|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | One-year clinical study of NeuroR egen scaffold implantation following scar resection in complete chronic spinal cord injury patients显示文摘The objective of this clinical study was to assess the safety and feasibility of the collagen scaffold, Neuro Regen scaffold, one year after scar tissue resection and implantation. Scar tissue is a physical and chemical barrier that prevents neural regeneration. However, identification of scar tissue is still a major challenge. In this study, the nerve electrophysiology method was used to distinguish scar tissue from normal neural tissue, and then different lengths of scars ranging from 0.5–4.5 cm were surgically resected in five complete chronic spinal cord injury(SCI) patients. The NeuroR egen scaffold along with autologous bone marrow mononuclear cells(BMMCs), which have been proven to promote neural regeneration and SCI recovery in animal models, were transplanted into the gap in the spinal cord following scar tissue resection. No obvious adverse effects related to scar resection or Neuro Regen scaffold transplantation were observed immediately after surgery or at the 12-month follow-up. In addition, patients showed partially autonomic nervous function improvement, and the recovery of somatosensory evoked potentials(SSEP) from the lower limbs was also detected. The results indicate that scar resection and Neuro Regen scaffold transplantation could be a promising clinical approach to treating SCI. | Zhifeng Xiao Fengwu Tang Jiaguang Tang Huilin Yang Yannan Zhao Bing Chen Sufang Han Nuo Wang Xing Li Shixiang Cheng Guang Han Changyu Zhao Xiaoxiong Yang Yumei Chen Qin Shi Shuxun Hou Sai Zhang Jianwu Dai | 2016 | Science China(Life Sciences)2016，59，7： | 18 |
| 2 | Peripheral blood MicroRNAs distinguish active ulcerative colitis and Crohn’s disease显示文摘 | FengWu Natalie JiaGuo HongyingTian MichaelMarohn SusanGearhart Theodore M.Bayless Steven R.Brant John H.Kwon | 2010 | Inflamm Bowel Dis2010，，1： | 6 |
| 3 | Buckling behavior of pipes in oil and gas wells | GAO Deli LIU Fengwu XU Bingye | 2002 | Progress in Natural Science:Materials International2002，12，2： | 4 |
| 4 | Community structure and spatial distribution of macrobenthos in the shelf area of the Bering Sea显示文摘Field investigations of marine macrobenthos were conducted at ten sites in the Bering Sea in July 2010. Altogether 90 species of macrobenthos belonging to 59 families and 78 genera were identified. Among them, 41 polychaetes, 16 mollusks, 23 crustaceans, three echinoderms, two cnidarians, one nemertean, one priapulid, two sipunculids, and one echiuran were identified. The average density and biomass of total macrobenthos were 984 ind./m2 and 1 207.1 g/m2 of wet weight, respectively. The predominant species in the study area were Scoloplos armiger, Eudorella pacifica, Ophiura sarsii, Heteromastus filiformis, Ennucula tenuis, and Harpiniopsis vadiculus by abundance, while the predominant species in this area was Echinarachnius parma by biomass. Hierarchical cluster analysis(Bray–Curtis similarity measure) revealed that two important benthic assemblages in the study area were Community A and Community B. Community A was stable and Community B was unstable, as shown by the Abundance/Biomass Comparisons(ABC) approach. The macrobenthic community structure in the shelf of the Bering Sea was characterized by its high abundance and biomass, high productivity but great heterogeneity. | WANG Jianjun HE Xuebao LIN Heshan LIN Junhui HUANG Yaqin ZHENG Chengxing ZHENG Fengwu LI Rongguan JIANG Jinxiang | 2014 | Acta Oceanologica Sinica2014，33，6： | 4 |
| 5 | Compaction Performance of Biomimetic Press Roller to Soil显示文摘 | Jin Tong Qingzhu Zhang Li Guo Yuan Chang Yingjie Guo Fengwu Zhu Donghui Chen Xin Liu | 2015 | Journal of Bionic Engineering2015，12，1： | 3 |
