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| 1 | Cyclic vomiting syndrome in children: Experience with 181 cases from southern Iran显示文摘AIM: To evaluate the clinical presentation, response to prophylactic therapy and outcome of children with cyclic vomiting syndrome (CVS) in Shiraz, Iran.METHODS: During a period of 11 years (March 1994 to March 2005), 181 consecutive children with a final diagnosis of CVS were evaluated, treated and followed in our center. Patients were randomized to receive either amitriptyline or propranolol as prophylactic treatments. RESULTS: There were 88 boys and 93 girls with mean age of onset of symptoms of 4.9 ± 3.3 years (range, neonatal period to 14 years), the mean age at final diagnosis was 6.9 years (range, 1.5 to 14), and the mean duration between the onset of the first attack and the final diagnosis of CVS was 2 ± 1.81 years (range, 1/6 to 8). The mean duration of each attack was 4.26 days (range, from few hours to 10 d) and the mean interval between the attacks was 1.8 mo (range, 1 wk to 12 mo). The time of onset of the attacks was midnight to early morning in about 70% of cases. Amitriptyline was effective in 46 out of 81 (56%) patients (P < 0.001). Propranolol appeared to have a superior action and was effective in 74 out of 83 (92%) patients (P < 0.0001).CONCLUSION: There is a significant lag time between the onset of clinical symptoms and the final diagnosis of CVS in our area. In patients with typical clinical presentations of CVS, who are examined by an experienced physician, invasive workup is not necessary. Propranolol appears more effective than amitriptyline for prophylactic use in children with CVS. | Mahmood Haghighat Seyed Mohammad Rafie Seyed Mohsen Dehghani Gholam Hossein Fallahi Marzieh Nejabat | 2007 | World Journal of Gastroenterology2007，13，12： | 11 |
| 2 | Hepatitis C virus syndrome: A constellation of organ-and non-organ specific autoimmune disorders, B-cell nonHodgkin's lymphoma, and cancer显示文摘The clinical course of chronic hepatitis C virus(HCV)infection is characterized by possible development of both liver and extrahepatic disorders. The tropism of HCV for the lymphoid tissue is responsible for several immune-mediated disorders; a poly-oligoclonal B-lymphocyte expansion, commonly observed in a high proportion of patients with HCV infection, are responsible for the production of different autoantibodies and immune-complexes, such as mixed cryoglobulins. These serological alterations may characterize a variety of autoimmune or neoplastic diseases. Cryoglobulinemic vasculitis due to small-vessel deposition of circulating mixed cryoglobulins is the prototype of HCV-driven immune-mediated and lymphoproliferative disorders; interestingly, in some cases the disease may evolve to frank malignant lymphoma. In addition, HCV shows an oncogenic potential as suggested by several clinicoepidemiological and laboratory studies; in addition to hepatocellular carcinoma that represents the most frequent HCV-related malignancy, a causative role of HCV has been largely demonstrated in a significant percentage of patients with isolated B-cells nonHodgkin's lymphomas. The same virus may be also involved in the pathogenesis of papillary thyroid cancer, a rare neoplastic condition that may complicate HCVrelated thyroid involvement. Patients with HCV infection are frequently asymptomatic or may develop only hepatic alteration, while a limited but clinically relevant number can develop one or more autoimmune and/or neoplastic disorders. Given the large variability of their prevalence among patients' populations from different countries, it is possible to hypothesize a potential role of other co-factors, i.e., genetic and/or environmental, in the pathogenesis of HCV-related extra-hepatic diseases. | Clodoveo Ferri Marco Sebastiani Dilia Giuggioli Michele Colaci Poupak Fallahi Alessia Piluso Alessandro Antonelli Anna Linda Zignego | 2015 | World Journal of Hepatology2015，7，3： | 11 |
