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| 1 | Exogenous plant MIR168a specifically targets mammalian LDLRAPI: evidence of cross-kingdom regulation by microRNA显示文摘 | Lin Zhang Dongxia Hou Xi Chen Donghai Li Lingyun Zhu Yuj ing Zhang Jing Li Zhen Bian Xiangying Liang Xing Cai Yuan Yin Cheng Wang Tianfu Zhang Dihan Zhu Dianmu Zhang Jie Xu Qun Chen Yi Ba Jing Liu Qiang Wang Jianqun Chen Jin Wang Meng Wang Qipeng Zhang Junfeng Zhang Ke Zen Chen-Yu Zhang | 2012 | Cell Research2012，22，1： | 155 |
| 2 | Honeysuckle-encoded atypical microRNA2911 directly Largets influenza A viruses显示文摘 | Zhen Zhou Xihan Li Jinxiong Liu Lei Dong Qun Chen Jialing Liu Huihui Kongt Qianyi Zhang Xian Qi Dongxia Hou Lin Zhang Guoquan Zhang Yuchen Liu Yujing Zhang Jing Li Jin Wang Xi Chen Hua Wang Junfeng Zhang Hualan Chen Ke Zen Chen-Yu Zhang | 2015 | Cell Research2015，25，1： | 104 |
| 3 | Review on the Research and Practice of Deep Learning and Reinforcement Learning in Smart Grids显示文摘Smart grids are the developmental trend of power systems and they have attracted much attention all over the world.Due to their complexities,and the uncertainty of the smart grid and high volume of information being collected,artificial intelligence techniques represent some of the enabling technologies for its future development and success.Owing to the decreasing cost of computing power,the profusion of data,and better algorithms,AI has entered into its new develop-mental stage and AI 2.0 is developing rapidly.Deep learning(DL),reinforcement learning(RL)and their combination-deep reinforcement learning(DRL)are representative methods and relatively mature methods in the family of AI 2.0.This article introduces the concept and status quo of the above three methods,summarizes their potential for application in smart grids,and provides an overview of the research work on their application in smart grids. | Dongxia Zhang Xiaoqing Han Chunyu Deng | 2018 | CSEE Journal of Power and Energy Systems2018，4，3： | 44 |
| 4 | 老年痴呆患者家庭照护者负担及其应对策略显示文摘老年痴呆主要包括阿尔茨海默病和血管性痴呆,患者表现为认知功能损害和精神行为症状,最终生活无法自理,不仅严重影响患者的生活质量,也给家庭和社会带来沉重的负担〔1〕。由于照护的性质,如照护者需要24 h不间断地看护痴呆症老人以及在应对痴呆症老人精神和行为症状过程中的困难,照护居家痴呆症老人被公认为是一项极具挑战性的工作〔2,3〕。各种并发症如尿失禁、压力性溃疡、跌倒及营养不良所致的髋关节骨折等进一步加重了痴呆老人的照护需求。据文献报道,高达50%的老年人有一种或者一种以上的慢性疾病,需要长期的综合性照护〔4,5〕。在中国,照顾老人被看成是一个家庭的责任,加之我国目前医疗服务条件及保障体系的问题,家庭成为痴呆老人最重要的照顾支持来源,家庭照护者扮演着十分重要的角色。本文旨在对老年痴呆家庭照护者负担及其应对策略进行综述。 | 王婧 Lily Dongxia Xiao 王瑶 何国平 | 2014 | 中国老年学杂志2014，34，8： | 35 |
| 5 | Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth显示文摘 | Yuan Yin Xing Cai Xi Chen Hongwei Liang Yujing Zhang Jing Li Zuoyun Wang Xiulan Chen Wen Zhang Seiji Yokoyama Cheng Wang Liang Li Limin Li Dongxia Hou Lei Dong Tao Xu Takachika Hiroi Fuquan Yang Hongbin Ji Junfeng Zhang Ke Zen Chen-Yu Zhang | 2014 | Cell Research2014，24，10： | 33 |
| 6 | Deep Reinforcement Learning for Power System Applications: An Overview显示文摘Due to increasing complexity, uncertainty and data dimensions in power systems, conventional methods often meet bottlenecks when attempting to solve decision and control prob- lems. Therefore, data-driven methods toward solving such prob- lems are being extensively studied. Deep reinforcement learning (DRL) is one of these data-driven methods and is regarded as real artificial intelligence (AI). DRL is a combination of deep learning (DL) and reinforcement learning (RL). This field of research has been applied to solve a wide range of complex sequential decision-making problems, including