|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Nonalcoholic fatty liver disease in patients with inflammatory bowel disease: Beyond the natural history显示文摘BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a frequently reported condition in patients with inflammatory bowel disease(IBD).Both intestinal inflammation and metabolic factors are believed to contribute to the pathogenesis of IBDassociated NAFLD.AIM To evaluate the prevalence of steatosis and liver fibrosis(LF)in a cohort of IBD patients and the identification of metabolic-and IBD-related risk factors for NAFLD and LF.METHODS IBD patients were consecutively enrolled from December 2016 to January 2018.Demographic,anthropometric and biochemical data were collected so as eating habits.Abdominal ultrasound and transient elastography were performed to evaluate the presence of NAFLD and LF respectively.RESULTS A total of 178 consecutive patients were enrolled and included in the analysis(95 Ulcerative colitis,83 Crohn’s disease).NAFLD was detected by imaging in 72(40.4%)patients.Comparison between patients with and without NAFLD showed no significant differences in terms of IBD severity,disease duration,location/extension,use of IBD-related medications(i.e.,steroids,anti-TNFs,and immunomodulators)and surgery.NAFLD was significantly associated with the presence of metabolic syndrome[MetS;odds ratio(OR):4.13,P=0.001]and obesity defined by body mass index(OR:9.21,P=0.0002).IBD patients with NAFLD showed higher caloric intake and lipid consumption than those without NAFLD,regardless disease activity.At the multivariate analysis,male sex,advanced age and high lipid consumption were independent risk factors for the development of NAFLD.An increased liver stiffness was detected in 21 patients(16%)and the presence of MetS was the only relevant factor associated to LF(OR:3.40,P=0.01).CONCLUSION In this study,we demonstrate that risk factors for NAFLD and LF in the IBD population do not differ from those in the general population. | Salvatore Magrì Danilo Paduano Fabio Chicco Arianna Cingolani Cristiana Farris Giovanna Delogu Francesca Tumbarello Mariantonia Lai Alessandro Melis Laura Casula Massimo C Fantini Paolo Usai | 2019 | World Journal of Gastroenterology2019，25，37： | 8 |
| 2 | Successful outcome after combined chemotherapeutic and surgical management in a case of esophageal cancer with breast and brain relapse显示文摘Esophageal cancer (EC) is a highly lethal disease. Approximately 50% of patients present with metastatic EC and most patients with localized EC will have local recurrence or develop metastases, despite potentially curative local therapy. The most common sites of distant recurrence are represented by lung, liver and bone while brain and breast metastases are rare. Usually patients with advanced disease are not treated aggressively and their median survival is six months. We report a woman patient who developed breast and brain metastases after curative surgery. We treated her with a highly aggressive chemotherapeutic and surgical combination resulting in a complete remission of the disease even after 11-year follow-up. We think that in super selected patients with more than one metastasis, when functional status is good and metastases are technically resectable, a surgical excision may be considered as a salvage option and chemotherapy should be delivered to allow a systemic control. | Davide Adriano Santeufemia Gianfranca Piredda Giovanni Maria Fadda Paolo Cossu Rocca Salvatore Costantino Giovanni Sanna Maria Giuseppa Sarobba Maria Antonietta Pinna Carlo Putzu Antonio Farris | 2006 | World Journal of Gastroenterology2006，12，34： | 4 |
| 3 | Randomised trial comparing biweekly oxaliplatin plus oral capecitabine versus oxaliplatin plus i.v. bolus fluorouracil/leucovorin in metastatic colorectal cancer patients: results of the Southern Italy Cooperative Oncology study 0401显示文摘 | Pasquale Comella Bruno Massidda Gianfranco Filippelli Antonio Farris Donato Natale Giuseppe Barberis Luigi Maiorino Sergio Palmeri Michele Cannone Giovanni Condemi | 2009 | Journal of Cancer Research and Clinical Oncology2009，，2： | 2 |
| 4 | Clinicopathologic and Molecular Profiles of Microsatellite Unstable Barrett Esophagus-associated Adenocarcinoma显示文摘 | Farris AB 3rd Demicco EG Le LP | 2011 | Am J Surg Pathol2011，35，5： | 1 |
| 5 | A change in the early growth rate of larvae in marine fishery显示文摘 | FARRIS D A | 1959 | Limnol Oceanogr1959，，4： | 1 |
| 6 | Dry-jet Wet Spinning of Aromatic Polyamic Acid Fiber Using Chemical Imidization显示文摘 | Park S K Farris R J | 2001 | Polymer2001，42，10： | 1 |
| 7 | Mechanisms of urokinase plasminogen activator ( uPA)-mediated atheroselerosis: role of the uPA receptor and S100A8/A9 proteins显示文摘 | Farris SD Hu JH Krishnan R | 2011 | J Biol Chem2011，286，22： | 1 |
| 8 | Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation,sec-ondary pathology,and premature death显示文摘 | Leissring MA Farris W Chang AY | 2003 | Neuron2003，40，6： | 1 |
| 9 | Mechanisms of urokinase plasminogen activator-mediated atherosclerosis:role of the uPA receptor and S100A8/A9 proteins显示文摘 | Farris SD Hu JH Krishnan R | | 0，，： | 1 |
| 10 | 查看详情显示文摘 | Kang D Mead J Choi Y Farris R | | 0，，3： | 1 |
| 11 | Optic nerve sheath deco?mpression: a surgical technique with minimal operative complications显示文摘 | Moreau A Lao KC Farris BK | 2014 | J Neuroophthalmol2014，，： | 1 |
| 12 | Feasibility of brief smoking cessation intervention in community pharmacies 显示文摘 | PURCELL J L FARRIS K B AQUILINO M L | 2006 | J Am Pharm Assoc2006，46，5： | 1 |
| 13 | Substernal goiter:personal experience显示文摘 | Calo PG Tattia A Farris S | 2005 | Ann ItalChir2005，76，4： | 1 |
| 14 | Mechanics of fretting fatigue crack formation 显示文摘 | Szolwinski M P Farris J N | 1996 | Wear1996，198，： | 1 |
| 15 | The evolution of structure and properties in t:oly (p-phenylene terephthalamide ) fibers 显示文摘 | Rao Y Waddon A J FarriS R J | 2001 | Polymer2001，42，： | 1 |
| 16 | Retail Power: Monster or Mouse? 显示文摘 | Farris P W and Ailawaeli K L | 1992 | Journal of Retailing1992，68，： | 1 |
| 17 | Testing significance of incongruence显示文摘 | Farris JS M Kllersj AG Kluge and C Bult | 1995 | Cladistics1995，10，： | 1 |
| 18 | The Evolution of Structure and Properties in Poly ( p-phenylene Terephthalamide) Fibers 显示文摘 | Rao Y Waddon A J Farris R J | 2001 | Polymer2001，，42： | 1 |
| 19 | Acute toxicity of six freshwater mussel species (glochidia) to six chemicals: implications for Daphnids and Utterbackia imbeciUis as surrogates for protection of freshwater mussels (unionidae) 显示文摘 | Milam C D J L Farris F J Dwyer | 2005 | Arch Environ Contam Toxicol2005，48，2： | 1 |
| 20 | Contemporary Native American Women Artists: Visual Expressions of Feminism, the Environment, and Identity显示文摘 | Phoebe Farris | 2005 | Feminist Studies2005，31，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员