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| 1 | FUZZY PRETOPOLOGICALSPACES, AN EXTENSIONALTOPOLOGICAL EXTENSION OF FTS显示文摘The category of fuzzy pretopological spaces is introduced, and it is proved that this category is a well-fibred extensional topological construct, and it is a finally dense extension of the category of fuzzy topological spaces. Moreover this category contains both the category of pretopological spaces and the category of probabilistic neighbourhood spaces as simultaneously bireflective and bicoreflective full subcategories. | ZHANG DEXUE(Department of Mathematics, Sichuan University, Chengdu 610064, China.)(Project supported by the National Natural Science Foundation of China.) | 1999 | Chinese Annals of Mathematics,Series B1999，20，3： | 3 |
| 2 | Finite element simulation on percolation of low permeability reservoir with permeability anisotropy显示文摘In low permeability porous media which permeability anisotropy is ubiquitous,the percolation of fluid no longer follows linear Darcy’s Law.Oil-water two phase flow equation of low permeability reservoir with permeability anisotropy is established based on generalized Darcy’s law and starting pressure gradient,corresponding finite element program is developed and simulated based on the Finite Element Program Generator system (FEPG).The results show that energy-gathering exists in the flow event of flowing area front in low permeability reservoir.In the process of energy-gathering,the flow velocity changed little but increased rapidly as soon as the pressure gradient exceeded the starting pressure gradient of the reservoir,then gradually stabilized.The greater the starting pressure gradient is,the greater the near wellbore pressure drop is,the smaller the area influenced by the reservoir pressure changes caused by water injection and oil recovery.The greater the starting pressure gradient is,the lower the water saturation in same point of the reservoir is,the smaller the water flood swept area is.There will be more difficulties in water injection to the same extent. | ZHI Qingong ZHAO Yizhong CHENG Yuanfang SUN Dexu DU Peng | 2012 | Global Geology2012，15，4： | 2 |
| 3 | Identification of EGF as an Important Regulator for Promoting CYP3A4 Expression in Human Embryonic Stem Cell-Derived Hepatocytes Using TALEN-Based Gene Targeting显示文摘Functional human hepatocytes are one of the most significant tools for studying drug absorption,distribution,metabolism and excretion/toxicity (ADME/Tox),especially for applications in preclinical drug development (Sahi et al.,2010;Godoy et al.,2013).They provide the closest in vitro model to the human liver and the only model that mimics the drug metabolic profiles found in vivo.However,these cells lose their metabolic function rapidly and dramatically during the in vitro culture process,which largely hinders their wider application in drug development (Sahi et al.,2010;Godoy et al.,2013).To overcome this obstacle,it is important to regulate the activities of key genes which are responsible for the detoxification metabolic function of human hepatocytes. | Ming YinaCollege of Veterinary Medicine Jilin University Huan Yang Xiaohua Su Ziyi Li Zhanpeng Yue Xueming Zhang Da Sun Yan Shi Dexue Li | 2014 | Journal of Genetics and Genomics2014，41，6： | 2 |
| 4 | The Change-Base Issue for Ω-Categories显示文摘Let G:Ω→Ω′be a closed unital map between commutative,unital quantales. G induces a functor G from the category of Ω-categories to that of Ω′-categories.This paper is concerned with some basic properties of G.The main results are:(1) when Ω,Ω′are integral,G:Ω→Ω′and F:Ω′→Ωare closed unital maps,F is a left adjoint of G if and only if F is a left adjoint of G;(2) G is an equivalence of categories if and only if G is an isomorphism in the category of commutative unital quantales and closed unital maps; and (3) a sufficient condition is obtained for G to preserve completeness in the sense that GA is a complete Ω′-category whenever A is a complete Ω-category. | Chengling FANG Dexue ZHANG | 2008 | Chinese Annals of Mathematics,Series B2008，29，4： | 2 |