| 6 | Experiment study of a quartz tube falling particle receiver显示文摘这篇论文论述特殊设计的掉落的粒子接收装置的试验性的评估。一个石英试管在设计,粒子没被风与征服被使用。集中的太阳的放射被吸收并且由稳固的粒子变换成热精力流动里面石英试管。几个实验被进行在太阳的炉子系统上测试接收装置的动态热表演。在实验期间,最大的粒子温度上升是 212C,与 61.2% 的效率,它在小规模粒子接收装置与 0.2 m 的掉落的距离显示出好热表演。平均插头粒子温度被直接正常的发光(DNI ) 影响,象风那样的另外的因素加速。当更小的稳固的粒子更容易在螺旋石英试管困住时,稳固的粒子与更高的温度获得更大的粘性。,当稳固的粒子的温度增加,硅碳化物的热能力与粒子温度的上升变得更大,硅碳化物的温度上升减少。 | Tianjian WANG Fengwu BAI Shunzhou CHU Xiliang ZHANG Zhifeng WANG | 2017 | Frontiers in Energy2017，11，4： | 3 |
| 7 | Long-term clinical observation of patients with acute and chronic complete spinal cord injury after transplantation of Neuro Regen scaffold显示文摘Spinal cord injury(SCI)often results in an inhibitory environment at the injury site.In our previous studies,transplantation of a scaffold combined with stem cells was proven to induce neural regeneration in animal models of complete SCI.Based on these preclinical studies,collagen scaffolds loaded with the patients’own bone marrow mononuclear cells or human umbilical cord mesenchymal stem cells were transplanted into SCI patients.Fifteen patients with acute complete SCI and 51 patients with chronic complete SCI were enrolled and followed up for 2 to 5 years.No serious adverse events related to functional scaffold transplantation were observed.Among the patients with acute SCI,five patients achieved expansion of their sensory positions and six patients recovered sensation in the bowel or bladder.Additionally,four patients regained voluntary walking ability accompanied by reconnection of neural signal transduction.Among patients with chronic SCI,16 patients achieved expansion of their sensation level and 30 patients experienced enhanced reflexive defecation sensation or increased skin sweating below the injury site.Nearly half of the patients with chronic cervical SCI developed enhanced finger activity.These long-term follow-up results suggest that functional scaffold transplantation may represent a feasible treatment for patients with complete SCI. | Fengwu Tang Jiaguang Tang Yannan Zhao Jiaojiao Zhang Zhifeng Xiao Bing Chen Guang Han Na Yin Xianfeng Jiang Changyu Zhao Shixiang Cheng Ziqiang Wang Yumei Chen Qiaoling Chen Keran Song Zhiwei Zhang Junjie Niu Lingjun Wang Qin Shi Liang Chen Huilin Yang Shuxun Hou Sai Zhang Jianwu Dai | 2022 | Science China(Life Sciences)2022，65，5： | 3 |
| 8 | Biodiversity and community structural characteristics of macrobenthos in the Chukchi Sea显示文摘Field sampling of the macrobenthos from 23 stations in the Chukchi Sea was conducted during the 4th CHINARE(Chinese National Arctic Research Expeditions, July–August, 2010). We identified a total of 140 species of macrozoobenthos belonging to nine phyla, which were dominated by polychaetes(66), crustaceans(30), and mollusks(25), followed by echinoderms(9) and others(ten others, including four cnidarians, one oligochaete, one sipuncula, one priapulida, two bryozoans, and one urochordata). The dominant species were Aphelochaeta pacifica, Heteromastus filiformis, Nephtys ciliata, Nephtys caeca, Scoletoma fragilis, Golfingia margaritacea, Nuculana pernula, Macoma calcarea, Ennucula tenuis, Macoma inquinata, Musculus discors, Echinarachnius parma, and Ophiura sarsii, so there were more cold-eurythermal boreal immigrants than truly Arctic species(endemics). The average density and biomass(mean ± SD across all stations) of the total macrozoobenthos were(916 ± 907) ind/m2 and(902.9 ± 1 227.7) g/m2(wet weight), respectively. Relatively high density and biomass were observed in the samples from the northeastern and southern Chukchi Sea. The spatial variation of benthic communities in the study sea area was relatively large; this spatial heterogeneity has led to high diversity and a patchy distribution pattern in the community structure. Compared to the 1st CHINARE( July–August, 1999), this investigation revealed different degrees of decreases in the average taxa numbers and the average density, abundance, and biodiversity in the area over the recent decade, which might be associated with global warming, human activities, and sea ice variations. | WANG Jianjun LIN Heshan HE Xuebao LIN Junhui HUANG Yaqin LI Rongguan ZHENG Chengxing ZHENG Fengwu JIANG Jinxiang | 2014 | Acta Oceanologica Sinica2014，33，6： | 3 |
