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| 1 | Zn-Mg and Zn-Cu alloys for stenting applications:From nanoscale mechanical characterization to in vitro degradation and biocompatibility显示文摘In the recent decades,zinc(Zn)and its alloys have been drawing attention as promising candidates for bioresorbable cardiovascular stents due to its degradation rate more suitable than magnesium(Mg)and iron(Fe)alloys.However,its mechanical properties need to be improved in order to meet the criteria for vascular stents.This work investigates the mechanical properties,biodegradability and biocompatibility of Zn-Mg and Zn-Cu alloys in order to determine a proper alloy composition for optimal stent performance.Nanoindentation measurements are performed to characterize the mechanical properties at the nanoscale as a function of the Zn microstructure variations induced by alloying.The biodegradation mechanisms are discussed and correlated to microstructure,mechanical performance and bacterial/cell response.Addition of Mg or Cu alloying elements refined the microstructure of Zn and enhanced yield strength(YS)and ultimate tensile strength(UTS)proportional to the volume fraction of secondary phases.Zn-1Mg showed the higher YS and UTS and better performance in terms of degradation stability in Hanks’solution.Zn-Cu alloys presented an antibacterial effect for S.aureus controlled by diffusion mechanisms and by contact.Biocompatibility was dependent on the degradation rate and the nature of the corrosion products. | Claudia García-Mintegui Laura Catalina Córdoba Judit Buxadera-Palomero Andrea Marquina Emilio Jiménez-Piqué Maria-Pau Ginebra JoséLuis Cortina Marta Pegueroles | 2021 | Bioactive Materials2021，6，12： | 4 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | Computerized physician order entry‐based system to prevent HBV reactivation in patients treated with biologic agents: The PRESCRIB project显示文摘 | Blanca Sampedro Cándido Hernández‐López José Ramón Ferrandiz Aitziber Illaro Emilio Fábrega Antonio Cuadrado Paula Iruzubieta Susana Menéndez Joaquín Cabezas Javier Crespo | 2014 | Hepatology2014，，1： | 2 |
| 4 | Satellite remote sensing analysis to monitor desertification proeesses in the crop-rangeland boundary of Argentina 显示文摘 | ALRFEDO D C EMILIO C | 2002 | Journal of Arid Environments2002，52，： | 1 |
| 5 | Differential interactions among isolates of peanut stunt Cucumovirus and its satellite RNA显示文摘 | Vicente M Ignacio M Emilio R C | 1998 | Journal of General Virology1998，79，： | 1 |
| 6 | Satellite remote sensing analysis to monitor desertifieation processes in the crop-rangeland boundary of Argentina显示文摘 | Alfredo D C Emilio C Ana C | 2002 | Journal of Arid Environments2002，52，： | 1 |
| 7 | Unexpected healing of cutaneous ulcers in a short child显示文摘 | Rolando C Roberto R Emilio F | 2001 | Lancet2001，358，： | 1 |
| 8 | Maximizing upgrading and downgrading margins for ordinal regression显示文摘 | EMILIO C BELEN M B | 2011 | Mathematical Methods of Operations Research2011，74，3： | 1 |
| 9 | Phyto- plankton size structure and primary production in a highly dynamic coastal ecosystem (Riade Vigo, NW- Spain): Seasonal and short-time scale variability显示文摘 | PEDRO C EMILIO M VALESCA P | 2006 | Estuarine Coastal and Shelf Science2006，67，12： | 1 |
| 10 | Phytoplankton size structure and primary production in a highly dynamic coastal ecosystem (Ri'a de Vigo,NW-Spain):seasonal and short-time scale variability显示文摘 | Pedro C Emilio M Valesca P | 2006 | Estuarine Coastal and Shelf Science2006，67，： | 1 |
| 11 | On Minimax regret Huff Location Models显示文摘 | LENYS B RAFAEL B EMILIO C | 2011 | Computers & Op erations Research2011，38，1： | 1 |
| 12 | Learning scene context for multiple object tracking显示文摘 | Emilio M Andrea C | 2009 | IEEE Transactions On hnage Process- ing2009，18，8： | 1 |
| 13 | Characterization of Focal Liver Lesions with Contrast-specific US Modes and a Sulfur Hexafluoride-filled Microbubble Contrast Agent:Diagnostic Performance and Confidence显示文摘 | Emilio Q Fabrizio C Michele B et al | 2004 | Radiology2004，232，4： | 1 |
| 14 | Effect of electromagnetic fields on bone mineral density and biochemical markers of bone turnover in osteoporosis 显示文摘 | Nicola C Emilio B Simone C | 2001 | Radiat Environ Biophys2001，62，3： | 1 |
| 15 | Multispectral and LiDAR data fusion for fuel type mapping using support vector machine and decision rules 显示文摘 | GARCIA M RIANO D CHUVIECO EMILIO C SALAS J DANSON F M | 2011 | Remote Sensing of Environment2011，6，15： | 1 |
| 16 | Satellite Remote Sensing Analysis to Monit- or Desertification Processes in the Crop-rangeland Boundary of Argentina显示文摘 | Alfredo D C Emilio C Camarasaw A | 2002 | Journal of Arid Environments2002，52，： | 1 |
| 17 | Effects of HR AS oncogene on cell cycle progression in a cervical cancer-derived cell line显示文摘 | Emilio CA Federico C Jorge RE | 2005 | Archives of Medical Research2005，36，4： | 1 |
| 18 | Satellite remote sensing analysis to monitor desertification processes in the crop-range- Iand boundary of Argentina显示文摘 | Alfredo D C Emilio C Camarasa A | 2002 | Journal of Arid Environment2002，52，1： | 1 |
| 19 | Phenol photodegradation on platinized-TiO2 photocatalysts related to charge-carrier dynamics显示文摘 | Emilio C A Litter M I Kunst M | 2006 | Langmuir2006，22，8： | 1 |
| 20 | A simple model for estimating leaf area of hazelnut from linear measurements 显示文摘 | Valerio C Youssef R Emilio M G | 2007 | Scientia Horticulturae2007，113，： | 1 |
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