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| 1 | Human papillomavirus in esophageal squamous cell carcinoma in Colombia and Chile显示文摘AIM: To examine the presence of human papillomavirus (HPV) in esophageal squamous cell carcinoma (ESCC) specimens collected from Colombia and Chile located in the northern and southern ends of the continent, respectively. METHODS: We examined 47 and 26 formalin-fixed and paraffin-embedded ESCC specimens from Colombia and Chile, respectively. HPV was detected using GP5+/GP6+ primer pair for PCR, and confirmed by Southern blot analysis. Sequencing analysis of L1 region fragment was used to identify HPV genotype. In addition, P16INK4A protein immunostaining of all the specimens was conducted. RESULTS: HPV was detected in 21 ESCC specimens (29%). Sequencing analysis of L1 region fragment identified HPV-16 genome in 6 Colombian cases(13%) and in 5 Chilean cases (19%). HPV-18 was detected in 10 cases (21%) in Colombia but not in any Chilean case. Since Chilean ESCC cases had a higher prevalence of HPV-16 (without statistical significance), but a significantly lower prevalence of HPV-18 than in Colombian cases (P = 0.011) even though the two countries have similar ESCC incidence rates, the frequency of HPV-related ESCC may not be strongly affected by risk factors affecting the incidence of ESCC. HPV-16 genome was more frequently detected in p16 positive carcinomas, although the difference was not statistically significant. HPV-18 detection rate did not show any association with p16 expression. Well-differentiated tumors tended to have either HPV-16 or HPV-18 but the association was not statistically significant. HPV genotypes other than HPV-16 or 18 were not detected in either country. CONCLUSION: HPV-16 and HPV-18 genotypes can be found in ESCC specimens collected from two South American countries. Further studies on the relationship between HPV-16 presence and p16 expression in ESCC would aid understanding of the mechanism underlying the presence of HPV in ESCC. | Andres Castillo Francisco Aguayo Chihaya Koriyama Miyerlandi Torres Edwin Carrascal Alejandro Corvalan Juan P Roblero Cecilia Naquira Mariana Palma Claudia Backhouse Jorge Argandona Tetsuhiko Itoh Karem Shuyama Yoshito Eizuru Suminori Akiba | 2006 | World Journal of Gastroenterology2006，12，38： | 11 |
| 2 | Navigated liver surgery:State of the art and future perspectives显示文摘Background:In recent years,the development of digital imaging technology has had a significant influence in liver surgery.The ability to obtain a 3-dimensional(3D)visualization of the liver anatomy has provided surgery with virtual reality of simulation 3D computer models,3D printing models and more recently holograms and augmented reality(when virtual reality knowledge is superimposed onto reality).In addition,the utilization of real-time fluorescent imaging techniques based on indocyanine green(ICG)uptake allows clinicians to precisely delineate the liver anatomy and/or tumors within the parenchyma,applying the knowledge obtained preoperatively through digital imaging.The combination of both has transformed the abstract thinking until now based on 2D imaging into a 3D preoperative conception(virtual reality),enhanced with real-time visualization of the fluorescent liver structures,effectively facilitating intraoperative navigated liver surgery(augmented reality).Data sources:A literature search was performed from inception until January 2021 in MEDLINE(Pub Med),Embase,Cochrane library and database for systematic reviews(CDSR),Google Scholar,and National Institute for Health and Clinical Excellence(NICE)databases.Results:Fifty-one pertinent articles were retrieved and included.The different types of digital imaging technologies and the real-time navigated liver surgery were estimated and compared.Conclusions:ICG fluorescent imaging techniques can contribute essentially to the real-time definition of liver segments;as a result,precise hepatic resection can be guided by the presence of fluorescence.Furthermore,3D models can help essentially to further advancing of precision in hepatic surgery by permitting estimation of liver volume and functional liver remnant,delineation of resection lines along the liver segments and evaluation of tumor margins.In liver transplantation and especially in living donor liver transplantation(LDLT),3D printed models of the donor’s liver and models of the recipient’s hilar anatomy can contribute further to improving the results.In particular,pediatric LDLT abdominal cavity models can help to manage the largest challenge of this procedure,namely large-for-size syndrome. | Paschalis Gavriilidis Bjørn Edwin Egidijus Pelanis Ernest Hidalgo Nicola de’Angelis Riccardo Memeo Luca Aldrighetti Robert P Sutcliffe | 2022 | Hepatobiliary & Pancreatic Diseases International2022，21，3： | 6 |
| 3 | Chemical Coal Cleaning Using Selective Oxidation显示文摘 | Stephen R P Edwin J H Xavier A D | 1994 | Fuel1994，73，2： | 1 |
