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| 1 | Thermal cracking of aviation kerosene for scramjet applications显示文摘Thermal cracking of China No.3 aviation kerosene was studied experimentally and analytically under supercritical conditions relevant to regenerative cooling system for Mach-6 scramjet applications. A two-stage heated tube system with cracked products collection/analysis was used and it can achieve a fuel temperature range of 700―1100 K,a pressure range of 3.5―4.5 MPa and a residence time of ap-proximately 0.5―1.3 s. Compositions of the cracked gaseous products and mass flow rate of the kerosene flow at varied temperatures and pressures were obtained experimentally. A one-step lumped model was developed with the cracked mixtures grouped into three categories:unreacted kerosene,gaseous products and residuals including liquid products and carbon deposits. Based on the model,fuel conversion on the mass basis,the reaction rate and the residence time were estimated as functions of temperature. Meanwhile,a sonic nozzle was used for the control of the mass flow rate of the cracked kerosene,and correlation of the mass flow rate gives a good agreement with the measurements. | ZHONG FengQuan FAN XueJun YU Gong LI JianGuo | 2009 | Science China(Technological Sciences)2009，52，9： | 18 |
| 2 | Numerical investigation on flow and convective heat transfer of aviation kerosene at supercritical conditions显示文摘In this paper,characteristics of flow and convective heat transfer of China RP-3 kerosene in straight circular pipe were numerically studied.Navier-Stokes equations were solved using RNG k-turbulence model with low Reynolds number correction.The thermophysical and transport properties of the China RP-3 kerosene were calculated with a 10-species surrogate and the extended corresponding state method(ECS) combined with Benedict-Webb-Rubin equation.The independence of grids was first studied and the numerical results were then compared with experimental data for validation.Under flow conditions given in the paper,the results show that deterioration of convective heat transfer occurs when the wall temperature is slightly higher than the pseudo-critical temperature of kerosene for cases with wall heat flux of 1.2 and 0.8 MW/m 2.The degree of the heat transfer deterioration is weakened as the heat flux decreases.The deterioration,however,does not happen when the heat flux on the pipe wall is reduced to 0.5 MW/m 2.Based on the analysis of the near-wall turbulent properties,it is found that the heat transfer deterioration and then the enhancement are attributed partly to the change in the turbulent kinetic energy in the vicinity of pipe wall.The conventional heat transfer relations such as Sieder-Tate and Gnielinski formulas can be used for the estimation of kerosene heat convection under subcritical conditions,but they are not capable of predicting the phenomenon of heat transfer deterioration.The modified Bae-Kim formula can describe the heat transfer deterioration.In addition,the frictional drag would increase dramatically when the fuel transforms to the supercritical state. | DANG GuoXin ZHONG FengQuan CHEN LiHong CHANG XinYu | 2013 | Science China(Technological Sciences)2013，56，2： | 12 |
| 3 | Pandemonium Breaks Out:Disruption of Salicylic Acid-Mediated Defense by Plant Pathogens显示文摘Salicylic acid (SA) or 2-hydroxybenoic acid is a phenolic plant hormone that plays an essential role in plant defense against biotrophic and semi-biotrophic pathogens. In Arabidopsis, SA is synthesized from chorismate in the chloroplast through the ICS1 (isochorismate synthase I) pathway during pathogen infectioru The transcription co-activator NPR1 (Non-Expresser of Pathogenesis-Related Gene 1), as the master regulator of SA signaling, interacts with transcription factors to induce the expression of anti-microbial PR (Pathogenesis-Related) genes. To establish successful in fections, plant bacterial, oomycete, fun gal, and viral pathogens have evolved at least three major strategies to disrupt SA-mediated defense? The first strategy is to reduce SA accumulation