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| 1 | 脑静脉血栓形成的诊断和处理 美国心脏协会/美国卒中协会对医疗专业人员的声明显示文摘背景本指南旨在对脑静脉窦血栓形成(cerebral venous sinus thrombosis,CVT)进行概述,并提供其诊断、处理和治疗的推荐意见,目标读者为涉及CVT患者诊断和处理的临床医生和其他医疗工作者。方法和结果作为不同专业领域的代表,专家小组成员由美国心脏协会(American Heart Association,AHA)卒中委员会科学声明监督委员会任命。专家小组回顾了相关文献,重点为1966年以来公开发表的报道,并使用AHA证据水平分级方案对证据进行评定并制定推荐意见。本指南经专家小组认可后,由AHA科学咨询和协调委员会进行同行评议并批准。结论本指南为CVT的诊断、处理和复发的预防提供了循证推荐,同时还提供了妊娠期妇女和儿童CVT评估和处理的推荐意见,对临床并发症(痫性发作、脑积水、颅内压增高和神经功能恶化)的处理进行了总结,并描述了CVT患者诊断和治疗的流程图。 | Gustavo Saposnik Femando Barinagarrementeria Robert D. Brown Cheryl D. Bushnell Brett Cucchiara Mary Cushman Gabrielle deVeber Jose M. Ferro Fong Y. Tsai 张沈阳(译) 韩丽娟(译) 叶丹(译) 徐运(译) | 2011 | 国际脑血管病杂志2011，19，10： | 197 |
| 2 | 铝、镁轻合金中的稀土显示文摘综述了稀土镁和稀土铝合金的晶体化学、热力学和相图数据,根据其应用前景特别注意了富镁、富铝稀土合金及添加稀土对合金性能的影响,报道了若干稀土镁、稀土铝及含两个不同稀土的镁、铝合金的研究结果。对富镁、富铝的二元和三元合金相的结晶化学及形成规律进行了总结和讨论,并对有确定结构的合金精细设计和可能的应用提出了建议。 | Ferro R, Saccone A, Borzone G( Division of General and Inorganic Chemistry and Metallurgy Department of Chemistry, University of Genova, Dodecaneso 31,I 16146 Genova, Italy ) | 1997 | 中国稀土学报1997，15，3： | 36 |
| 3 | Triglyceride levels and apolipoprotein E polymorphism in patients with acute pancreatitis显示文摘BACKGROUND:Hypertriglyceridemia is an unusual cause of acute pancreatitis and sometimes considered to be an epiphenomenon.This study aimed to investigate the clinical and analytical features and the APOE genotypes in patients with acute pancreatitis and severe hypertriglyceridemia.METHODS:We undertook a one-year,prospective study of patients with acute pancreatitis whose first laboratory analysis on admission to the emergency department included measurement of serum triglycerides.The APOE genotype was determined and the patients answered an established questionnaire within the first 24 hours concerning their alcohol consumption,the presence of co-morbidities and any medications being taken.The patients' progression,etiological diagnosis,hospital stay and clinical and radiological severity were all recorded.RESULTS:Hypertriglyceridemia was responsible for 7 of 133 cases of pancreatitis (5%);the remaining cases were of biliary (53%),idiopathic (26%),alcoholic (11%) or other (5%) origin.Compared with these remaining cases,the patients with hypertriglyceridemia were significantly younger,had more relapses,and more often had diabetes mellitus.They usually consumed alcohol or consumed it excessively on the days before admission.Also,the ε4 allele of the APOE gene was more common in this group (P<0.05).CONCLUSION:One of 20 episodes of acute pancreatitis is caused by hypertriglyceridemia and it is linked to genetic (ε4 allele) and comorbid factors such as diabetes and,especially,alcohol consumption. | Radka Ivanova Susana Puerta Alfonso Garrido Ignacio Cueto Ana Ferro María José Ariza Andrés Cobos Pedro González-Santos Pedro Valdivielso | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，1： | 26 |
