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| 1 | Application of bioactive hydrogels combined with dental pulp stem cells for the repair of large gap peripheral nerve injuries显示文摘Due to the limitations in autogenous nerve grafting or Schwann cell transplantation,large gap peripheral nerve injuries require a bridging strategy supported by nerve conduit.Cell based therapies provide a novel treatment for peripheral nerve injuries.In this study,we first experimented an optimal scaffold material synthesis protocol,from where we selected the 10%GFD formula(10%GelMA hydrogel,recombinant human basic fibroblast growth factor and dental pulp stem cells(DPSCs))to fill a cellulose/soy protein isolate composite membrane(CSM)tube to construct a third generation of nerve regeneration conduit,CSM-GFD.Then this CSM-GFD conduit was applied to repair a 15-mm long defect of sciatic nerve in a rat model.After 12 week post implant surgery,at histologic level,we found CSM-GFD conduit could regenerate nerve tissue like neuron and Schwann like nerve cells and myelinated nerve fibers.At physical level,CSM-GFD achieved functional recovery assessed by a sciatic functional index study.In both levels,CSM-GFD performed like what gold standard,the nerve autograft,could do.Further,we unveiled that almost all newly formed nerve tissue at defect site was originated from the direct differentiation of exogeneous DPSCs in CSM-GFD.In conclusion,we claimed that this third-generation nerve regeneration conduit,CSM-GFD,could be a promising tissue engineering approach to replace the conventional nerve autograft to treat the large gap defect in peripheral nerve injuries. | Lihua Luo Yan He Ling Jin Yanni Zhang Fernando P.Guastaldi Abdullkhaleg A.Albashari Fengting Hu Xiaoyan Wang Lei Wang Jian Xiao Lingli Li Jianming Wang Akon Higuchi Qingsong Ye | 2021 | Bioactive Materials2021，6，3： | 11 |
| 2 | Preparation and application of amino functionalized mesoporous nanofiber membrane via electrospinning for adsorption of Cr^(3+) from aqueous solution显示文摘Novel amino(-NH 2) functionalized mesoporous polyvinyl pyrrolidone(PVP)/SiO 2 composite nanofiber membranes were fabricated by a one-step electrospinning method using poly(vinyl alcohol) and tetraethyl orthosilicate(TEOS) mixed with cationic surfactant,cetyltrimethyl ammonium bromide(CTAB) as the structure directing agent.Ureidopropyltriethoxysilane was used for functionalization of the internal pore surfaces.The membranes were characterized by scanning electron microscopy(SEM),high-resolution transmission electron microscopy(HRTEM) images,X-ray diffraction(XRD),Fourier-transform infrared spectroscopy(FT-IR),element analyzer and N 2 adsorption-desorption isotherms.The nanofiber diameters,average pore diameters and surface areas were 100-700 nm,2.86 nm and 873.62 m 2 /g,respectively.These mesoporous membranes functionalized with-NH 2 groups exhibited very high adsorptions properties based on the adsorption of Cr 3+ from an aqueous solution.Equilibrium adsorption was achieved after approximately 20 min and more than 97% of chromium ions in the solution were removed.The membrane could be regenerated through acidification. | Ahmed A.Taha Junlian Qiao Fengting Li Bingru Zhang | 2012 | Journal of Environmental Sciences2012，24，4： | 6 |
| 3 | Preparation of monolayer-assembled fluorescent film and its sensing performances to hidden nitroaromatic explosives显示文摘Pyrene was chemically assembled on a glass plate surface in a monolayer manner via spacers con-taining triethylenetetramine (TETA) subunits. It has been demonstrated that the fluorescence emission of the film is sensitive to the presence of trace amount of nitroaromatic compound (NAC) vapors. As discovered in the present work, the response selectivity of the pyrene-functionalized film depends on the length of the spacer, the vapor pressure of a given NAC, and the quencher size. The film shows faster response to those quenchers which have higher vapor pressure and smaller size. Compared