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| 1 | Air quality monitoring using mobile microscopy and machine learning显示文摘Rapid,accurate and high-throughput sizing and quantification of particulate matter(PM)in air is crucial for monitoring and improving air quality.In fact,particles in air with a diameter of≤2.5μm have been classified as carcinogenic by the World Health Organization.Here we present a field-portable cost-effective platform for high-throughput quantification of particulate matter using computational lens-free microscopy and machine-learning.This platform,termed c-Air,is also integrated with a smartphone application for device control and display of results.This mobile device rapidly screens 6.5 L of air in 30 s and generates microscopic images of the aerosols in air.It provides statistics of the particle size and density distribution with a sizing accuracy of~93%.We tested this mobile platform by measuring the air quality at different indoor and outdoor environments and measurement times,and compared our results to those of an Environmental Protection Agency–approved device based on beta-attenuation monitoring,which showed strong correlation to c-Air measurements.Furthermore,we used c-Air to map the air quality around Los Angeles International Airport(LAX)over 24 h to confirm that the impact of LAX on increased PM concentration was present even at 47 km away from the airport,especially along the direction of landing flights.With its machinelearning-based computational microscopy interface,c-Air can be adaptively tailored to detect specific particles in air,for example,various types of pollen and mold and provide a cost-effective mobile solution for highly accurate and distributed sensing of air quality. | Yi-Chen Wu Ashutosh Shiledar Yi-Cheng Li Jeffrey Wong Steve Feng Xuan Chen Christine Chen Kevin Jin Saba Janamian Zhe Yang Zachary Scott Ballard Zoltán Göröcs Alborz Feizi Aydogan Ozcan | 2017 | Light(Science & Applications)2017，6，1： | 5 |
| 2 | Discovery and validation of prognostic markers in gastric cancer by genome-wide expression profiling显示文摘AIM: To develop a prognostic gene set that can predict patient overall survival status based on the whole genome expression analysis. METHODS: Using Illumina HumanWG-6 BeadChip followed by semi-supervised analysis, we analyzed the expression of 47 296 transcripts in two batches of gastric cancer patients who underwent surgical resection. Thirty-nine samples in the first batch were used as the training set to discover candidate markers correlated to overall survival, and thirty-three samples in the second batch were used for validation. RESULTS: A panel of ten genes were identified as prognostic marker in the first batch samples and classified patients into a lowand a high-risk group with significantly different survival times (P = 0.000047). This prognostic marker was then verified in an independent validation sample batch (P = 0.0009). By comparing with the traditional Tumor-node-metastasis (TNM) staging system, this ten-gene prognostic marker showed consistent prognosis results. It was the only independent prognostic value by multivariate Cox regression analysis (P = 0.007). Interestingly, six of these ten genes are ribosomal proteins, suggesting a possible association between the deregulation of ribosome related gene expression and the poor prognosis. CONCLUSION: A ten-gene marker correlated with overall prognosis, including 6 ribosomal proteins, was identified and verified, which may complement the predictive value of TNM staging system. | Yue-Zheng Zhang Lian-Hai Zhang Yang Gao Chao-Hua Li Shu-Qinjia Ni Liu Feng Cheng De-Yun Niu William CS Cho Jia-Fu Ji Chang-Qing Zeng | 2011 | World Journal of Gastroenterology2011，17，13： | 5 |
| 3 | How to make rapid eyemovements 'rapid' : the role of growth factors for musclecontractile properties显示文摘 | Li T Feng CY von Bartheld CS | 2011 | Pflugers Arch2011，461，3： | 1 |
| 4 | Correlation of hypoxi- ainducible factor lalpha with angiogenesis in liver tumors after transcatheter arterial embolization in an animal mod- el 显示文摘 | Liang B Zheng CS Feng GS | 2010 | Cardiovase Intervent Radiol2010，，： | 1 |
| 5 | Correlation of hypoxiainducible factor 1alpha with angiogenesis in liver tumors after transcatheter arterial embolization in an animal mode显示文摘 | Liang B Zheng CS Feng GS | 2010 | Cardiovasc Intervent Radiol2010，，4： | 1 |
| 6 | Reversible water- marking: Current status and key issues显示文摘 | FENG JB LIN IC TSAI CS | 2006 | International Journal of Network Security2006，2，3： | 1 |
| 7 | Bone marrow findings in lupus patients with pancytopenia 显示文摘 | Feng CS Ng MH Szeto RS | 1991 | Pathology1991，23，： | 1 |
| 8 | Developmental changes in the delayed rectifier K ^+ channels in mouse heart 显示文摘 | Wang L Feng ZP Kondo CS | 1996 | Circ Res1996，79，1： | 1 |
| 9 | Biomechanical analysis of the disc adjacent to posterolateral fusion with laminectomy in lumbar spine显示文摘 | Chen CS Feng CK Cheng CK | | 0，，01： | 1 |
| 10 | Correlation of hypoxia-inducible factor 1alpha with angiogenesis in liver tumors after transcatheter arterial embolization in an animal model显示文摘 | Liang B Zheng CS Feng GS | | 0，，04： | 1 |
| 11 | A ntiangio-genic and A ntitumot Effects of Edostatin on Follicular Thyroid Carcinoma 显示文摘 | Ye CS Feng C Wang SM | 2002 | Endocrinology2002，143，9： | 1 |
| 12 | Antiangiogenie and antitu- mor effects of edostatin on follicular thyroid carcinoma 显示文摘 | Ye CS Feng C Wang SM | 2002 | '' Endocrinology2002，143，9： | 1 |
| 13 | Variant type B blood in an EI Salvador family: expression of a variant B gene enhanced by the presence of an A2 gene 显示文摘 | FENG CS COOK JL BEAUIE KM | 1984 | Transfusion1984，24，： | 1 |
| 14 | Biomechanical analysis of the disc adjacent to posterolateral fusion with laminectomy in lumbar spine显示文摘 | Chen CS Feng CK Cheng CK | 2005 | J Spinal Disord Tech2005，18，1： | 1 |
| 15 | Biomechanical analysis of the disc adjacent to posterolateral fusion with laminectomy in lumbar spine 显示文摘 | Chen CS Feng CK Cheng CK | 2005 | J Spinal Disord Tech2005，18，1： | 1 |
| 16 | Biomechanical analysis of the disc adjacent to posterolateral fusion with laminectomy in lumbar spine显示文摘 | Chen CS Feng CK Cheng CK | 2005 | J Spinal Disord Tech2005，18，1： | 1 |
| 17 | Developmental changes in the delayed rectifier K+ channels in mouse heart显示文摘 | Wang L Feng ZP Kondo CS | | 0，，： | 1 |
| 18 | Correlation of hypoxia-induc-ible factor lalpha with angiogenesis in liver tumors after tran-scatheter arterial embolization in an animal model显示文摘 | Liang B Zheng CS Feng GS | 2010 | CardiovascIntervent Radiol2010，33，4： | 1 |
| 19 | Correlation of hypoxia-in- ducible factoor-l alpha with angiogenesis in liver tumors after transcatheter arterial embolization in an animal model 显示文摘 | Liang B Zheng CS Feng GS | 2010 | Cardiovase Intervent Radiol2010，33，4： | 1 |
| 20 | Advances in fundamental and applied studies in China of fungal biocontrol agents for use against arthropod pests显示文摘 | Wang CS Feng MG | 2014 | Biological Control2014，68，1： | 1 |
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