| 9 | Use of High Intensity Focused Ultrasound for Treating Malignant Tumors显示文摘OBJECTIVE To investigate the efficacy and side effects of high intensity focused ultrasound(HIFU) in the treatment of malignant solid tumors. METHODS Thirty patients who refused surgery and/or were refractory to chemotherapy were treated by HIFU alone, with the efficacy and side effects monitored as follows: observation of vital organ signs; functional assay of important organs; imaging examinations including: digital subtraction angiography (DSA), CT, MRI, single photon emission computed tomography (SPECT), large core needle biopsy, complications and metastasis. RESULTS After HIFU therapy, the vital signs remained stable and the functions of the heart, lung, kidney and liver were also normal. DSA images showed that small or larger arteries were not damaged. After a follow-up of 10-38 months(mean 23.1 months), 26 patients(87%) were alive. The volume of the tumor underwent complete regression in 10 patients. Shrinkage of the tumor volume ≥50% was observed in 13 patients. Eight of 13 patients were examined by large core needle biopsy, all showing necrosis and/or fibrosis though 3 patients(10%) had local recurrence. Two of these were retreated again by HIFU and the locally recurrent tumors were controlled. New metastases developed in 5 patients after H IFU. Two patients suffered from peripheral nerve injuriy and they have recovered during the follow-up. One patient developed skin injury. CONCLUSION High intensity focused ultrasound is effective and safe in the treatment of malignant solid tumors. | WenzhiChen ZhibiaoWang FengWu JinBai HuiZhu JianzhongZou KequanLi FanglinXie ZhilongWang | 2004 | Chinese Journal of Clinical Oncology2004，1，1： | 3 |
| 10 | Identification of microRNAs associated with ileal and colonic Crohn’s disease显示文摘 | FengWu SiminZhang ThemistoclesDassopoulos Mary L.Harris Theodore M.Bayless Stephen J.Meltzer Steven R.Brant John H.Kwon | 2010 | Inflamm Bowel Dis2010，，10： | 2 |
| 11 | Genome‐wide gene expression differences in Crohn’s disease and ulcerative colitis from endoscopic pinch biopsies: Insights into distinctive pathogenesis显示文摘 | FengWu ThemistoclesDassopoulos LeslieCope AnirbanMaitra Steven R.Brant Mary L.Harris Theodore M.Bayless GiovanniParmigiani ShuktiChakravarti | 2007 | Inflamm Bowel Dis2007，，7： | 2 |
| 12 | XPS Studies of Magnetic Multilayers显示文摘NiOx/N81Fe19 and Co/AlOx/Co magnetic multilayers were fabricated by reactive RF/DC magnetron sputtering on clean glass substrates and oxidized Si (100) substrates, respectively. The exchange biasing field (Hex) between NiOx, and Ni81Fe19 as a function of NiOx, oxidation states was studied by X-ray photoelectron spectroscopy (XPS). The oxidation states and the oxide thickness of Al layers in magnetic multilayer films consisting of Co/AlOx/Co were also analyzed. It is found that the Hex of NiOx/Ni81Fe19 films only depends on Ni2+ but not on Ni3+ or Ni. The bottom Co can be completely covered by depositing an Al layer thicker than 2.0 nm. The oxide layer was Al2O3, and its thickness was 1.15 nm. | Guanghua Yu, Hongchen Zhao, Jiao Teng, Chunlin Chai, Fengwu Zhu, Yang Xia, Shumin Chai Material Science and Engineering School, University of Science and Technology Beijing, Beijing 100083, China Microelectronics Center, Chinese Academy of Science, Beijin | 2001 | Journal of University of Science and Technology Beijing2001，8，3： | 2 |
