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| 1 | Fabrication and characterization of glass–ceramics materials developed from steel slag waste显示文摘 | Feng He Yu Fang Junlin Xie Jun Xie | 2012 | Materials and Design2012，，： | 2 |
| 2 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 3 | Fabrication and characterization of glass-ceramics materials developed from steel slagwaste 显示文摘 | He Feng Fang Yu Xie Junlin Xie Jun | 2012 | Materials and Design2012，42，： | 1 |
| 4 | Radiological thera py with low enery He Nelaser显示文摘 | WEI XINGCHANG LIU KAIXIANG FENG JUNLIN | 1995 | Chinese Physical Therapy Journal1995，18，2： | 1 |
| 5 | Identification of MnOx species and Mn valence states in MnOxlTiO, catalysts for low temperature SCR显示文摘 | Fang De Xie Junlin Hu Hua Yang Hu He Feng Fu Zhengbing | 2015 | Chemical Engineering Journal2015，271，： | 1 |
| 6 | Fabrication and Characterization of Glass-ceramics Materials Developed from Steel Slag Waste显示文摘 | He Feng Fang Yu Xie Junlin | 2012 | Materials and Design2012，42，： | 1 |
| 7 | Physics-Informed AI Surrogates for Day-Ahead Wind Power Probabilistic Forecasting with Incomplete Data for Smart Grid in Smart Cities显示文摘Due to the high inherent uncertainty of renewable energy,probabilistic day-ahead wind power forecasting is crucial for modeling and controlling the uncertainty of renewable energy smart grids in smart cities.However,the accuracy and reliability of high-resolution day-ahead wind power forecasting are constrained by unreliable local weather prediction and incomplete power generation data.This article proposes a physics-informed artificial intelligence(AI)surrogates method to augment the incomplete dataset and quantify its uncertainty to improve wind power forecasting performance.The incomplete dataset,built with numerical weather prediction data,historical wind power generation,and weather factors data,is augmented based on generative adversarial networks.After augmentation,the enriched data is then fed into a multiple AI surrogates model constructed by two extreme learning machine networks to train the forecasting model for wind power.Therefore,the forecasting models’accuracy and generalization ability are improved by mining the implicit physics information from the incomplete dataset.An incomplete dataset gathered from a wind farm in North China,containing only 15 days of weather and wind power generation data withmissing points caused by occasional shutdowns,is utilized to verify the proposed method’s performance.Compared with other probabilistic forecastingmethods,the proposed method shows better accuracy and probabilistic performance on the same incomplete dataset,which highlights its potential for more flexible and sensitive maintenance of smart grids in smart cities. | Zeyu Wu Bo Sun Qiang Feng Zili Wang Junlin Pan | 2023 | Computer Modeling in Engineering & Sciences2023，，10： | 1 |
| 8 | Spatial patterns of Picea crassifolia driven by environmental heterogeneity and intraspecifi c interactions显示文摘Research on the spatial patterns of tree populations is critical for understanding the structure and dynamic processes of forests.However,little is known about how the underlying drivers shape these patterns and species interactions in forest systems.In this study,spatial point pattern analysis investigated the combined eff ects of intraspecifi c interactions and environmental heterogeneity on the spatial structure and internal maintenance mechanisms of Picea crassifolia in the Qilian Mountain National Nature Reserve,China.Data were obtained from a 10.2-ha dynamic monitoring plot(DMP)and sixteen 0.04-ha elevation gradient plots(EGPs).Under complete spatial randomness,both mature trees and saplings in the DMP demonstratedlarge-scale aggregation with negative correlations.In EGPs,saplings were clustered in small mesoscales,mature trees were randomly distributed,and the interactions of saplingstrees at all elevations were not correlated.By eliminating the interference of environmental heterogeneity through the inhomogeneous Poisson process,saplings in the DMP and EGPs were clustered in small scales and trees randomly distributed.Intraspecifi c associations were negatively correlated,in the DMP and at low elevations,and no correlations in high elevations of EGPs.In the vertical scale,saplings showed a small-scale aggregation pattern with increase in elevation,and the aggregation degree fi rst decreased and then increased.The interactions of saplings-trees and saplings–saplings showed inhibitions at small scales,with the degree of inhibition gradually decreasing.Spatial patterns and associations of adults–adults did not change signifi-cantly.The results revealed that intraspecifi c interactions and environmental heterogeneity regulated the spatial patterns of P.crassifolia at small and large scales,respectively.Environmental heterogeneity might be the most decisive factor aff ecting the spatial patterns of saplings,while trees were more aff ected by intraspecifi c interactions.Moreover,competition between trees in this area could be more common than facilitation for the growth and development of individuals. | Changxing Zhao Weijun Zhao Ming Jin Jiqiang Zhou Feng Ta Lei Wang Wenbo Mou Longju Lei Jinrong Liu Junlin Du Xinglin Zhang | 2023 | Journal of Forestry Research2023，34，4： | 1 |
