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| 1 | Physiopathology of splanchnic vasodilation in portal hypertension显示文摘In liver cirrhosis, the circulatory hemodynamic alterations of portal hypertension signifi cantly contribute to many of the clinical manifestations of the disease. In the physiopathology of this vascular alteration, mesen- teric splanchnic vasodilation plays an essential role by initiating the hemodynamic process. Numerous studies performed in cirrhotic patients and animal models have shown that this splanchnic vasodilation is the result of an important increase in local and systemic vasodilators and the presence of a splanchnic vascular hyporesponsiveness to vasoconstrictors. Among the molecules and factors known to be potentially involved in this arterial vasodilation, nitric oxide seems to have a crucial role in the physiopathology of this vascular alteration. However, none of the wide variety of mediators can be described as solely responsible, since this phenomenon is multifactorial in origin. Moreover, angiogenesis and vascular remodeling processes alsoseem to play a role. Finally, the sympathetic nervous system is thought to be involved in the pathogenesis of the hyperdynamic circulation associated with portal hypertension, although the nature and extent of its role is not completely understood. In this review, we discuss the different mechanisms known to contribute to this complex phenomenon. | María Martell Mar Coll Nahia Ezkurdia Imma Raurell Joan Genescà | 2010 | World Journal of Hepatology2010，2，6： | 13 |
| 2 | 液相飞行时间质谱(LC/MSD TOF)和液相色谱/离子阱质谱(LC/MSD Trap)测定色拉蔬菜中的氯烟碱类杀虫剂显示文摘本工作考察了液相色谱/飞行时间质谱检测器(LC/MSDTOF)和液相/离子阱质谱检测器(LC/MSDTrap)联用技术分析一些氯烟碱类杀虫剂的可行性.杀虫剂包括:啶虫咪(acetamiprid),吡虫啉(imidacloprid)和噻虫啉(thiacloprid).色拉蔬菜有四种:番茄、辣椒、莴苣和黄瓜.本文介绍的内容包括三种氯烟碱类杀虫剂的LC/MSDTOF和LC/MSDTrap质谱,TOF获得的实验分子式和四种蔬菜基质中氯烟碱类杀虫剂的MS/MS碎片离子.同时也将详细介绍样品制备程序以及色拉蔬菜中杀虫剂的回收、最低检测限(MDL)的质谱质量、线性,使用TOF和Trap对纯溶剂和四种蔬菜提取物中杀虫剂的定量分析.给出了来自市场的实际色拉蔬菜样品中杀虫剂的分析结果. | Imma Ferrer EMichael Thurman Jerry Zweigenbaum | 2005 | 环境化学2005，24，3： | 8 |
| 3 | 液相色谱/离子阱质谱和飞行时间质谱分析橄榄油中的特丁津除草剂显示文摘本文摘要介绍了液相色谱/离子阱质谱和液相/飞行时间质谱对橄榄油中特丁津的定性定量分析.详细介绍了样品处理,包括液液萃取和以氨基硅胶为基质分散的固相萃取法.样品的净化采用Florisil硅土小柱,用乙腈洗脱溶质.液相色谱/离子阱质谱的MS/MS模式采集特征离子m/z174.而利用液相/飞行时间质谱进行精确质量数分析(\[M+H\]+,m/z230),同时得到碎片的精确质量数和特征同位素分布.对于飞行时间质谱测得的质量精度小于ppm.此方法具有高灵敏度、线性好及精度高的优点.液相/离子阱质谱和飞行时间质谱可以作为橄榄油中特丁津的常规方法. | Imma Ferrer Michael Thurman Jerry Zweigenbaum | 2005 | 环境化学2005，24，6： | 5 |
| 4 | LC/TOF MS分子特征数据库检索方法进行食品中600种农药的自动筛选显示文摘通过液相色谱/飞行时间质谱在正离子模式下全扫描精确质谱测定,建立了分子特征(MF)算法进行数据库检索的方法用于筛选食品提取物中600种农药及其降解产物。数据库检索将实际化合物检测和鉴定中得到的离子的精确质量数收集起来,并且将它们与数据库中化合物的单一同位素的准确质量数进行比较。筛选标准包括:±5 ppm精确质量窗口;±0.2分钟保留时间窗口;最小峰面积计数1000(信噪比约为10:1)。检出限和保留时间是由600种化合物中的100种来确定,其中34%的化合物的检出限小于0.01mg/kg,95%的化合物的检出限小于0.5 mg/kg。与需要几小时到几天的手工方法相比,分子特征算法的优势在于它可以在几分钟内灵敏快速地筛选几百种化合物。 | E.Michael Thurman Imma Ferrer Jerry A.Zweigenbaum | 2010 | 食品安全质量检测学报2010，1，3： | 2 |
| 5 | Comparing Penman-Monteith and Priestley-Taylor approaches as reference-evapotranspiration inputs for modeling maize water-use under Mediterranean conditions a显示文摘 | Utset Angel Farre Imma Martinez-Cob Antonio | 2004 | Agricultural Water Management2004，66，3： | 1 |
