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| 1 | Intraocular pressure elevation after intravitreal triamcinolone acetonide injection: a Meta-analysis显示文摘AIM:To report on intraocular pressure(IOP)after intravitreal injections of triamcinolone acetonide.·METHODS:Systematic literature review of studies that investigated the effects of an injection of triamcinolone Intravitreal triamcinolone acetonide on IOP was conducted according to the Cochrane Collaboration methodology and the reported effects have been analyzed with Meta-analysis.·RESULTS:We found that the IOP follows an inverted-U shape pattern over time starting with an average value of14.81±1.22 mm Hg before the injection,rising to a maximum of 19.48±2.15 mm Hg after one month of injection and falling down to 16.16±1.92 mm Hg after6mo.Moreover,country of study,age,previous history of glaucoma and gender compositions matter for crossstudy were different in reported IOP changes.·CONCLUSION:Our findings may be helpful in determining pressure elevation risk of intravitreal triamcinolone acetonide therapy as well as comparing it with those of more recent therapies such as the antivascular endothelial growth factor agents. | Cansu Yuksel-Elgin Ceyhun Elgin | 2016 | International Journal of Ophthalmology(English edition)2016，9，1： | 6 |
| 2 | Comparison of autofluorescence and optical coherence tomography findings in acute and chronic central serous chorioretinopathy显示文摘AIM:To discuss and compare the fundus autofluorescence(FAF)and optical coherence tomography(OCT)in acute or chronic central serous chorioretinopathy(CSCR).METHODS:Medical records of 100 cases of CSCR were reviewed.Acute and chronic cases were evaluated according to the duration of decreased visual acuity,serous retinal detachment(RD)and focal leakage on fluorescein angiography(FA).Chi-square test was used for statistical analysis.RESULTS:Forty cases had acute and 60 cases had chronic CSCR.FAF showed focal hypo-autofluorescence in 34(85%)and iso-autofluorescence in 6(15%)of acute cases and hypo-autofluorescence in 51(85%),hyperautofluorescence in 6(10%)and iso-autofluorescence in3(5%)of chronic cases.OCT showed serous RD with distinct borders correlated with FAF findings(hypoautofluorescence)in all acute CSCR cases.In chronic CSCR group,OCT showed serous RD with indistinct borders correlated with FAF findings.The differences between the OCT and FAF findings of the two groups were significant(P=0.000).CONCLUSION:OCT and FAF findings can support the clinical observations in differential diagnosis of acute and chronic CSCR and help clinicians to evaluate retinal pigment epithelium,outer segments of photoreceptors and the components of serous RD. | Mehmet Yasin Teke Ufuk Elgin Pinar Nalcacioglu-Yuksekkaya Emine Sen Pinar Ozdal Faruk Ozturk | 2014 | International Journal of Ophthalmology(English edition)2014，7，2： | 4 |
| 3 | Comparison of total/active ghrelin levels in primary open angle glaucoma,pseudoexfoliation glaucoma and pseudoexfoliation syndrome显示文摘AIM:To investigate the levels of ghrelin(Gh),acylated ghrelin(AGh) and AGh/Gh ratio in the humor aqueous(HA) of cases with pseudoexfoliation syndrome(PXS),pseudoexfoliation glaucoma(PXG),primary open angle glaucoma(POAG) and to compare these with control subjects.METHODS:A prospective examination was made of the total Gh,and AGh levels in HA of 67 patients undergoing cataract surgery.Patients were divided into 4 groups.HA samples were aspirated at the beginning of the surgery,stored at -70℃.Gh and AGh quantification was performed with ELISA kits and the AGh/total-Gh ratios were calculated.ANOVA,Kruskal-Wallis,Chi-square and post-hoc tests were used for statistical analysis.RESULTS:Total Gh levels in HA were 189.2±45.6 pg/mL in the control group,199.2±32.9 pg/mL in PXS,180.6±20.9 pg/mL in PXG and 176.8±21.4 pg/mL in POAG groups(P>0.05).AGh levels in HA were 23.09±5.01 pg/mL in the control group,24.13±5.22 pg/mL in PXS,22.29±1.55 pg/m L in PXG and 19.69±2.93 pg/mL in POAG groups(P>0.05).The ratio of AGh/Gh was 10.3%±2.34% in the control group,13.03%±2.58% in PXS,12.3%±1.54% in PXG and 11.79%±1.41% in POAG groups(P=0.044).The difference between the PXS and control groups was significant(P=0.03).CONCLUSION:In spite of statistically insignificant results,the HA total Gh levels were lower than those of the control subjects but not parallel with the AGh levels in glaucoma patients.The relative increase in the AGh/Gh ratio in glaucoma cases supports the view that proportional increases of AGh might play a role in the pathogenesis of glaucoma. | Numan Eraslan Ufuk Elgin Emine Sen Aytul Kilic Pelin Yilmazbas | 2018 | International Journal of Ophthalmology(English edition)2018，11，5： | 3 |