directly by converting SA into its inactive derivatives. The second strategy is to interrupt SA biosynthesis by targeting the ICS1 pathway. In the third major strategy, plant pathogens deploy different mechanisms to interfere with SA downstream signaling. The wide array of strategies deployed by plant pathogens highlights the crucial role of disruption of SA-mediated plant defense in plant pathogenesis. A deeper understanding of this topic will greatly expand our knowledge of how plant pathogens cause diseases and consequently pave the way for the development of more effective ways to corn trol these diseases. | Guang Qi Jian Chen Ming Chang Huan Chen Katherine Hall John Korin Fengquan Liu Daowen Wang Zheng Qing Fu | 2018 | Molecular Plant2018，11，12： | 5 |
| 4 | The Xanthomonas typeⅢeffector Xop AP prevents stomatal closure by interfering with vacuolar acidification显示文摘Plant stomata close rapidly in response to a rise in the plant hormone abscisic acid(ABA)or salicylic acid(SA)and after recognition of pathogenassociated molecular patterns(PAMPs).Stomatal closure is the result of vacuolar convolution,ion efflux,and changes in turgor pressure in guard cells.Phytopathogenic bacteria secrete typeⅢeffectors(T3Es)that interfere with plant defense mechanisms,causing severe plant disease symptoms.Here,we show that the virulence and infection of Xanthomonas oryzae pv.oryzicola(Xoc),which is the causal agent of rice bacterial leaf streak disease,drastically increased in transgenic rice(Oryza sativa L.)plants overexpressing the Xoc T3E gene Xop AP,which encodes a protein annotated as a lipase.We discovered that Xop AP binds to phosphatidylinositol 3,5-bisphosphate(Ptd Ins(3,5)P_(2)),a memb rane phospholipid that functions in p H control in lysosomes,membrane dynamics,and protein trafficking.Xop AP inhibited the acidification of vacuoles by competing with vacuolar H^(+)-pyrophosphatase(V-PPase)for binding to Ptd Ins(3,5)P_(2),leading to stomatal opening.Transgenic rice overexpressing Xop AP also showed inhibition of stomatal closure when challenged by Xoc infection and treatment with the PAMP flg22.Moreover,Xop AP suppressed flg22-induced gene expression,reactive oxygen species burst and callose deposition in host plants,demonstrating that Xop AP subverts PAMP-triggered immunity during Xoc infection.Taken together,these findings demonstrate that Xop AP overcomes stomatal immunity in plants by binding to lipids. | Longyu Liu Ying Li Zhengyin Xu Huan Chen Jingyi Zhang Brittany Manion Fengquan Liu Lifang Zou Zheng Qing Fu Gongyou Chen | 2022 | Journal of Integrative Plant Biology2022，64，10： | 3 |
| 5 | Modal identification of system driven by lévy random excitation based on continuous time AR model显示文摘Based on the continuous time AR model,this paper presents a new time-domain modal identification method of LTI system driven by the uniformly modulated lévy random excitation.The structural dynamic equation is first transformed into the observation equation and the state equation(namely,stochastic differential equation).Based on the property of the strong solution of the stochastic differential equation,the uniformly modulated function is identified piecewise.Then by virtue of the Girsanov theorem,we present the exact maximum likelihood estimators of parameters.Finally,the modal parameters are identified by eigen analysis.Numerical results show that the method not only has high precision and robustness but also has very high computing efficiency. | DU XiuLi 1,2 &WANG FengQuan 1 1 College of Civil Engineering,Southeast University,Nanjing 210096,China 2 School of Mathematical Sciences,Nanjing Normal University,Nanjing 210097,China | 2009 | Science China(Technological Sciences)2009，52，12： | 2 |
