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| 1 | Colometer:A real-time quality feedback system for screening colonoscopy显示文摘AIM:To investigate the performance of a new software-based colonoscopy quality assessment system.METHODS:The software-based system employs a novel image processing algorithm which detects the levels of image clarity,withdrawal velocity,and level of the bowel preparation in a real-time fashion from live video signal.Threshold levels of image blurriness and the withdrawal velocity below which the visualization could be considered adequate have initially been determined arbitrarily by review of sample colonoscopy videos by two experienced endoscopists.Subsequently,an overall colonoscopy quality rating was computed based on the percentage of the withdrawal time with adequate visualization(scored 1-5;1,when the percentage was 1%-20%;2,when the percentage was 21%-40%,etc.).In order to test the proposed velocity and blurriness thresholds,screening colonoscopy withdrawal videos from a specialized ambulatory colon cancer screening center were collected,automatically processed and rated.Quality ratings on the withdrawal were compared to the insertion in the same patients.Then,3 experienced endoscopists reviewed the collected videos in a blinded fashion and rated the overall quality of each withdrawal(scored 1-5;1,poor;3,average;5,excellent) based on 3 major aspects:image quality,colon preparation,and withdrawal velocity.The automated quality ratings were compared to the averaged endoscopist quality ratings using Spearman correlation coefficient.RESULTS:Fourteen screening colonoscopies were assessed.Adenomatous polyps were detected in 4/14(29%) of the collected colonoscopy video samples.As a proof of concept,the Colometer software rated colonoscope withdrawal as having better visualization than the insertion in the 10 videos which did not have any polyps(average percent time with adequate visualization:79% ± 5% for withdrawal and 50% ± 14% for insertion,P < 0.01).Withdrawal times during which no polyps were removed ranged from 4-12 min.The median quality rating from the automated system and the reviewers was 3.45 [interquartile range(IQR),3.1-3.68] and 3.00(IQR,2.33-3.67) respectively for all colonoscopy video samples.The automated rating revealed a strong correlation with the reviewer's rating(ρ coefficient= 0.65,P = 0.01).There was good correlation of the automated overall quality rating and the mean endoscopist withdrawal speed rating(Spearman r coefficient= 0.59,P = 0.03).There was no correlation of automated overall quality rating with mean endoscopists image quality rating(Spearman r coefficient= 0.41,P = 0.15).CONCLUSION:The results from a novel automated real-time colonoscopy quality feedback system strongly agreed with the endoscopists' quality assessments.Further study is required to validate this approach. | Dobromir Filip Xuexin Gao Leticia Angulo-Rodriguez Martin P Mintchev Shane M Devlin Alaa Rostom Wayne Rosen Christopher N Andrews | 2012 | World Journal of Gastroenterology2012，18，32： | 2 |
| 2 | Determination of Absolute Configuration Using Ab Initio Calculation of Optical Rotation显示文摘 | STEPHENS P J DEVLIN F J CHEESEMAN J R FRISCH M J | 2003 | Chirality2003，15，： | 1 |
| 3 | Morphology and the Internal Structure of Words 显示文摘 | DEVLIN J T JAMISON H L MATTHEWS P M | 2004 | Pro- ceedings of the National Academy of Sciences2004，101，14： | 1 |
| 4 | An Internet- ready database for prospective randomized clinical trials of high-dose-rate brachytherapy for adenocarcinoma of the pros- tate显示文摘 | DEVLIN P M BRUS C R KAZAKIN J | 2002 | Int J Radiat Oncol Biol Phys2002，53，1： | 1 |
| 5 | Calculation of Optical Rotation Using Density Functional Theory显示文摘 | STEPHENS P J DEVLIN F J CHESEMAN J R FRISH M J | 2001 | J Phys Chem A2001，105，： | 1 |