to the film with shorter spacers, the present film with longer flexible spacers shows a slower response to the NACs, but higher selectivity to the quencher size. Additionally, the detection limits to common ex-plosives in vapor phase, 2,4,6-trinitrotoluene (TNT) and 2,4-dinitrotoluene (DNT), are 7.14×10-12 and 5.49×10-11 g·mL-1, respectively. Further examinations indicated that the sensing process is fully re-versible, and the vapors of those common interference such as benzene, toluene, ethanol, and perfume have little effect upon the sensing performances of the film. | LI HuiHui LU FengTing ZHANG ShuJuan HE Gang FANG Yu | 2008 | Chinese Science Bulletin2008，53，11： | 4 |
| 4 | Expression profiles of miRNAs in human pancreatic cancer cell lines显示文摘目的将开始由微数组技术在人的胰腺的癌症房间线分析 miRNAs 表示侧面的差别。743 根探针全部的方法 A 根据人,老鼠,和老鼠的已知的 miRNAs 序列被设计。miRNAs 微数组被生产,它的可靠被验证。全部的 RNA 被提取, miRNAs 与胰腺的癌症房间衬里的人(SW1990, Capan-2, BxPC-3, Aspc-1,和 Panc1 ) 和不朽的人被分开胰腺的管上皮的房间线 H6C7。他们用 T4 RNA ligase 被标记,当时是有微数组的 hybridized。通过数组扫描和分析,在胰腺的癌症的 miRNAs 表达式侧面被获得。结果被北弄污和 RT-PCR 验证。与胰腺的癌症有关的 63 miRNAs 全部的结果 A 被发现是在 5 根胰腺的癌症房间线表示的差别,包括 25 下面调整并且 38 起来调整的 miRNAs。mir-21 和 let-7 的表情也被证实。结果建议了侧面能在胰腺的癌症房间被发现的那 miRNAs 表情的结论。 | Shineng Zhang Haijun Zuo Zhong Yu Fengting Huang Wa Zhong | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，2： | 3 |
| 5 | Living Bacteria-Mediated Aerobic Photoinduced Radical Polymerization for in Situ Bacterial Encapsulation and Differentiation显示文摘Conventional polymerizations mediated by living cells typically require synthetic transition-metal complexes or photoredox catalysts.Herein,we report an alternative photoinduced polymerization strategy for preparing functional polymer hydrogels through bacteria-initiated radical polymerization of acrylamides in ordinary culture media.Upon light irradiation under ambient conditions,polyacrylamides were obtained with molecular weights of over 150 kDa using various bacteria. | Huan Lu Yiming Huang Fengting Lv Libing Liu Yuguo Ma Shu Wang | 2021 | CCS Chemistry2021，3，7： | 2 |
| 6 | Capillary bridges and capillary forces between two axisymmetric power-law particles显示文摘 | Lefeng Wang Fengting Su Huichao Xu Weibin Rong Hui Xie | 2016 | Particuology2016，14，4： | 2 |
| 7 | Hierarchical porous induced competent removal of low concentration azo dye molecules by generating a leachy crystalline structure H-MIL-53(Fe)显示文摘The development in technology of synthetic azo dyes,has led to excessive water resources pollution.Eve n at lower concentration they can impart the quality of water and human life.Herein,we have developed a novel synthesis strategy via introducing salicylic acid(SA)for the synthesis of a leachy crystalline material H-MIL-53(Fe)with hierarchical pores(HP)and exposed coordination unsaturated sites(CUS),which had higher surface area and larger pore volume than the as synthesized MIL-53(Fe).Due to these characteristics,H-MIL-53(Fe)was competent removal of orange G(OG,one of the frequently used azo dyes)with equilibrium in 300 min and the maximum adsorption capacity of 163.9 mg/g.The adsorption mechanism of OG onto H-MIL-53(Fe)was mostly based on electrostatic attraction between CUS of HMIL-53(Fe)along with HP as active species to OG diffusion and bind.By comparing H-MIL-53(Fe)with other adsorbents for OG adsorption,it is undoubtedly that H-MIL-53(Fe)can be used as a promising adsorbent for OG removal from aqueous solutions. | Tao Feng Jean Pierre Bavumiragira Mumbi Anne Wambui Daniel Manaye Kabtamu Krisztina László Ying Wang Fengting Li | 2020 | Chinese Chemical Letters2020，31，10： | 2 |