| 6 | Cosmological parameter fittings with the BICEP2 data显示文摘Combining the latest Planck,Wilkinson Microwave Anisotropy Probe(WMAP),and baryon acoustic oscillation(BAO)data,we exploit the recent cosmic microwave background(CMB)B-mode power spectra data released by the BICEP2 collaboration to constrain the cosmological parameters of the ACDM model,especially the primordial power spectra parameters of the scalar and the tensor modes,ns,s,r,nt.We obtain constraints on the parameters for a lensed ACDM model using the Markov Chain Monte Carlo(MCMC)technique,the marginalized 68%bounds are r=0.03070.09140.1043,ns=0.00610.00610.9617,s=0.01050.00970.0175,nt=0.45150.45790.5198.We find that a blue tilt for nt is favored slightly,but it is still well consistent with flat or even red tilt.Our r value is slightly smaller than the one obtained by the BICEP group,in that we permit nt as a free parameter without imposing the single-field slow roll inflation consistency relation.When we impose this relation,then r=0.04460.06090.2130.For most other parameters,the best fit values and measurement errors are not altered significantly by the introduction of the BICEP2 data. | WU FengQuan LI YiChao LU YouJun CHEN XueLei | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，8： | 2 |
| 7 | PBS3 Protects EDS1 from Proteasome-Mediated Degradation in Plant Immunity显示文摘Plant immunity is controlled by both positive regulators such as PBS3 and EDS1 and negative regulators such as NPR3 and NPR4.However,the relationships among these important immune regulators remain elusive.In this study,we found that PBS3 interacts with EDS1 in both the cytoplasm and the nucleus,and is required for EDS1 protein accumulation?NPR3 and NPR4,which function as salicylic acid receptors and adaptors of Cullin3-based E3 ligase,interact with and mediate the degradation of EDS1 via the 26S proteasome.We further discovered that PBS3 inhibits the polyubiquitination and subsequent degradation of EDS1 by reducing the association of EDS1 with the Cullin3 adaptors NPR3 and NPR4.Furthermore,we showed that PBS3 and EDS1 also contribute to PAMP-triggered immunity in addition to effector-triggered immunity.Collectively,our study reveals a novel mechanism by which plants fine-tune defense resporises by inhibiting the degradation of a positive player in plant immunity. | Ming Chang Jinping Zhao Huan Chen Guangyong Li Jian Chen Min Li Ian A.Palmer Junqi Song James R.Alfano Fengquan Liu Zheng Qing Fu | 2019 | Molecular Plant2019，12，5： | 2 |
| 8 | Study of turbulent heat transfer of aviation kerosene flows in a curved pipe at supercritical pressure显示文摘 | Xunfeng Li Fengquan Zhong Xuejun Fan Xiulan Huai Jun Cai | 2010 | Applied Thermal Engineering2010，，13： | 2 |
| 9 | Convective heat transfer characteristics of China RP-3 aviation kerosene at supercritical pressure显示文摘 | Xunfeng Li Xiulan Huai Jun Cai Fengquan Zhong Xuejun Fan Zhixiong Guo | 2011 | Applied Thermal Engineering2011，，14： | 2 |
| 10 | α-Lipoic Acid Exerts Its Antiviral Effect against Viral Hemorrhagic Septicemia Virus(VHSV) by Promoting Upregulation of Antiviral Genes and Suppressing VHSV-Induced Oxidative Stress显示文摘Viral hemorrhagic septicemia virus(VHSV), belonging to the genus Novirhabdovirus, Rhabdoviridae family, is a causative agent of high mortality in fish and has caused significant losses to the aquaculture industry. Currently, no effective vaccines, Food and Drug Administration-approved inhibitors, or other therapeutic intervention options are available against VHSV. α-Lipoic Acid(LA), a potent antioxidant, has been proposed to have antiviral effects against different viruses. In this study, LA(CC_(50)= 472.6 lmol/L) was repurposed to exhibit antiviral activity against VHSV. In fathead minnow cells,LA significantly increased the cell viability post-VHSV infection(EC_(50)= 42.7 lmol/L), and exerted a dose-dependent inhibitory effect on VHSV induced-plaque, cytopathic effects, and VHSV glycoprotein expression. The time-of-addition assay suggested that the antiviral activity of LA occurred at viral replication stage. Survival assay revealed that LA could significantly upregulated the survival rate of VHSV-infected largemouth bass in both co-injection(38.095% vs. 1.887%,P < 0.01) and post-injection manner(38.813% vs. 8.696%, P < 0.01) compared with the control group. Additional comparative transcriptome and q RT-PCR analysis revealed LA treatment upregulated the expression of several antiviral genes, such as IRF7, Viperin, and ISG15. Moreover, LA treatment reduced VHSV-induced reactive oxygen species production in addition to Nrf2 and SOD1 expression. Taken together, these data demonstrated that LA suppressed VHSV replication by inducing antiviral genes expression and reducing VHSV-induced oxidative stress. These results suggest a new direction in the development of potential antiviral candidate drugs against VHSV infection. | Wanwan Zhang Xiaoqi Chen Fangzhao Yu Fengquan Li Wangdong Li Meisheng Yi Kuntong Jia | 2021 | Virologica Sinica2021，36，6： | 2 |
