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| 1 | MRI-determined fat content of human liver,pancreas and kidney显示文摘AIM:To assess and correlate the lipid content of various organs in obese subjects and in persons with a normal body weight.METHODS:Magnetic resonance spectroscopy and a previously validated gradient echo magnetic resonance imaging method with Dixon's two point technique were used in this study to quantify fat in liver,pancreas as well as kidney.RESULTS:In 36 volunteers with body mass index(BMI) ranging from 20.0 to 42.9 kg/m2,the median fat content of liver,pancreas and kidney was 2.3%(interquartile range:0.2%-7.8%),2.7%(1.0%-6.5%) and 0.7%(0.1%-1.4%),respectively.BMI and subcutaneous fat correlated significantly with liver and pancreas fat content.We show for the first time the significant correlation of liver and pancreas fat content in healthy controls(r = 0.43,P < 0.01).These observations are related to body weight as measured by BMI and the amount of subcutaneous fat.Kidney fat content is very low and correlates with none of the other fat depots.CONCLUSION:Renal lipid accumulation,unlike the coupled accumulations of fat in liver and pancreas,is not observed in obese subjects.Unlike suggestions made in previous studies,renal lipid accumulation appears not to be involved in the pathogenesis of renal disease in humans. | Paul E Sijens Mireille A Edens Stephan JL Bakker Ronald P Stolk | 2010 | World Journal of Gastroenterology2010，16，16： | 14 |
| 2 | 论企业承担社会责任的“四个结合”显示文摘 | 刘凤军 Eden Yin | 2007 | 经济研究参考2007，，30： | 12 |
| 3 | The Transforming Growth Factor-β Superfamily Member Growth-Differentiation Factor-15 Protects the Heart From Ischemia/Reperfusion Injury显示文摘 | Tibor Kempf Matthias Eden Jens Strelau Marian Naguib Christian Willenbockel J?rn Tongers J?rg Heineke Daniel Kotlarz Jian Xu Jeffery D. Molkentin Hans W. Niessen Helmut Drexler Kai C. Wollert | 2006 | Circulation Research2006，，3： | 3 |
| 4 | Infectious causation of chronic disease:Examining the relationship between Giardia lamblia infection and irritable bowel syndrome显示文摘AIM: To evaluate whether a higher prevalence of Giardia lamblia infection is associated with an increase in irritable bowel syndrome (IBS) prescriptions at the county level in Michigan. METHODS: The Michigan Disease Surveillance System (MDSS) was used to ascertain both the numbers of Giardia lamblia infections as well as the total number of foodborne illnesses per population by county in Michigan during 2005. This was compared with Blue Cross Blue Shield (BCBS) of Michigan numbers of drug prescriptions for IBS per one thousand members per county in 2005. These data were also analyzed for associations with per capita income by county and the number of refugees entering each county in 2005. RESULTS: There were a total of 786 confirmed cases of Giardia lamblia reported to MDSS in 2005. During the same time period, the number of prescriptions for IBS varied from 0.5 per 1000 members up to 6.0 per 1000 members per month. There was no trend towards higher numbers of IBS prescriptions in the counties with more Giardia lamblia infections. Per capita income was not associated with either IBS prescriptions or Giardiasis. There was a significant linear association between the number of refugees entering each county, and the number of Giardia lamblia cases per 100 000 population. CONCLUSION: In this ecological study, there was no association found between BCBS prescriptions for IBS and Giardia lamblia infections in Michigan counties. Our findings may have been influenced by the disparate number of refugees admitted per county. | Alice S Penrose Eden V Wells Allison E Aiello | 2007 | World Journal of Gastroenterology2007，13，34： | 3 |
