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| 1 | Effect of alternative antibiotics in treatment of cefotaxime resistant spontaneous bacterial peritonitis显示文摘AIM:To evaluate effective alternative antibiotics in treatment of cefotaxime-resistant spontaneous bacterial peritonitis.METHODS:One hundred cirrhotic patients with spontaneous bacterial peritonitis [ascitic fluid polymorphonuclear cell count(PMNLs) ≥ 250 cells/mm 3 at admission] were empirically treated with cefotaxime sodium 2 g/12 h and volume expansion by intravenous human albumin.All patients were subjected to history taking,complete examination,laboratory tests(including a complete blood cell count,prothrombin time,biochemical tests of liver and kidney function,and fresh urine sediment),chest X-ray,a diagnostic abdominal paracentesis,and the sample subjected to total and differential cell count,chemical examination,aerobic and anaerobic cultures.Patients were divided after 2 d by a second ascitic PMNL count into group Ⅰ;patients sensitive to cefotaxime(n = 81),group Ⅱ(n = 19);cases resistant to cefotaxime(less than 25% decrease in ascitic PMNL count).Patients of group Ⅱ were randomly assigned into meropenem(n = 11) or levofloxacin(n = 8) subgroups.All patients performed an end of treatment ascitic PMNL count.Patients were considered improved when:PMNLs decreased to < 250 cells/mm 3,no growth in previously positive culture cases,and improved clinical manifestations with at least 5 d of antibiotic therapy.RESULTS:Age,sex,and Child classes showed no significant difference between group Ⅰ and group Ⅱ.Fever and abdominal pain were the most frequent manifestations and were reported in 82.7% and 80.2% of patients in group Ⅰ and in 94.7% and 84.2% of patients in group Ⅱ,respectively.Patients in group Ⅱ had a more severe ascitic inflammatory response than group Ⅰ and this was demonstrated by more ascitic lactate dehydrogenase(LDH) [median:540 IU/L(range:150-1200 IU/L) vs median:240 IU/L(range:180-500 IU/L),P = 0.000] and PMNL [median:15 000 cell/mm 3(range:957-23 822 cell/mm 3) vs 3400 cell/mm 3(range:695-26 400 cell/mm 3),P = 0.000] counts.Ascitic fluid culture was positive in 32% of cases.Cefotaxime failed in 19% of patients;of these patients,11(100%) responded to meropenem and 6(75%) responded to levofloxacin.Two patients with failed levofloxacin therapy were treated according to the in vitro culture and sensitivity(one case was treated with vancomycin and one case was treated with ampicillin/sulbactam).In group Ⅱ the meropenem subgroup had higher LDH(range:108-860 IU/L vs 120-491 IU/L,P = 0.042) and PMNL counts(range:957-23 822 cell/mm 3 vs 957-15 222 cell/mm 3,P = 0.000) at initiation of the alternative antibiotic therapy;there was no significant difference in the studied parameters between patients responsive to meropenem and patients responsive to levofloxacin at the end of therapy(mean ± SD:316.01 ± 104.03PMNLs/mm 3 vs 265.63 ± 69.61 PMNLs/mm 3,P = 0.307).The isolated organisms found in group Ⅱ were;enterococci,acinetobacter,expanded-spectrum β-lactamase producing Escherichia coli,β-lactamase producing Enterobacter and Staphylococcus aureus.CONCLUSION:Empirical treatment with cefotaxime is effective in 81% of cases;meropenem is effective in cefotaxime-resistant cases. | Ahmed Abouelkhair Badawy Tarik Ibrahim Zaher Samar Mahmoud Sharaf Mohamed Hassan Emara Noha Elsaid Shaheen Talaat Fathy Aly | 2013 | World Journal of Gastroenterology2013，19，8： | 13 |
| 2 | A review on zero energy buildings-Pros and cons显示文摘Enhancing the energy efficiency of structures has been a staple of energy policies.The key goal is to slash elec-tricity usage in order to minimize the footprint of houses.This goal is sought by putting restrictions on the design specifications with respect to the properties of the raw materials and components as well as the exploitation of sustainable sources of energy.These facts for the basis for zero-energy building(ZEB)being established.This novel technology has faced several obstacles impeding its commercialization and future advancement.This inves-tigation therefore holistically explored and evaluated the state of zero energy building and factors impeding their commercialization.The review further proposed some suggestion in terms of technology that can be considered by the sector to augment existing technologies.Similarly,the investigation touched on the effect of occupant’s character in zero energy structures.Policies in terms of government subsidies and tax rebates were recommended to encourage more investors into the sector.Finally,the perception of zero energy building being more expensive compared to the traditional structures can equally be curbed via efficient and effective public sensitization. | Tabbi Wilberforce A.G.Olabi Enas Taha Sayed Khaled Elsaid Hussein M.Maghrabie Mohammad Ali Abdelkareem | 2023 | Energy and Built Environment2023，4，1： | 3 |
