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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Atom transfer radical polymerization of methyl acrylate from a multifunctional initiator at ambient temperature显示文摘 | ANNA C ROBERT V EVA M J | 2002 | Polymer2002，43，： | 1 |
| 3 | Ceramic membrane ultrafihration of anionic and nonionic surfactant solutions 显示文摘 | Eva F Benito J M Pazos C | 2005 | Journal of Membrane Science2005，246，1： | 1 |
| 4 | Effect of selected strains of Debaryomyces hansenii on the volatile compound production of dry fermented sausage 'alchichan' 显示文摘 | JESES A M JUANJ C EVA M C | 2010 | Meat Science2010，，85： | 1 |
| 5 | Contactless conductivity detection of selected organic ions in on-chip electrophoresis显示文摘 | Tanyanyiwa J Abad-Villar Eva M Hauser P C | 2004 | Electrophoresis2004，25，6： | 1 |
| 6 | Rapid determination of volatile compounds in grapes by HS-SPME coupled with GC-MS显示文摘 | Consuelo D M Soledad P C | 2005 | Talanta2005，66，5： | 1 |
| 7 | Effects of intravenous albumin in patients with cirrhosis and episodic hepatic encephalopathy: A randomized double-blind study显示文摘 | Macarena Simón-Talero Rita García-Martínez Maria Torrens Salvador Augustin Susana Gómez Gustavo Pereira Mónica Guevara Pere Ginés Germán Soriano Eva Román Jordi Sánchez-Delgado Roser Ferrer Juan C. Nieto Pilar Sunyé Inma Fuentes Rafael Esteban Juan Córdob | 2013 | Journal of Hepatology2013，，6： | 1 |
| 8 | Predominant breast-feeding from birth to six months is associated with fewer gastrointes- tinal infections and increased risk for iron de? ciency among infants显示文摘 | Eva C M Edward AF Edgar M | 2008 | The Journal of Nutrition2008，138，8： | 1 |
| 9 | Maedi-visna virus infection of ovine mammary epithelial cells显示文摘 | Rosa B Eva M Librado C | 2006 | Veterinary Research2006，37，： | 1 |
| 10 | Rapid determination of volatile compounds in grapes by HS-SPME coupled with GC-MS显示文摘 | Eva S P Consuelo D M Soledad P C | 2005 | Talanta2005，66，5： | 1 |
| 11 | A rheological study of the ageing of emulsion and microsuspension-based PVC plastisols显示文摘 | Eva G B Fernando M D Miguel C | 2008 | Journal of Applied Polymer Science2008，109，1： | 1 |
| 12 | Scintigraphic Assessment of Regionalized Defects in Myocardial Sympathetic Innervation and Blood Flow Regulation in Diabetic Patients With Autonomic Neuropathy显示文摘 | Martin J Stevens Firat Dayanikli David M Raffel Kevin C Allman Tracy Sandford Eva L Feldman Donald M Wieland James Corbett Marcus Schwaiger | 1998 | Journal of the American College of Cardiology1998，，7： | 1 |
| 13 | Separation Purification Tech显示文摘 | Chris C Chris H Eva M | 2001 | 25:1812001，25，： | 1 |
| 14 | Environmental exposure and risk assessment of fluoroquinolone antibacterial agents in wastewater and river water of the Glatt valley watershed,Switzerland显示文摘 | Eva M Golet A C Giger W | 2002 | Environ Sci Technol2002，36，17： | 1 |
| 15 | Frequency oof anovulation and early menopause among women enrolled in selected adult aids clinical trials group studies 显示文摘 | REBECCA C KATHIEEN M EVA S | 2001 | The Journal of Infections Diseases2001，15，： | 1 |
| 16 | Physiology and gene regulation of the brain NPY Y_1 receptor显示文摘 | EVA C SERRA M MELE P | 2006 | Front Neuroendocrinol2006，27，3： | 1 |
| 17 | Changes in nitrogen compounds in must and wine during fermentation and biological aging by yeasts 显示文摘 | JUAN C M EVA V | 2001 | J Agrie Food Chem2001，49，： | 1 |
| 18 | Bacterial ghosts as adjuvant particles 显示文摘 | Eva M R Jennelle M K Allan W C | 2007 | Vaccines2007，6，2： | 1 |
| 19 | Pneumatic tube delivery system for blood samples reduces turnaround times without affecting sample quality 显示文摘 | FERNANDES C M WORSTER A EVA K | 2006 | J Emerg Nuts2006，32，2： | 1 |
| 20 | M1 musicarnic receptors increase calcium current and phosphoinositide turn over in guinea-pig ventricular cardiocytes显示文摘 | Gallo M P Alloatti G Eva C | 1993 | J Physiol (Lond)1993，471，： | 1 |
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