| 5 | Automated Chinese medicinal plants classification based on machine learning using leaf morpho-colorimetry,fractal dimension and visible/near infrared spectroscopy显示文摘The identification of Chinese medicinal plants was conducted to rely on ampelographic manual assessment by experts.More recently,machine learning algorithms for pattern recognition have been successfully applied to leaf recognition in other plant species.These new tools make the classification of Chinese medicinal plants easier,more efficient and cost effective.This study showed comparative results between machine learning models obtained from two methods:i)a morpho-colorimetric method and ii)a visible(VIS)/Near Infrared(NIR)spectral analysis from sampled leaves of 20 different Chinese medicinal plants.Specifically,the automated image analysis and VIS/NIR spectral based parameters obtained from leaves were used separately as inputs to construct customized artificial neural network(ANN)models.Results showed that the ANN model developed using the morpho-colorimetric parameters as inputs(Model A)had an accuracy of 98.3%in the classification of leaves for the 20 medicinal plants studied.In the case of the model based on spectral data from leaves(Model B),the ANN model obtained using the averaged VIS/NIR spectra per leaf as inputs showed 92.5%accuracy for the classification of all medicinal plants used.Model A has the advantage of being cost effective,requiring only a normal document scanner as measuring instrument.This method can be adapted for non-destructive assessment of leaves in-situ by using portable wireless scanners.Model B combines the fast,non-destructive advantages of VIS/NIR spectroscopy,which can be used for rapid and non-invasive identification of Chinese medicinal plants and other applications by analyzing specific light spectra overtones from leaves to assess concentration of pigments such as chlorophyll,anthocyanins and others that are related active compounds from the medicinal plants. | Jinru Xue Sigfredo Fuentes Carlos Poblete-Echeverria Claudia Gonzalez Viejo Eden Tongson Hejuan Du Baofeng Su | 2019 | International Journal of Agricultural and Biological Engineering2019，12，2： | 3 |
| 6 | Rhubarb extract partially improves mucosal integrity in chemotherapy-induced intestinal mucositis显示文摘AIM To investigate the effects of orally gavaged aqueous rhubarb extract(RE) on 5-fluorouracil(5-FU)-induced intestinal mucositis in rats. METHODS Female Dark Agouti rats(n = 8/group) were gavaged daily(1 mL) with water, high-dose RE(HDR; 200 mg/kg) or low-dose RE(LDR; 20mg/kg) for eight days. Intestinal mucositis was induced(day 5) with 5-FU(150 mg/kg) via intraperitoneal injection. Intestinal tissue samples were collected for myeloperoxidase(MPO) activity and histological examination. Xenopus oocytes expressing aquaporin 4 water channels were prepared to examine the effect of aqueous RE on cell volume, indicating a potential mechanism responsible for modulating net fluid absorption and secretion in the gastrointestinal tract. Statistical significance was assumed at P < 0.05 by one-way ANOVA. RESULTS B o d y w e i g h t w a s s i g n i f i c a n t l y r e d u c e d i n r a t s administered 5-FU compared to healthy controls(P < 0.01). Rats administered 5-FU significantly increased intestinal MPO levels(≥ 307%; P < 0.001), compared to healthy controls. However, LDR attenuated this effect in 5-FU treated rats, significantly decreasing ileal MPO activity(by 45%; P < 0.05), as compared to 5-FU controls. 