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| 1 | Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer显示文摘Inflammatory bowel diseases are characterised by inflammation that compromises the integrity of the epithelial barrier. The intestinal epithelium is not only a static barrier but has evolved complex mechanisms to control and regulate bacterial interactions with the mucosal surface. Apical tight junction proteins are critical in the maintenance of epithelial barrier function and control of paracellular permeability. The characterisation of alterations in tight junction proteins as key players in epithelial barrier function in inflammatory bowel diseases is rapidly enhancing our understanding of critical mechanisms in disease pathogenesis as well as novel therapeutic opportunities. Here we give an overview of recent literature focusing on the role of tight junction proteins, in particular claudins, in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer. | Jonathan Landy Emma Ronde Nick English Sue K Clark Ailsa L Hart Stella C Knight Paul J Ciclitira Hafid Omar Al-Hassi | 2016 | World Journal of Gastroenterology2016，22，11： | 39 |
| 2 | 论思维和STEM教育显示文摘随着全球化的STEM教育领域的迅速发展,各国对跨学科研究以及开发更新、更深入的STEM教育的学术研究的呼声也越来越高.文章聚焦思维这个话题,首先从历史发展的视角,简要概括分析了有关思维的不同观点,包括哲学的、心理的和学科的,揭示了思维概念和研究的历史传承.但在新兴的STEM教育背景下,思维需要重新概念化.文章提出了思维是多元的观点,初步探讨了STEM融合教育的这种方式,能够为学生提供充分的机会来有效地发展多元思维模式,并对未来关于思维的研究提出了可能的新研究领域和方向. | 李业平 SCHOENFELD A H DISESSA A A GRAESSER A C BENSON L C ENGLISH L D DUSCHL R A | 2019 | 数学教育学报2019，0，3： | 10 |
| 3 | Selection of Peptides with Semiconductor Binding Specificity for Directed Nanocrystal Assembly 显示文摘 | Whaley S R English D S Hu E L | 2000 | Nature2000，405，6787： | 1 |
| 4 | Examining the contribution of glacial till water to storm runoff using two and three-component hy-drograph separations 显示文摘 | Hinton M J Schiff S L English M C | 1994 | Water Resource Research1994，30，： | 1 |
| 5 | Genital mycoplasmas stimulate tumor necrosis factor-alpha and inducible nitric oxide synthase production from a murine macrophage cell line显示文摘 | Crouse DT English BK Livingston L | 1998 | Pediatr Res1998，44，： | 1 |
| 6 | Enhancing and tuning pho- non transport at vibrationally mismatched solid-solid interfhces显示文摘 | English T S Duda J C Smoyer J L | 2012 | Physics Review B2012，85，03： | 1 |
| 7 | A geographic information system-based modeling system for evaluating the cost of delivered energy crop feedstock显示文摘 | Graham R L English B C Noon C E | 2000 | Biomass and Bioenergy2000，18，4： | 1 |
| 8 | Information quality and regulation: a management perspective 显示文摘 | ENGLISH L P | 2004 | Studies in communication sciences2004，4，： | 1 |
| 9 | Globule size of emulsions and toxicity 显示文摘 | English L L | 1928 | Nat Hist Surv Bull1928，17，： | 1 |
| 10 | Ethical concerns relating to journal writing显示文摘 | English L | 2001 | New D/rect/ons for Adult and Continuing Education2001，90，： | 1 |
| 11 | Young Children's Combinatoric Strategies 显示文摘 | English L D | 1991 | Educational Studies in Mathematics1991，，22： | 1 |
| 12 | Chemose-lective hydrogenation of unsaturated carbanyl-compounds over group-8 and group-9 titania-supported metal catalyst 显示文摘 | Raa C G English M Marinelli T B L W | 1993 | Stud Surf Sci Catal1993，78，： | 1 |
| 13 | Children's Strategies for Solving Two-and Three-dimensional Combinatorial Problems 显示文摘 | English L D | 1993 | Journal for Research in Mathematics Education1993，，24： | 1 |
| 14 | Driving privately financed projects in Australia: what makes them tick 显示文摘 | English L M Guthrie J | 2003 | Accounting Auditing & Accountability Journal2003，16，3： | 1 |
| 15 | Autopsy findings in an outbreak of severe systemic illness in hero in users follow- ing injection site inflammation: an effect o f clostridium novyi exotox in显示文摘 | FINN SP LEEN E ENGLISH L | 2003 | Arch Pathol Lab Med2003，127，11： | 1 |
| 16 | National Ignition Facility main laser light analysis and control显示文摘 | John L Miller R Edward English Jr John C Schweyen | 1998 | SPIE1998，3492，： | 1 |
| 17 | Laboratory-directed protein evolution 显示文摘 | Yuan L Kurek I English J | 2005 | Microbiol Mol Biol Rev2005，69，3： | 1 |
| 18 | Genetic variation of wild and hatchery populations of the Pacific oyster,Crassostrea gigas (Thunberg),in Australia显示文摘 | English L J Maguire G B Ward R B | 2000 | Aquaculture2000，187，： | 1 |
| 19 | Laboratory-directed protein evolution显示文摘 | Yuan L Kurek I English J | 2005 | Microbiology and Molecular Biology Reviews2005，69，3： | 1 |
| 20 | Genetic improvement of the Pacific oyster Crassostrea gigas(Thunberg)in Australia显示文摘 | Ward R D English L J McGoldrick D J Maguire G B Nell J A Thompson P A | | 0，，1： | 1 |
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