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| 1 | Pharmaceuticals and personal care products (PPCPs) in the freshwater aquatic environment显示文摘Pharmaceuticals and personal care products(PPCPs)are a unique group of emerging environmental contaminants,due to their inherent ability to induce physiological effects in human at low doses.An increasing number of studies has confirmed the presence of various PPCPs in different environmental compartments,which raises concerns about the potential adverse effects to humans and wildlife.Therefore,this article reviews the current state-of-knowledge on PPCPs in the freshwater aquatic environment.The environmental risk posed by these contaminants is evaluated in light of the persistence,bioaccumulation and toxicity criteria.Available literature on the sources,transport and degradation of PPCPs in the aquatic environment are evaluated,followed by a comprehensive review of the reported concentrations of different PPCP groups in the freshwater aquatic environment(water,sediment and biota)of the five continents.Finally,future perspectives for research on PPCPs in the freshwater aquatic environment are discussed in light of the identified research gaps in current knowledge. | Anekwe Jennifer Ebele Mohamed Abou-Elwafa Abdallah Stuart Harrad | 2017 | Emerging Contaminants2017，3，1： | 44 |
| 2 | 植物在修复、固定和重建水生、陆生生态系统中的应用显示文摘植物能够吸收或降解污染物来修复受污染的土壤和水体[1-2],还能固定土壤、泥沙防止侵蚀和污染物从固体介质中释放[3]。众多无机和有机污染物都能被对其有耐性且生物量大的植物有效降解。例如,凤眼莲能吸收和净化来自金矿采掘废水的氰化物,这类废水含各种氰化物以及重金属元素的浓度达到导致生物体产生毒性效应的水平。检测表明氰化物对凤眼莲的半数致死剂量(LC50)为13 mg/L,将经过高浓度氰化物废水驯化后的凤眼莲放在野外小型湿地进行试验,结果显示这类植物对氰化物的降解效率更高。放射性同位素试验发现氰化物分子中的C和N原子经过植物代谢合成天冬酰胺,从而将有毒性的氰化物转化为无毒的产物[4]。尾矿场也可以用植物来修复,一方面植物可以过滤污染物浓度很高的渗滤液,另一方面栽种植物可以固定边坡减少侵蚀。将高覆盖度植被的概念应用在一个尾矿场上,通过种植北美黄杉使其全年都维持较高的蒸腾效率来减少渗滤液。而边坡的固定首先需要在坡面安置固定、菱形的新鲜柳条编织成的笼状网格,其后覆上土壤并喷播能在生长期对固定土壤发挥作用的草本、灌木以及树木种子。这项技术同样适用于河岸侵蚀防护。 | Andreas SCHAEFFER 陈忠礼 Mathias EBEL Michael EVANGELOU Henner HOLLERT Martina RO-NICKOLL Burkhard SCHMIDT 袁野 Gottfried LENNARTZ | 2012 | 重庆师范大学学报(自然科学版)2012，29，3： | 4 |
| 3 | Occurrence,seasonal variation and human exposure to pharmaceuticals and personal care products in surface water,groundwater and drinking water in Lagos State,Nigeria显示文摘The occurrence of 28 pharmaceuticals and personal care products(PPCPs)was investigated in 17 surface water samples(rivers,canals,and lagoons),12 groundwater samples(wells and boreholes,which can also be consumed for drinking)and 8 drinking water samples(bottles and sachets)during dry and rainy seasons in Lagos state,Nigeria.The most prevalent compound detected in all samples was amoxicillin(an antibiotic)at median concentrations of 1614,238 and 358 ng/L in surface water,ground water and drinking water,respectively.This is of concern due to potential impact on development of antibioticresistant microbial strains.Other frequently-detected compounds include acetaminophen,nicotine,ibuprofen,and codeine with detection frequencies of more than 70%.Investigation of seasonal variability revealed that glyburide,caffeine,naproxen and diclofenac concentrations were significantly(P<0.05)higher during the dry season(winter),while Nicotine and Codeine levels were higher during the rainy season(summer).The factors influencing such seasonal variability include:dilution by extensive rainfall,agricultural activity(for nicotine)and usage patterns of pharmaceuticals among the local community.Measured concentrations in drinking water samples were used to assess inadvertent human exposure to PPCPs in Nigerian adults.Results revealed average daily exposures of 81,14 and 3 ngƩPPCPs/kg BW/day via drinking borehole,sachet water and bottled water,respectively.While there exists no health-based limit value(HBLV)for chronic exposure to mixtures of PPCPs,our results raise concern and warrant further investigation of the potential health implications of such unintended PPCPs exposure. | Anekwe Jennifer Ebele Temilola Oluseyi Daniel S.Drage Stuart Harrad Mohamed Abou-Elwafa Abdallah | 2020 | Emerging Contaminants2020，6，1： | 4 |
| 4 | Bone turnover markers and bone density acress the menopausal transition显示文摘 | Ebeling PR Atley LM Guthrie JR | 1996 | J Clin Endocrinol Metab1996，81，： | 2 |
| 5 | Theileria parva 104 kDa microneme–rhoptry protein is membrane-anchored by a non-cleaved amino-terminal signal sequence for entry into the endoplasmic reticulum显示文摘 | Thomas Ebel Joachim Gerhards Bernd R. Binder Joachim Lipp | 1999 | Molecular & Biochemical Parasitology1999，，1： | 2 |
