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| 1 | Colometer:A real-time quality feedback system for screening colonoscopy显示文摘AIM:To investigate the performance of a new software-based colonoscopy quality assessment system.METHODS:The software-based system employs a novel image processing algorithm which detects the levels of image clarity,withdrawal velocity,and level of the bowel preparation in a real-time fashion from live video signal.Threshold levels of image blurriness and the withdrawal velocity below which the visualization could be considered adequate have initially been determined arbitrarily by review of sample colonoscopy videos by two experienced endoscopists.Subsequently,an overall colonoscopy quality rating was computed based on the percentage of the withdrawal time with adequate visualization(scored 1-5;1,when the percentage was 1%-20%;2,when the percentage was 21%-40%,etc.).In order to test the proposed velocity and blurriness thresholds,screening colonoscopy withdrawal videos from a specialized ambulatory colon cancer screening center were collected,automatically processed and rated.Quality ratings on the withdrawal were compared to the insertion in the same patients.Then,3 experienced endoscopists reviewed the collected videos in a blinded fashion and rated the overall quality of each withdrawal(scored 1-5;1,poor;3,average;5,excellent) based on 3 major aspects:image quality,colon preparation,and withdrawal velocity.The automated quality ratings were compared to the averaged endoscopist quality ratings using Spearman correlation coefficient.RESULTS:Fourteen screening colonoscopies were assessed.Adenomatous polyps were detected in 4/14(29%) of the collected colonoscopy video samples.As a proof of concept,the Colometer software rated colonoscope withdrawal as having better visualization than the insertion in the 10 videos which did not have any polyps(average percent time with adequate visualization:79% ± 5% for withdrawal and 50% ± 14% for insertion,P < 0.01).Withdrawal times during which no polyps were removed ranged from 4-12 min.The median quality rating from the automated system and the reviewers was 3.45 [interquartile range(IQR),3.1-3.68] and 3.00(IQR,2.33-3.67) respectively for all colonoscopy video samples.The automated rating revealed a strong correlation with the reviewer's rating(ρ coefficient= 0.65,P = 0.01).There was good correlation of the automated overall quality rating and the mean endoscopist withdrawal speed rating(Spearman r coefficient= 0.59,P = 0.03).There was no correlation of automated overall quality rating with mean endoscopists image quality rating(Spearman r coefficient= 0.41,P = 0.15).CONCLUSION:The results from a novel automated real-time colonoscopy quality feedback system strongly agreed with the endoscopists' quality assessments.Further study is required to validate this approach. | Dobromir Filip Xuexin Gao Leticia Angulo-Rodriguez Martin P Mintchev Shane M Devlin Alaa Rostom Wayne Rosen Christopher N Andrews | 2012 | World Journal of Gastroenterology2012，18，32： | 2 |
| 2 | Deciphering the biology of My cobacterium tuberculosis from the complete genome sequence 显示文摘 | Cole S T Brosch R Parkhill J Gamier T Churcher C Harris D Gordon S V Eiglmeier K Gas S Barry C E Tekaia F Badcock K Basham D Brown D Chillingworth T Cormor R Davies R Devlin K FeltweU T Gentles S Hamlin N Holroyd S Hornsby T Jagels K Kroghs A McLean J Moule S Murphy L Oliver K Osborne J Quail M A Rafandream M A Rogers J Rutter S Seeger K Skelton J Squaraes R Squares S Sulston J E Taylo K Whitehead S Barrell B G | 1998 | Nature1998，393，： | 1 |
| 3 | Progression of prostate cancer: multiple pathways to androgen independence显示文摘 | Devlin HL Mudryj M | 2009 | Cancer Lett2009，274，2： | 1 |
| 4 | Determination of Absolute Configuration Using Ab Initio Calculation of Optical Rotation显示文摘 | STEPHENS P J DEVLIN F J CHEESEMAN J R FRISCH M J | 2003 | Chirality2003，15，： | 1 |
| 5 | Effect of mechanical shear on the thin-film properties of base oil-polymer mixtures显示文摘 | M T Devlin T Hammock T-C Jao | 2002 | Lubrication Science2002，，14： | 1 |
| 6 | Assessing the impact of nutrient enrichment inestuaries:Susceptibility to eutrophication显示文摘 | Painting S J Devlin M J Malcolm S J | 2007 | MarinePollution Bulletin2007，55，： | 1 |
| 7 | Investigations into resting-state connectivity using independent component analysis显示文摘 | Beckmann CF DeLuca M Devlin JT | 2005 | Philos Trans R Soc Lond B Bioi Sci2005，360，1457： | 1 |
| 8 | Morphology and the Internal Structure of Words 显示文摘 | DEVLIN J T JAMISON H L MATTHEWS P M | 2004 | Pro- ceedings of the National Academy of Sciences2004，101，14： | 1 |
| 9 | ATF frictionproperties and shift quality显示文摘 | Cameron T M McCombs T Devlin M | 2004 | SAE2004，，： | 1 |
| 10 | An Internet- ready database for prospective randomized clinical trials of high-dose-rate brachytherapy for adenocarcinoma of the pros- tate显示文摘 | DEVLIN P M BRUS C R KAZAKIN J | 2002 | Int J Radiat Oncol Biol Phys2002，53，1： | 1 |
| 11 | Comparison of five methods for assessing impacts of nutrient enrichment using estuarine case studies显示文摘 | DEVLIN M BRICKER S PAINTING S | 2011 | Biogeochemistry2011，106，2： | 1 |
| 12 | Exposure to particulate matter, volatile organic compounds, and other air pollutants inside patrol cars显示文摘 | Riediker M Williams R Devlin R | 2003 | Environmental Science & Technology2003，37，： | 1 |
| 13 | Hypermethylation of Fads2 and altered hepatic fatty acid and phospholipid metabo- lism in mice with hyperhomocysteinemia显示文摘 | DEVLIN A M SINGH R WADE R E | 2007 | J Biol Chem2007，282，37： | 1 |
| 14 | The heritability of IQ 显示文摘 | Devlin B Daniels M Roeder K | 1997 | Nature1997，388，6641： | 1 |
| 15 | Assessment of the eu- trophication status of the Great Barrier Reef lagoon (Australia) 显示文摘 | Brodie J E Devlin M Haynes D | 2011 | Biagoochemistry2011，106，2： | 1 |
| 16 | Interface of biotechnology and ecology for environmental risk assessments of transgenic fish 显示文摘 | Devlin R H Sundstrom L F Muir W M | 2006 | Trends Biotechnol2006，24，2： | 1 |
| 17 | Calculation of Optical Rotation Using Density Functional Theory显示文摘 | STEPHENS P J DEVLIN F J CHESEMAN J R FRISH M J | 2001 | J Phys Chem A2001，105，： | 1 |
| 18 | Production of germline transgenic Pacific salmonids with dramatically increased growth performance 显示文摘 | Devlin R H Yesaki T Y Donaldson E M | 1995 | Can J Fish Aquat Sci1995，52，： | 1 |
| 19 | Ahybrid discrete-continuum mathematical model of patternprediction in the developing retinal 显示文摘 | MCDOUGALL S R WATSON M G DEVLIN A H | 2012 | Bull Math Biol2012，74，： | 1 |
| 20 | Establishing boundary classes for the classification of UK marine waters using phytoplankton communities显示文摘 | DEVLIN M J BEST M COATES D | 2007 | Marine Pollution Bulletin2007，55，16： | 1 |
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