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| 1 | Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer显示文摘Inflammatory bowel diseases are characterised by inflammation that compromises the integrity of the epithelial barrier. The intestinal epithelium is not only a static barrier but has evolved complex mechanisms to control and regulate bacterial interactions with the mucosal surface. Apical tight junction proteins are critical in the maintenance of epithelial barrier function and control of paracellular permeability. The characterisation of alterations in tight junction proteins as key players in epithelial barrier function in inflammatory bowel diseases is rapidly enhancing our understanding of critical mechanisms in disease pathogenesis as well as novel therapeutic opportunities. Here we give an overview of recent literature focusing on the role of tight junction proteins, in particular claudins, in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer. | Jonathan Landy Emma Ronde Nick English Sue K Clark Ailsa L Hart Stella C Knight Paul J Ciclitira Hafid Omar Al-Hassi | 2016 | World Journal of Gastroenterology2016，22，11： | 39 |
| 2 | 论思维和STEM教育显示文摘随着全球化的STEM教育领域的迅速发展,各国对跨学科研究以及开发更新、更深入的STEM教育的学术研究的呼声也越来越高.文章聚焦思维这个话题,首先从历史发展的视角,简要概括分析了有关思维的不同观点,包括哲学的、心理的和学科的,揭示了思维概念和研究的历史传承.但在新兴的STEM教育背景下,思维需要重新概念化.文章提出了思维是多元的观点,初步探讨了STEM融合教育的这种方式,能够为学生提供充分的机会来有效地发展多元思维模式,并对未来关于思维的研究提出了可能的新研究领域和方向. | 李业平 SCHOENFELD A H DISESSA A A GRAESSER A C BENSON L C ENGLISH L D DUSCHL R A | 2019 | 数学教育学报2019，0，3： | 10 |
| 3 | Suppression of virus accumulation in transgenic plants exhibiting silencing of nuclear gene 显示文摘 | English J J Mueller E Baulcombe D C | 1996 | Plant Cell1996，8，： | 1 |
| 4 | Examining the contribution of glacial till water to storm runoff using two and three-component hy-drograph separations 显示文摘 | Hinton M J Schiff S L English M C | 1994 | Water Resource Research1994，30，： | 1 |
| 5 | Isolation of thermophiles from broadleaf tobacco and effect of pure culture inoculation on cigar aroma and mildness显示文摘 | English C F Bell E J Berger A J | 1967 | Application Microbiology1967，15，： | 1 |
| 6 | The role of platelet-activating factor in regional myocardial ischemiareperfusion injury显示文摘 | Qayumi A K English J C Godin D V | 1998 | Arm Thorac Surg1998，65，： | 1 |
| 7 | Enhancing and tuning pho- non transport at vibrationally mismatched solid-solid interfhces显示文摘 | English T S Duda J C Smoyer J L | 2012 | Physics Review B2012，85，03： | 1 |
| 8 | Development of anodes for a]u- minum/air batteries solution phase inhibition of corrosion 显示文摘 | Macdonald D D English C | 1990 | Journal of Applied Electrochemistry1990，20，3： | 1 |
| 9 | Survey manual for tropical marine resources显示文摘 | ENGLISH S WILKINSON C BAKER V | 1997 | Townsville: Australian Institute of Marine Science1997，，5： | 1 |
| 10 | Isolation of thermophiles from brood leaf tobacco and effect of pure ulture inoculation on cigar aroma and mildness显示文摘 | English C F Bell E J Berger A J | 1967 | Ape Microbio1967，，15： | 1 |
| 11 | A geographic information system-based modeling system for evaluating the cost of delivered energy crop feedstock显示文摘 | Graham R L English B C Noon C E | 2000 | Biomass and Bioenergy2000，18，4： | 1 |
| 12 | Shielding Factors from Wind-Tunnel Studies of Prismatic Structures显示文摘 | English E C | 1990 | Journal of Wind Engineering and Industrial Aerodynamics1990，36，： | 1 |
| 13 | Geochemical composition, phosphorus speciation and mass transport of fine-grained sediment in two Lake Erie tributaries显示文摘 | Stone M English M C 1993 | 1993 | Hydrobiologia1993，253，： | 1 |
| 14 | RheologyAnd photo-cross-linking of thiol-ene polymers 显示文摘 | Bor-Sen C English R J SaadA K | 1996 | Macromolecules1996，29，16： | 1 |
| 15 | Chemose-lective hydrogenation of unsaturated carbanyl-compounds over group-8 and group-9 titania-supported metal catalyst 显示文摘 | Raa C G English M Marinelli T B L W | 1993 | Stud Surf Sci Catal1993，78，： | 1 |
| 16 | Simultaneous Tc-99/Tl-201 imaging using energy-based estimation of the spatial distributions of contaminant photos显示文摘 | Moore Stephen C English Robert J Syravanh Chanh | 1995 | IEEE Transactions on Nuclear Science1995，42，： | 1 |
| 17 | Developmem of anodes for alu- minium/air bakeries- solution phase inhibition of corrosion 显示文摘 | Macdonald D D English C | 1990 | J Appl Electrochem1990，20，： | 1 |
| 18 | Isolation of thermopiles from roadleaftobacco and effect of pure culture inoculation on cigar aroma and mildness显示文摘 | ENGLISH C F BELL E J BERTER A J | 1967 | Appl Envirorr Miembio1967，15，1： | 1 |
| 19 | Radiation - induced segregation in metals显示文摘 | English C A Murphy S M Perks J M | 1990 | J Chem Soc Faraday Tram1990，86，8： | 1 |
| 20 | Development of anodes of aluminium/air batteries-solution phase inhibition of corrosion 显示文摘 | MACDONALD D D ENGLISH C | 1990 | Journal of Applied Electrochemistry1990，20，： | 1 |
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