| 9 | Preparation and Microstructure of Glass-ceramics and Ceramic Composite Materials显示文摘The technology and microstructure of glass-ceramics and ceramic composite materials were studied. A suitable ceramic body was chosen on the basis of the sintering temperature of CaO-Al2O3-SiO2 system glass-ceramics. According to the expansion coefficient of the ceramic body, that of CaO-Al2O3-SiO2 system glass-ceramics was adjusted. β-wollastonite was found present as the major crystalline phase in glass-ceramic. The CaO-Al2O3-SiO2 system glass-ceramic layer and ceramic body could be sintered together by adjusting the sintering period. The compositions of glass-ceramic layer and ceramic body diffuse mutually at 1 100 ℃, resulting in an interface between them. To achieve good sintered properties of glass-ceramics and the chosen ceramic body, at least a four-hour sintering time is used. | HE Feng XIE Junlin HAN Da | 2008 | Journal of Wuhan University of Technology(Materials Science)2008，23，4： | 1 |
| 10 | Fabrication and characterization of glass-ceramics materials developed from steel slag waste 显示文摘 | Feng He Yu Fang Junlin Xie | 2012 | Materials and Design2012，42，： | 1 |
| 11 | Multi-omics analysis reveals the molecular regulatory network underlying the prevention of Lactiplantibacillus plantarum against LPS-induced salpingitis in laying hens显示文摘Background Salpingitis is one of the common diseases in laying hen production, which greatly decreases the economic outcome of laying hen farming. Lactiplantibacillus plantarum was effective in preventing local or systemic inflammation, however rare studies were reported on its prevention against salpingitis. This study aimed to investigate the preventive molecular regulatory network of microencapsulated Lactiplantibacillus plantarum(MLP) against salpingitis through multi-omics analysis, including microbiome, transcriptome and metabolome analyses.Results The results revealed that supplementation of MLP in diet significantly alleviated the inflammation and atrophy of uterus caused by lipopolysaccharide(LPS) in hens(P < 0.05). The concentrations of plasma IL-2 and IL-10 in hens of MLP-LPS group were higher than those in hens of LPS-stimulation group(CN-LPS group)(P < 0.05). The expression levels of TLR2, MYD88, NF-κB, COX2, and TNF-α were significantly decreased in the hens fed diet supplemented with MLP and suffered with LPS stimulation(MLP-LPS group) compared with those in the hens of CN-LPS group(P < 0.05). Differentially expressed genes(DEGs) induced by MLP were involved in inflammation, reproduction, and calcium ion transport. At the genus level, the MLP supplementation significantly increased the abundance of Phascolarctobacterium, whereas decreased the abundance of Candidatus_Saccharimonas in LPS challenged hens(P < 0.05). The metabolites altered by dietary supplementation with MLP were mainly involved in galactose, uronic acid, histidine, pyruvate and primary bile acid metabolism. Dietary supplementation with MLP inversely regulates LPSinduced differential metabolites such as Lyso PA(24:0/0:0)(P < 0.05).Conclusions In summary, dietary supplementation with microencapsulated Lactiplantibacillus plantarum prevented salpingitis by modulating the abundances of Candidatus_Saccharimonas, Phascolarctobacterium, Ruminococcus_torques_group and Eubacterium_hallii_group while downregulating the levels of plasma metabolites, p-tolyl sulfate, o-cresol and N-acetylhistamine and upregulating S-lactoylglutathione, simultaneously increasing the expressions of CPNE4, CNTN3 and ACAN genes in the uterus, and ultimately inhibiting oviducal inflammation. | Dan Song Aike Li Bingxu Chen Jia Feng Tao Duan Junlin Cheng Lixian Chen Weiwei Wang Yuna Min | 2024 | Journal of Animal Science and Biotechnology2024，15，1： | 0 |
