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| 1 | Lithium polyacrylate as a binder for tin-cobalt-carbon negative electrodes in lithium-ion batteries显示文摘 | Li J Le D B Ferguson P P | | 0，，08： | 1 |
| 2 | Influence of the severity of cognitive impairment on the effect of the ginkgo biloba extract EGb761 in Alzheimer's disease显示文摘 | Le Bars PL Velascob FM Fergusone JM | 2002 | Neuropschobiol2002，45，1： | 1 |
| 3 | Observing three-dimensional human microvascular and myogenic architecture using conventional fluorescence microscopy显示文摘 | Hamid SA Ferguson LE McGavigan CJ | 2006 | Micron2006，37，2： | 1 |
| 4 | Influence of the severity of congnitive impairment on the effect of the Ginko biloba extract Egb761 in Alzheimer's disease显示文摘 | Le Bars PL Velesco FM Ferguson JM | 2002 | Neuropsychobiology2002，45，： | 1 |
| 5 | Influence of the severity of Cognitive impairment on the effect of the Gnkgo biloba extract Egb 761 in Alzheimer's disease 显示文摘 | Le Bats PL Velaseo FM Ferguson JM | 2002 | Neuropsychobiology2002，45，1： | 1 |
| 6 | Influence of the Severity of Cognitive Impairment on the Effect of the Gnkgo Biloba Extract Egb 761 in Alzheimer' s Disease 显示文摘 | LE BARS PL VELASCO FM FERGUSON JM | 2002 | Neuropsychobiology ( S0302-282X)2002，45，1： | 1 |
| 7 | ^(68)Ga-PSMA PET/CT versus CT and bone scan for investigation of PSA failure post radical prostatectomy显示文摘Objective:To evaluate the use of Gallium-68 prostate-specific membrane antigen positron emission tomography/computed tomography(^(68)Ga-PSMA PET/CT),compared with conventional CT abdomen/pelvis(CTAP)and whole body single photon emission CT bone scan(BS),for detection of local or distant metastasis following biochemical failure/recurrence in post-prostatectomy patients.Methods:We conducted a review of our prospectively maintained,institutional database to identify 384 patients with post-prostatectomy biochemical failure/recurrence who underwent PSMA PET/CT,CTAP and BS from February 2015 to August 2017 in Nepean Hospital,tertiary referral centre.The results of the three imaging modalities were analysed for their ability to detect local recurrence and distant metastases.PSMA PET/CT and CTAP imaging were separately performed on the same day and the BS was performed within several days(mostly in 24 h).Difference in detection rates was determined between the modalities and the Chi square test was used to determine significance.Results:A total of 384 patients were identified with a median prostate-specific antigen(PSA)of 0.465 ng/mL(interquartile range =0.19-2.00 ng/mL).Overall,PSMA PET/CT was positive for 245(63.8%)patients whereas CTAP and BS were positive in 174 patients(45.3%).A total of 98 patients(25.5%)had local or distant metastasis detected on PSMA only,while 20 patients(5.2%)had recurrences detected on CTAP but not on PSMA PET/CT.Conclusion:The use of PSMA PET/CT has a higher detection rate of predicted local or distant metastasis compared to CTAP and BS in the staging of patients with biochemical recurrences after radical prostatectomy. | Yuigi Yuminaga Chris Rothe Jonathan Kam Kieran Beattie Mohan Arianayagam Chuong Bui Bertram Canagasingham Richard Ferguson Mohamed Khadra Raymond Ko Ken Le Diep Nguyen Celi Varol Matthew Winter | 2021 | Asian Journal of Urology2021，8，2： | 1 |
| 8 | Butterfly genome reveals promiscuous exchange of mimicry adaptations among species显示文摘 | Dasmahapatra KK Walters JR Briscoe AD Davey JW Whibley A Nadeau N J Zimin AV Hughes DST Ferguson LC Martin SH Salazar C Lewis JJ Adler S Ahn S J Baker DA Baxter SW Chamberlain NL Chauhan R Counterman BA Dalmay T Gilbert LE Gordon K Heckel DG Hines HM Hoff | | 0，，： | 1 |
