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| 1 | Immunocytochemical identification and localization of APUD cells in the gut of seven stomachless teleost fishes显示文摘AIM To study the cell types,localization,distribution density and morphology of APUDcells in the intestinal mucosa of stomachlessteleost fishes.METHOD By using the peroxidase-antiperoxidase complex(PAP)immunocytochemical staining technique theidentification,localization and morphology ofimmunoreactive(IR)endocrine cells seattered inthe intestinal mucosa of grass carp(Cyenopharyngodon idellus),black carp(Mylopharyngodon piceus)and common carp(Cyprinus carpio)were investigated with 20kinds of antisera prepared against mammalianpeptide hormones of APUD cells,and likewise byusing avidin-biotin-peroxidase complex(ABC)method those of silver carp(Hypophthalmichthys molitrix),bighead(Aristichthys nobilis),silver crucian carp(Carassius gibelio)and bluntnose black bream(Megalobrama amblyocephala)were alsostudied with 5 different antisera.Thereplacement of the first antiserum by phosphatebuffered saline(PBS)was employed as a control.IR endocrine cells were counted with asquare-mesh ocular micrometer from 10 fieldsselected randomly in every section of each partof the intestine specimen.The average numberof IR endocrine cells per mm2 was counted toquantify their distribution density.RESULT Gastrin(GAS)-,Gastric inhibitorypeptide(GIP)-,glucagon(GLU)-,glucagon-likeimmunoreactants(GLI)-,bovine pancreaticpolypeptide(BPP)-,leucine-enkephalin(ENK)-and substance P(SP)-IR endocrine cells werefound in the gut of grass carp,black carp andcommon carp,and somatostatin(SOM)-IRendocrine cells were only seen in common carp.GAS-,GIP-and GLU-IR endocrine cells werefound in the intestinal mucosa of silver carp,bighead,silver crucian carp and bluntnose blackbream.Most of IR endocrine cells had the higherdistribution density in the foregut and midgut,and were longer in shape.They had a long apicalcytoplasmic process extended to the gut lumenand a basal process extended to adjacent cellsor basement membrane and touched with it.Sometimes,the basal cytoplasmic processformed an enlarged synapse-like structure in thecontiguous part with basement membrane.Thisphenomenon provided new morphologicalevidence for neuroendocrine and paracrinesecretory function of these enteroendocrinecells.CONCLUTION At least 8 kinds of IR endocrinecells were found in the gut of stomachlessteleost species for the first time in China.TheseIR endocrine cells scattering in the gut mucosabelong to the APUD system.Among them,thehormones secreted by SP-,ENK-,SOM-and GLU-IR endocrine cells belong to the peptides of dualdistribution in the brain and gut.This providednew evidence for the concept of brain-gutpeptide.According to the cell types,distribution density,morphologicalcharacteristics and variety in shape of APUDcells in the gut of stomachless teleost fishes,itis deemed that the digestive tract of fishes isalso an endocrine organ of great importance andcomplexity. | Pan QS Fang ZP Zhao YX | 2000 | World Journal of Gastroenterology2000，6，1： | 25 |
| 2 | Production of soybean isoflavone genistein in non-legume plants via genetically modified secondary metabolism pathway显示文摘 | Liu, RR Hu, YL Li, HL Lin, ZP | 2007 | 中国生物学文摘2007，21，10： | 15 |
| 3 | Localization of HCV RNA and capsid protein in human hepatocellular carcinoma显示文摘INTRODUCTIONThe relation of HCV to hepatocytic carcinoma(HCC) has been emphasized recently in low HBVinfection countries and regions.The distributionpatterns of HCV in liver tissues are not wellunderstood although studies on HCV infection inblood and hepatocytes have been conducted byPCR.In this study,42 liver cancers | Dai YM Shou ZP Ni CR Wang NJ Zhang SP | 2000 | World Journal of Gastroenterology2000，6，1： | 15 |
| 4 | Parkinson's disease in China: prevalence in Beijing, Xian, and Shanghai.显示文摘 | Zhang ZX Roman GC Hong Z Wu CB Qu QM Huang JB Zhou B Geng ZP Wu JX Wen HB Zhao H Zahner GE | 2006 | 中国生物学文摘2006，20，8： | 9 |
| 5 | The application of DGGE and AFLP-derived SCAR for discrimination between Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss)显示文摘 | Zhang JB Wang H J Cai ZP | 2007 | 中国生物学文摘2007，21，8： | 6 |
| 6 | Enthalpies of Formation of Binary Transition hcp Metal Based Alloys Calculated by Analytic Embedded Atom Method Model显示文摘A simple analytic modified embedded atom method (M EAM ) Inciuding a modified term for hcp metals has been developed from the MEAM applied to the fcc and bcc metals. The enthalpiesof formation of all binary alloy systems for eight transition hcp metals are calculated with theMEAM. The calculations are in agreement with the experimental data avallable and resultscalculated from the Miedema theory. One can conclude that our MEAM is also effective toapply to the hcp metals and their alloys. | Zhang, BW Ouyang, YF Liao, SZ Jin, ZP | 1999 | Journal of Materials Science & Technology1999，15，4： | 5 |