| 6 | Dynamic simulation and experimental validation of a two-phase closed thermosyphon for geothermal application显示文摘The heat transfer perfonmance of a vertical two-phase closed thermosyphon(TPCT)used in a geothermal heat pump was experimentally investigated.The TPCT is a verticalplain steel pipe with inner diameter of 114 mm and bored 368 m deep underground.Carbon dioxide(CO_(2))is used as working fluid.In the TPCT there is no condensation section.CO_(2)is condensed by the evaporator pf the heat pump,flows into the head of the TPCT and nuns down as a falling film along the inner wall of the pipe.For the heat transfer simulation in the TPCT,a quasi-dynamic model in which the mass transfer between the liquid and vapor phases as well as the conduction heat transfer from the surrounding soil towards the pipe is treated dynamically.However the film flow modeling is based on the Nusselt theory of frilm condenssation.The compauison of the experimental data with the numerical simulation is presented and discussed. | Johann-Christoph Ebeling Xing Luo Stephan Kabelac Sebastian Luckmann Horst Kruse | 2017 | Propulsion and Power Research2017，6，2： | 2 |
| 7 | The microbiota is dispensable for the early stages of peripheral regulatory T cell induction within mesenteric lymph nodes显示文摘Intestinal Foxp3+regulatory T cell(Treg)subsets are crucial players in tolerance to microbiota-derived and food-borne antigens,and compelling evidence suggests that the intestinal microbiota modulates their generation,functional specialization,and maintenance.Selected bacterial species and microbiota-derived metabolites,such as short-chain fatty acids(SCFAs),have been reported to promote Treg homeostasis in the intestinal lamina propria.Furthermore,gut-draining mesenteric lymph nodes(mLNs)are particularly efficient sites for the generation of peripherally induced Tregs(pTregs).Despite this knowledge,the direct role of the microbiota and their metabolites in the early stages of pTreg induction within mLNs is not fully elucidated.Here,using an adoptive transfer-based pTreg induction system,we demonstrate that neither transfer of a dysbiotic microbiota nor dietary SCFA supplementation modulated the pTreg induction capacity of mLNs.Even mice housed under germ-free(GF)conditions displayed equivalent pTreg induction within mLNs.Further molecular characterization of these de novo induced pTregs from mLNs by dissection of their transcriptomes and accessible chromatin regions revealed that the microbiota indeed has a limited impact and does not contribute to the initialization of the Treg-specific epigenetic landscape.Overall,our data suggest that the microbiota is dispensable for the early stages of pTreg induction within mLNs. | Carolin Wiechers Mangge Zou Eric Galvez Michael Beckstette Maria Ebel Till Strowig Jochen Huehn Joern Pezoldt | 2021 | Cellular & Molecular Immunology2021，18，5： | 2 |
| 8 | Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease显示文摘 | BALEMANS W PATEL N EBELING M | 2002 | J Med Genet2002，39，2： | 1 |
| 9 | Quantitative Surface Analysis by X-ray Photoelectron Spectroscopy and X-ray Exited Auger Electron Spectroscopy显示文摘 | Ebel M F Ebel H | 1990 | Mikrochim Acta[Wien]1990，11，： | 1 |
| 10 | Beta-2-glycoprotein I antibodies in patients with thrombosis 显示文摘 | Ebeling F Pettersson T Muukkonen L | 2003 | Scand J Clin Lab Invest2003，63，2： | 1 |
| 11 | Isoflurane p reconditioning myocardium against infarction via release of free radicals显示文摘 | Müllenheim J Ebel D | 2002 | Anesthesiology2002，96，： | 1 |
| 12 | Engineering analysis of the stoichiometry of photoautotrophic , autotrophic , and heterotrophic removal of ammonia-nitrogen in aquaculture systems显示文摘 | EBELING J M TIMMONS M B BISOGIN J J | 2006 | Aquaculture2006，257，： | 1 |
| 13 | Aprotinin and anaphylaxis:analysis of 12,403exposures to aprotinin in cardiac surgery显示文摘 | Dietrich W Ebell A Busley R | 2007 | Ann Thorac Surg2007，84，4： | 1 |
| 14 | Lispro Mix25 insulin as premeal therapy in type 2 diabetic patients显示文摘 | Koivisto VA Tuominen JA Ebeling P | | 0，，03： | 1 |
| 15 | Halophilic adaptation of enzymes显示文摘 | Madern D Ebel C Zaccai G | | 0，，： | 1 |
| 16 | Clinical diagnosis of pneumonia in children显示文摘 | Ebell MH | 2010 | Am Fam Phy- sician2010，82，2： | 1 |
| 17 | Lactoferrin impairs type Ⅲ secretory system function in enteropathogenie Eschericlzia coli显示文摘 | OCHOA T J MARITA N O EBEL F | 2003 | Infect Immun2003，71，9： | 1 |
| 18 | Drags from the seas-current status and microbiological implications 显示文摘 | PROSCH P EDRADA R A EBEL R | 2002 | Applied Microbiology and Biotechnology2002，59，： | 1 |
| 19 | Clinicopathogie, histologic, and'toxicologic tidings in cats inadvertently exposed to pet food contaminated with melamine and cyanuric acid显示文摘 | Cianciolo R E Bisehoff K Ebel J G | 2008 | Am Vet Med Assoc2008，233，5： | 1 |
| 20 | A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures显示文摘 | Buehbinder R Osborne RH Ebeling PR | 2009 | N Engl J Med2009，351，： | 1 |
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