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391篇 您的检索式:作者名="Wilson DA"
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1Feasibility and safety of autologous bone marrow mononuclear cell transplantation in patients with advanced chronic liver disease显示文摘AIM: To evaluate the safety and feasibility of bone marrow cell (BMC) transplantation in patients with chronic liver disease on the waiting list for liver transplantation. METHODS: Ten patients (eight males) with chronic liver disease were enrolled to receive infusion of autologous bone marrow-derived cells. Seven patients were classified as Child-Pugh B and three as Child-Pugh C. Baseline assessment included complete clinical and laboratory evaluation and abdominal MRI. Approximately 50 ml of bone marrow aspirate was prepared by centrifugation in a ficoll-hypaque gradient. At least of 100 millions of mononuclear-enriched BMCs were infused into the hepatic artery using the routine technique for arterial chemoembolization for liver tumors. Patients were followed up for adverse events up to 4 mo. RESULTS: The median age of the patients was 52 years (range 24-70 years). All patients were discharged 48 h after BMC infusion. Two patients complained ofmild pain at the bone marrow needle puncture site. No other complications or specific side effects related to the procedure were observed. Bilirubin levels were lower at 1 (2.19 ± 0.9) and 4 mo (2.10 ± 1.0) after cell transplantation that baseline levels (2.78 ± 1.2). Albumin levels 4 mo after BMC infusion (3.73 ± 0.5) were higher than baseline levels (3.47 ± 0.5). International normalized ratio (INR) decreased from 1.48 (SD = 0.23) to 1.43 (SD = 0.23) one month after cell transplantation. CONCLUSION: BMC infusion into hepatic artery of patients with advanced chronic liver disease is safe and feasible. In addition, a decrease in mean serum bilirubin and INR levels and an increase in albumin levels are observed. Our data warrant further studies in order to evaluate the effect of BMC transplantation in patients with advanced chronic liver disease.Andre Castro lyra Milena Botelho Pereira Soares luiz Flavio Maia da Silva Marcos Fraga Fortes André Goyanna Pinheiro Silva Augusto César de Andrade Mota Sheilla A Oliveira Eduardo lorens Braga Wilson Andrade de Carvalho Bernd Genser Ricardo Ribeiro dos Santos luiz Guilherme Costa lyra 2007World Journal of Gastroenterology2007,13,7:21
2Development of Junction Elements from Study of the Bionics显示文摘The applications of bionic methodology developed by the Laboratory of Design and Material Selection as basis in the creation of junction elements were demonstrated. These elements favor the application of Ecodesign in reference to the effec-tiveness of product dismount aiming the reduction of ambient impact in all its phases of use. The creation,the development and the confection of new junction elements were described,and case studies of new products developed specifically with this purpose were presented.Wilson Kindlein Junior Luis Henrique Alves Cndido André Canal Marques Sandra Souza dos Santos Maurício da Silva Viegas 2007Journal of Bionic Engineering2007,4,1:2
3Fracture stabilization of proximal tibial fractures with the proximal tibial LISS:early experi- ence in Birmingham,Alabama (USA)显示文摘Stannard JP Wilson TC Volgas DA et a/ 2003Injury2003,34,1:1
4No evidence for anischemic penumbra in massive experimental intracerebral hemorrhage显示文摘Qureshi AI Wilson DA Hanley DF 1999Neurology1999,52,:1
5Listeria moncytogenes infection and activation of human brain microvascular endothelial cells显示文摘Wilson SL Drevets DA 1998J Infect Dis1998,178,:1
6Dramatic decline in circulating intercellular adhesion molecule-1 concentration on quitting tobacco smoking 显示文摘Scott DA Staoleton JA Wilson RF 2000Blood Cells Mol Dis2000,26,3:1
7Diversity and antimicrobial activities of surface-attached marine bacteria from Sydney Harbour, Australia 显示文摘Wilson GS Raftos DA Corrigan SL 2010Microbiol Res2010,165,4:1
8Factors regulating collagen synthesis and degradation during second-intention healing of wounds in the thoracic region and the distal aspect of the forelimb of horses显示文摘Schwartz AJ Wilson DA Weber KT 2002Am J Vet Res2002,63,11:1
9An in vitro evaluation of the antimicrobial efficacy of irrigants on biofilms of root canal isolates显示文摘Spratt DA Pratten J Wilson M 2001Inter End J2001,34,:1
10Transient white matter changes on MR images in children undergoing chemotherapy for acute lymphcytic leukemia: correlation with neuropsychologic deficiencies显示文摘 Nitschke R Bowman ME 1991Radiology1991,180,:1
11The fundamental role of memory in olfactory perception 显示文摘Wilson DA Stevenson RJ 2003Trends Neurosci2003,26,:1
12Apolipoprotein E-4 allele,AD pathology,and the clinical expression of Alzheimer's disease显示文摘Bennett DA Wilson RS Schneider JA 2003Neurology2003,60,:1
13Prediction of coronary heart disease using risk factor categories显示文摘Wilson PW Gostino DA Levyd RB 1998Circulation1998,97,:1
14Androgen receptor expression in the developing rat prostate is not altered by castration,flutamide,or suppression of the adrenal axis显示文摘Husmann DA Mcphaul M J Wilson JD 1991Endocrinology1991,128,4:1
15Multicenter evaluation of a Candida albicans peptide nucleic acid fluorescent in situ hybridization probe for characterization of yeast isolates from blood cultures显示文摘Wilson DA Joyce M J Hall LS 2005J Clin Microbiol2005,43,6:1
16Clinical diagnosis of Bi-nswanger's disease显示文摘Bennett DA Wilson RS Gilley DW 1990J Neurosurg Psychiatry1990,53,11:1
17Microvascular changes explainthe “Two- hit” theory of multiple organ failure显示文摘Garrison RN Spain DA Wilson MA 1998Ann Surg1998,227,:1
18Radiologic characteristics and resul of surgical management of Rathke's cysts in 43 patients显示文摘Ross DA Norman D Wilson CB 1992Nearosurgery1992,30,2:1
19Pharmacological reduction of mean arterial pressure does not adversely effect regional cerebral blood flow and intracranial pressure in experimental intracerebral hemorrhage显示文摘 Wilson DA Hanley DF 1999Crit Care Med1999,27,:1
20Propofol-induced bradycardia in a pediatric patient undergoing chemotherapy with the known cardiotoxic agent cytarabin 显示文摘Wilson SE Boyack DA Ezeife-Ugorji OC 2006Paediatr Anaesth2006,16,6:1
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