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| 1 | Leptin and its actions on reproduction in males显示文摘Leptin, an adipocyte-derived hormone, serves numerous physiological functions in the body, particularly during puberty and reproduction. The exact mechanism by which leptin activates the gonadotropin-releasing hormone (GnRH) neurons to trigger puberty and reproduction remains unclear. Given the widespread distribution of leptin receptors in the body, both central and peripheral mechanisms involving the hypothalamic-pituitary-gonadal axis have been hypothesized. Leptin is necessary for normal reproductive function, but when present in excess, it can have detrimental effects on the male reproductive system. Human and animal studies point to leptin as a link between infertility and obesity, a suggestion that is corroborated by findings of low sperm count, increased sperm abnormalities, oxidative stress, and increased leptin levels in obese men. In addition, daily leptin administration to normal-weight rats has been shown to result in similar abnormalities in sperm parameters. The major pathways causing these abnormalities remain unidentified;however, these adverse effects have been attributed to leptin-induced increased oxidative stress because they are prevented by concurrently administering melatonin. Studies on leptin and its impact on sperm function are highly relevant in understanding and managing male infertility, particularly in overweight and obese men. | Ifrah Alam Malik Damayanthi Durairajanayagam Harbindar Jeet Singh | 2019 | Asian Journal of Andrology2019，21，3： | 2 |
| 2 | Single cell analy - sis of phosphoinositide 3 - kinase / Akt and ERK aetivationin acute my- eloid leukemia by flow eytometry显示文摘 | Bardet V Tamburini J Ifrah N | 2006 | Haema- tologiea2006，91，6： | 1 |
| 3 | On the effect of La-Cr-O-phase composition on diesel soot catalytic com?bustion显示文摘 | Ifrah S Kaddouri A Gelin P | 2007 | Catalysis Communications2007，8，： | 1 |
| 4 | Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells显示文摘 | Duluc D Delneste Y Tan F Moles M P Grimaud L Lenoir J Preisser L Anegon I Catala L Ifrah N Descamps P Gamelin E Gascan H Hebbar M Jeannin P | | 0，，13： | 1 |
| 5 | Single cell analysis of phosphoinositide 3-kinase/Akt and ERK activation in acute myeloid leukemia by flow cytometry显示文摘 | Bardet V Tamburini J Ifrah N | | 0，，06： | 1 |
| 6 | Intensive therapies in follicular non-Hodgkin lymphomas显示文摘 | Hunault-Berger M Ifrah N Solal-Celigny P | 2002 | Blood2002，100，4： | 1 |
| 7 | New indolicidin analogues with potent antibacterial activity显示文摘 | Ryge T S Doisy X Ifrah D | 2004 | Journal of Peptide Research2004，64，5： | 1 |
| 8 | The rarely reported tet (31) tetracycline resistance determinant is common in Gallibacterium anatis 显示文摘 | Bojesen A M Bager R J Ifrah D | 2011 | Vet Microbiol2011，149，34： | 1 |
| 9 | Single cell analysis of phosphoinosilide 3-kinase/Akt and ERK activation in acute myeloid leukemia by flow cytometry 显示文摘 | Bardet V Tamhurini J Ifrah N | 2006 | Haematologica2006，91，6： | 1 |
| 10 | On the effect of La-Cr-O- phase composition on diesel soot catalytic combustion 显示文摘 | Ifrah S Kaddouri A Gelin P | 2007 | Catalysis Commtmications2007，，8： | 1 |
| 11 | Single cell analysis of phos- pholnasitide 3 - kinase/Akt and ERK activation in acute myeioid leu- kemia by flow cytometry 显示文摘 | Bardet V Tamburini J Ifrah N | 2006 | Haematologica2006，91，6： | 1 |
| 12 | Spontaneous remission in adult acute Ieukernia显示文摘 | Ifrah N James 1M Viguie F | 1985 | Cancer1985，56，5： | 1 |
| 13 | The antimicrobial lysine-peptoid hybrid LP5 inhibits DNA replication and induces the SOS response in Staphylococcus aureus显示文摘 | Gottschalk S Ifrah D Lerche S | 2013 | BMCMicrobiol2013，，： | 1 |
| 14 | The rarely reported tet (31) tetracycline resistance deter- minant is common in Gallibacterium anatis 显示文摘 | BOJESEN A M BAGER R J IFRAH D | 2011 | Vet Microbiol2011，149，34： | 1 |
| 15 | The rarely reported tet (31) tetracycline resistance determinant is common in Gallibacterium anatis显示文摘 | Anders M. Bojesen Ragnhild J. Bager Dan Ifrah Frank M. Aarestrup | 2010 | Veterinary Microbiology2010，，3： | 1 |
| 16 | Antimicrobial susceptibility and tetracycline resistance determinant genotyping of Gallibacterium anatis显示文摘 | Anders M. Bojesen Maria E. Vazquez Ragnhild J. Bager Dan Ifrah Carlos Gonzalez Frank M. Aarestrup | 2010 | Veterinary Microbiology2010，，1： | 1 |
| 17 | Increased risk of secondary acute nonlymphocytic leukemia after extended-field radiation therapy combined with MOPP chemotherapy of Hodgkin' s disease显示文摘 | Ifrah N Payen C | 1990 | J Clin Oncol1990，8，7： | 1 |
| 18 | Single cell analysis of phos- phoinositide 3-kinase/Akt and ERK activation in acute myeloid leukemia by flow cytometry 显示文摘 | Bardet V Tamburlni J Ifrah N | 2006 | Haemmologiea2006，91，6： | 1 |
| 19 | Bone marrow transplanta- tion for adult poor prognosis lymphoblastic lymphoma in first complete remission显示文摘 | Milpied N Ifrah N Kuentz M | 1989 | Br J Haematol1989，73，1： | 1 |
| 20 | You be the judge the success of fffteeu years of sentencing under Unite States Sentencing Guidelines 显示文摘 | Kirbr D behre A Jeff Ifrah | 2003 | American Criminal Law Review2003，40，： | 1 |
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