| 6 | Multipathway Polycyclic Aromatic Hydrocarbon and Pyrene Exposure Among Children Living in Campania (Italy)显示文摘 | Teresa Cirillo Paolo Montuori Pierangela Mainardi Imma Russo Maria Triassi Renata Amodio-Cocchieri | 2006 | Journal of Environmental Science and Health Part A2006，，10： | 1 |
| 7 | Origin and vertical dynamics of particulate organic matter in a salt-wedge estuary,the Ebro Delta,inferred from lipid molecular markers and compound-specific isotope carbon analysis显示文摘 | Anna Gómez-Gutiérrez Imma Tolosa | 2011 | Marine Chemistry2011，126，： | 1 |
| 8 | Evidence of 2,7/2,8-dibe- nzodichloro-p-dioxin as a photodegradation product of triclosan in water anti wastewater samples显示文摘 | MILAGROS M GOMEZ M J IMMA F | 2004 | Analytica Chimica Acta2004，524，1： | 1 |
| 9 | Efficient heuristic algo- rithms for the blocking flow shop scheduling problem with to- tal flow time minimization显示文摘 | IMMA Ribas RAMON Companys | 2015 | Computers & Industrial Engi- neering2015，87，9： | 1 |
| 10 | Selective trace enrichment of chlorotriazine pesticides from natural waters and sediment samples using terbuthylazine molecularly imprinted polymers显示文摘 | IMMA F FRANCESCA L ANTAL T | 2000 | Anal Chem2000，72，： | 1 |
| 11 | An iterated greedy al- gorithm for the flowshop scheduling problem with blocking显示文摘 | IMMA R RAMON C XAVIER T M | 2011 | Omega2011，39，3： | 1 |
| 12 | Distribution of pigments and fatty acid biomarkers in particulate matter from the frontal structure of the Alboran Sea显示文摘 | IMMA T ISABELLE V NATHALIE L | 2004 | Marine Chemistry2004，88，： | 1 |
| 13 | Potato minituber production using aeroponics: effect of plant density and harvesting intervals 显示文摘 | Imma F Angel M | 2006 | American Journal of Potato Research2006，83，1： | 1 |
| 14 | Multi-residue method for the analysis of 101 pesticides and their degradates in food and water samples by liquid chromatography/time-of-flight mass spectrometry显示文摘 | Imma Ferrer E. Michael Thurman | 2007 | Journal of Chromatography A2007，，1： | 1 |
| 15 | Evidence of 2,7/2,8 - dibenzodichloro - p - dioxin as a photodegradation product of triclosan in water and wastewater sampies 显示文摘 | Milagros M Gomez M J Imma F | 2004 | Analytica Chimica Acta2004，524，1： | 1 |
| 16 | Clinical phar-macogenomic testing of KRAS,BRAF and EGFR mutations by highresolution melting analysis and ultra-deep pyrosequencing显示文摘 | Emma Borras Ismael Jurado Imma Hernan | 2011 | BMC Cancer2011，11，406： | 1 |
| 17 | Comparing Penman-Monteith and Priestley-Taylor approaches as reference-evapotranspiration inputs for modeling maize water-use under Mediterranean conditions a显示文摘 | Utset Angel Farre Imma Martinez-Cob Antonio | 2004 | Agricultural Water Management2004，66，3： | 1 |
| 18 | An iterated greedy algorithm for the flowshop scheduling problem with blocking 显示文摘 | Imma R Xavier R C T M | 2011 | Omega2011，39，3： | 1 |
| 19 | Analysis of sucralose and other sweeteners in water and beverage samples by liquid chromatography / time-of-flight mass spectrometry 显示文摘 | Imma Ferrer E Michael Thurman | 2010 | Journal of Chromatography A2010，1217，： | 1 |
| 20 | An iterated greedy algorithm for the flowshop scheduling problem with blocking显示文摘 | IMMA R XAVIER R C T M | 2011 | Ome- ga2011，39，3： | 1 |
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