| 4 | Chloroplast Proteomics and the Compartmentation of Plastidial Isoprenoid Biosynthetic Pathways显示文摘proteomic 地里的最近的进展允许高产量的实验在叶绿体样品上被进行。许多 proteomic 调查集中了于整个叶绿体或 sub-plastidial 部分。迄今为止,植物蛋白质数据库(PPDB,阳光等, 2009 ) 介绍在网上可得到的最彻底的叶绿体 proteome。然而,在不同 sub-plastidial 分隔空间被识别的许多蛋白质的精确本地化仍然保持假想。为西班牙耶劳岛之旧称等。(2009 ) 去了进关于他们在由使用作为光谱的数知道的一条半量的 proteomic 途径的叶绿体以内的精确本地化的 Arabidopsis thaliana 叶绿体蛋白质的知识进一步的步。他们的 proteomic 策略基于精确的团和时间标签(AMT ) 数据库途径,他们建立了 AT_CHLORO,有 sub-plastidial 本地化的一个全面叶绿体 proteome 数据库和信封蛋白质的 curated 信息。比较这二个广泛的数据库,我们这里集中于涉及叶绿体特定的 isoprenoids 的合成的大约 100 酶。众所周知的小径(即甲基赤藻糖醇磷酸盐 biosynthetic 小径的分隔,在叶绿体以内的 tetrapyrroles 和叶绿素生合成和故障) 验证光谱基于计数的策略。一样的策略然后被用来在叶绿体以内识别类胡萝卜素和 prenylquinones 的生合成的精确本地化(即在信封膜,基质,或 thylakoids ) 那仍然保持不清楚直到现在。 | Jacques Joyard Myriam Ferro Christophe Masselon Daphne Seigneurin-Berny Daniel Salvi Jerome Garin Norbert Rolland | 2009 | Molecular Plant2009，2，6： | 15 |
| 5 | 经腹机器人辅助腹腔镜肾部分切除术治疗T2期肾肿瘤的国际多中心临床研究显示文摘目的通过国际多中心研究探讨临床T2期肾肿瘤行经腹机器人辅助腹腔镜肾部分切除术的安全性及有效性。方法回顾性分析2012年1月至2017年12月国际19家泌尿中心378例临床T2期肾肿瘤行经腹机器人肾部分切除术和经腹机器人根治性肾切除术患者的临床资料。根据手术方式不同,分为部分切除组和根治组。部分切除组159例,男118例,女41例;年龄(59.3±13.2)岁,体重指数(28.7±5.4) kg/m^2,术前GFR (77.3±22.1)ml/min;肿瘤位于左侧72例,右侧87例;肿瘤直径(83±16)mm;R.E.N.A.L.评分(8.6±2.2)分。根治组219例,男156例,女63例;年龄(62.0±12.9)岁,体重指数(28.7±6.1) kg/m^2,术前GFR (71.4±20.3)ml/min;肿瘤位于左侧112例,右侧105例,双侧2例;肿瘤直径(92±25)mm;R.E.N.A.L.评分(9.7±1.5)分。两组患者性别、体重指数、肿瘤位置的差异均无统计学意义(P〉0.05)。部分切除组患者年龄、肿瘤直径、R.E.N.A.L.评分均低于根治组(P〈0.05),术前GFR优于根治组(P=0.012)。比较两组围手术期资料、肿瘤病理类型、随访时间、复发时间及术后GFR等。结果378例手术均顺利完成。部分切除组手术时间中位值150 min(65-353 min),短于根治组[180 min(85-361 min),P〈0.001],术中出血量中位值150 ml(40-3 000 ml),多于根治组[100 ml (10-1 100 ml),P〈0.001]。术中并发症发生率部分切除组为5.7%(9/159),根治组为3.2%(7/219),两组差异无统计学意义(P=0.240)。部分切除组术后并发症发生率高于根治组[19.5%(31/159)与10.5%(23/219),P=0.014],但≥3级并发症发生率的差异无统计学意义[4.4%(7/159)与2.3%(5/219),P=0.246]。部分切除组无复发生存率高于根治组[91.4%(117/128)与81.9%(167/204),P=0.013]。部分切除组术后GFR降低值16.9 ml/min(10.4-84.7 ml/min)明显少于根治组29.0 ml/min(14.0-54.0 ml/min),肾部分切除术更利于术后肾功能的保护(P〈0.001)。结论临床T2期肾肿瘤行机器人肾部分切除术可获得有效的肿瘤控制率,同时可以更好地保护肾功能,可作为临床T2期肾肿瘤有效的手术方式。 | 过菲 张超 王富博 王林辉 杨庆 叶华茂 吕晨 肖成武 汪洋 Giuseppe Simone Ithaar Derweesh Andrea Minervini Daniel Eun Francesco Porpiglia Sisto Perdona James Porter Matteo Ferro Alexandre Mottrie Robert Uzzo Luigi Schips Wesley White Ken Jacobsohn Prokar Dasgupta Riccardo Autorino Clayton Lau Chandru Sundaram Umberto Capitanio 孙颖浩 杨波 | 2018 | 中华泌尿外科杂志2018，39，6： | 8 |
| 6 | A systematic review and meta-analysis of clinical trials implementing aromatase inhibitors to treat male infertility显示文摘Aromatase activity has commonly been associated with male infertility characterized by testicular dysfunction with low serum testosterone and/or testosterone to estradiol ratio.In this subset of patients,and particularly in those with hypogonadism,elevated levels of circulating estradiol may establish a negative feedback on the hypothalamic–pituitary–testicular axis by suppressing follicle-stimulating hormone(FSH)and luteinizing hormone(LH)production and impaired spermatogenesis.Hormonal manipulation via different agents such as selective estrogen modulators or aromatase inhibitors to increase endogenous testosterone production and improve spermatogenesis in the setting of infertility is an off-label option for treatment.We carried out a systematic review and meta-analysis of the literature of the past 30 years in order to evaluate the benefits of the use of aromatase inhibitors in the medical management of infertile/hypoandrogenic males.Overall,eight original articles were included and critically evaluated.Either steroidal(Testolactone)or nonsteroidal(Anastrozole and Letrozole)aromatase inhibitors were found to statistically improve all the evaluated hormonal and seminal outcomes with a safe tolerability profile.While the evidence is promising,future prospective randomized placebo-controlled multicenter trials are necessary to better define the efficacy of these medications. | Francesco Del Giudice Gian Maria Busetto Ettore De Berardinis Isabella Sperduti Matteo Ferro Martina Maggi Martin S Gross Alessandro Sciarra Michael L Eisenberg | 2020 | Asian Journal of Andrology2020，22，4： | 5 |