| 4 | Long-term morphodynamic evolution of Texel inlet and its ebb-tidal delta, the Netherlands 显示文摘 | EDWIN P L van DERSPEK J F | 2006 | Marine Geology2006，225，1： | 1 |
| 5 | Observation of a non-constant mean curvature interface in an ABC tribloek copolymer显示文摘 | Samuel P Gido Dwight W Schwark Edwin L Thomas | 1993 | Macromolecules1993，26，： | 1 |
| 6 | Structural Features of Alkylphenolic Chemicals Associated with Estrogenic Activity显示文摘 | Edwin J Routledge John P Sumpter | 1997 | The American Society for Biochemistry and Molecular Biology1997，272，6： | 1 |
| 7 | A utility-based power-control scheme in wireless cellular systems显示文摘 | Xiao M Shroff N B Edwin K P | 2003 | IEEE/ACM Trans Networking2003，11，2： | 1 |
| 8 | Effect of sputtering parameters on Ta coatings for gun bore applica- tions 显示文摘 | Mastson Dean W McClanahan Edwin D Rice J P | 2000 | Surface and Coatings Technology2000，，： | 1 |
| 9 | Facial gender classification using shape-from-shading 显示文摘 | Wu J William A P Edwin R | 2010 | Image and Vision Computing2010，28，6： | 1 |
| 10 | The relationship between circulating 25-hydroxyvitamin D and survival in newly diagnosed advanced non-small-cell lung cancer显示文摘 | Vashi PG Edwin P Popiel B | 2015 | BMC cancer2015，15，： | 1 |
| 11 | The JPL telerobot teleoperation system 显示文摘 | EDWIN P K EDMUND A | 1990 | International Journal of Robotics and Automation1990，5，1： | 1 |
| 12 | Short-range quantitative precipitation forecasting in Hong Kong显示文摘 | P W Li Edwin S T Lai | 2004 | Journal of Hydrology2004，，288： | 1 |
| 13 | Predictors and outcomes of job search behavior:The moderating eVects of gender and family situation显示文摘 | Edwin A.J Van Hooft M P B T | | 0，，： | 1 |
| 14 | Routing trains through railway stations: complexity issues 显示文摘 | Kroon L G Edwin Romeijn H Zwaneveld P J | 1997 | European Journal of Operational Research1997，98，3： | 1 |
| 15 | Renal impairment and heart failure with preserved ejection fraction early post-myocardial infarction显示文摘AIM:To study if impaired renal function is associated with increased risk of peri-infarct heart failure (HF) in patients with preserved ejection fraction (EF).METHODS:Patients with occluded infarct-related arteries (IRAs) between 1 to 28 d after myocardial infarction (MI) were grouped into chronic kidney disease (CKD) stages based on estimated glomerular filtration rate (eGFR).Rates of early post-MI HF were compared among eGFR groups.Logistic regression was used to explore independent predictors of HF.RESULTS:Reduced eGFR was present in 71.1% of 2160 patients,with significant renal impairment (eGFR < 60 mL/min every 1.73 m2) in 14.8%.The prevalence of HF was higher with worsening renal function:15.5%,17.8% and 29.4% in patients with CKD stages 1,2 and 3 or 4,respectively (P < 0.0001),despite a small absolute difference in mean EF across eGFR groups:48.2 ± 10.0,47.9 ± 11.3 and 46.2 ± 12.1,respectively (P=0.02).The prevalence of HF was again higher with worsening renal function among patients with preserved EF:10.1%,13.6% and 23.6% (P < 0.0001),but this relationship was not significant among patients with depressed EF:27.1%,26.2% and 37.9% (P= 0.071).Moreover,eGFR was an independent correlate of HF in patients with preserved EF (P=0.003) but not in patients with depressed EF (P=0.181).CONCLUSION:A significant proportion of post-MI patients with occluded IRAs have impaired renal function.Impaired renal function was associated with an increased rate of early post-MI HF,the association being strongest in patients with preserved EF.These findings have implications for management of peri-infarct HF. | Vinod Jorapur Gervasio A Lamas Zygmunt P Sadowski Harmony R Reynolds Antonio C Carvalho Christopher E Buller James M Rankin Jean Renkin Philippe Gabriel Steg Harvey D White Carlos Vozzi Eduardo Balcells Michael Ragosta C Edwin Martin Vankeepuram S Srinivas William W Wharton III Staci Abramsky Ana C Mon Shari S Kronsberg Judith S Hochman | 2010 | World Journal of Cardiology2010，2，1： | 1 |
| 16 | Determining the crystal structure of cellulose ⅢⅠ by modeling显示文摘 | Zakhia M Ford Edwin D Stevens Glenn P Johnson | 2005 | Carbohydrate Research2005，340，： | 1 |
| 17 | Fuzzy precompensated PID controllers显示文摘 | Kim J H Kim K C Chong Edwin K P | 1994 | IEEE Transactions on Control Systems Technology1994，2，4： | 1 |
| 18 | New strategy for comprehensive analysis of polybrominated diphenyl ethers,polychlorinated dibenzo-p-dioxins,polychlorinated diben-zofurans and polychlorinated biphenyls by gas chromatogra-phy coupled with mass spectrometry显示文摘 | Pirard C Edwin D P Jean J J | 2003 | Journal of Chro-matography A2003，998，： | 1 |
| 19 | Lignin depolymerization in hydrogen-donor solvents显示文摘 | Edwin D Marieke K Didier P | 1999 | Holzforschung1999，53，6： | 1 |
| 20 | Lignin depolymerization in hydrogen-donor solvents显示文摘 | Edwin D Marieke K Didier P | 1999 | Holzforschung1999，53，6： | 1 |
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