| 8 | Selective electroreduction of nitrate to ammonia via NbWO_(6)perovskite nanosheets with oxygen vacancy显示文摘Electrocatalytic nitrate reduction to ammonia(NRA)under ambient conditions is significant for carbonneutral synthetic fuels.Nevertheless,the lack of efficient electrocatalysts with tunable nanostructure for NRA remains a grand challenge.Herein,Nb WO_(6)nanosheets with oxygen vacancy(NbWO_(6-x))was demonstrated via thermal treatment and exfoliation with NH_(3)selectivity of 86.8%and Faradaic efficiency of85.7%toward NRA.^(1)H nuclear magnetic resonance spectra coupled with^(15)N isotope labeling experiments proved that NH_(3)originated from NO_(3)^-.The function of oxygen vacancy was revealed by computational studies in NRA.Moreover,the reaction mechanism and pathway of NRA could be deduced based on the results of online differential electrochemical mass spectrometry(DEMS).This work provides a selective NH_(3)generation strategy to decarbonize the energy-chemical sector,bridging the gap between batteries and biofuels. | Tao Feng Fengting Li Xiaojun Hu Ying Wang | 2023 | Chinese Chemical Letters2023，34，5： | 2 |
| 9 | SNR Improvement of QEPAS System by Preamplifier Circuit Optimization and Frequency Locked Technique显示文摘前置放大器电路噪音在石英是很重要的提高的 photoacoustic 光谱学(QEPAS ) 系统。在这份报纸,几噪音来源详细被评估并且讨论。基于噪音特征,相应噪音减小方法被建议。另外,频率锁住技术被介绍进一步优化 QEPAS 系统噪音并且改进信号,它比常规频率扫描方法完成更好的表演。作为结果, signal-to-noise 比率(SNR ) 能被利用频率增加 14 次在为水的 QEPAS 系统的锁的技术和数字平均技术蒸汽察觉。 | Qinduan ZHANG Jun CHANG Zongliang WANG Fupeng WANG Fengting JIANG Mengyao WANG | 2018 | Photonic Sensors2018，8，2： | 2 |
| 10 | Specific Responses of Soil Microbial Residue Carbon to Long-Term Mineral Fertilizer Applications to Reddish Paddy Soils显示文摘Mineral nutrient inputs to soil may alter microbial activity and consequently influence the accumulation of microbial residues. In this study, we investigated the effects of application rates and ratios of mineral fertilizers on the microbial residue carbon(MRC) of reddish paddy soils after long-term(15-year) fertilizer applications in southern China. Contents of three soil amino sugars as microbial residue contents were determined and MRC were calculated based on amino sugars. Results showed that three individual amino sugar contents increased as fertilizer application rates increased until maximum values were reached at a rate of 450-59-187 kg ha^(-1) year^(-1)(N-P-K). The three amino sugar contents then declined significantly under the highest mineral fertilizer application rate of 675-88-280 kg ha^(-1) year^(-1)(N-P-K). In addition, to enhance the microbial residue contents, it was more beneficial to double P(N:P:K= 1:0.26:0.41) in fertilizers applied to the P-deficient reddish paddy soils than to double either N(N:P:K = 2:0.13:0.41) or K(N:P:K= 1:0.13:0.82). The contents of the three individual amino sugars and microbial residues under different fertilizer application rates and ratios were significantly and positively correlated with soil organic carbon(SOC), total N, total P, and p H. Increases in values of the fungal C to bacterial C ratios showed that soil organic matter(SOM) stability increased because of the fertilizer applications over the past 15 years. The contents and ratios of amino sugars can be used as indicators to evaluate the impact of mineral fertilizer applications on SOM dynamics in subtropical paddy soils. The results indicated that fertilizer applications at a rate of 450-59-187 kg ha^(-1) year^(-1)(N-P-K) may improve crop yields, SOC contents, and SOC stability in subtropical paddy soils. | ZHANG Xinyu XIE Juan YANG Fengting DONG Wenyi DAI Xiaoqin YANG Yang SUN Xiaomin | 2018 | Pedosphere2018，28，3： | 2 |
| 11 | Conjugated Polymer Nanomaterials for Phototherapy of Cancer显示文摘Due to the excellent properties including high specificity,low side-effect and good biocompatibility,conjugated polymer nanomaterials have been served as efficient anticancer reagents in die past decades.According to the developed anticancer systems based on conjugated polymer nanomaterials,it could be summarized into three main cancer therapy strategies:photodynamic therapy(PDT),photothermal therapy(PTT)and combination therapy.In this mini review,we provide a brief introduction to three different cancer therapy modes,their mechanisms and potential biological applications.Furthermore,some perspectives on the further development of conjugated polymer nanomaterials are proposed in the territory of anticancer precision medicine. | FU Xuancheng BAI Haotian LYU Fengting LIU Libing WANG Shu | 2020 | Chemical Research in Chinese Universities2020，36，2： | 2 |