| 9 | Effec ts of exercise training and its cessation on components of the insulin resistance syndrome in obese children显示文摘 | Ferguson MA Gutin B Le NA | 1999 | Int J Obes Relat Metab Disord1999，23，8： | 1 |
| 10 | Influence of the severity of Cognitive impairment on the effect of the Gnkgo biloba extract Egb 761 in Alzheimer's disease 显示文摘 | Le Bars Pl Velasco FM Ferguson JM | 2002 | Neuropsychobiology2002，45，1： | 1 |
| 11 | Effects of exercise training and its cessation on components of the insulin resistance syndrome in obese children显示文摘 | Ferguson MA Gutin B Le NA | 1999 | Int J Obes Relat Metab Disord1999，23，8： | 1 |
| 12 | Lithium polyacrylate as a binder for tin-cobalt-carbon negative electrodes in lithium-ion batteries 显示文摘 | Li J Le D B Ferguson P P | 2010 | Electrochimica Acta2010，55，8： | 1 |
| 13 | Influence of the severity of cognitive impairment on the effect of the Gnkgo biloba extract EGb 761 in Alzheimer's disease显示文摘 | Le Bars PL Velasco FM Ferguson JM | 2002 | Neuropsychobiology2002，45，1： | 1 |
| 14 | Disrupted Maturation of Prefrontal Layer 5 Neuronal Circuits in an Alzheimer’s Mouse Model of Amyloid Deposition显示文摘Mutations in genes encoding amyloid precursor protein(APP)and presenilins(PSs)cause familial forms of Alzheimer’s disease(AD),a neurodegenerative disorder strongly associated with aging.It is currently unknown whether and how AD risks affect early brain development,and to what extent subtle synaptic pathology may occur prior to overt hallmark AD pathology.Transgenic mutant APP/PS1 over-expression mouse lines are key tools for studying the molecular mechanisms of AD pathogenesis.Among these lines,the 5XFAD mice rapidly develop key features of AD pathology and have proven utility in studying amyloid plaque formation and amyloidβ(Aβ)-induced neurodegeneration.We reasoned that transgenic mutant APP/PS1 over-expression in 5XFAD mice may lead to neurodevelopmental defects in early cortical neurons,and performed detailed synaptic physiological characterization of layer 5(L5)neurons from the prefrontal cortex(PFC)of 5XFAD and wild-type littermate controls.L5 PFC neurons from 5XFAD mice show early APP/Aβimmunolabeling.Whole-cell patch-clamp recording at an early post-weaning age(P22–30)revealed functional impairments;although 5XFAD PFC-L5 neurons exhibited similar membrane properties,they were intrinsically less excitable.In addition,these neurons received smaller amplitude and frequency of miniature excitatory synaptic inputs.These functional disturbances were further corroborated by decreased dendritic spine density and spine head volumes that indicated impaired synapse maturation.Slice biotinylation followed by Western blot analysis of PFC-L5 tissue revealed that 5XFAD mice showed reduced synaptic AMPA receptor subunit GluA1 and decreased synaptic NMDA receptor subunit GluN2A.Consistent with this,patch-clamp recording of the evoked L23>L5 synaptic responses revealed a reduced AMPA/NMDA receptor current ratio,and an increased level of AMPAR-lacking silent synapses.These results suggest that transgenic mutant forms of APP/PS1 overexpression in 5XFAD mice leads to early developmental defects of cortical circuits,which could contribute to the age-dependent synaptic pathology and neurodegeneration later in life. | Chang Chen Jing Wei Xiaokuang Ma Baomei Xia Neha Shakir Jessica K.Zhang Le Zhang Yuehua Cui Deveroux Ferguson Shenfeng Qiu Feng Bai | 2023 | Neuroscience Bulletin2023，39，6： | 0 |
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