| 4 | The role of 18F-FDG PET/CT in detecting colorectal cancer recurrence in patients with elevated CEA levels显示文摘 | Elgin Ozkan Cigdem Soydal Mine Araz Kemal Metin Kir Erkan Ibis | 2012 | Nuclear Medicine Communications2012，，4： | 2 |
| 5 | Conjunctival impression cytology in non-proliferative and proliferative diabetic retinopathy显示文摘AIM:To examine the integrity of the ocular surfaces of subjects with and without diabetes with no conjunctival and dry eye signs and symptoms and compare conjunctival impression cytology findings in diabetics with non-proliferative and proliferative diabetic retinopathy.METHODS:Conjunctival impression cytology was performed on 43 eyes of 43 subjects with nonproliferative diabetic retinopathy(NPDR),42 eyes of 42subjects with proliferative diabetic retinopathy(PDR),and30 eyes of 30 control subjects.Impression cytology specimens of each group were graded and scored in the range 0-3 according to Nelson's method.RESULTS:There were 45(52.9%)women and 40(47.1%)men.The mean age of the patients was 59.6±9.3y(range,43-76y)in NPDR group and 58.0±8.8y(range,41-85y)in PDR group.Cases with NPDR and PDR showed statistically significant higher impression cytology scores than control group(P<0.05).There was no difference between the NPDR and PDR patients for impression cytology grading scores.CONCLUSION:It is determined that impression cytology grades are altered in patients with NPDR and PDR.Consequently,we suggest that there might be an association between the impression cytology grading scores and the severity of diabetic | Mehmet Citirik Nilufer Berker Hulya Haksever Ufuk Elgin Huseyin Ustun | 2014 | International Journal of Ophthalmology(English edition)2014，7，2： | 2 |
| 6 | Glaucoma and in- creased central corneal thickness in aphakic and pseudophakic patients after congenital cataract surgery显示文摘 | Simsek T Mutluay AH Elgin U | 2006 | Br J Ophthalmol2006，90，9： | 1 |
| 7 | Transcription and RNA inter- ference in the formation of heterochromatin显示文摘 | GREWAL S I S ELGIN S C R | 2007 | Nature2007，447，7143： | 1 |
| 8 | Small RNA-directed heterochroma- tin formation in the context of deve|opment:what flies might learn from fission yeast显示文摘 | Huisinga K L Elgin S C | 2009 | Biochim Biophys Acta2009，1789，1： | 1 |
| 9 | Trabeculectomy with mitomycin C combined with direct cauterization of peripheral iris in the management of neovascular glaucoma显示文摘 | Elgin U Beerker N Batman A | 2006 | J Glaucoma2006，15，5： | 1 |
| 10 | Epigenetic codes for heterochromatin formation and silencing:rounding up the usual suspects显示文摘 | Richards E J Elgin S C | 2002 | Cell2002，108，： | 1 |
| 11 | The HP1 protein family:getting a grip on chromatin显示文摘 | Eissenberg JC Sarah CR Elgin | | 0，，02： | 1 |
| 12 | Relationship between central corneal thickness and parameters of optic nerve head topography in healthy subjects 显示文摘 | Cankaya AB Elgin U Batman A | 2008 | Eur J Ophthalmol2008，18，1： | 1 |
| 13 | Incidence of secondary glaucoma in behcet disease显示文摘 | Elgin U Berker N Batman A | | 0，，： | 1 |
| 14 | Production of antibodies using proteins in gel bands 显示文摘 | Amero SA James TC Elgin SC | 1994 | Methods Mol Biol1994，32，： | 1 |
| 15 | Transcription and RNA interference inthe formation of heterochromatin显示文摘 | Grewal S 1 Elgin S C | 2007 | Nature2007，447，7143： | 1 |
| 16 | Transcription and RNA interference in the formation of heterochromatin显示文摘 | GREWAL SI ELGIN SC | 2007 | Nature2007，447，7143： | 1 |
| 17 | Denying a Dualism: Goodman's Repudiation of the Analytic/Synthetic Distinction显示文摘 | Elgin C Z | 2004 | Midwest Studies in Philosophy2004，28，： | 1 |
| 18 | Design of a High-Speed Space Modern for the Lunar Laser Communications Demonstration显示文摘 | CONSTANTINE S ELGIN L E | 2011 | SPIE2011，7923，： | 1 |
| 19 | Relationship of spectral data to grain yield variation显示文摘 | Tucker C J Holben B N Elgin Jr J H | 1980 | Photogrammetric Engineering and Remote Sensing1980，46，5： | 1 |
| 20 | Trabeeulectomy with mito- myein C combined with direet cauterization of peripheral iris in the management of neovaseular glaucoma 显示文摘 | Elgin U Berker N Batman A | 2006 | J Glaucoma2006，15，5： | 1 |
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