| 12 | Amplification and Bioinformatics Analysis of vscN Gene from Vibrio alginolyticus显示文摘[Objectives]The paper was to clone and analyze bioinformatics of vscN gene from Vibrio alginolyticus.[Methods]A pair of specific primers was designed based on the vscN gene sequence of V.alginolyticus HY9901.The full length of vscN gene was amplified by PCR and bioinformatics analysis was performed.[Results]The vscN gene was 1323 bp in total,encoding 440 amino acids,with the theoretical molecular weight of 47.86 kD and the theoretical pI value of 5.89.The online prediction showed that there was no signal peptide and no transmembrane region in VscN.The amino acid sequence had 10 N-myristoylation sites,8 phosphorylation sites(2 protein kinase C phosphorylation sites,6 casein kinase II phosphorylation sites),1 amidation site,11 microbody C-terminal target signal sites,1 ATP/GTP binding site motif A(P ring),and 1 ATPaseαandβsubunit specific site.Homology analysis showed that the VscN protein of V.alginolyticus had high homology with that of V.antiquarius,with a similarity of 95.14%.Phylogenetic tree analysis showed that the VscN of V.alginolyticus was clustered into the same subgroup as that of V.diabolicus and V.antiquarius.Functional domain analysis of VscN protein showed that it had Pfam and AAA domains,and involved in the regulation of bacterial virulence.The three-dimensional structure model of VscN simulated by SWISS-MODEL software was similar to the structure of flagellate-specific ATPase FliH-FliI complex.[Conclusions]The results lay a foundation for further study on the regulatory mechanism of VscN protein on bacterial virulence. | Linlin YIN Wen LI Haiyun FENG Weijie ZHANG Junlin WANG Huanying PANG Na WANG | 2023 | Asian Agricultural Research2023，15，5： | 0 |
| 13 | Molecular Cloning and Bioinformatics Analysis of crp Gene in Vibrio alginolyticus显示文摘[Objectives]The crp gene in Vibrio alginolyticus was studied.[Methods]The crp gene of V.alginolyticus HY9901 was cloned and analyzed by bioinformatics.[Results]The ORF of the crp gene is 633 bp long and the predicted amino acid sequence encompasses 210 amino acid residues.The physicochemical property analysis indicated that the chemical formula of CRP is C_(1051)H_(1704)N_(290)O_(308)S_(10) with a molecular weight of 23.6514 kDa,and its theoretical pI is 7.74.Besides,the protein is stable and hydrophilic.The protein had three protein kinase C phosphorylation site,three casein kinase II phosphorylation site,one N-terminal myristoylation site.The BLAST analysis on the sequence revealed high homology with CRPs in other Vibrio species,and particularly the sequence shares about a homology of 99.52%with the CRP in V.parahaemolyticus.The SWISS-MODEL software simulated the subunit tertiary structural model of the CRP,and the similarity with template 3hif.1.A was 95.71%.[Conclusions]This study provides a reference for the search for efficient protective antigens against vibrosis. | Zhiqing WEI Weijie ZHANG Linlin YIN Haiyun FENG Junlin WANG Fuyuan ZENG Xing XIAO Huanying PANG | 2022 | Agricultural Biotechnology2022，11，2： | 0 |
| 14 | The Correlation Between Heart Failure and Gut Microbiome Metabolites显示文摘Heart failure(HF)is a global public health problem,with morbidity and mortality increasing year by year.The gut microbiome actively affects the physiological and pathological activities of the human body in a variety of ways.More and more studies have suggested a strong correlation between HF and gut microbiome metabolites.Our review summarizes the specific alteration of these metabolites and their connection to the progression of HF,aiming at considering new approaches toward regulating the gut microbiome and using its metabolic pathways to treat HF,potentially decreasing the morbidity and mortality of HF as well as improving prognosis. | Lina Chen Senhao Li Lanmu Ai Jun Zhou Junlin Huang Feng Xu Xiangyuan Zeng Jia Han Fangxue Yin Yixin Zhu Yifang Xie | 2020 | Infectious Microbes & Diseases2020，2，4： | 0 |
| 15 | Denitrification performance and sulfur resistance mechanism of Sm-Mn catalyst for low temperature NH_(3)-SCR显示文摘MnO_(x)and Sm–Mn catalysts were prepared with the coprecipitation method,and they showed excellent activities and sulfur resistances for the selective catalytic reduction of NO_(x)by NH_(3)between 50 and 300℃in the presence of excess oxygen.0.10Sm–Mn catalyst indicated better catalytic activity and sulfur resistance.Additionally,the Sm doping led to multi-aspect impacts on the phases,morphology structures,gas adsorption,reactions process,and specific surface areas.Therefore,it significantly enhances the NO conversion,N_(2)selectivity,and sulfur resistance.Based on various experimental characterization results,the reaction mechanism of catalysts and the effect of SO_(2)on the reaction process about the catalysts were extensively explored.For 0.10Sm–Mn catalyst,manganese sulfate and sulfur ammonium cannot be generated broadly under the influence of SO_(2)and the amount of surface adsorbed oxygen.The Bronsted acid sites strengthen significantly due to the addition of SO_(2),enhancing the sulfur resistance of the 0.10Sm–Mn catalyst. | Junlin Xie Yanli Ye Qinglei Li Tianhong Kang Sensheng Hou Qiqi Jin Feng He De Fang | 2023 | Frontiers of Chemical Science and Engineering2023，17，5： | 0 |
