specific CD8 T-cell exhaustion in HIV infection 显示文摘 | Yamamoto T Price DA Casazza JP Ferrari G Nason M Chattopadhyay PK Roederer M Gostick E Katsikis PD Douek DC Haubrich R Petrovas C Koup RA | 2011 | Blood2011，117，18： | 1 |
| 5 | Dental arch dimensions in class II division I maloeelu- sions with mandibular deficiency 显示文摘 | da Silva Filho OG Ferrari Jfmior FM Okada Ozawa T | 2008 | Angle Orthod2008，78，3： | 1 |
| 6 | The successful management of portal vein thrombosis after hepatic transplantation with a splenorenal shunt显示文摘 | Rouch DA Emond JC Ferrari M | 1988 | Surg Gynecol Obstet1988，166，： | 1 |
| 7 | Influence of canine brain decomposition on laboratory diagnosis of rabies显示文摘 | Albas A Ferrari CI da Silva LH | 1999 | Rev Soc Bras Med Trop1999，32，1： | 1 |
| 8 | When to Perform Bone Scan in Patients with Newly Diagnosed Prostate Cancer: External Validation of the Currently Available Guidelines and Proposal of a Novel Risk Stratification Tool 显示文摘 | Alberto Briganti Niccolò Passoni Matteo Ferrari Umberto Capitanio Nazareno Suardi Andrea Gallina Luigi Filippo Da Pozzo Maria Picchio Valerio Di Girolamo Andrea Salonia Liugi Gianolli Cristina Messa Patrizio Rigatti Francesco Montorsi | 2009 | European Urology2009，，4： | 1 |
| 9 | Posterior ossification of the shoulder: The Bennett lesion--etiology, diagnosis, and treatment显示文摘 | Ferrari JD Ferrari DA Coumas J | 1994 | The American Journal of Sports Meddicine1994，22，： | 1 |
| 10 | Effects of graded hypotension on cerebral blood flow, blood volume, and mean transit time in dogs显示文摘 | Wilson DA Hanley DF | 1992 | Am J Physiol1992，262，6： | 1 |
| 11 | Oxidative stability of biodiesel from soybeanoil fatty acid ethyl esters显示文摘 | ROSELI AP FERRARI VANESSA DA SILVA OLIVEIRA ARDALLA SCABIO | 2005 | Scientia agricola2005，62，6： | 1 |
| 12 | Dental arch dimensions in class II division 1 malocclusions with mandibular deft- cieney 显示文摘 | Da Silva Filho OG Ferrari Jfinior FM Okada Ozawa T | 2008 | Angle Orthod2008，78，3： | 1 |
| 13 | Influence of Saccharomyces boulardii on the intestinal permeability of patients with Crohn′s disease in re-mission显示文摘 | Garcia Vilela E De Lourdes De Abreu Ferrari M Oswaldo Da Gama Torres H | | 0，，07： | 1 |
| 14 | Quaternary Ammonium Salts Immobilized on Silica Gel: Exchange Properties and Application as Potentiometric Sensor for Perchlorate Ions显示文摘 | Elvio A. de Campos Antonio A. da Silva Alfaya Rosilene T. Ferrari Creusa Maieru M. Costa | 2001 | Journal of Colloid And Interface Science2001，，1： | 1 |
| 15 | Dental arch dimensions in class II division 1 malocclusions with mandibular deficiency显示文摘 | da Silva Filho OG Ferrari Jfinior FM Okada Ozawa T | 2008 | Angle Orthod2008，78，3： | 1 |
| 16 | Laryngeal cleft repair:the an- esthetic perspective显示文摘 | Lynne R Ferrari Da Zurakowski J | 2013 | Paediatric anaesthesia2013，23，4： | 1 |
| 17 | Anomalous origin of the left eoronary artery from the pulmonary artery in adulthood on CT and MRI 显示文摘 | Khanna A Torigian DA Ferrari VA | 2005 | Am J Roentgenol2005，185，2： | 1 |
| 18 | Arthroscopic evaluation of the popliteus:clues to posterolateral laxity显示文摘 | Ferrari DA | 2005 | Arthroscopy2005，21，6： | 1 |
| 19 | Photother- apy with low-level laser affects the remodeling of types I and HI collagen in skeletal muscle repair显示文摘 | de Souza TO Mesquita DA Ferrari RA | 2011 | Lasers Med Sci2011，26，： | 1 |
| 20 | Unilateral Hand-Foot Syndrome:Does It Take Sides?Case Report and Literature Review显示文摘 | Livia Almeida da Cruz Paulo Marcelo Gehm Hoff Claudio Luiz Seabra Ferrari | 2012 | Clinical Colorectal Cancer2012，，82： | 1 |
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