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	题名	作者	年代	出处	被引量
1	Extending the functions of the homeotic transcription factor Cdx2 in the digestive system through nontranscriptional activities显示文摘The homeoprotein encoded by the intestinal-specific Cdx2 gene is a major regulator of gut development and homeostasis,also involved in colon cancer as well as in intestinal-type metaplasias when it is abnormally expressed outside the gut.At the molecular level,structure/function studies have demonstrated that the Cdx2 protein is a transcription factor containing a conserved homeotic DNA-binding domain made ofthree alpha helixes arranged in a helix-turn-helix motif,preceded by a transcriptional domain and followed by a regulatory domain.The protein interacts with several thousand sites on the chromatin and widely regulates intestinal functions in stem/progenitor cells as well as in mature differentiated cells.Yet,this transcription factor also acts trough original nontranscriptional mechanisms.Indeed,the identification of novel protein partners of Cdx2 and also of a splicing variant revealed unexpected functions in the control of signaling pathways like the Wnt and NF-k B pathways,in double-strand break DNA repair and in premessenger RNA splicing.These novel functions of Cdx2 must be considered to fully understand the complexity of the role of Cdx2 in the healthy intestine and in diseases.	Jean-Noel Freund Isabelle Duluc Jean-Marie Reimund Isabelle Gross Claire Domon-Dell	2015	World Journal of Gastroenterology2015，21，5：	5
2	Cdx2 Controls Expression of the Protocadherin Mucdhl, an Inhibitor of Growth and β-Catenin Activity in Colon Cancer Cells显示文摘	Isabelle Hinkel Isabelle Duluc Elisabeth Martin Dominique Guenot Jean–Noel Freund Isabelle Gross	2012	Gastroenterology2012，，4：	2
3	Changing intestinal connective tissue interactions alters homeobox gene expression in epithelial cells显示文摘	Duluc I Lorentz O Fritsch C	1997	J Cell Sci1997，110，：	1
4	Completely laparoscopic totaland partial gastrectomy for benign and malignant diseases:a single insti-tute's prospective analysis显示文摘	Dulucs JL Wintringer P Perissat J	2005	J Am Coll Surg2005，200，2：	1
5	The intestine-specific homeobox gene Cdx2 decreases mobility and antagonizes dissemination of colon cancer ceils 显示文摘	Gross I Duluc I Benameur T	2005	Oncogene2005，27，1：	1
6	The intestine-specific ho- meobox gene Cdx2 decreases mobility and antagonizes dissemina- tion of colon cancer cells 显示文摘	Gross I Duluc I Benameur T	2008	Oncagene2008，27，1：	1
7	Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells 显示文摘	Duluc D Delneste Y Tan F	2007	Blood2007，110，13：	1
8	The Cdx2 homeabox gene has a tumour suppressor function in the distal colon in addi- tion to a homeotie role during gut development显示文摘	Bonhomme C Duluc I Martin E	2003	Gut2003，52，10：	1
9	Somatostatin ana- logs: does pharmacology impact antitumor efficacy? 显示文摘	CHALABI M DULUC C CARON P	2014	Trends Endocrinol Metab2014，25，3：	1
10	The intestine-specific homeobox gene Cdx2 decreases mobility and antagonizes dissemination of colon cancer cells 显示文摘	Gross I Duluc I Benameur T	2008	Oncogene2008，27，1：	1
11	Tumor-associated leu-kemia inhibitory factor and IL-6 skew monocyte differentia-tion into tumor-associated macrophage-like cells显示文摘	Duluc D Delneste Y Tan F	2007	Blood2007，110，13：	1
12	Dowrtregulation of the colon tumour-suppressor homeobox gene Cdx-2 by oncogenic ms 显示文摘	Lorentz O Cadoret A Duluc I	1999	Oncogene1999，18，1：	1
13	The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development显示文摘	BONHOMME C DULUC I MARTIN E	2003	Gut2003，52，10：	1
14	Propionyl-L-carnitine corrects meetabolic and Cardiovascular alterations in diet-induced obese mice and improves liver respiratory chain Activity显示文摘	Mingorance C Duluc L Chalopin M		0，，03：	1
15	Systems biology of antioxidants显示文摘	ANDRIANTSITOHAINA R DULUC L GARCIA-RODRIGUEZ J C	2012	Clinical science2012，123，3：	1
16	Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells显示文摘	Duluc D Delneste Y Tan F Moles M P Grimaud L Lenoir J Preisser L Anegon I Catala L Ifrah N Descamps P Gamelin E Gascan H Hebbar M Jeannin P		0，，13：	1
17	Loss of Somatostatin Receptor Subtype 2 Promotes Growth of KRAS-Induced Pancreatic Tumors in Mice by Activating PI3K Signaling and Overexpression of CXCL16 显示文摘	Chalabi-Dchar M Cassant-Sourdy S Duluc C	2015	Gastroenterology2015，148，7：	1
18	Key elements of the BMP/Smad pathway co-localize with CDX2 in intestinal metaplasia and regu?late CDX2 expression in humangastric cell lines显示文摘	Barros R Pereira B Duluc I	2008	J Pathol2008，215，4：	1
19	Systems biology of antioxidants显示文摘	Andriantsitohaina R Duluc L	2012	Clin Sei2012，123，：	1
20	The intestine specific homeobox gene Cdx2 decreases mobility and antagonizes dissemination of colon cancercells显示文摘	Gross I Duluc I Benameur T	2008	Oncogene2008，27，1：	1

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