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| 1 | Isolation and Identification of Cancer Stem-Like Cells from Murine Melanoma Cell Lines显示文摘In current study,cancer stem-like cells in the murine melanoma B16F10 cells were investigated.CD phenotypes of the B16F10 cells were analyzed by flow cytometry,and the specific CD phenotype cells from the B16F10 cells were isolated by MACS.Then we used colony formation assay in soft agar media,the cell growth assay in serum-free culture media as well as the tumorigenicity investigation of the specific CD phenotype cells in C57BL/6 mice, respectively,to identify cancer stem-like cells in the B16F10 cells.The results showed that the B16F10 cells could form spherical clones in serum-free culture media,and the rate of clonegenesis of CD133 + ,CD44 + and CD44 + CD133 + cells was higher than that of CD133 - ,CD44 - and CD44 + CD133 - cells in soft agar media,respectively. The tumorigenic potential of CD133 + ,CD44 + ,CD44 + CD133 + cells and CD44 + CD133 + CD24 + cells was stronger than that of CD133 - ,CD44 - ,CD44 + CD133 - cells and CD44 + CD133 + CD24 - cells in mice,respectively.In conclusion,the CD44 + CD133 + CD24 + cells have some biological properties of cancer stem-like cells or are highly similar to the characteristics of cancer stem cells(CSC).These results provide an important method for identifying cancer stem-like cells in B16F10 cells and for further cancer target therapy. | Jun Dou Meng Pan Ping Wen Yating Li Quan Tang Lili Chu Fengshu Zhao Chuilian Jiang Weihua Hu Kai Hu Ning Gu | 2007 | Cellular & Molecular Immunology2007，4，6： | 25 |
| 2 | Identifying tumor stem-like cells in mouse melanoma cell lines by analyzing the characteristics of side population cells显示文摘 | Jun Dou Ping Wen Weihua Hu Yating Li Yun Wu Chunsheng Liu Fengshu Zhao Kai Hu Jing Wang Chuilian Jiang Xiangfeng He Ning Gu | 2009 | Cell Biology International2009，，8： | 1 |
| 3 | Study of immunotherapy of murine myeloma by an IL-21-based tumor vaccine in BALB/c mice显示文摘 | Dou Jun Chu Lili Zhao Fengshu | 2007 | Cancer Biol Ther2007，612，： | 1 |
| 4 | Study of immunotherapy of murine myeloma by an IL-21-based tumor vaccine in BALB/c mice显示文摘 | Dou Jun Chu Lili Zhao Fengshu | 2007 | Cancer Biol Ther2007，6，： | 1 |
| 5 | Bispectrum of stator phase current for fault detection of induction motor显示文摘 | Juggrapong Treetrong Jyoti K. Sinha Fengshu Gu Andrew Ball | 2009 | ISA Transactions2009，，3： | 1 |
| 6 | Perturbing tumor cell metabolism with a Ru(Ⅱ)photo-redox catalyst to reverse the multidrug resistance of lung cancer显示文摘The novel concept of enzyme photocatalysis has recently attracted much attention in developing anticancer therapy.However,the relationship between coenzyme depletion and cellular metabolomic changes has rarely been investigated.Herein,we report the rational design of a deep-red light-triggered bis-tridentate Ru(Ⅱ)photocatalyst(Ru3),which induces cell metabolism disorder to combat multidrug resistance.Ru3 exhibits promising multiple triplet excited states,a long lifetime,and high photocatalytic activity toward the coenzyme.Consequently,Ru3 shows high phototherapeutic activity(photo index=191–833)against diverse resistant(cisplatin,5-fluorouracil,or paclitaxel)lung cancer cells by inhibiting cellular peptide,lipid,and glycerophospholipid metabolism.We believe that cell metabolism inhibition by photo-redox catalysts is an effective form of therapeutics for drug-resistant cancer cells. | Siqi Wei Hui Liang Anyi Dao Yuzhen Xie Fengshu Cao Qingyan Ren Ashish Kumar Yadav Rajesh Kushwaha Arif Ali Mandal Samya Banerjee Pingyu Zhang Shaomin Ji Huaiyi Huang | 2023 | Science China Chemistry2023，66，5： | 1 |
| 7 | Bispectrum of stator phase current for fault detection of induction motor显示文摘 | Juggrapong Treetrong Jyoti K. Sinha Fengshu Gu Andrew Ball | 2009 | ISA Transactions2009，，3： | 1 |
| 8 | 显示文摘 | XUQuan-sheng FENGShu YEDa-tian(许全盛 冯曙 叶大田) | | 光学·精密工程0，，： | 1 |
| 9 | Robust support vector regression networks for function approximation with outliers显示文摘 | Chen Chiachuang Shun Fengshu | 2002 | IEEE Trans on Neural Networks2002，16，6： | 1 |
| 10 | Zhejiang woos overseas investment显示文摘Located along China’s southeast coast and at the southem tip of the Yangtze River Delta and looking to Shanghai,China’s number one metroplius,Zhejiang Province has a land area of 100,000 square kilometres and a sea area of 260。 | Jia Fengshu and Liu Junhua | 1998 | 中国经贸画报1998，，9： | 0 |
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