5-FU significantly reduced intestinal mucosal thickness(by ≥ 29% P < 0.001) as compared to healthy controls. LDR significantly increased ileal mucosal thickness in 5-FU treated rats(19%; P < 0.05) relative to 5-FU controls. In xenopus oocytes expressing AQP4 water channels, RE selectively blocked water influx into the cell, induced by a decrease in external osmotic pressure. As water efflux was unaltered by the presence of extracellular RE, the directional flow of water across the epithelial barrier, in the presence of extracellular RE, indicated that RE may alleviate water loss across the epithelial barrier and promote intestinal health in chemotherapy-induced intestinal mucositis.CONCLUSION In summary, low dose RE improves selected parameters of mucosal integrity and reduces ileal inflammation, manifesting from 5-FU-induced intestinal mucositis. | Juliana E Bajic Georgina L Eden Lorrinne S Lampton Ker Y Cheah Kerry A Lymn Jinxin V Pei Andrea J Yool Gordon S Howarth | 2016 | World Journal of Gastroenterology2016，22，37： | 3 |
| 7 | BioLumix快速微生物检测系统:为您节省时间和成本显示文摘美国自2010年6月25日起要求所有的营养保健品企业都必须遵守美国食品与药品管理局(FDA)的动态药品生产管理规范(cGMP)规则。并规定每个生产商必须用"适当的实验设施进行任何有必要的测试和检查以确定:a)所用成分是否符合规定;b)过程规范是否遵守主要生产记录里的规定;c)膳食添加剂生产符合要求。"这就意味着生产企业需采取措施确保产品不受有害微生物污染。 | Ruth Eden 原铨 | 2011 | 食品安全导刊2011，，5： | 2 |
| 8 | Export Duty Rebates and Export Performance: Theory and China’s Experience显示文摘 | Chi-Chur Chao W.L Chou Eden S.H Yu | 2001 | Journal of Comparative Economics2001，，2： | 2 |
| 9 | Fusion neutron and ion emission from deuterium and deuterated methane cluster plasmas显示文摘 | K W Madison P K Patel D Price A Edens, M Allen, T E Cowan, J Zweiback, T Ditmire | | 0，，： | 2 |
| 10 | Strategy in emerging economies 显示文摘 | Hoskisson R E Eden L Lau C M Wright M | 2000 | Academy of Management Journal2000，43，3： | 1 |
| 11 | A systemic review of the reproductive system effects of mefformin in patients with polycystic ovary syndrome 显示文摘 | COSTELLO M F EDEN J A | 2003 | Fertil Steril2003，79，1： | 1 |
| 12 | A systemic review of the reproductive system effects of metformin in patients with polycystic ovary syndrome显示文摘 | COSTELLO M Eden JA | 2003 | Fertil Steril2003，79，： | 1 |
| 13 | An external reference to identify the internal auditory canal in middle fossa surgery 显示文摘 | Catalano PJ Eden AR | 1993 | Otolaryngol Head Neck Surg1993，108，2： | 1 |
| 14 | Examining the role of static and dynamic risk factors in the prediction of inpatient of violence显示文摘 | Barbara E McDermott John F Edens Cameron D | 2008 | Law Hum Behav2008，9，32： | 1 |
| 15 | Principles of ex ovo competitive exclusion and in ovo administration of Lactobacillus reuteri显示文摘 | EDENS F W PARKHURST C R CASAS I A | 1997 | Poultry Science1997，，76： | 1 |
| 16 | The first 1000 cases of laparoscopic radical prostatectomy in the UK: evidence of multiple 'learning curves'显示文摘 | Eden CG Neill MG Louie-Johnsun MW | 2009 | BJU Int2009，103，： | 1 |
| 17 | The E2F - regulated gene Chkl is highly expressed in triple - negative estrogen receptor - / progesterone receptor -/HER - 2 - breast carcinomas 显示文摘 | Vedinden L Bempt IV Eden G | 2007 | Cancer Res2007，67，14： | 1 |
| 18 | Ki- netic studies on the interactions of heparin and complement proteins using surface plasmon reso- nance显示文摘 | YU H MUNOZ E M EDENS R E | 2005 | Biochim Biophys Acta2005，1726，2： | 1 |
| 19 | Molecular Epidemiology of Noro- virus in Singapore, 2004-2011显示文摘 | Lim KL Eden JS Oon LL | 2013 | J Med Virol2013，85，10： | 1 |
| 20 | The photon avalanche: a new phenomenon in Pr3+-based infrared quantum counters显示文摘 | Chivian J S Case W E Eden D D | 1979 | Applied Physics Letters1979，35，2： | 1 |
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