those in power systems. This paper firstly reviews the basic ideas, models, algorithms and techniques of DRL. Applications in power systems such as energy management, demand response, electricity market, operational control, and others are then considered. In addition, recent advances in DRL including the combination of RL with other classical methods, and the prospect and challenges of applications in power systems are also discussed. | Zidong Zhang Dongxia Zhang Robert C.Qiu | 2020 | CSEE Journal of Power and Energy Systems2020，6，1： | 32 |
| 7 | Expression and significance of PTEN, hypoxia-inducible factor-1 alpha in colorectal adenoma and adenocarcinoma显示文摘AIM: To investigate the expression and significance of PTEN,hypoxia-inducible factor-1 alpha (HIF-1α), and targeting gene VEGF during colorectal carciogenesis.METHODS: Total 71 cases colorectal neoplasms (9 cases of colorectal adenoma and 62 colorectal adenocarcinoma)were formalin fixed and paraffin-embedded, and all specimens were evaluated for PTEN mRNA, HIF-1α mRNA and VEGF protein expression. PTEN mRNA, HIF-1α mRNA were detected by in situ hybridization. VEGF protein was identified by citrate-microwave SP immunohistochemical method.RESULTS: There were significant differences in PTEN, HIF1α and VEGF expression between colorectal adenomas and colorectal adenocarcinoma (P<0.05). The level of PTEN expression decreased as the pathologic stage increased.Conversely, HIF-1α and VEGF expression increased with the Dukes stage as follows: stage A (0.1029±0.0457:0.1207± 0.0436), stage B (0.1656±0.0329: 0.1572±0.0514),and stage C+D (0.2335±0.0748: 0.2219±0.0803). For PTEN expression, there was a significant difference among Dukes stage A, B, and C+D, and the level of PTEN expression was found to be significant higher in Dukes stage A or B than that of Dukes stage C or D. For HIF-1α expression,there was a significant difference between Dukes stage A and B, and the level of HIF-1α expression was found to be significantly higher in Dukes stage C+D than that of Dukes stage A or B. The VEGF expression had similar results as HIF-1α expression. In colorectal adenocarcinoma,decreased levels of PTEN were significantly associated with increased expression of HIF-1α mRNA (r=-0.36, P<0.05)and VEGF protein (r=-0.48, P<0.05) respectively. The levels of HIF-1 were positively correlated with VEGF expression (r=0.71, P<0.01).CONCLUSION: Loss of PTEN expression and increased levels of HIF-1α and VEGF may play an important role in carcinogenesis and progression of colorectal adenocarcinoma. | Ying-AnJiang Li-FangFan Chong-QingJiang You-YuanZhang He-ShengLuo Zhi-JiaoTang DongXia MingWang | 2003 | World Journal of Gastroenterology2003，9，3： | 33 |
| 8 | Mouse miRNA-709 directly regulates miRNA-15a/16-1 biogenesis at the posttranscriptional level in the nucleus: evidence for a microRNA hierarchy system显示文摘MicroRNAs (miRNAs ) 是内长的 noncoding RNA (~ 22 nt ) 在细胞质在 post-transcriptional 水平调整目标基因表示。在房间原子核的要求功能的 argonaute 家庭蛋白质提示了我们假设那 miRNAs 的 miRNAs 和 miRNA 的存在的最近的发现可以也在房间原子核有规章的功能。在这研究,我们证明老鼠 miR-709 主要位于各种各样的房间类型的原子核并且它的原子本地化模式很快在 apoptotic 刺激之上变化。在房间原子核, miR-709 直接在 pri-miR-15a/16-1 上绑在一个 19-nt miR-709 识别元素并且阻止它处理成 pre-miR-15a/16-1,导致 miR-15a/16-1 成熟的抑制。而且,原子 miR-709 通过 miR-15a/16-1 小径参予房间 apoptosis 的规定。在摘要,现在的学习提供一 miRNA 能由直接在原子核指向他们的主要抄本控制另外的 miRNAs 的生物的续生说的第一条证据。 | Rui Tang Limin Li Dihan Zhu Dongxia Hou Ting Cao Hongwei Gu Jing Zhang Junyuan Chen Chen-Yu Zhang Ke Zen | 2012 | Cell Research2012，22，3： | 23 |