| 12 | Preparation and application of functionalized cellulose acetate/silica composite nanofibrous membrane via electrospinning for Cr(VI) ion removal from aqueous solution显示文摘 | Ahmed A. Taha Yi-na Wu Hongtao Wang Fengting Li | 2012 | Journal of Environmental Management2012，，： | 2 |
| 13 | Solar-Driven Producing of Value-Added Chemicals with Organic Semiconductor-Bacteria Biohybrid System显示文摘Photosynthetic biohybrid systems exhibit promising performance in biosynthesis;however,these systems can only produce a single metabolite and cannot further transform carbon sources into highly valuable chemical production.Herein,a photosynthetic biohybrid system integrating biological and chemical cascade synthesis was developed for solar-driven conversion of glucose to value-added chemicals.A new ternary cooperative biohybrid system,namely bacterial factory,was constructed by self-assembling of enzyme-modified light-harvesting donor-acceptor conjugated polymer nanoparticles(D-A CPNs)and genetically engineered Escherichia coli(E.coli).The D-A CPNs coating on E.coli could effectively generate electrons under light irradiation,which were transferred into E.coli to promote the 37%increment of threonine production by increasing the ratio of nicotinamide adenine dinucleotide phosphate(NADPH).Subsequently,the metabolized threonine was catalyzed by threonine deaminase covalently linking with D-A CPNs to obtain 2-oxobutyrate,which is an important precursor of drugs and chemicals.The 2-oxobutyrate yield under light irradiation is increased by 58%in comparison to that in dark.This work provides a new organic semiconductor-microorganism photosynthetic biohybrid system for biological and chemical cascade synthesis of highly valuable chemicals by taking advantage of renewable carbon sources and solar energy. | Wen Yu Haotian Bai Yue Zeng Hao Zhao Shengpeng Xia Yiming Huang Fengting Lv Shu Wang | 2022 | Research2022，，3： | 2 |
| 14 | Oligo(p-phenylenevinylene)-rhodium complex as intracellular catalyst for enhancing biosynthesis of polyhydroxybutyrate biomaterials显示文摘Microbial synthesis utilizes sustainable resources to produce valuable chemicals,as a potential alternative to petroleum-based chemical industry.Although metabolic engineering is an efficient method to enhance the biosynthesis efficacy of microorganisms,it requires complicated biological procedures.Herein,we report a facile intracellular catalysis system for augmenting the production of bio-based material in microorganism.Covalent linking of oligo(p-phenylenevinylene)(OPV)and cyclopentadienyl rhodium(Ⅲ)bipyridine offers intracellular metal catalyst(OPV-Rh).The OPV-Rh complex displayed certain resistance to toxic biomolecules,which guaranteed its catalytic activity in complicated biological systems.With uptake by Gramnegative bacterium Ralstonia eutropha H16(R.eutropha H16),the OPV-Rh complex promotes the transformation of intracellular NADP+to NADPH,which further enhances the biosynthesis of polyhydroxybutyrate(PHB)by this microorganism.This work demonstrates that synthetic metal catalyst can be employed for regulating microbial biosynthesis intracellularly. | Nan Dai Hao Zhao Wen Yu Fengting Lv Libing Liu Shu Wang | 2021 | Science China Chemistry2021，64，1： | 2 |
| 15 | Cationic conjugated polymers for detection and inactivation of pathogens显示文摘Conjugated polymers(CPs) are referred to a kind of fluorescent polymer materials with delocalized π-conjugated backbones.For the last decades, cationic CPs(CCPs) have been widely used in biosensor, imaging and biomedical fields due to their good photophysical properties and solubility in water medium resulting from side chain modification with ionized moieties. In this mini-review, we mainly introduced the applications of CCPs in detection and inactivation of pathogen with typical examples, and also briefly discussed the relevant mechanisms. We hold the expectation that this mini-review can offer researchers a general reference and inspire them to construct new systems with high performances of pathogen detection and antimicrobial activity. | Ping He Fengting Lv Libing Liu Shu Wang | 2017 | Science China Chemistry2017，60，12： | 1 |
