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您的检索式：作者名="Nick English"
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| 1 | Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer显示文摘Inflammatory bowel diseases are characterised by inflammation that compromises the integrity of the epithelial barrier. The intestinal epithelium is not only a static barrier but has evolved complex mechanisms to control and regulate bacterial interactions with the mucosal surface. Apical tight junction proteins are critical in the maintenance of epithelial barrier function and control of paracellular permeability. The characterisation of alterations in tight junction proteins as key players in epithelial barrier function in inflammatory bowel diseases is rapidly enhancing our understanding of critical mechanisms in disease pathogenesis as well as novel therapeutic opportunities. Here we give an overview of recent literature focusing on the role of tight junction proteins, in particular claudins, in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer. | Jonathan Landy Emma Ronde Nick English Sue K Clark Ailsa L Hart Stella C Knight Paul J Ciclitira Hafid Omar Al-Hassi | 2016 | World Journal of Gastroenterology2016，22，11： | 39 |
| 2 | 瑞士在裁员:瑞银的失败显示文摘昨天(10月30日)一路颠簸赶往伦敦利物浦街附近瑞银办公室上班的银行家们根本没指望这一天会有多开心,但他们可能未曾料到出入证会不再有效,而且会有人指引他们经过一条不常走的路线前往四楼,这是人力资源部的办公地点.大事不妙.
瑞银昨天确认将裁减1万个职位,其中约2000个职位在伦敦.瑞银这个机构闻名于世,一度备受尊崇,它的故事就发生在我们这个时代,从中或许可以得出这样一个简短的格言:银行和交易并不相容.新兴赚钱行当终究不敌传统赚钱行当,一贯如此. | Simon English Nick Goodway 惠钧 | 2013 | 英语文摘2013，，1： | 1 |
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