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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | In vitro methods to study intestinal drug metabolism显示文摘 | van de Kerkhof Esther G de Graaf | 2007 | Curr Drug Metab2007，8，7： | 1 |
| 3 | Electrogram- guided substrate ablation with or without pulmonary vein isolation in patients with persistent atrial fibrillation 显示文摘 | Esther HL Hessling G Ndrepepa G | 2008 | Europace2008，10，11： | 1 |
| 4 | Vitamins C and E improve regrowth and reduce lipid peroxidation of blackberry shoot tips following cryopreservation 显示文摘 | Esther E U Scott W L Maret G T | 2010 | Plant Cell Reports2010，29，1： | 1 |
| 5 | Optimal Information Revelation in Procurement Schemes 显示文摘 | ESTHER G MORDECHAI G ANTHONY D | 2007 | Rand Journal of Econom- ics2007，38，2： | 1 |
| 6 | Is plasma 25(OH) D related to adipokines, inflammatory cytokines and insulin resistance in both a healthy and morbidly obese population?显示文摘 | Núria Vilarrasa Joan Vendrell Javier Maravall I?aki Elío Esther Solano Patricia San José Isabel García Núria Virgili Juan Soler José Manuel Gómez | 2010 | Endocrine2010，，2： | 1 |
| 7 | Acute and longterm results of solw pathway ablation in patients with atrioventricular nodal reentrant tachycardia ananalysis of the predictive factors for arrhythmia recurrence 显示文摘 | Esther HL Ndrepepa G Dong J | 2005 | PACE2005，28，： | 1 |
| 8 | Optimization of processing of fresh-cut pear显示文摘 | ESTHER A JAIME G PASCUAL L | 2008 | Journal of the Science of Food and Agricul- ture2008，88，： | 1 |
| 9 | Differential association of oral and transder?mal oestrogen replacement therapy with venous thromboem?bolism risk显示文摘 | Scarabin P Y Oger E Plu -Bureau G (for the ESTHER Study Group) | 2003 | Lancet2003，362，9382： | 1 |
| 10 | 显示文摘 | Esther L Marion G Marjan S | 2002 | Arterioscler Thromb Vasc Biol2002，22，： | 1 |
| 11 | Composition, diversity, and origin of the bacterial community in grass carp intestine显示文摘 | Wu S G Wang G T Esther R | 2012 | PLoS ONE2012，7，30： | 1 |
| 12 | Spatial variations of temperature, redox potential and contaminants in horizontal flow reed beds 显示文摘 | Joan G Esther O Enric S | 2003 | Ecological Engineering2003，21，： | 1 |
| 13 | Aging,metabolic syndrome and the heart显示文摘 | Veronica G Esther RR | 2012 | Aging Dis2012，3，3： | 1 |
| 14 | Selective dehydrolinalool hydrogenation with poly(ethylene oxide)- block -poly-2-vinylpyridine micelles filled with Pd nanoparticles显示文摘 | Natalia V Semagina Alexei V Bykov Esther M Sulman Valentina G Matveeva Stanislav N Sidorov Lidia V Dubrovina Peter M Valetsky Olga I Kiselyova Alexei R Khokhlov Barry Stein Lyudmila M Bronstein | 2003 | Journal of Molecular Catalysis A Chemical2003，，1： | 1 |
| 15 | Association between Ω3 and Ω6 fatty acid intakes and serum inflammatory markers in COPD显示文摘 | Jordi de Batlle Jaume Sauleda Eva Balcells Federico P. Gómez Michelle Méndez Esther Rodriguez Esther Barreiro Jaume J. Ferrer Isabelle Romieu Joaquim Gea Josep M. Antó Judith Garcia-Aymerich | 2012 | The Journal of Nutritional Biochemistry2012，，7： | 1 |
| 16 | Structure of the arabidopsis RPM1 gene enabling dual specificity disease resistance 显示文摘 | LAURENCE G ESTHER S | 1995 | Science1995，269，11： | 1 |
| 17 | Insertion of carbon monoxide and alkenes in palladium- carbon bonds of complexes containing rigid bidentate nitrogen ligands: the first example of isolated complexes in stepwise successive in- sertion reactions on the way to polyketones显示文摘 | Asselt R van Esther E C G Rulke R E | 1994 | J Am Chem Soc1994，116，3： | 1 |
| 18 | Fixation of sulphur dioxide by Manganese (Ⅱ)-Schiff Base complexes:thermal stability of these adducts and the possible conversion of the coordinated SO2 to sulphate显示文摘 | Marcelino Maneiro Beatriz Fernández Esther Gómez-Fórneas | 2005 | Zeitschrift Fir Anorganische and Allgemeine Chemie2005，631，11： | 1 |
| 19 | An Adaptive Color-Based Particle Filter显示文摘 | Katja N Esther K M Lue V G | 2003 | Image Vision Computing2003，21，1： | 1 |
| 20 | A possible role for secreted ferritin in tissue iron distribution显示文摘 | ESTHER G MEYRON H SHIRLY M B | 2011 | J Neural Transm2011，118，： | 1 |
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