| 7 | Carbonized nano/microparticles for enhanced mechanical properties and electromagnetic interference shielding of cementitious materials显示文摘在现在的工作,碳 nano/microparticles 由花生(PS ) 的控制热分解获得了,榛子(HS ) 壳被介绍。这些材料被拉曼光谱学和地 emissionscanning 电子显微镜学(FE-SEM ) 描绘。当增加了水泥浆糊时,直到 1 wt% ,这些材料导致了水泥矩阵的增加曲折力量并且坚韧。而且关于平凡水泥,当在水泥 composites 增加 PS 或 HS 的 0.5 wt% 与相比是高得多的时,防护效果的电磁的放射的全部的增加为 CNT 在文学报导了,在一样的内容使用。 | Rao Arsalan KHUSHNOOD Sajjad AHMAD Luciana RESTUCCIA Consuelo SPOTO Pravin JAGDALE Jean-Marc TULLIANI Giuseppe Andrea FERRO | 2016 | Frontiers of Structural and Civil Engineering2016，0，2： | 4 |
| 8 | Worldwide trends in gastric cancer mortality (1980–2011), with predictions to 2015, and incidence by subtype显示文摘 | Ana Ferro Bárbara Peleteiro Matteo Malvezzi Cristina Bosetti Paola Bertuccio Fabio Levi Eva Negri Carlo La Vecchia Nuno Lunet | 2014 | European Journal of Cancer2014，，： | 3 |
| 9 | Renal denervation as an option for the management of hypertension显示文摘Hypertension is a multifactorial condition which makes the development of treatment approaches difficult.The vast majority of patients are treated with lifestyle measures either alone or in combination with antihypertensive drugs,and this approach is largely successful in controlling blood pressure.However,for a subgroup of patients,control of blood pressure remains resistant to this approach and therefore the development of new strategies is imperative.The sympathetic nervous system has been known to be implicated in hypertension for many decades,and evidence from studies in the past has revealed the benefit of reducing sympathetic nerve activity in the control of blood pressure albeit with severe side effects.Recent technological advances have allowed for specific targeting of the renal sympathetic nerves by catheter ablation.The Symplicity HTN-1 and HTN-2 trials have provided strong evidence for renal denervation giving rise to considerable blood pressure reductions in treatment-resistant hypertensives and,due to the high incidence of hypertension worldwide,this carries the promise of further reducing the global burden of hypertension and its attendant complications.Here we review the evidence for renal denervation in the management of hypertension. | Georgina Radhini Santiapillai Albert Ferro | 2014 | The Journal of Biomedical Research2014，28，1： | 3 |
| 10 | Emerging role of the KRAS-PDK1 axis in pancreatic cancer显示文摘Pancreatic cancer is a highly aggressive tumour that is very resistant to treatments and it is rarely diagnosed early because of absence of specific symptoms. Therefore, the prognosis for this disease is very poor and it has the grim supremacy in terms of unfavourable survival rates. There have been great advances in survival rates for many types of cancers over the past few decades but hardly any change for pancreatic cancer. Mutations of the Ras oncogene are the most frequent oncogenic alterations in human cancers. The frequency of KRAS mutations in pancreatic