|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Liver venous deprivation versus portal vein embolization before major hepatectomy:future liver remnant volumetric and functional changes显示文摘Background:We previously showed that embolization of portal inflow and hepatic vein(HV)outflow(liver venous deprivation,LVD)promotes future liver remnant(FLR)volume(FLR-V)and function(FLR-F)gain.Here,we compared FLR-V and FLR-F changes after portal vein embolization(PVE)and LVD.Methods:This study included all patients referred for liver preparation before major hepatectomy over 26 months.Exclusion criteria were:unavailable baseline/follow-up imaging,cirrhosis,Klatskin tumor,two-stage hepatectomy.99mTc-mebrofenin SPECT-CT was performed at baseline and at day 7,14 and 21 after PVE or LVD.FLR-V and FLR-F variations were compared using multivariate generalized linear mixed models(joint modelling)with/without missing data imputation.Results:Baseline FLR-F was lower in the LVD(n=29)than PVE group(n=22)(P<0.001).Technical success was 100%in both groups without any major complication.Changes in FLR-V at day 14 and 21(+14.2%vs.+50%,P=0.002;and+18.6%vs.+52.6%,P=0.001),and in FLR-F at day 7,14 and 21(+23.1%vs.+54.3%,P=0.02;+17.6%vs.+56.1%,P=0.006;and+29.8%vs.+63.9%,P<0.001)differed between PVE and LVD group.LVD(P=0.009),age(P=0.027)and baseline FLR-V(P=0.001)independently predicted FLR-V variations,whereas only LVD(P=0.01)predicted FLR-F changes.After missing data handling,LVD remained an independent predictor of FLR-V and FLR-F variations.Conclusions:LVD is safe and provides greater FLR-V and FLR-F increase than PVE.These results are now evaluated in the HYPERLIV-01 multicenter randomized trial. | Boris Guiu François Quenet Fabrizio Panaro Lauranne Piron Christophe Cassinotto Astrid Herrerro François-Régis Souche Margaux Hermida Marie-Ange Pierredon-Foulongne Ali Belgour Serge Aho-Glele Emmanuel Deshayes | 2020 | Hepatobiliary Surgery and Nutrition2020，9，5： | 10 |
| 2 | Optimization of the future remnant liver:review of the current strategies in Europe显示文摘Liver resection still represent the treatment of choice for liver malignancies,but in some cases inadequate future remnant liver(FRL)can lead to post hepatectomy liver failure(PHLF)that still represents the most common cause of death after hepatectomy.Several strategies in recent era have been developed in order to generate a compensatory hypertrophy of the FRL,reducing the risk of post hepatectomy liver failure.Portal vein embolization,portal vein ligation,and ALLPS are the most popular techniques historically adopted up to now.The liver venous deprivation and the radio-embolization are the most recent promising techniques.Despite even more precise tools to calculate the relationship among volume and function,such as scintigraphy with^(99m)Tc-mebrofenin(HBS),no consensus is still available to define which of the above mentioned augmentation strategy is more adequate in terms of kind of surgery,complexity of the pathology and quality of liver parenchyma.The aim of this article is to analyse these different strategies to achieve sufficient FRL. | Riccardo Memeo Maria Conticchio Emmanuel Deshayes Silvio Nadalin Astrid Herrero Boris Guiu Fabrizio Panaro | 2021 | Hepatobiliary Surgery and Nutrition2021，10，3： | 4 |
| 3 | Insight into the cellular uptake mechanism of a secondaryamphipathic cell-penetrating peptide for siRNA delivery显示文摘 | Konate K Crombez L Deshayes S | 2010 | Biochemistry2010，49，16： | 1 |
| 4 | Delivery of proteins and nucleic acids using a non-covalent peptide-based strategy 显示文摘 | Deshayes S Morris M Heitz F | 2008 | Adv Drug Deliv Rev2008，60，45： | 1 |
| 5 | Cell-penetrating peptides: from molecular mechanisms to therapeutics 显示文摘 | Morris MC Deshayes S Heitz F | 2008 | Biol Cell2008，100，4： | 1 |
| 6 | Angiotensin receptors:a new role in cancer显示文摘 | DESHAYES F NAHMIAS C | 2005 | Trends Endocrinol Metab2005，16，7： | 1 |
| 7 | Insight into the mechanism of internalization of the cell-penetrating carrier peptide Pep-1 throngh conformational analysis显示文摘 | Deshayes S Heitz A Morris MC | 2004 | Biochemistry2004，43，6： | 1 |
| 8 | Fluorescence technologies for monitoring interactions between biological molecules in vitro显示文摘 | Deshayes S Divita G | 2013 | Prog Mol Biol Transl Sci2013，113，： | 1 |
| 9 | Insight into the mechanism of internalization of the cell-penetrating carrier peptide Pep-1 through conformational analysis显示文摘 | DESHAYES S HEITZ A MORRIS M C | 2004 | Biochemistry2004，43，6： | 1 |
| 10 | Cell-penetrating peptides:tools for intracellular delivery of therapeutics显示文摘 | Deshayes S Morris MC Divita G | 2005 | Cell Mol Life Sci2005，62，16： | 1 |
| 11 | On the mechanism of non-endosomial peptide-mediated cellular delivery of nucleic acids显示文摘 | DESHAYES S GERBAL-CHALOIN S MORRIS M C | 2004 | Biochim Biophys Acta2004，1667，2： | 1 |
| 12 | SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP) 显示文摘 | Vucic D Deshayes K Ackerly H | | J Biol Chem0，277，12： | 1 |
| 13 | A non-covalent peptide-based strategy for protein and peptide nucleic acid delivery显示文摘 | GROS E DESHAYES S MORRIS M C | 2006 | Biochim Biophys Acta2006，1758，3： | 1 |
| 14 | SMAC Negatively Regulates the Anti-apoptotic Activity of Melanoma Inhibitor of Apoptosls (ML-IAP) 显示文摘 | Vucic D Deshayes K Ackerly H | 2002 | J Biol Chem2002，277，12： | 1 |
| 15 | Use of freeze-dried plasma in French intensive care unit in Afghanistan显示文摘 | Martinaud C Ausset S Deshayes AV | | 0，，06： | 1 |
| 16 | Additional Benefit of F - 18 FDG PET/CT in the Staging and Follow - up of Pediatric Rhabdomyo- sarcoma 显示文摘 | Ricard F Cimarelli S Deshayes E | 2011 | Clin Nucl Med2011，36，8： | 1 |
| 17 | Rubisco small subunit of Coffea arabica : cDNA sequence, gene cloning and promoter analysis in transgenic tobacco plants显示文摘 | Pierre Marraccini Carine Courjault Victoria Caillet Fran?oise Lausanne Brigitte Lepage W.John Rogers Sylviane Tessereau Alain Deshayes | 2003 | Plant Physiology and Biochemistry2003，，1： | 1 |
| 18 | SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis(ML2IAP)显示文摘 | Vucic D Deshayes K Ackerly H | 2002 | J Biol Chem2002，277，12： | 1 |
| 19 | SMAC negatively regulates the antiapoptotic activity of melanoma inhibitor of apoptesis ( ML - IAP) 显示文摘 | Vucic D Deshayes K Aekerly H | 2002 | Biol Chem2002，54，12： | 1 |
| 20 | Abnormal production of the TNF-homologue APRIL increases the proliferation of human malignant glioblastoma cell lines via a specific receptor显示文摘 | Deshayes F Lapree G Portier A | 2004 | Oncogene2004，23，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员