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	题名	作者	年代	出处	被引量
1	Capecitabine and irinotecan with and without bevacizumab for advanced colorectal cancer patients显示文摘AIM:To investigate the efficacy and safety of capecitabine plus irinotecan±bevacizumab in advanced or metastatic colorectal cancer patients. METHODS:Forty six patients with previously untreated,locally-advanced or metastatic colorectal cancer(mCRC) were recruited between 2001-2006 in a prospective open-label phaseⅡtrial,in German community-based outpatient clinics.Patients received a standard capecitabine plus irinotecan(CAPIRI) or CAPIRI plus bevacizumab(CAPIRI-BEV) regimen every 3 wk. Dose reductions were mandatory from the first cycle in cases of>grade 2 toxicity.The treatment choice of bevacizumab was at the discretion of the physician.Theprimary endpoints were response and toxicity and secondary endpoints included progression-free survival and overall survival. RESULTS:In the CAPIRI group vs the CAPRI-Bev group there were more female than male patients(47% vs 24%) ,and more patients had colon as the primary tumor site(58.8%vs 48.2%) with fewer patients having sigmoid colon as primary tumor site(5.9%vs 20.7%) .Grade 3/4 toxicity was higher with CAPIRI than CAPIRI-Bev:82%vs 58.6%.Partial response rates were 29.4%and 34.5%,and tumor control rates were 70.6%and 75.9%,respectively.No complete responses were observed.The median progression-free survival was 11.4 mo and 12.8 mo for CAPIRI and CAPIRI-Bev,respectively.The median overall survival for CAPIRI was 15 mo(458 d) and for CAPIRI-Bev 24 mo(733 d) .These differences were not statistically different.In the CAPIRI-Bev,group,two patients underwent a full secondary tumor resection after treatment,whereas in the CAPIRI group no cases underwent this procedure. CONCLUSION:Both regimens were well tolerated and offered effective tumor growth control in this outpatient setting.Severe gastrointestinal toxicities and thromboembolic events were rare and if observed were never fatal.	Markus Moehler Martin F Sprinzl Murad Abdelfattah Carl C Schimanski Bernd Adami Werner Godderz Klaus Majer Dimitri Flieger Andreas Teufel Juergen Siebler Thomas Hoehler Peter R Galle Stephan Kanzler	2009	World Journal of Gastroenterology2009，15，4：	10
2	Characterization of Hepatitis C Virus Particle Subpopulations Reveals Multiple Usage of the Scavenger Receptor BI for Entry Steps显示文摘	Viet Loan Dao Thi Christelle Granier Mirjam B. Zeisel Maryse Guérin Jimmy Mancip Ophélia Granio Fran?ois Penin Dimitri Lavillette Ralf Bartenschlager Thomas F. Baumert Fran?ois-Lo?c Cosset Marlène Dreux	2012	Journal of Biological Chemistry2012，，37：	2
3	The role and el? cacy of retrograding nailing for the treat ment of diaphyseal and distal femoral fractures: a systematic re view of the literature显示文摘	PAPADOKOSTAKIS G PAPAKOSTIDIS C DIMITRIOU R	2005	Injury2005，36，：	1
4	Agricultural Contracts:Data and Research Needs显示文摘	Hueth B Ligon E Dimitri C		0，，05：	1
5	A mathematical modelling technique for gaseous and solid fuel reburning in pulverised coalcombustors显示文摘	Dimitriou D J Kandamby N Lockwood F C	2003	Fuel2003，82，15：	1
6	The role of arte- rial embolization in controlling pelvic fracture haemorrhage: a sys- tematic review of the literature 显示文摘	Papakostidis C Kanakaris N Dimitriou R	2012	Eur J Radial2012，81，5：	1
7	Serial chito-triosidase activity estimations in neonatal systemic candi-diasis显示文摘	Labadaridis J Dimitriou E Costalos C	1998	Acta Paediatr1998，87，5：	1
8	The role of arterial embolization in controlling pelvic fracture haemorrhage:a systematic review of the literature显示文摘	Papakostidis C Kanakaris N Dimitriou R		0，，5：	1
9	The role of arterial embolization in controlling pelvic fracture hacm- orrhage:A systematic review of the literature显示文摘	Papkostidis C Kanakaris N Dimitriou R	2012	Eur J Radi- ol2012，81，5：	1
10	Serial chitotriosidase activity estimations in neonatal systemic candidiasis显示文摘	Labadaridis J Dimitriou E Costalos C	1998	Acta pediatr1998，87，5：	1
11	Contribution of redox status to hepatitis C virus E 2 envelope protein function and antigenicity显示文摘	Emmanuet Fenouilfet Dimitri LaviHete SiIvia Loureiro George Krashias Guillemette Maurin Fran?ois-Lo?c Cosset lan M Jones Eym Barbouche	2008	The Journal of biological chemist ry2008，283，26：	1
12	The role of arterial embolization in controlling pelvic fracture haemorrhage:a systematic review of the literature显示文摘	Papakostidis C Kanakaris N Dimitriou R		0，，5：	1
13	On the likeli-hood-based approach to modulation classification显示文摘	FAHED H OCTAVIA A D DIMITRIE C P	2009	IEEE Transactions on Wireless Communication2009，12，8：	1
14	The PAxpress is an ef-fective ventilatory device but has an 18% failure rate forflexible lightwand-guided tracheal intubation in anesthe-tized paralyzed patients 显示文摘	Dimitriou V Voyagis GS Iatrou C	2003	Can J Anaesth2003，50，5：	1
15	Pacing pattern and physiological responses to a 5 -rain maximal exercise bout显示文摘	Berg Kris E Kauftman Christopher L Katsavelis Dimitris C etal	2008	Journal of Strength and Conditioning Research2008，22，5：	1
16	Magnetic field-induced martensitic phase transformation in magnetic shape memory alloys:Modeling and experiments显示文摘	Krishnendu Haldar Dimitris C Lagoudas	2014	Journal of the Mechanics and Physics of Solids2014，，69：	1
17	The effects of rosuvastatin alone or in combination with fenofibrate or omega 3 fatty acids on inflammation and oxidative stress in patients with mixed dyslipidemia显示文摘	Aris P Agouridis Vasilis Tsimihodimos Theodosios D Filippatos Andromachi A Dimitriou Costantinos C Tellis Moses S Elisaf Dimitri P Mikhailidis Alexandros D Tselepis	2011	Expert Opinion on Pharmacotherapy2011，，17：	1
18	The role and efficacy of retrograding nailing for the treatment of diaphyseal and distal femoral fractures:a systematic review of the literature显示文摘	Papadokostakis G Papakostidis C Dimitriou R	2005	Injury2005，36，7：	1
19	Effects of Non-planar Geometries and Volumetric Expansion in the Modeling of Oxidation in Titanium显示文摘	Pavlin B Entchev Dimitris C Lagoudas John C Slattery	2001	International Jounal of Engineering Science2001，39，：	1
20	Remifentanil pre- venting hemodynamic changes during laparoscopic adrenalectomy for pheochromocytoma 显示文摘	Dimitriou V Chantzi C Zogogiannis I	2006	Middle East J Anesthesiol2006，18，：	1

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