| 7 | Study of operator reliability in nuclear power plants显示文摘The study of the reliability of operator’s diagnosis and decision-making during abnormal events with HCR model has been introduced. A new approach has been proposed by the authors to deal with the classification of HIs. The modification of T0.5 by PSFs coefficients has been discussed. In addition, it is emphasized that T0. 5 and SD(σ) of response times can be used as a scale to predict and evaluate the reliability of crew/operator behavior. These processings provide improvement and refinement to HCR model and its practical application. The experiment for operator response time of Chinese NPP using a lull-scale simulator has proved the above-mentioned processings and presented the quantitative results of operator reliability in Chinese NPP. | Yang, MZ Gao, J Zhao, BQ Huang, XR Shen, ZP | 1997 | Chinese Science Bulletin1997，42，19： | 4 |
| 8 | DETERMINATION OF EFFECTIVE MODULI FOR FOAM PLASTICS BASED ON THREE PHASE SPHEROIDAL MODEL显示文摘The relations of bulk modulus,shear modulus,Young’s modulus and the Poisson’s ra-tio with porosity of foam plastics are determined by a three phase spheroidal model commonly used inComposite Mechanics.The results are compared with those using differential scheme.It is shownthat the material properties derived from the present model normally are larger than those obtained bydifferential scheme for foam plastics with identical porosity.The differences in shear moduli andYoung’s moduli obtained by the two methods are small,but they are larger for bulk moduli of incom-pressible matrix and Poisson’s ratios.The Young’s moduli of high density foam plastics derived by thepresent model agree better with experimental ones. | Lu, ZX Huang, ZP Wang, R | 1995 | Acta Mechanica Solida Sinica1995，8，4： | 3 |
| 9 | Simultaneous multi-tear exclusion:an optimal strategy for type B thoracic aortic dissection initially proved by a single center's 8 years experience显示文摘背景 Endovascular 接枝stent 广泛地被用来对待胸的大动脉的 dissection.However ,很少信息都不关于跟随八年用为斯坦福的治疗的同时的多眼泪排除的经验打 B 胸的大动脉的解剖导致到1月2006,29日类型 B 胸的大动脉的解剖病人的从1998年9月的没有不利 events.Methods 的成功的大动脉的改变的多重 tears.This 报告细节的同时的排除的结果是可得到的( 24 个人, 5 | YUAN Liang-xi BAO Jun-min ZHAO Zhi-qing FENG Xiang OU Le-feng FENG Rui LU Qing-sheng MEI Zhi-jun JING Zai-ping Department of Vascular Surgery,Changhai Hospital,Second Military Medical University Institute of Vascular Surgery of Chinese People’s Liberation Army Clinic Center of Vascular Diseases of Shanghai National Key Department of Vascular Surgery of China Shanghai 200433,China (Yuan LX,Bao JM,Zhao ZQ,Feng X,Ou LF,Feng R,Lu QS,Mei ZJ and Jing ZP) | 2007 | Chinese Medical Journal2007，，24： | 3 |
| 10 | 农药分散剂在江苏钟化研究所试生产成功显示文摘壬基酚聚氧乙烯醚甲醛缩合物磺酸钠盐(俗称“SOPA”)是由壬基酚与甲醛经缩合、与环氧乙烷聚合,再经磺化和盐转化而成,常应用于农药可湿性粉剂中,提高制剂的分散性能。目前江苏钟化研究所在实验室研究和扩试的基础上,成功地实现了SOPA工业化试生产,经物理性能和应用性能检测,各项指标均达到了设计要求。高性能的农药分散剂是水分散粒剂、悬浮剂、可湿性粉剂等农药制剂的关键组分,而水溶性高分子分散剂国内基本处于空白。 | ZP | 2007 | 农药2007，46，6： | 2 |
| 11 | Extrapolation non-reflecting boundary conditions显示文摘 | Liao ZP | 1996 | Wave Motion1996，24，： | 2 |
| 12 | Heterogeneity of c-myc expression in histologically similar infiltrating ductal carcinomas of the breast 显示文摘 | PAVELIC ZP PAVELIC K CARTER C P | 1992 | J Cancer Res Clin Oncol1992，118，1： | 1 |
| 13 | Magnetic resonance imaging and biological makers in pituitary adenomas with invasion of the cavernous sinus space显示文摘 | Chen ZP Liu YS | 2005 | J Neurooncol2005，74，： | 1 |
| 14 | Identification of a novel sulfonated oxysterol,5-cholesten-3beta,25-diol 3-sulfonate,in hepatocyte nuclei and mitochondria显示文摘 | Ren S Hylemon P Zhang ZP | 2006 | J Lipid Res2006，47，5： | 1 |
| 15 | Quantitative determination of hippuric and benzoic acids in mine by LC - MS/MS using surrogate standards 显示文摘 | Natalia P Penner Ragu R Joanna ZP | 2010 | J Pharmacet Biomed Anal2010，，52： | 1 |
| 16 | Allelopathic potential of watermelon tissues and root exudates显示文摘 | HAO ZP WANG Q CHRISTIE P | 2007 | Scientia Horticulturae2007，112，3： | 1 |
| 17 | Inhibition ofmRNA translation extends lifespan in Caenorhabditis elegans显示文摘 | Kally ZP Julia EP Arie NR | 2007 | Aging Cell2007，6，1： | 1 |
| 18 | Rrsults of 55 intracytoplasmic sperm injection cycles in the treatment of male immunological infertility显示文摘 | Nagy ZP Verheyen G Liu J | 1995 | Hum Reprod1995，10，： | 1 |
| 19 | Factors influencing the result of open reduction and internal fixation of tibial plateau fractur显示文摘 | Lachiewic ZP Funcik T | 1984 | Clin Orthop1984，，182： | 1 |
| 20 | Antibacterial and anti-adhensiveZeolite coatings on titanium alloy surface 显示文摘 | Wang JC Wang ZP Guo S | 2011 | Microporous andMesoporous Materials2011，146，： | 1 |
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