| 9 | 发展性案例讨论法在中国老年护理继续教育中的应用显示文摘20世纪90年代,老年护理学才陆续被我国多所护理高等院校列为必修课程。这就造成大多数护士缺乏系统的老年护理知识,因此,举办各种类型的老年护理继续教育,提高护士老年护理知识和技能尤为重要。国家卫生部于1997年颁发了《继续护理教育暂行规定》和《继续护理学教育学历授予试行办法》,对继续护理学教育的对象、 | Xiao Lily Dongxia 沈军 刘慧 | 2012 | 中国老年学杂志2012，32，23： | 22 |
| 10 | An Accurate and Real-time Method of Self-blast Glass Insulator Location Based on Faster R-CNN and U-net with Aerial Images显示文摘This paper proposes a new deep learning framework for the location of broken insulators(in particular the self-blast glass insulator)in aerial images.We address the broken insulators location problem in a low signal-noise-ratio(SNR)setting.We deal with two modules:1)object detection based on Faster R-CNN,and 2)classification of pixels based on U-net.For the first time,our paper combines the above two modules.This combination is motivated as follows:Faster R-CNN is used to improve SNR,while the U-net is used for classification of pixels.A diverse aerial image set measured by a power grid in China is tested to validate the proposed approach.Furthermore,a comparison is made among different methods and the result shows that our approach is accurate in real time. | Zenan Ling Dongxia Zhang Robert C.Qiu Zhijian Jin Yuhang Zhang Xing He Haichun Liu | 2019 | CSEE Journal of Power and Energy Systems2019，5，4： | 22 |
| 11 | 社区痴呆症病人家庭照顾者负担及影响因素研究显示文摘[目的]探讨痴呆症病人家庭照顾者负担及其影响因素。[方法]采用多点横断面研究设计,应用一般资料量表、照顾者负担问卷(CBI)、中文版神经精神科问卷知情者版(NPI-Q)和社会支持量表(SSRS)对152例社区痴呆症病人主要家庭照顾者进行测评,分析影响家庭照顾者负担的因素。[结果]152例主要家庭照顾者每周花费在照顾痴呆症病人的时间平均为127.60h,超过半数(55.3%)的照顾者因为照顾痴呆症病人而承受经济压力;主观照顾负担得分38.89分±12.94分;多元逐步回归分析结果显示,影响照顾者主观负担的因素包括病人痴呆症精神行为症状严重程度、是否与病人同住、家中分担照顾任务的人数、寻求情感支持行为以及照顾者健康状况(P<0.05)。[结论]我国痴呆症病人家庭照顾者负担明显高于其他国家或地区同类人群的研究报道,病人痴呆症精神行为症状严重程度、是否与病人同住、家中分担照顾任务的人数、寻求情感支持行为以及照顾者健康状况影响照顾者的主观负担。 | 王婧 Lily Dongxia Xiao 李小妹 | 2016 | 护理研究(上旬版)2016，30，3： | 20 |
| 12 | Charge Structure of a Summer Thunderstorm in North China:Simulation Using a Regional Atmospheric Model System显示文摘Electrification and simple discharge schemes are coupled into a 3D Regional Atmospheric Model System(RAMS) as microphysical parameterizations, in accordance with electrical experiment results. The dynamics, microphysics, and electrification components are fully integrated into the RAMS model, and the inductive and non-inductive electrification mechanisms are considered in the charging process. The results indicate that the thunderstorm mainly had a normal tripole charge structure.The simulated charge structure and lightning frequency are basically consistent with observations of the lightning radiation source distribution. The non-inductive charging mechanism contributed to the electrification during the whole lifetime of the thunderstorm, while the inductive electrification mechanism played a significant role in the development period and the mature stage when the electric field reached a large value. The charge structure in the convective region and the rearward region are analyzed, showing that the charge density in the convective region was double that in the rearward region. | LIU Dongxia QIE Xiushu PENG Liang LI Wanli | 2014 | Advances in Atmospheric Sciences2014，31，5： | 16 |