cancer is around 90%. Given the well-established role of KRAS in cancer it is not surprising that it is one of the most attractive targets for cancer therapy. Nevertheless, during the last thirty years all attempts to target directly KRAS protein have failed. Therefore, it is crucial to identify downstream KRAS effectors in order to develop specific drugs able to counteract activation of this pathway. Among the different signalling pathways activated by oncogenic KRAS, the phosphoinositide 3-Kinase(PI3K) pathway is emerging as one of the most critical KRAS effector. In turn, PI3 K activates several parallel pathways making the identification of the precise effectors activated by KRAS/PI3 K more difficult. Recent data identify 3-phosphoinositide-dependent protein kinase 1 as a key tumour-initiating event downstream KRAS interaction with PI3 K in pancreatic cancer. | Riccardo Ferro Marco Falasca | 2014 | World Journal of Gastroenterology2014，20，31： | 3 |
| 11 | Hepatitis delta virus: From infection to new therapeutic strategies显示文摘The hepatitis delta virus(HDV)is a small RNA virus that encodes a single protein and which requires the hepatitis B virus(HBV)-encoded hepatitis B surface antigen(HBsAg)for its assembly and transmission.HBV/HDV co-infections exist worldwide and show a higher prevalence among selected groups of HBV-infected populations,specifically intravenous drug users,practitioners of high-risk sexual behaviours,and patients with cirrhosis and hepatocellular carcinoma.The chronic form of HDV-related hepatitis is usually severe and rapidly progressive.Patterns of the viral infection itself,including the status of co-infection or super-infection,virus genotypes(both for HBV and HDV),and persistence of the virus’replication,influence the outcome of the accompanying and manifested liver disease.Unfortunately,disease severity is burdened by the lack of an effective cure for either virus type.For decades,the main treatment option has been interferon,administered as mono-therapy or in combination with nucleos(t)ide analogues.While its efficacy has been reported for different doses,durations and courses,only a minority of patients achieve a sustained response,which is the foundation of eventual improvement in related liver fibrosis.The need for an efficient therapeutic alternative remains.Research efforts towards this end have led to new treatment options that target specific steps in the HDV life cycle;the most promising among these are myrcludex B,which inhibits virus entry into hepatocytes,lonafarnib,which inhibits farnesylation of the viral-encoded LHDAg large hepatitis D antigen,and REP-2139,which interferes with HBsAg release and assembly. | Grazia A Niro Arianna Ferro Francesca Cicerchia Isabella Brascugli Marilena Durazzo | 2021 | World Journal of Gastroenterology2021，27，24： | 2 |
| 12 | 欧洲卒中组织脑静脉血栓形成诊断和治疗指南显示文摘目前的脑静脉血栓形成(cerebral venous thrombosis,CVT)诊断和管理指南由2010年欧洲神经病学联盟和2011年美国心脏学会和美国卒中学会制定。上述指南依据传统方法,结合具有科学证据的综述和专家意见,然后用矩阵模型结合推荐意见分类和关于证据分级系统,对证据和推荐意见进行分类。 | Ferro JM Bousser MG Canh?o P 吴川杰 张博维 段建钢 闫峰 吉训明 | 2018 | 中国脑血管病杂志2018，15，2： | 2 |
| 13 | 原因不明的脑卒中患者心房纤维化增加:心脏磁共振成像研究显示文摘一些被归类为原因不明的缺血性脑卒中患者可能有左心房和左心耳结构或功能的改变,增加了他们的血栓栓塞风险。该研究使用心脏磁共振成像比较不同病因的缺血性脑卒中患者的左心房和左心耳结构及功能。研究人员前瞻性连续纳入缺血性脑卒中患者样本。 | 刘莉 叶鹏 Fonseca AC Alves P Inácio N Marto JP Viana-Baptista M Pinho-E-Melo T Ferro JM Almeida AG | 2018 | 中华高血压杂志2018，26，3： | 2 |
