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| 1 | Alcohol dehydrogenase: A potential new marker for diagnosis of intestinal ischemia using rat as a model显示文摘AIM: Intestinal ischemia (Ii) is an abdominal emergency due to blockade of the superior mesenteric artery resulting in 60-100% mortality if diagnosed late. Changes in several biochemical parameters such as D (-)-lactate, Creatinine kinase isoenzymes and lactate dehydrogenase suggested for early diagnosis, lack specificity and sensitivity. Therefore a biochemical parameter with greater sensitivity needs to be identified.METHODS: Wistar male rats were randomly assigned into two groups; control sham operated (n = 24) and ischemic test (n = 24) group. Superior mesenteric arterial occlusion was performed in the ischemic test group for 1 h. Alcohol dehydrogenase (ADH) was estimated in blood from portal vein, right ventricle of heart, dorsal aorta (DA) and inferior vena cava (IVC). The Serum glutamic acid pyruvate transaminase (SGPT) was also estimated in blood from portal vein and right ventricle of heart.RESULTS: A significant increase (P<0.001) in the levels of ADH in both portal blood as well as heart blood of the test group (232.72±99.45 EU and 250.85±95.14 EU, respectively)as compared to the control group (46.39±21.69 EU and 65.38±30.55 EU, respectively) were observed. Similarly,increased levels of ADH were observed in blood samples withdrawn from DA and IVC in test animals (319.52±80.14EU and 363.90±120.68 EU, respectively) as compared to the control group (67.68±63.22 EU and 72.50±58.45 EU,respectively). However, in test animals there was significant increase in SGPT in portal blood (P = 0.054) without much increase in heart blood.CONCLUSION: Significant increase in the levels of ADH in portal and heart blood within 1 h of SMA occlusion without increase in SGPT in heart blood, suggests that the origin of ADH is from ischemic intestine and not from liver. Similarly, raised ADH levels were found in DA and IVC as well. IVC blood does represent peripheral blood sample. A raised level of ADH in test animals confirms it to be a potential marker in the early diagnosis of Ii. | Upendra R Gumaste Mukund M Joshi Devendra T Mourya Pradip V Barde Ghanshyam K Shrivastav Vikram S Ghole | 2005 | World Journal of Gastroenterology2005，11，6： | 9 |
| 2 | An X-band microwave life-detection system显示文摘 | Devendra M Wang H | 1986 | IEEE Trans BMS1986，33，7： | 1 |
| 3 | On Channel or Thogo-nalization Using Space-time Block Coding with Partial Feedback显示文摘 | Klutto M J Giridhar K Devendra J | | 0，，06： | 1 |
| 4 | Extraction separation of Ir(Ⅲ) and Rh (Ⅲ) with Cyanex 923 from chloride media: a possible recovery from spent autocatalysts 显示文摘 | DEVENDRA V C PURUSHOTFAM M D | 2002 | J Chem Technol Biotechnol2002，77，8： | 1 |
| 5 | Application of ozone based treatmentsof secondary effluents显示文摘 | Smriti T Vinita P Devendra M T | 2011 | Bioresource Technology2011，102，： | 1 |
| 6 | Application of ozone based treatments of secondary effluents 显示文摘 | Smriti T Vinita P Devendra M T | 2011 | Bioresource Technology2011，102，： | 1 |
| 7 | Depressed femoral condyle fracture显示文摘 | Devendra M Christopher C Jonathan K | 2008 | Injury Extra2008，39，： | 1 |
| 8 | Jaggery: a novel substrate for pullulan production by Aureobasiudium pullulans (FR- T)显示文摘 | S V N Vijayendra Devendra Bansal M S Prasad | 2001 | Processs Biochemistry2001，37，： | 1 |
| 9 | The regulatory role of TGF-b in airway remodeling in asthma显示文摘 | ToluwaloPe M Richard FM Devendra KA | 2007 | Immunol Cell Biol2007，27，： | 1 |
| 10 | Anti-microbial activity of a new vaginal contraceptive NIM-76 from neem oil (Azadirachta indica)显示文摘 | M SaiRam G Ilavazhagan S.K Sharma S.A Dhanraj B Suresh M.M Parida A.M Jana Kumar Devendra W Selvamurthy | 2000 | Journal of Ethnopharmacology2000，，3： | 1 |
| 11 | Fire- and heatresistant laminating resins based on maleimido-substituted aromatic cyclotriphosphazenes显示文摘 | Devendra K George M F John A Parker | 1983 | Macromolecules1983，16，： | 1 |
| 12 | Dielectric materials for electrowetting-on-dielectric actuation 显示文摘 | HONG S D DEVENDRA K M | 2010 | Mi- crosyst Technol2010，16，3： | 1 |
| 13 | Formation of low angle boundaries in Ni-based superalloys显示文摘 | D'SOUZA N NEWELL M DEVENDRA K | 2005 | Materials Science and Engineering A-Structural Materials:Properties Microstructure and Processing2005，413，6： | 1 |
| 14 | Nitrate availability under low irradiance and its effect on the nitrate reductase activity 显示文摘 | DEVENDRA R REDDY V S | 1981 | New Phytol1981，88，： | 1 |
| 15 | Cellular, molecular and immunological mechanisms in the pathophysiology of vein graft intimal hyperplasia显示文摘 | AMIT K MITRA DEEPAK M GANGAHAR DEVENDRA K AG RAWAL | 2006 | Immunology and Cell Biology2006，84，2： | 1 |
| 16 | The effects of HIV on the sensitivity of a whole blood IFN-gamma release assay in Zambian adults with active tuberculo- sis显示文摘 | Raby E Moyo M Devendra A | 2008 | Plos One2008，3，6： | 1 |
| 17 | Extraction separation of Ir(Ⅲ) and Rh(Ⅲ) witn Cyanex 923 from chloride media: a possible recovery from spent autocatalysts 显示文摘 | Purushottam M Dhadke | 2002 | J Chem Technol Biotechnol2002，77，： | 1 |
| 18 | Formation of low angle boundaries in Ni-based superalloys 显示文摘 | Souza N D Newell M Devendra K | 2005 | Materials Science and Engineering A2005，412，： | 1 |
| 19 | Role of dendrite branching and growth kinetics in the formation of low angle boundaries in Ni-base superalloys 显示文摘 | Newell M Devendra K Jennings P A | 2005 | Materials Science and Engineering A2005，412，： | 1 |
| 20 | Allele-specific PCR method based on rfbS sequence for distinguishing Salmonella gallinarum from Salmonella pullorum:serotype-specific rfbS sequence polymorphism显示文摘 | DEVENDRA H S PARK J H CHO M R | 2005 | J Microbiol Methods2005，60，： | 1 |
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