| 13 | XPS Studies of Chemical States of NiO/NiFe Interface显示文摘Ta/NiO/NiFe/Ta multilayers were prepared by radio frequency reactive and dc magnetron sputtering. The exchange coupling field between NiO and NiFe reached 9.6×103 A/m. The compositions and chemical states at the interface region of NiO/NiFe were studied using the X-ray photoelectron spectroscopy (XPS) and peak decomposition technique. The results show that there are two thermodynamically favorable reactions at NiO/NiFe interface: NiO+Fe= Ni + FeO and 3NiO+2Fe =3 Ni+Fe203. The thickness of the chemical reaction area estimated by angle-resolved XPS was about 1-1.5 nm. These interface reaction products appear magnetic defects, and the exchange coupling field Hex and the coercivity Hc of NiO/NiFe are affected by these defects. | Guanghua Yu, Chunlin Chai, Fengwu Zhu, Jimei Xiao, Wuyan Lai 1)Materials Science and Engineering School, University of Science and Technology Beijing, Beijing 100083, China 2)Institute of Physics. Chinese Academy of Sciences. Beijing, 100080, China | 2001 | Journal of University of Science and Technology Beijing2001，8，4： | 2 |
| 14 | Structure and magnetic properties of vacuum annealed FePt/Ag nano-multilayers显示文摘FePt/Ag)n nano-multilayers were deposited on MgO(100) single crystal with laser ablation and then sub-jected to annealing. FePt L10 grains with (001) texture and a large perpendicular magnetic anisotropy constant Ku of the order of 106 J/m3 were formed. A thick Ag layer is found to be favorable for improving the (111) preferential orientation and decreasing the dispersion of the easy axis for magnetiza-tion. The measurement of time decay of magnetization gave rise to an activation volume as small as 6×10-25 m3, showing the promising perspective of being the recording medium for future high density perpendicular recording. | YANG Tao, YU Guanghua, HWANG Pol & ZHU Fengwu Department of Materials Physics, University of Science and Technology Beijing, Beijing 100083, China | 2003 | Chinese Science Bulletin2003，48，3： | 2 |
| 15 | Study of insulin counter regulatory hormones in critically ill children显示文摘 | Kuaong Fengwu Liu Zhongyi | 1997 | J Pediatr Childhealthy1997，，： | 1 |
| 16 | The synthesis of Li( Ni1/3Co1/3Mn1/3 )02 using eutec- tic mixed lithium salt LiNO3-LiOH 显示文摘 | Zhaorong Chang Zhongjun Chen FengWu | 2009 | Electrochimi- ca Acta2009，54，26： | 1 |
| 17 | Sensitivity analysis of the numerical study on the thermal performance of a packed-bed molten salt thermocline thermal storage system 显示文摘 | Xu Chao Wang Zhifeng He Yaling Li Xin Bai Fengwu | 2012 | Applied Energy2012，92，： | 1 |
| 18 | Effects of solid particle properties on the thermal performance of a packed-bed molten-salt thermocline thermal storage system 显示文摘 | Xu Chao Li Xin Wang Zhifeng He Yaling Bai Fengwu | 2013 | Applied ThermalEngineering2013，57，12： | 1 |
| 19 | Magnetic property and interface structure of Ta/NiO/NiFe/Ta显示文摘Ta/NiO/NiFe/Ta multilayers, utilizing Ta as buffer layer, were prepared by rf reactive and dc magnetron sputtering. The exchange coupling field between NiO and NiFe reached a maximum value of 9.6 ×103 A/m at a NiO film thickness of 50 nm. The composition and chemical states at interface region of Ta/NiO/Ta were studied by using the X-ray photoelectron spectroscopy (XPS) and peak decomposition technique. The results show that there is an 'intermixing layer' at the Ta/NiO (and NiO/Ta) interface due to a thermodynamically favorable reaction 2Ta + 5NiO = 5Ni + Ta2O5. This interface reaction has a great effect on exchange coupling. The thickness of Ni+NiO estimated by XPS depth-profiles is about 8-10 nm. | YU Guanghua CHAI Chunlin ZHU Fengwu XIAO Jimei | 2001 | Chinese Science Bulletin2001，46，5： | 1 |
| 20 | High - density cultivation of oleaginous yeast Rhodosporidium toruloides Y4 in fed - batch culture 显示文摘 | LI Yonghong ZHAO Zongbao BAI Fengwu | 2007 | Enzyme and Microbial Technology2007，41，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员