| 13 | Effects of dietary fiber on human health显示文摘Dietary fiber(DF)is believed to provide important health benefits and it has become a research hotspot.DF exists in most natural foods,including fruits(16.74%-91.24%),vegetables(6.53%-85.19%),grains(9.76%-69.20%)and so on.DF has different physicochemical properties such as water holding capacity(WHC)(2.01-25.03 g/g),water swelling capacity(WSC)(0.95-23.90 mL/g),oil holding capacity(OHC)(0.65-29.00 g/g),glucose adsorption capacity(GAC)(0.17-4.65 mmol/g),cholesterol adsorption capacity(CAC)(0.03-37.10 mg/g)and viscosity,which make it exhibits different physiological functions such as reducing the risk of obesity,diabetes,cancer,and intestinal diseases.On the basis of consulting related databases,the physicochemical properties of DF and its derived physiological functions are reviewed.It is found that DF has effect on the prevention and treatment of obesity due to good WHC,WSC,OHC and CAC.Good GAC can relieve the symptoms of diabetes.The physicochemical properties of WHC and WSC can reduce the risk of cancer.The WHC,WSC and viscosity are beneficial to intestinal health. | Yang He Bixiang Wang Liankui Wen Fengzhong Wang Hansong Yu Dongxia Chen Xin Su Chi Zhang | 2022 | Food Science and Human Wellness2022，11，1： | 15 |
| 14 | 居家痴呆症病人精神行为症状及相关因素的研究显示文摘[目的]探讨居家痴呆症病人精神行为症状及其相关因素。[方法]采用多点横断面研究设计,应用一般资料问卷、神经精神科问卷知情者版、社会支持评定量表和照顾者负担量表对152例居家痴呆症病人及其主要家庭照顾者进行测评,分析痴呆症精神行为症状的发生情况,探讨其影响因素及其对照顾者负担的影响。[结果]本组高达98.7%的痴呆症病人存在一种或多种精神行为症状,病人痴呆症病程及自理情况对精神行为症状严重性有影响(P<0.05);最常见的精神行为症状为情感淡漠/漠不关心、抑郁/心境恶劣、夜间行为与睡眠障碍、焦虑以及食欲/进食异常;社会支持3个维度中,客观支持对精神行为症状的影响大;精神行为症状对照顾者生理性负担的影响最大。[结论]我国居家痴呆症病人精神行为症状及各单项症状的患病率均较高,提示精神行为症状管理与干预措施的制定应针对病人具有挑战性的行为,基于研究证据,依托于社区,同时适合我国国情、符合我国传统文化,这样才可能有较好的有效性、可及性和推广性。 | 王婧 Lily Dongxia Xiao 罗艳 李小妹 | 2018 | 护理研究2018，32，9： | 14 |
| 15 | 痴呆症病人家庭照顾者社会支持及相关因素研究显示文摘[目的]探讨居家痴呆症病人家庭照顾者社会支持及其相关因素。[方法]采用多点横断面研究设计,应用一般资料问卷、社会支持评定量表和照顾者负担量表对152位痴呆症病人的家庭照顾者进行测评,分析照顾者社会支持情况,探讨其相关因素及其对照顾者负担的影响。[结果]本组研究对象社会支持得分为(32.26±5.51)分,显著低于我国常模(t=-5.158,P=0.000);单因素分析显示配偶照顾者、不在业的照顾者、教育程度较低的照顾者以及与病人同住的照顾者社会支持总分或分维度得分较低(P<0.05),且照顾者年龄及每周照顾时间与社会支持总分或分维度得分呈负相关(P<0.05);除生理性负担和情感性负担两个维度外,照顾者负担总分及其他维度得分与不同维度的社会支持得分呈负相关(P<0.05)。[结论]本组居家痴呆症病人家庭照顾者社会支持情况不容乐观,针对社会支持的弱势群体、构建符合照顾者需求与特点的支持性干预措施意义重大,以期改善照顾者身心状况与照顾质量,提高照顾者与痴呆症病人双方的生活质量。 | 王婧 罗艳 Lily Dongxia Xiao 李小妹 | 2019 | 护理研究2019，33，14： | 14 |
| 16 | Laser performance of the SG-Ⅲ laser facility显示文摘SG-Ⅲ laser facility is now the largest laser driver for inertial confinement fusion research in China. The whole laser facility can deliver 180 kJ energy and 60 TW power ultraviolet laser onto target, with power balance better than 10%.We review the laser system and introduce the SG-Ⅲ laser performance here. | Wanguo Zheng Xiaofeng Wei Qihua Zhu Feng Jing Dongxia Hu Jingqin Su Kuixing Zheng Xiaodong Yuan Hai Zhou Wanjun Dai Wei Zhou Fang Wang Dangpeng Xu Xudong Xie Bin Feng Zhitao Peng Liangfu Guo Yuanbin Chen Xiongjun Zhang Lanqin Liu Donghui Lin Zhao Dang Yong Xiang Xuewei Deng | 2016 | High Power Laser Science and Engineering2016，4，3： | 13 |
| 17 | Accurate Evaluation of Free-form Surface Profile Error Based on Quasi Particle Swarm Optimization Algorithm and Surface Subdivision显示文摘Although significant progress has been made in precision machining of free-form surfaces recently, inspection of such surfaces remains a difficult problem. In order to solve the problem that no specific standards for the verification of free-form surface profile are available, the profile parameters of free-form surface are proposed by referring to ISO standards regarding form tolerances and considering its complexity and non-rotational symmetry. Non-uniform rational basis spline(NURBS) for describing free-form surface is formulated. Crucial issues in surface inspection and profile error verification are localization