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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Differential interactions among isolates of peanut stunt Cucumovirus and its satellite RNA显示文摘 | Vicente M Ignacio M Emilio R C | 1998 | Journal of General Virology1998，79，： | 1 |
| 3 | Maximizing upgrading and downgrading margins for ordinal regression显示文摘 | EMILIO C BELEN M B | 2011 | Mathematical Methods of Operations Research2011，74，3： | 1 |
| 4 | Phyto- plankton size structure and primary production in a highly dynamic coastal ecosystem (Riade Vigo, NW- Spain): Seasonal and short-time scale variability显示文摘 | PEDRO C EMILIO M VALESCA P | 2006 | Estuarine Coastal and Shelf Science2006，67，12： | 1 |
| 5 | Phytoplankton size structure and primary production in a highly dynamic coastal ecosystem (Ri'a de Vigo,NW-Spain):seasonal and short-time scale variability显示文摘 | Pedro C Emilio M Valesca P | 2006 | Estuarine Coastal and Shelf Science2006，67，： | 1 |
| 6 | Learning scene context for multiple object tracking显示文摘 | Emilio M Andrea C | 2009 | IEEE Transactions On hnage Process- ing2009，18，8： | 1 |
| 7 | Multispectral and LiDAR data fusion for fuel type mapping using support vector machine and decision rules 显示文摘 | GARCIA M RIANO D CHUVIECO EMILIO C SALAS J DANSON F M | 2011 | Remote Sensing of Environment2011，6，15： | 1 |
| 8 | Phenol photodegradation on platinized-TiO2 photocatalysts related to charge-carrier dynamics显示文摘 | Emilio C A Litter M I Kunst M | 2006 | Langmuir2006，22，8： | 1 |
| 9 | A simple model for estimating leaf area of hazelnut from linear measurements 显示文摘 | Valerio C Youssef R Emilio M G | 2007 | Scientia Horticulturae2007，113，： | 1 |
| 10 | Use of EIS for the evaluation of the protective properties of coatings for metallic cultural heritage : a review显示文摘 | Emilio C Diana L David M B | 2010 | Solid State Electrochem2010，14，3： | 1 |
| 11 | Latex Agglutination Assays for Detection of Non-O157 Shiga Toxin-Producing Escherichia coli Serogroups O26, O45, O103, O111,O121, and O145[dagger]显示文摘 | Medina Marjorie B Shelver Weilin L Fratamico Pina M Fortis Laurie Tillman Glenn Narang Neelam Cray William C Esteban Emilio DebRoy Chitrita | 2012 | EN2012，，5： | 1 |
| 12 | Highly stereoselective reduction of haloketones using three new yeasts: application to the synthesis of (S)-adrenergic β-blockers related to propranolol 显示文摘 | Fernando M L Jose D C Jose L B Emilio A Jose V S | 2004 | Tetrahedron: Asymmetry2004，15，： | 1 |
| 13 | A survey on bacteria inhabiting the sea surface microlayer of coastal ecosystems 显示文摘 | AGOGUEH EMILIO O C BOURRAIN M | 2005 | Microbiology Ecology2005，54，： | 1 |
| 14 | Seasonal furrow irrigation model with genetic algorithms (OPTIMEC) 显示文摘 | Pilar M Emilio C Serafin A | 2001 | Agricultural Water Manage- ment2001，52，1： | 1 |
| 15 | Pile foundation analysis and design using experimental data and3-D numerical analysis显示文摘 | EMILIOS M COMODROMOS MELLO C PAPADOPOULOU IOANNIS K RENTZEPERIS | 2009 | Journal of Geotechnical and Geoenvironmental Engineering2009，135，6： | 1 |
| 16 | Effects from diaphragm wall installation to surrounding soil and adjacent buildings 显示文摘 | EMILIOS M C MELLO C P GEORGIOS K K | 2013 | Computers and Geotechnics2013，53，： | 1 |
| 17 | Formability of similar and dissimilar friction stir welded AA 5182-H 111 and AA 6016-T4 tailored blanks 显示文摘 | LEITAO C EMILIO B CHAPARRO B M RODR/GUES D M | 2009 | Material and Design2009，30，8： | 1 |
| 18 | Pilefoundation analysis and design using experimental dataand 3-D numerical analysis显示文摘 | EMILIOS M C MELLO C P IOANNIS K R | 2009 | Computers andGeotechnics2009，36，： | 1 |
| 19 | Contrast volume during primary pereutaneous coronary intervention and subsequent contrast - induced nephropathy and mortality 显示文摘 | Giancarlo M Emilio A Jeness C | 2009 | Ann Inter Med2009，150，3： | 1 |
| 20 | Formability of Similar and Dissimilar Friction Stir Welded AA 5182--H111 and AA 6016-T4 Tailored Blanks显示文摘 | Leitao C Emilio B Chaparro B M | 2009 | Materials and Design2009，30，： | 1 |
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