| 14 | Hypofractionated and Low Dose Radiotherapy Combined with Temozolomide in Naive Unresectable Glioblastoma:A Pilot Study显示文摘Background/Aim: To assess safety of hypo-fractionated radiotherapy( HyRT) followed by low dose radiation therapy( LD-FRT) plus Temozolomide( TMZ) in naive unresectable Glioblastoma. Methods: Patients( ECOG < 2,age > 18) undergone to biopsy or with gross residual tumor after surgery were enrolled. HyRT( 30 Gy in ten fraction) plus TMZ was administered. From the second adjuvant cycle of TMZ,patients received LD-FRT( 0. 40 Gy twice daily over 5 days,every 28 days) for two cycles. The primary endpoints were safety and toxicity. Moreover we analyzed response,overall survival( OS) and progression-free survival( PFS). Results: Twenty patients were enrolled. Median dose of LD-FRT was 12 Gy. All toxicities were reversible. Four out of 20 patients had Partial Response( PR)and 6 experienced a stable disease( SD). Median OS and PFS were 14 and 11 months,respectively.Conclusions: HyRT followed by LD-FRT plus TMZ is safe and shows good clinical outcomes. A new study is ongoing. | Silvia Chiesa Milena Ferro Stefano Luzi Barbara Diletto Francesco Beghella Bartoli Nicola Dinapoli Gian Carlo Mattiucci Vincenzo Frascino Francesco Miccichè Cesare Colosimo Carmelo Anile Alessandro Olivi Vincenzo Valentini Mario Balducci | 2017 | 肿瘤预防与治疗2017，30，1： | 2 |
| 15 | Controlling European corn borer (Lepidoptera: Pyralidae) on successionally planted sweet corn in western Massachusetts显示文摘 | FERRO D N FLETCHER-HOWELL G | 1985 | J Eco Entomology1985，78，： | 2 |
| 16 | Diagnosis and Management of Cerebral Venous Thrombosis: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association显示文摘 | Gustavo Saposnik Fernando Barinagarrementeria Robert D. Brown Cheryl D. Bushnell Brett Cucchiara Mary Cushman Gabrielle deVeber Jose M. Ferro Fong Y. Tsai | 2011 | Stroke2011，，4： | 2 |
| 17 | Probability distributions of arsenic in soil from brownfield sites in Beijing (China): statistical characterization of the background populations and implications for site assessment studies显示文摘概率的分析在北京(Chaoyang 和 Haidian 区域) 从 4 个 brownfield 地点在土壤砷集中数据上被执行,在环境评价研究包含了。可得到的数据集合被处理提供背景人口的统计描述并且在土壤把异常数据区分开来与砷集中的变化的自然范围。地点特定的背景分布并且存在为北京区域定义的宽规模的背景价值被比较,为在地点评价屏蔽层次(SSL ) 的金属污染土壤的定义讨论相关含意学习。统计分析当数据集合区别了地点特定的背景人口,从孤立点价值,包含 88% ~ 94% 样品数据与任何一个心土天赋丰富或可能的人为的版本联系了。包括大多数地点特定的金属背景可变性,上面的基线集中(UBC ) 限制(2 铺平的 +) 基于背景人口的统计描述被导出。在 Chaoyang 南方区域区域的地点在范围有 UBC 价值 10.412.6 mg ???? 唠 ?嘠 吗?? | Marina ACCORNERO Lin JIANG Eugenio NAPOLI Marco CREMONINI Giovanni FERRO Federica BELLORO Maosheng ZHONG | 2015 | Frontiers of Environmental Science & Engineering2015，9，3： | 2 |
| 18 | The PG500 series: novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapy显示文摘 | K. Dredge E. Hammond K. Davis C. P. Li L. Liu K. Johnstone P. Handley N. Wimmer T. J. Gonda A. Gautam V. Ferro I. Bytheway | 2010 | Investigational New Drugs2010，，3： | 2 |
| 19 | A Floating CMOS Bandgap Voltage Reference for Differential Applications显示文摘 | Ferro M Salerno F Castello R | 1989 | IEEE J Solid-Stare Circuits1989，24，3： | 1 |
| 20 | Nerve complications in closed fractures of the lower end of theradius显示文摘 | Bourrel P Ferro RM | 1982 | Ann Chir Main1982，1，2： | 1 |
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