| 16 | A novel bioartificial pancreas fabricated via islets microencapsulation in anti-adhesive core-shell microgels and macroencapsulation in a hydrogel scaffold prevascularized in vivo显示文摘Islets transplantation is a promising treatment for type 1 diabetes mellitus. However, severe host immune rejection and poor oxygen/nutrients supply due to the lack of surrounding capillary network often lead to transplantation failure. Herein, a novel bioartificial pancreas is constructed via islets microencapsulation in core-shell microgels and macroencapsulation in a hydrogel scaffold prevascularized in vivo. Specifically, a hydrogel scaffold containing methacrylated gelatin (GelMA), methacrylated heparin (HepMA) and vascular endothelial growth factor (VEGF) is fabricated, which can delivery VEGF in a sustained style and thus induce subcutaneous angiogenesis. In addition, islets-laden core-shell microgels using methacrylated hyaluronic acid (HAMA) as microgel core and poly(ethylene glycol) diacrylate (PEGDA)/carboxybetaine methacrylate (CBMA) as shell layer are prepared, which provide a favorable microenvironment for islets and simultaneously the inhibition of host immune rejection via anti-adhesion of proteins and immunocytes. As a result of the synergistic effect between anti-adhesive core-shell microgels and prevascularized hydrogel scaffold, the bioartificial pancreas can reverse the blood glucose levels of diabetic mice from hyperglycemia to normoglycemia for at least 90 days. We believe this bioartificial pancreas and relevant fabrication method provide a new strategy to treat type 1 diabetes, and also has broad potential applications in other cell therapies. | Haofei Li Yulian Shang Qi Feng Yang Liu Junlin Chen Hua Dong | 2023 | Bioactive Materials2023，，9： | 0 |
| 17 | Continuous-discontinuous element method for three-dimensional thermal cracking of rocks显示文摘Thermal cracking of rocks can significantly affect the durability of underground structures in engineering practices such as geothermal energy extraction,storage of nuclear waste and tunnelling in freezeethaw cycle induced areas.It is a scenario of strong coupled thermomechanical process involving discontinuity behaviours of rocks.In this context,a numerical model was proposed to investigate the thermal cracking of rocks,in a framework of the continuous-discontinuous element method(CDEM)for efficiently capturing the initiation and propagation of multiple cracks.A simplex integration strategy was adopted to account for the influences of temperature-dependent material properties.Several benchmark tests were considered and the obtained results were compared with analytical solutions and numerical results from the literature.The results show that the fracture degree of the cases when considering temperature-dependent material parameters had 10%differences approximately compared with the cases with constant parameters. | Wen Nie Junlin Wang Chun Feng Yiming Zhang | 2023 | Journal of Rock Mechanics and Geotechnical Engineering2023，15，11： | 0 |
| 18 | Amplification and Bioinformatics Analysis of h-ns Gene of Vibrio alginolyticus显示文摘[Objectives]To amplify the h-ns gene of Vibrio alginolyticus and analyze it by bioinformatics.[Methods]According to the h-ns gene sequence of V.alginolyticus HY9901,a pair of specific primers were designed and amplified by PCR.[Results]The h-ns gene was 408 bp in length and 135 amino acids were encoded.The predicted theoretical protein molecular weight was about 14.98 kD,and the isoelectric point was 4.99.Protein subcellular localization,SignalP 5.0,TMHMM Server 2.0 and SoftBerry-Psite predictions showed that H-NS was located outside the cell membrane,and the protein was unstable and hydrophobic.There was no signal peptide cleavage site,no transmembrane region and no KEGG metabolic pathway.The amino acid sequence contained three phosphorylation sites,one N-terminal myristoylation site and three microsomal C-terminal target signal sites.Using MEGA 5.0,H-NS phylogenetic tree was constructed by ortho-connection method.The results showed that H-NS of V.alginolyticus was closer to H-NS of Vibrio diabolicus.Using SWISS-MODEL,the three-dimensional structure model of H-NS subunit was simulated,which was similar to the crystal structure of Salmonella typhimurium H-NS1-83.[Conclusions]This study lays a foundation for exploring the regulation mechanism of V.alginolyticus H-NS protein on bacterial virulence in the future. | Ying CHEN Shi WANG Liangchuan CHEN Haiyun FENG Junlin WANG Huanying PANG Na WANG | 2023 | Asian Agricultural Research2023，15，4： | 0 |
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