| 5 | Hypothalamic paraventricular nucleus neurons activated by estrogen GPER1 receptors promote anti-inflammation effects in the early stage of colitis显示文摘The hypothalamus-pituitary-adrenal(HPA)axis is known to mediate gut-brain interaction,and the pathological inflammatory process in the intestine can induce HPA axis involved'fight or flight response to suppress or facilitate intestinal inflammation.Hypothalamic paraventricular nucleus(PVN)neurons are responsible for controlling the HPA axis activity,but their exact role in modulating intestinal inflammation remains unclear.In this study,we used the dextran sulfate sodium(DSS)-induced mice colitis model,gene editing,and RNA interference to determine the effects of PVN neurons on intestinal inflammation.We found that at the early stage(third day)after DSS treatment,there was a mild inflammation in the colorectal area and an increased neuron activatio n in the PVN but not in the adjace nt area.At the same time,~80% of activated PVN n eurons also expressed novel estrogen GPER1 receptor.The colitis noticeably worsened in GPER1-knockout mice and local PVN GPER1-knockdown mice.These results indicated that PVN GPER1 positive neurons potentially have a protective function during the early stages of DSS-induced colitis,and this may be a mechanism by which the central nervous system attempts to suppress intestinal inflammation to achieve self-protection. | Tao Jiang Ruoxi Wang Wen Yin Yuxi Zhou Dexu Kong Saihong Xu Po Gao Weifeng Yu Yingfu Jiao Daxiang Wen | 2019 | Acta Biochimica et Biophysica Sinica2019，51，12： | 1 |
| 6 | On the relationship between several basil category in fuzzy topology 显示文摘 | Zhang Dexue | 2002 | Questions Mathematicae2002，，25： | 1 |
| 7 | On the relationship between several basic category in fuzzy topology 显示文摘 | Zhang Dexue | 2002 | Questions Mathematicae2002，25，3： | 1 |
| 8 | Fuzzy preorder and fuzzy topology显示文摘 | Lai Hongliang Zhang Dexue | 2006 | Fuzzy Sets and Systems2006，157，4： | 1 |
| 9 | A Neural Computation Structure for Solving Functional Equations with Functional Networks显示文摘 | Zhou Yongquan He Dexu Jiao Licheng | 2005 | Journal of Information and Computational Science2005，2，4： | 1 |
| 10 | Approximate Factorization of Univariate Polynomials Using Functional Networks显示文摘 | He Dexu Nong Zheng Zhou Yongquan | 2005 | Journal of Information and Computational Science2005，2，3： | 1 |
| 11 | In vivo chondrogenesis of adult bone-marrow-derived autologous mesenchymal stem cells显示文摘 | Jinwu Chen Changyong Wang Shuanghong Lü Junzheng Wu Ximin Guo Cuimi Duan Lingzhi Dong Ying Song Junchuan Zhang Dianying Jing Linbo Wu Jiandong Ding Dexue Li | 2005 | Cell and Tissue Research2005，，3： | 1 |
| 12 | Study on Bi- directional Controllable Flexible Bending Joints based on E- longation Artificial Muscles 显示文摘 | Dexu Geng Ji Zhao Lei Zhang Yunwei Zhao | 2011 | Applied Mechanics and Ma- terials2011，，46： | 1 |
| 13 | Study on Bidirec- tional Controllable Flexible Bending Joints based on Elon- gation Artificial Muscles 显示文摘 | GENG Dexu ZHAO Ji ZHANG Lei | 2011 | Applied Mechanics and Ma- terials2011，46，： | 1 |
| 14 | Expression localization of Bmil in mice testis显示文摘 | Zhang Shiqing Li Dexue Li Enzhong | 2008 | Mol Cell Endocrinol2008，287，12： | 1 |
| 15 | Weakly induced modifications of topologuical spaces显示文摘 | Zhang Dexue Liu Yingming | 1993 | Acta Math Sinica1993，36，： | 1 |
| 16 | Salmon calcitonin in the treatment of elderly women with type 2 diabetes complicated with osteoporosis显示文摘 | Dexue L Yueyue Z | 2014 | Pak J Pharm Sei2014，27，6： | 1 |
| 17 | Categories isomorphic to FNS 显示文摘 | ZHANG Dexue XU Luoshan | 1999 | Fhlzzy Sets and Systems1999，104，3： | 1 |
| 18 | The influence of chitosan hydrogel on stem cell engraftment, survival and homing in the ischemic myocardial microenvironment显示文摘 | Zhiqiang Liu Haibin Wang Yan Wang Qiuxia Lin Anning Yao Feng Cao Dexue Li Jin Zhou Cuimi Duan Zhiyan Du Yanmeng Wang Changyong Wang | 2011 | Biomaterials2011，，11： | 1 |
| 19 | Overexpression and involvement of special AT‐rich sequence binding protein 1 in multidrug resistance in human breast carcinoma cells显示文摘 | Qing‐QuanLi Zhong‐QingChen Jing‐DaXu Xi‐XiCao QiChen Xiu‐PingLiu Zu‐DeXu | 2009 | Cancer Science2009，，1： | 1 |
| 20 | On the relationship between several basic categories in fuzzy topology显示文摘 | ZHANG Dexue | 2002 | Quaest Math2002，25，3： | 1 |
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