| 3 | Hepatitis C virus infection and type 1 and type 2 diabetes mellitus显示文摘Hepatitis C virus(HCV) infection and diabetes mellitus are two major public health problems that cause devastating health and financial burdens worldwide. Diabetes can be classified into two major types: type 1 diabetes mellitus(T1DM) and T2 DM. T2 DM is a common endocrine disorder that encompasses multifactorial mechanisms, and T1 DM is an immunologically mediated disease. Many epidemiological studies have shown an association between T2 DM and chronic hepatitis C(CHC) infection. The processes through which CHC is associated with T2 DM seem to involve direct viral effects, insulin resistance, proinflammatory cytokines, chemokines, and other immunemediated mechanisms. Few data have been reported on the association of CHC and T1 DM and reports on the potential association between T1 DM and acute HCV infection are even rarer. A small number of studies indicate that interferon-α therapy can stimulate pancreatic autoim-munity and in certain cases lead to the development of T1 DM. Diabetes and CHC have important interactions. Diabetic CHC patients have an increased risk of developing cirrhosis and hepatocellular carcinoma compared with nondiabetic CHC subjects. However, clinical trials on HCV-positive patients have reported improvements in glucose metabolism after antiviral treatment. Further studies are needed to improve prevention policies and to foster adequate and cost-effec-tive programmes for the surveillance and treatment of diabetic CHC patients. | Alessandro Antonelli Silvia Martina Ferrari Dilia Giuggioli Andrea Di Domenicantonio Ilaria Ruffilli Alda Corrado Silvia Fabiani Santino Marchi Clodoveo Ferri Ele Ferrannini Poupak Fallahi | 2014 | World Journal of Diabetes2014，5，5： | 7 |
| 4 | Challenging loop-mediated isothermal amplification(LAMP) technique for molecular detection of Toxoplasma gondii显示文摘Objective:To compare analytical sensitivity and specificity of a newly described DNA amplification technique.LAMP and nested PCR assay targeting the RE and Bl genes for the detection of Toxoplasma gondii(T.gondii) DNA.Methods:The analytical sensitivity of LAMP and ncstcd-PCR was obtained against 10-fold serial dilutions of T.gondii DNA ranging from 1 ng to 0.01 fg.DNA samples of other parasites and human chromosomal DNA were used to determine the specificity of molecular assays.Results:After testing LAMP and nesled-PCR in duplicate,the detection limit of RE-LAMP.B1-LAMP,RE-nested PCR and B1-nested PCR assays was one fg.100 fg,1 pg and 10 pg of T.gondii DNA respectively.All the LAMP assays and nested PCRs were 100% specific.The RE-LAMP assay revealed the most sensitivity for the detection of T.gondii DNA.Conclusions:The obtained results demonstrate that the LAMP technique has a greater sensitivity for detection of T.gondii.Furthermore,these findings indicate that primers based on the RE are more suitable than those based on the B1 gene.However,the B1-LAMP assay has potential as a diagnostic tool for detection of T.gondii. | Shirzad Fallahi Zahra Arab Mazar Mehrdad Ghasemian Ali Haghighi | 2015 | Asian Pacific Journal of Tropical Medicine2015，8，5： | 6 |
| 5 | 自体血清滴眼液对屈光性角膜切削术后角膜上皮愈合的影响(英文)显示文摘目的:研究自体血清滴眼液对屈光性角膜切削术(PRK)后角膜上皮愈合的影响。方法:本研究共纳入20例40眼近视及近视散光患者,其中男性9例,女性11例。每例患者随机选取一眼作为研究组应用20%含自体血清的人工泪液,另一眼为对照组应用常规人工泪液。PRK术中,40眼均于角膜表面居中放置直径8 mm的酒精储槽, 20%的酒精作用20s。术后每天观察直到角膜上皮愈合后,分别于1mo,6mo,12mo进行随访。上皮愈合时间为主要观察指标,并记录裸眼视力(UCVA),显然验光和混浊度。结果:两组间术前小瞳检影结果无明显差异。术后1d,2d,3d,研究组平均疼痛评分均显著低于对照组(P<0.05)。术后1d,3d,研究组的平均水平和垂直上皮缺损低于对照组(P<0.05)。研究组上皮完全愈合的平均时间比对照组短约0.7d(3.15±0.366d vs 3.85±0.587d,P=0.00)。结论:研究表明,应用自体血清滴眼液,通过加速角膜上皮愈合和减轻疼痛,从而缩短视力恢复时间,降低屈光性角膜切削术术后不适、混浊度和感染风险。 | Ali Mostafaei Behzad Fallahi Motlagh Nazli Taheri Siamak Nejatbakhsh | 2019 | 国际眼科杂志2019，19，4： | 3 |