between the design coordinate system(DCS) and measurement coordinate system(MCS) for searching the closest points on the design model corresponding to measured points. A quasi particle swarm optimization(QPSO) is proposed to search the transformation parameters to implement localization between DCS and MCS. Surface subdivide method which does the searching in a recursively reduced range of the parameters u and v of the NURBS design model is developed to find the closest points. In order to verify the effectiveness of the proposed methods, the design model is generated by NURBS and the measurement data of simulation example are generated by transforming the design model to arbitrary position and orientation, and the parts are machined based on the design model and are measured on CMM. The profile errors of simulation example and actual parts are calculated by the proposed method. The results verify that the evaluation precision of freeform surface profile error by the proposed method is higher 10%-22% than that by CMM software. The proposed method deals with the hard problem that it has a lower precision in profile error evaluation of free-form surface. | WEN Xiulan ZHAO Yibing WANG Dongxia ZHU Xiaochun XUE Xiaoqiang | 2013 | Chinese Journal of Mechanical Engineering2013，26，2： | 13 |
| 18 | Laser performance upgrade for precise ICF experiment in SG-Ⅲ laser facility显示文摘The SG-Ⅲlaser facility(SG-Ⅲ)is the largest laser driver for inertial confinement fusion(ICF)researches in China,which has 48 beamlines and can deliver 180 kJ ultraviolet laser energy in 3 ns.In order to meet the requirements of precise physics experiments,some new functionalities need to be added to SG-Ⅲand some intrinsic laser performances need upgrade.So at the end of SG-Ⅲ's engineering construction,the 2-year laser performance upgrade project started.This paper will introduce the newly added functionalities and the latest laser performance of SG-Ⅲ.With these function extensions and performance upgrade,SG-Ⅲis now fully prepared for precise ICF experiments and solidly paves the way towards fusion ignition. | Wanguo Zheng Xiaofeng Wei Qihua Zhu Feng Jing Dongxia Hu Xiaodong Yuan Wanjun Dai Wei Zhou Fang Wang Dangpeng Xu Xudong Xie Bin Feng Zhitao Peng Liangfu Guo Yuanbin Chen Xiongjun Zhang Lanqin Liu Donghui Lin Zhao Dang Yong Xiang Rui Zhang Fang Wang Huaiting Jia Xuewei Deng | 2017 | Matter and Radiation at Extremes2017，2，5： | 13 |
| 19 | Catalyst-Free Growth of Nanographene Films on Various Substrates显示文摘我们开发了一个新方法在各种各样的底层上直接种一致 graphene 电影,例如绝缘体,半导体,甚至金属,没有使用任何催化剂。生长用遥远的血浆改进化学药品蒸汽免职(r-PECVD ) 被执行在相对低的温度的系统,启用 graphene 电影的免职直到 4 英寸的晶片规模。扫描通道显微镜学(STM ) 证实电影由在侧面的尺寸的十纳米的 nanocrystalline graphene 粒子组成。为 nanographene 的生长机制为 PECVD 方法种的钻石类似于那,尽管有在 graphene 的情况中被形成的 sp2 碳原子而非象在钻石的 sp3 碳原子。这条生长途径简单、便宜、可伸缩,并且可能在象薄电影电阻器,煤气的传感器,电极材料,和透明传导性的电影那样的域里有潜在的应用程序。 | Lianchang Zhang Zhiwen Shi Yi Wang Rong Yang Dongxia Shi Guangyu Zhang | 2011 | Nano Research2011，4，3： | 12 |
| 20 | 社会生态系统理论对建设我国以人为中心阿尔茨海默病照护者支持体系的启示显示文摘全世界有4 680万痴呆患者,其中2/3为阿尔茨海默病(AD),这些患者中近1/4生活在我国。在我国,绝大多数AD患者依靠家庭照护,对AD照护者形成巨大的照护压力。随着社会老龄化的加剧,我国必须构建一个理论支持下的符合我国实际、具有广泛适用性的以人为中心的AD照护者支持体系,这对于减轻社会和家庭负担、提高AD患者及AD照护者生活质量具有重要意义。本文通过对我国AD照护者支持现状和所存在的问题进行分析,对在社会生态系统理论指导下建立我国以人为中心的AD照护者支持体系进行探讨。提出在我国现有医疗体制下,可以社会生态系统理论为指导,建立以AD患者为中心、以社区为支持主体,涵盖政府组织、制度、经费、监督等的宏观系统,社区、医院、社会团体等的中观系统以及AD照护者的微观系统的AD照护者支持体系。 | 练燕 Lily Dongxia Xiao 任辉 | 2016 | 中国全科医学2016，19，9： | 11 |
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