| 3 | The role of graft reperfusion sequence in the development of non-anastomotic biliary strictures following orthotopic liver transplantation: A meta-analysis显示文摘Background: Liver transplant is a potential cure for liver failure and hepatic malignancy but there are many techniques which have been described for vascular reconstruction. This study was to compare the prevalence of non-anastomotic biliary stricture and other surgical complications based on Clavien-Dindo scoring system, in initial portal reperfusion(sequential) versus simultaneous or initial artery reperfusion. Data sources: Meta-analysis of published studies comparing the outcomes of both techniques was carried out. Data search was conducted across the major databases and studies were selected under the guidance of the Cochrane guidelines for systematic reviews and meta-analysis. Results: Seven studies were included to address the primary and the secondary outcomes. No statistical difference was found in the incidence of non-anastomotic biliary strictures(OR = 0.40; P = 0.14), regardless of reperfusion technique. The pooled estimate of the Clavien-Dindo grading of complications was not significantly different between the techniques, though Clavien-Dindo II complications were higher in the simultaneous or initial artery reperfusion group than the initial portal reperfusion group(OR = 2.73; P = 0.01). Similarly, there was no difference in the operative time, hospital stay and other outcomes addressed in this report. Conclusions: The available evidence suggests that there is no significant difference demonstrated in the rate of non-anastomotic biliary strictures or other complications, between the two techniques, except for Clavien-Dindo II complications. | Mohamed Bekheit Matteo Catanzano Stuart Shand Irfan Ahmed ELSaid ELKayal Gihan Mohamed Shehata Adel Zaki | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，1： | 2 |
| 4 | Dynamical behavior, chaos control and synchronization of a memristor-based ADVP circuit 显示文摘 | El-sayed A M A Elsaid A Nour H M | 2013 | Communications in Nonlinear Science and Numerical Simulation2013，18，1： | 1 |
| 5 | Language Choice Online: Globalization and Identity in Egypt显示文摘 | MarkWarschauer Ghada R. ElSaid Ayman G.Zohry | 2006 | Journal of Computer‐Mediated Communication2006，，4： | 1 |
| 6 | Effects of water extracts of thyme (Thymus vulgaris) and ginger (Zingiber officinale Roscoe) on alcohol abuse显示文摘 | Shati A A Elsaid F G | 2009 | Food and Chemical Toxicology2009，47，： | 1 |
| 7 | Animal models of os-teoarthritis: challenges of model selection and analysis显示文摘 | Teeple E Jay GD Elsaid KA | 2013 | The AAPS Journal2013，15，2： | 1 |
| 8 | Sandhoff disease ( GM2 Gangliosidoses) in apremature patient with bronchopulmonary dysplasia显示文摘 | ABDUL-WAHAB A BESSISSO M S ELSAID MF | 2002 | Saudi Med J2002，23，5： | 1 |
| 9 | Whole genome sequencing identifies a novel occludin mutation in microcephaly with band-like calcification and polymicrogyria that extends the phenotypic spectrum显示文摘 | Elsaid MF Kamel H Chalhoub N | | 0，，： | 1 |
| 10 | Age,CEO Succession,and Risk Taking显示文摘 | ELSAID E URSEL N D | 2012 | Accounting and Finance Re-search2012，1，2： | 1 |
| 11 | Association of articular cartilage degradation and loss of boundary-lubricating ability of synovial fluid following injury and inflammatory arthritis显示文摘 | Elsaid KA Jay GD Warman ML | | 0，，6： | 1 |
| 12 | Decreased lubricin concentrations and markers of joint inflammation in the synovial fluid of patients with anterior cruciate ligament injury显示文摘 | Elsaid KA Fleming BC Oksendahl HL | | 0，，6： | 1 |
| 13 | Oxygen desaturation index from nocturnal oximetry:A sensitive and specific tool to detect sleep-disordered breathing in surgical patients 显示文摘 | Chung F Liao P Elsaid H | 2012 | Anesth Analg2012，14，5： | 1 |
| 14 | Open-label safety and efficacy pilot trial of intraperitoneal bevacizumab as pal- liative treatment in refractory malignant ascites 显示文摘 | E1 Shami K Elsaid A E1 Kerm Y | 2007 | J Clin Oneol2007，25，18： | 1 |
| 15 | Dynamical behavior, chaos control and synchronization显示文摘 | EI-SAYED A M A ELSAID A NOUR H M | 2013 | Communication in Nonlinear Science and NumericalSimulation2013，18，1： | 1 |
| 16 | Non-truncating LIFR mutation:causal for prominent congenital pain insensitivity phenotype with progressive vertebral destruction?显示文摘 | Elsaid MF Chalhoub N Kamel H | 2015 | Clin Genet2015，89，： | 1 |
| 17 | Open-label safety and efficacy pilot trial of intraperitoneal bevacizumab as palliative treatment in refractory malignant ascites显示文摘 | El-Shami K Elsaid A El-Kerm Y | | 0，，： | 1 |
| 18 | Reduced expression and proteolytic susceptibility of lubricin/superficial zone protein may explain early elevation in the coefficient of friction in the joints of rats with antigen-induced arthritis显示文摘 | Elsaid KA Jay GD Chichester CO | 2007 | Arthritis Rheum2007，56，1： | 1 |
| 19 | Protection against toxoplasmosis in mice immunized with different antigens of Toxoplasma gondii incorporated into liposomes显示文摘 | Elsaid MMA Vitor RWA Frézard FJG | 1999 | Mem Inst Oswaldo Cruz1999，94，4： | 1 |
| 20 | Association of polymorphisms G(-174) C in IL-6 gene and G(-1082 )A in IL-10 gene with traditional cardiovascular risk factors in patients with coronary artery disease显示文摘 | Elsaid A Abdel-Aziz AF Elmougy R | 2014 | In- dian J Biochem Biophys2014，51，4： | 1 |
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