| 16 | Removal of Cu(II) from aqueous solution by adsorption onto functionalized SBA-16 mesoporous silica 显示文摘 | Xiaoming Xue Fengting Li Liu Y | 2008 | Microporous and Mesoporous Materials2008，116，13： | 1 |
| 17 | Design of antibacterial peptide-like conjugated molecule with broad spectrum antimicrobial ability显示文摘Increasing multidrug-resistant(MDR) superbugs emerge worldwide causing a public health crisis. Consequently, it is urgent to find new antibiotics with efficient broad-spectrum antimicrobial activity. By virtue of versatility in molecular design, a new peptide-like cell membrane-broken molecule, oligo-(7,7′-bifluoren-benzo[c][1,2,5]thiadiazole)(OFBT) possessing a conjugated backbone and eight pendant guanidyl moieties was designed and synthesized. OFBT exhibits favorable broad-spectrum of antimicrobial activity to pathogens including Gram-negative and Gram-positive bacteria, and fungi with the minimum inhibitory concentration(MIC)below 3.0 μM. Moreover, OFBT exhibits high selectivity for pathogens over human cells to make it a promising broad spectrum antimicrobial agent. | Hui Chen Meng Li Zhang Liu Rong Hu Shengliang Li Yuan Guo Fengting Lv Libing Liu Yilin Wang Yuanping Yi Shu Wang | 2018 | Science China Chemistry2018，61，1： | 1 |
| 18 | Preparation of mesoporous poly (acrylic acid)/SiO 2 composite nanofiber membranes having adsorption capacity for indigo carmine dye显示文摘 | Ran Xu Min Jia Fengting Li Hongtao Wang Bingru Zhang Junlian Qiao | 2012 | Applied Physics A2012，，： | 1 |
| 19 | Immobilization of pyrene on quartz plate surface via a flexible long spacer and its sensing properties to dicarboxylic acids显示文摘A novel photo-induced luminescence film has been prepared by immobilizing pyrene on quartz plate surface via a flexible long spacer, 1,3-diaminopropane and 3-glycidoxypropyl trimethoxysilane. The film shows combined monomer and excimer emission of pyrene in both wet and dry states. Steady-state and time-resolved fluorescence emission meas-urements demonstrated that the excimer emission mainly came from direct excitation of ground state dimers, and/or monomers in aggregated state. Classical Birks?scheme plays little role in the formation of the excimers. The structures of the excimers formed during the excitation are complex. Both standard excimer of sandwich-like fully overlapped structure and distorted ex-cimer of partially overlapped structure exist in the excited state of the fluorophore. The emission of the film is sensitive to the presence of dicarboxylic acids, including ethanedioic acid, malonic acid, succinic acid, etc. The emission in the monomer and excimer region increases along with increasing the concentration of the dicarboxylic acids. The time needed for the emission to reach equilibrium depends on the nature of the acids. It has been shown that the longer the chain length of the acids, the more the time needed. This observation is explained by considering the conformational reorganization of the immobilized pyrene due to insertion of the dicarboxylic acids into the space between neighboring spacers. Experimental results from similar studies using formic acid and acetic acid are in support of this explanation. Furthermore, the response of the film to dicarboxylic acids is reversible. | GAO Lining FANG Yu Lü Fengting DING Liping | 2004 | Science China Chemistry2004，47，3： | 1 |
| 20 | Testing the formation of Ca-phosphonate precipitates and evaluating the anionic polymers as Ca-phosphonate precipitates and CaCO3 scale inhibitor in simulated cooling water显示文摘 | Zhang Bingru Zhang Li Li Fengting | 2010 | Corrosion Science2010，52，12： | 1 |
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