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3篇 您的检索式:作者名="FREY Sabine"
    题名 作者 年代 出处 被引量
1On brain activity mapping: Insights and lessons from Brain Decoding Project to map memory patterns in the hippocampus显示文摘The BRAIN project recently announced by the president Obama is the reflection of unrelenting human quest for cracking the brain code, the patterns of neuronal activity that define who we are and what we are. While the Brain Activity Mapping proposal has rightly emphasized on the need to develop new technologies for measuring every spike from every neuron, it might be helpful to consider both the theoretical and experimental aspects that would accelerate our search for the organizing principles of the brain code. Here we share several insights and lessons from the similar proposal, namely, Brain Decoding Project that we initiated since 2007. We provide a specific example in our initial mapping of real-time memory traces from one part of the memory circuit, namely, the CA1 region of the mouse hippocampus. We show how innovative behavioral tasks and appropriate mathematical analyses of large datasets can play equally, if not more, important roles in uncovering the specific-to-general feature-coding cell assembly mechanism by which episodic memory, semantic knowledge, and imagination are generated and organized. Our own experiences suggest that the bottleneck of the Brain Project is not only at merely developing additional new technologies, but also the lack of efficient avenues to disseminate cutting edge platforms and decoding expertise to neuroscience community. Therefore, we propose that in order to harness unique insights and extensive knowledge from various investigators working in diverse neuroscience subfields, ranging from perception and emotion to memory and social behaviors, the BRAIN project should create a set of International and National Brain Decoding Centers at which cutting-edge recording technologies and expertise on analyzing large datasets analyses can be made readily available to the entire community of neuroscientists who can apply and schedule to perform cutting-edge research.TSIEN Joe Z. LI Meng OSAN Remus CHEN GuiFen LIN LongNian WANG Phillip Lei FREY Sabine FREY Julietta ZHU DaJiang LIU TianMing ZHAO Fang KUANG Hui 2013Science China(Life Sciences)2013,56,9:1
2Diverse expression patterns of the EMT suppressor grainyhead‐like 2 ( GRHL 2) in normal and tumour tissues显示文摘Sabine Riethdorf Sabrina Frey Sonja Santjer Malgorzata Stoupiec Benjamin Otto Lutz Riethdorf Christina Koop Waldemar Wilczak Ronald Simon Guido Sauter Klaus Pantel Volker Assmann 2016Int. J. Cancer2016,,:1
3Olfactory training is helpful in postinfectious olfactory loss: A randomized, controlled, multicenter study显示文摘Michael Damm Louisa K. Pikart Heike Reimann Silke Burkert ?nder G?ktas Boris Haxel Sabine Frey Ioannis Charalampakis Achim Beule Berthold Renner Thomas Hummel Karl‐Bernd Hüttenbrink 2014The Laryngoscope2014,,4:1
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