| 6 | American Brachytherapy Society recommends no change for prostate permanent implant dose prescrip- tions using iodine-125 or palladium-103显示文摘 | RIVARD M J BUTLER W M DEVLIN P M | 2007 | Brachy- therapy2007，6，： | 1 |
| 7 | A single-blind, cross-over trial of hip abductor strength training to improve Timed Up & Go performance in patients with unilateral,transfemoral amputation 显示文摘 | Pauley T Devlin M Madan-Sharma P | 2014 | J Rehabil Med2014，46，3： | 1 |
| 8 | Inrtaoperative neurophysiologic monitoring: focus on cervical myelopathy and related issues显示文摘 | Devlin V J Anderson P A Schwartz D M | 2006 | Spine2006，6，14： | 1 |
| 9 | Determination of the absolute configurations of natural products via density functional theory calculations of optical rotation,dectronic circular dichroism,and vibrational circular dichroism:the cytotoxic sesquiterpene natural products quadrone,suberosenone,suberosanone,and suberosenol a acetate显示文摘 | Stephens P J McCann D M Devlin F J | 2006 | Journal of Natural Products2006，69，7： | 1 |
| 10 | Influence of methanol on plant growth显示文摘 | Devlin R M Bhowmik P C Karezmarczyk S J | | 0，，04： | 1 |
| 11 | A genomic analysis of the shade avoidance response in Arabidopsis 显示文摘 | DEVLIN P F YANOVSKY M J KAY S A | 2003 | Plant Physiology2003，133，4： | 1 |
| 12 | Health effects of outdoor air pollution显示文摘 | Bascom R Bromber P A Costa D L Devlin R Dockery D W Frampton M W Lambert W Samet J M Speizer F E and Utell M | | 0，，： | 1 |
| 13 | The 'place' of inter- pretation: A new approach to the evaluation of interpretation显示文摘 | Stewart E J Hayward B M Devlin P J | 1998 | Tourism management1998，19，3： | 1 |
| 14 | Controversies in the management of primary sclerosingcholangitis显示文摘Primary sclerosing cholangitis(PSC) remains a rare but significant disease, which affects mainly young males in association with inflammatory bowel disease. There have been few advances in the understanding of the pathogenesis of the condition and no therapeutics with proven mortality benefit aside from liver transplantation. There remain areas of controversy in the management of PSC which include the differentiation from other cholangiopathies, in particular immunoglobulin G4 related sclerosing cholangitis, the management of dominant biliary strictures, and the role of ursodeoxycholic acid. In addition, the timing of liver transplantation in PSC remains difficult to predict with standard liver severity scores. In this review, we address these controversies and highlight the latest evidence base in the management of PSC. | Jeremy S Nayagam Stephen P Pereira John Devlin Phillip M Harrison Deepak Joshi | 2016 | World Journal of Hepatology2016，8，5： | 1 |
| 15 | Myostatin, a transforming growth factor-beta superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarct显示文摘 | Sharma M Kambadur R Matthews K G Somers W G Devlin G P Conaglen J V Fowke P J Bass J J | | J Cell Phys0，，： | 1 |
| 16 | A genomic anal- ysis of the shade avoidance response in Arabidopsis 显示文摘 | DEVLIN P F YANOVSKY M J KAY S A | 2003 | Plant Physiology2003，133，4： | 1 |
| 17 | Intraoperative neurophysiologic monitoring: focus on cervical myelopathy and related issues显示文摘 | Devlin V J Anderson P A Schwartz D M | 2006 | The Spine Journal2006，6，6： | 1 |
| 18 | Influence of acid functionalization on the cardiopulmonary toxicity of carbon nanotubes and carbon black particles in mice 显示文摘 | TONG H MCGEE J K SAXENA R K KODAVANTI U P DEVLIN R B GILMOUR M 1 | 2009 | Toxicol Appl Pharmacol2009，239，： | 1 |
| 19 | Managing a complex river catchment:a case study on the River Almond显示文摘 | POLLARD P DEVLIN M HOLLOWAY D | 2001 | The Science of the Total Environment2001，265，1： | 1 |
| 20 | Many hands make light work显示文摘 | DEVLIN P F CHRISTIE J M TERRY M J | 2007 | Journal of Eccperimental Botany2007，58，： | 1 |
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