| 6 | Effect of Various Field Shapers on Magnetic Pressure in Electromagnetic Inward Tube Forming显示文摘In this paper,the influence of various field shapers and their shapes on the distribution of the magnetic flux densities and applied forces on the work-piece in the electromagnetic inward tube forming are studied numerically using the FEA software MAXWELL.First the model was verified with experimental results and thereafter four kinds of field shapers(conical,cylindrical,concave and convex)were considered.Effects of their geometries,such as air gap between field shaper and tube work-piece,height of the step in single and multiple stepped field shaper on magnetic flux densities and magnetic pressures were studied.The results of this research can be applied to design field shaper,tube compression technology,and improve the efficiency of the coil.It is seen that magnetic force decreases if height of step in convex field shaper increases but effective forming region enlarges.Decreasing air gap has also a positive influence on magnetic field increase.Though the object of this research is limited to field shaper for inward tube forming,the results can also be applied to the field shaper for tube bulging. | Ehsan Garzan Hossein Ebrahimi Ali Reza Fallahi Arezoodar | 2012 | Journal of Iron and Steel Research(International)2012，19，S1： | 2 |
| 7 | Comparison of the RE and B1 gene for detection of Toxoplasma gondii infection in children with cancer显示文摘 | Sh. Fallahi B. Kazemi S.J. Seyyed tabaei M. Bandehpour Z. Lasjerdi N. Taghipour N. Zebardast B. Nikmanesh V. Fallah Omrani F. Ebrahimzadeh | 2014 | Parasitology International2014，，1： | 2 |
| 8 | Chaos secure communication scheme based on multiplication modulation显示文摘 | Fallahi K Leung H A | 2010 | Communications in Nonlinear Science and Numerical Simulation2010，15，2： | 1 |
| 9 | Incremental deformation and penetration analysis of deformable projectile into semi-infinite target显示文摘 | Khoda-rahmi H Fallahi A Liaghat G H | 2006 | International Journal of Solids and Structures2006，43，34： | 1 |
| 10 | A finite element formulation of a flexible slider-crank mechanism using local coordinate显示文摘 | Fallahi B Lai S Venkat C | 1995 | ASME J of Dynamic Systems Measurement & Control1995，117，3： | 1 |
| 11 | Changes in autonomic regulation and ventricular repolarization induced by subclinical hyperthyroidism显示文摘 | F. Galetta F. Franzoni P. Fallahi L. Tocchini F. Graci C. Gaddeo M. Rossi G. Cini A. Carpi G. Santoro A. Antonelli | 2009 | Biomedicine & Pharmacotherapy2009，，8： | 1 |
| 12 | Thyroid involvement in hepatitis C-associated mixed cryoglobulinemia显示文摘 | Fallahi P Ferrari SM Giuggioli D | 2014 | Hormones(Athens)2014，13，1： | 1 |
| 13 | Effect of particle film on fruit sunburn, maturity and quality of ' Fuji' and ' Honeycrisp' apples 显示文摘 | Schupp J R Fallahi E Chun I J | 2002 | Hort-Technology2002，12，1： | 1 |
| 14 | Causal relationship between energy consumption (EC) and GDP : A Markov - switching (MS) causality 显示文摘 | Fallahi F | 2011 | Energy2011，36，： | 1 |
| 15 | Clinical and subclinical autoimmune thyroid disorders in systemic sclerosis 显示文摘 | Antoelli A Ferri C Fallahi P | 2007 | Eur J Endocrinol2007，156，4： | 1 |
| 16 | Prevalence of thyroid dysfunctions in systemic lupus erythematosus 显示文摘 | Antonelli A Fallahi P Mosca M | 2010 | Metabolism2010，59，6： | 1 |
| 17 | Influence of rootstock on mineral uptake and scion growth of golden delicious and Royal gala apples显示文摘 | Amiri M E Fallahi E Safi-Songhorabad M | 2014 | Journal of Plant Nutrition2014，37，1： | 1 |
| 18 | Influence of nitrogen and bagging on fruit quality and mineral concentrations of BC-2 Fuji apple显示文摘 | Fallahi E Colt WM Baird CR | 2001 | Hort Technology2001，11，3： | 1 |
| 19 | A unified approach to form error evaluation显示文摘 | WEBER T MOTAVALLI S FALLAHI B | 2002 | Precision Engineering2002，26，3： | 1 |
| 20 | Cytokines and HCV-Related Disorders显示文摘 | Poupak Fallahi Clodoveo Ferri Silvia Martina Ferrari Alda Corrado Domenico Sansonno Alessandro Antonelli Jürg Schifferli | 2012 | Clinical and Developmental Immunology2012，，： | 1 |
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