| 11 | Heat Transfer of Aviation Kerosene at Supercritical Conditions显示文摘 | Fengquan Zhong Xuejun Fan Gong Yu | 2008 | AIAA2008，4615，： | 1 |
| 12 | Object request brokers for distributed measurement 显示文摘 | He Feng Wang Fengquan Li Wei Han Xiaolin Liu Jianhua | 2001 | IEEE Computer Applications in Power2001，14，1： | 1 |
| 13 | A method to determine the boundary conditions of the finite element model of a slender beam using measured modal parameters显示文摘 | WANG Fengquan CHEN Shiyu | 1996 | Journal of Vibration and Acoustics Transactions oftheASME1996，118，3： | 1 |
| 14 | Paclitaxelinduced apoptosis in osteosarcoma cell line U2-OS显示文摘 | GUO WEI ZENG CHUN DONG FENGQUAN | 2002 | Chin Med J2002，115，12： | 1 |
| 15 | 全国环境天然放射性水平调查中的数据处理规定显示文摘 | Hu Fengquan(China Institute for Radiation Protection Taiyuan 030006) | 1995 | 辐射防护1995，，06： | 1 |
| 16 | On the Cauchy problem for the evolution p-Laplacian equations with gradient term and source and measures as initial data显示文摘 | SHANG Haifeng LI Fengquan | 2010 | Nonlinear Anal2010，72，： | 1 |
| 17 | Hapten heterology for a specific and sensitive indirect enzyme-linked immunosorbent assay for organophosphorus insecticide fenthion显示文摘 | Qi Zhang Laibao Wang Ki Chang Ahn Qin Sun Baishi Hu Jie Wang Fengquan Liu | 2007 | Analytica Chimica Acta2007，，2： | 1 |
| 18 | Development of a sensitive ELISA for the analysis of the organophosphorous insecticide fenthion in fruit samples显示文摘 | Qi Zhang Qin Sun Baishi Hu Qing Shen Gang Yang Xiao Liang Xiao Sun Fengquan Liu | 2007 | Food Chemistry2007，，3： | 1 |
| 19 | Object Request Brokers for Distributed Measurement显示文摘 | Feng He Fengquan Wang Wei Li | 2001 | IEEE Computer Application in Power2001，，7： | 1 |
| 20 | The BZR1-EDS1 module regulates plant growth-defense coordination显示文摘Plants have developed sophisticated strategies to coordinate growth and immunity,but our understanding of the underlying mechanism remains limited.In this study,we identified a novel molecular module that reg-ulates plant growth and defense in both compatible and incompatible infections.This module consisted of BZR1,a key transcription factor in brassinosteroid(BR)signaling,and EDS1,an essential positive regulator of plant innate immunity.We found that EDS1 interacts with BZR1 and suppresses its transcriptional activ-ities.Consistently,upregulation of EDS1 function by a virulent Pseudomonas syringae strain or salicylic acid treatment inhibited BZR1-regulated expression of BR-responsive genes and BR-promoted growth.Furthermore,we showed that the cytoplasmic fraction of BZR1 positively regulates effector-triggered im-munity(ETI)controlled by the TIR-NB-LRR protein RPS4,which is attenuated by BZR1's nuclear transloca-tion.Mechanistically,cytoplasmic BZR1 facilitated AvrRps4-triggered dissociation of EDS1 and RPS4 by binding to EDS1,thus leading to efficient activation of RPS4-controlled ETI.Notably,transgenic expression of a mutant BZR1 that accumulates exclusively in the cytoplasm improved pathogen resistance without compromising plant growth.Collectively,these results shed new light on plant growth-defense coordina-tion and reveal a previously unknown function for the cytoplasmic fraction of BZR1.The BZR1-EDS1 mod-ule may be harnessed for the simultaneous improvement of crop productivity and pathogen resistance. | Guang Qi Huan Chen Dian Wang Hongyuan Zheng Xianfeng Tang Zhengzheng Guo Jiayu Cheng Jian Chen Yiping Wang Ming-yi Bai Fengquan Liu Daowen Wang Zheng Qing Fu | 2021 | Molecular Plant2021，14，12： | 1 |
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